Institute of Organic Chemistry

Fields of research with key publications

Catalysis, Nitrogen Fixation

"Stickstoff-Fixierung und Reduktion zu Ammoniak mit metall-organischen Katalysatoren"
E. Bayer, V. Schurig
Chem. Ber., 102 (1969) 3378.

"Soluble Metal Complexes of Polymers for Catalysis"
E. Bayer, V. Schurig
Angew. Chem. Int. Ed. Engl., 14 (1975) 493.

"A New Class of Catalysts"

V. Schurig, E. Bayer
Chem. Techn. 6 (1976) 212.

"Chiral Polysiloxane-Fixed Metal-1,3-Diketonates (Chirasil-Metals) as Catalytic Lewis Acids of a Hetero Diels-Alder Reaction - Inversion of Enantioselectivity Upon Catalyst-Polymer-Binding"
F. Keller, H. Weinmann, V. Schurig
Chem. Ber./Recueil, 130 (1997) 879-885.

Enantiomeric Analysis

"Gas Chromatographic Methods for Determining Enantiomeric Ratios"
V. Schurig
Asymmetric Synthesis, Vol. I: Analytical Methods (J. D. Morrison, Ed.), Academic Press, New York, Chapter 5 (1983) 59.
Translated into Russian.

"Determination of Enantiomeric Purity by Direct Methods -- Overview, by Chemical Correlation, by Polarimetry, by NMR-Spectroscopy and by Gas Chromatography"
V. Schurig
Houben-Weyl, Methods of Organic Chemistry, Stereoselective Synthesis,
Thieme, Stuttgart, New York, 1995, Vol. E 21 a, p. 147 - 192.
cf. Kontakte (Darmstadt), 1985(1), 54; 1985(2), 22; 1986 (1), 3.

Stereochemical Nomenclature

"Terms for the Quantitation of a Mixture of Stereoisomers"
V. Schurig
Enantiomer, 1 (1996) 139-143.

Stereotopicity Concept

"Stereoheterotopicity and Stereoisomerism in Heterochiral cis vs. trans Olefin Metal p Complexes"
V. Schurig
Tetrahedr. Lett., 25 (1984) 2739.

Chiral Lanthanide Shift Reagents

"Chiral Shift Reagents for NMR Spectroscopy. A Simple and Improved Access to Lanthanide-tris-Chelates of d-3-TFA-Camphor"
V. Schurig
Tetrahedr. Lett., (1972) 3297.

"NMR-Spektroskopischer Nachweis der Chiralität p-komplexierter prochiraler Olefine"
V. Schurig
Tetrahedr. Lett. 1269 (1976).

Olefin-Metall-p-Complexation

"Complexation of Olefins with Planar Rhodium(I) Co-ordination Compounds"
V. Schurig, E. Gil-Av
J. Chem. Soc. D, Chem. Commun., (1971) 650.

"Resolution of a Chiral Olefin by Complexation Chromatography on an Optically Active Rhodium(I) Complex"
V. Schurig
Angew. Chem. Int. Ed. Engl., 16 (1977) 110.

"Relative Stability Constants of Olefin-Rhodium(I) vs. Olefin-Rhodium(II) Coordination as Determined by Complexation Gas Chromatography"
V. Schurig
Inorg. Chem. 25 (1986) 945.

Chiral Complexation Chromatography

"Extending the Scope of Enantiomer Resolution by Complexation Gas Chromatography"
V. Schurig, W. Bürkle
J. Amer. Chem. Soc., 104 (1982) 7573.

"Enantiomer Analysis by Complexation Gas Chromatography: Scope, Merits and Limitations"
V. Schurig
J. Chromatogr., 441 (1988) 135.

"Enantiomer Separation by Complexation SFC on Immobilized Chirasil-nickel and Chirasil-zinc"
V. Schurig, M. Fluck
J. Biochem. Biophys. Methods, 43 (2000) 223-240.

"Practice and Theory of Enantioselective Complexation Gas Chromatography"
V. Schurig
J. Chromatogr. A, 965 (2002) 315-356.

Gas-chromatographic Enantiomer Separation

"Gas Chromatographic Separation of Enantiomers on Optically Active Metal-Complex-Free Stationary Phases"
V. Schurig
Angew. Chem. Int. Ed. Engl., 23 (1984) 747.

"Gas chromatographic Separation of Enantiomers on Cyclodextrin Derivatives"
V. Schurig, H.-P. Nowotny
Angew. Chem. Int. Ed. Engl., 29 (1990) 939.

"Gas Chromatography - Techniques, Chiral Separations"
V. Schurig
Encyclopedia of Analytical Science, Academic Press, London, 1995, Vol. 3, 1851-1860.

