The lecture is named after Franz M. Hilgendorf (1834-1904), a palaeontologist from Tübingen who, in 1863, constructed the first empirical phylogenetic tree of fossil organisms using snail shells. He thus provided the first fossil proof of gradual evolution and speciation as proposed by Darwin’s theory of evolution.
In memento of this work, the Hilgendorf Lecture series promotes evolutionary thinking across disciplines. Internationally renowned scientists present their latest work or show where evolutionary thinking can inform other research areas. The lecture is open to the public and addresses undergraduate and advanced students, postdocs and members of staff from various fields.
WHEN? Wed 1715 - 1900
|Date||Speaker and Abstract|
06 Dec 2019 (Friday)
Host: Katharina Foerster
Prof. Dr. Mike Bruford (Sustainable Places Research Institute, Cardiff, UK).
Note exceptional time (Friday) and location (Alte Aula, Münzgasse)
Conserving Genomic Diversity in a Changing World
Genomic diversity (GD) is one of the three key components of biological diversity that can be measured, and thirty years of population genetic (and now genomic) research have shown that GD estimators can provide sensitive indictors of changes in demographic processes manifested in population size, connectivity, inbreeding, introgression/hybridization among others. Yet, despite its proven record, GD is rarely incorporated into conservation planning, and we have to ask the question “why?” and examine the prospects for its more meaningful inclusion in conservation policy and management in the future. I will examine the reasons for the limited traction that genetic science has gained in conservation, exemplify some case studies from our own work where genetic and genomic data can fundamentally change conservation management action and discuss prospects for how this situation may improve as we transition into a new decade of conservation planning.
08 Jan 2020
Prof. Dr. Ruth Ley (Department of Microbiome Science, Max Planck Inst. for Developmental Biology, Tübingen)
The role of the microbiome in human genetic adaptation
Human populations have adapted genetically to a variety of local environments across the globe. They have not done so alone, as humans harbour microbiomes acquired from other individuals and from the environment. A subset of host-associated microbes can affect host traits, and these microbes can also be under the genetic influence of the host. Microbiomes can thereby enable or otherwise affect the host’s adaptation to local environments. Our work has highlighted three examples where the microbiome has likely contributed to adaptive trait variation in humans. (1) The strongest association between gut microbiome composition and human genotype is between the human lactate gene (LCT) and the abundance of gut Bifidobacteria. This is true for multiple populations of European descent and is dependent on milk consumption. (2) We have also recently linked the variation in copy number of the salivary amylase gene (AMY1) with the composition and function of the gut microbiome. (3) The gut microbes for which humans have the strongest genetic predisposition belong to the family Christesenellaceae. Intriguingly, these bacteria are also associated with a lean human body type and can induce leanness in mice. Other known examples of local adaptations in humans exist, where future studies may investigate how microbes interact with host adaptive alleles in the process of host adaptive evolution. Despite the potential role of microbiomes in moderating host genetic adaptation, evolutionary models that integrate the interactions between beneficial microbes and beneficial host alleles during the process of host adaptation remain to be developed.
29 Jan 2020
Host: Oliver Bossdorf
Prof. Dr. Carol Lee (Centre of Rapid Evolution, Univ. of Wisconsin)
Note exceptional location (Hörsaal N10, Auf der Morgenstelle 3)
Rapid genomic evolution during habitat invasions
The ability of populations to expand their geographic ranges, whether as invaders, agricultural strains, or climate migrants, presents among the most serious global problems today. However, fundamental mechanisms remain poorly understood regarding factors that enable certain populations, such as biological invaders, to rapidly transition to novel habitats. According to one hypothesis, environmental fluctuations in the