Analysis of Chiral Insect Pheromones and Flavours

"Complexation Gas Chromatography - A Valuable Tool for the Stereochemical Analysis of Pheromones"
R. Weber, V. Schurig
Naturwissenschaften, 71 (1984) 408.

"Enantiomer Separation by Complexation Gas Chromatography - Applications in Chiral Analysis of Pheromones and Flavours"
V. Schurig
Bioflavour '87 (P. Schreier, Ed.), de Gruyter, Berlin, 1988, 35.

Chiral Electrochromatography

"Enantiomer Separation by Electrochromatography in Open Tubular Columns Coated with Chirasil-Dex"
S. Mayer, V. Schurig
J. Liq. Chromatogr., 16 (1993) 915.

"Separation of Enantiomers by Open Capillary Electrochromatography on Polysiloxane-bonded Permethyl-b-cyclodextrin"
V. Schurig, S. Mayer
J. Biochem. Biophys. Methods, 48 (2001) 117.

Monoliths in Electrochromatography

"Enantiomer Separation by Capillary Electrochromatography on a Cyclodextrin-modified Monolith"
D. Wistuba, V. Schurig
Electrophoresis, 21 (2000) 3152-3159.

"A Silica Monolithic Column Prepared by the Sol-Gel Process for Enantiomeric Separation by Capillary Electrochromatography"
J. Kang, D. Wistuba, V. Schurig
Electrophoresis, 23 (2002) 1116-1120.

Unified Enantioselective Chromatography

"Toward Unified Enantioselective Chromatography with a Single Capillary Column Coated with Chirasil-Dex"
V. Schurig, M. Jung, S. Mayer, S. Negura, M. Fluck, H. Jakubetz
Angew. Chem. Int. Ed. Engl., 33 (1994) 2222.

Enantiomerization

"Determination of Enantiomerization Barriers by Computer Simulation of Interconversion Profiles: Enantiomerization of Diaziridines during Chiral Inclusion Gas Chromatography"
M. Jung, V. Schurig
J. Amer. Chem. Soc., 114 (1992) 529.

"Probing the Stereointegrity of Tröger's Base - A Dynamic Electrokinetic Chromatographic Study"
O. Trapp, G. Trapp, J. W. Kong, U. Hahn, F. Vögtle, V. Schurig
Europ. J. Chem., 8 (2002) 3629-3634.

"Determination of the Enantiomerization Barrier of Thalidomide by Dynamic Capillary Electrocinetic Chromatography"
G. Schoetz, O. Trapp, V. Schurig
Electrophoresis, 22 (2001) 3185-3190.

Stopped Flow Gas Chromatography

"Stopped-Flow Multidimensional GC - A New Method for the Determination of Enantiomerization Barriers"
S. Reich, V. Schurig
J. Microcol. Sep., 11 (1999) 475-479.

Enantioselective Coalescence Phenomena

"Peak Coalescence Phenomena in Enantioselective Chromatography"
V. Schurig
Chirality, 10 (1998) 140-146.

Synthesis of Chiral Oxiranes

"(S)-2-Chloroalkanoic Acids of High Enantiomeric Purity from (S)-2-Amino Acids"
B. Koppenhoefer, V. Schurig
Organic Syntheses, 66 (1987) 151.

"(R)-Alkyloxiranes of High Enantiomeric Purity from (S)-2-Chloro-alkanoic Acids via (S)-2-chloro-1-alkanols: (R)-Methyloxirane"
B. Koppenhoefer, V. Schurig
Organic Syntheses, 66 (1987) 160.

Enantioselective Epoxidations

"Cytochrome P-450-Catalyzed Asymmetric Epoxidation of Simple Prochiral and Chiral Aliphatic Alkenes: Species Dependence and Effect of Enzyme Induction on Enantioselective Oxirane Formation"
D. Wistuba, H.-P. Nowotny, O. Tröger, V. Schurig
Chirality, 1 (1989) 127.

"Enantio- and Regioselectivity in the Epoxide-Hydrolase-catalyzed Ring Opening of Simple Aliphatic Oxiranes"
D. Wistuba, V. Schurig
Chirality, 4 (1992) 178 & 185.

"Metal-mediated Enantioselective Access to Unfunctionalized Aliphatic Oxiranes: Prochiral and Chiral Recognition"
V. Schurig, F. Betschinger
Chem. Rev., 92 (1992) 873.

Chiral Solid State Phenomena

"Chirodichroism of Different Enantiomeric Compositions of a Planar d8-Metal Complex"
V. Schurig
Angew. Chem. Int. Ed. Engl., 20 (1981) 807.

"Helical Conformation and Stereoisomerism in the Solid State: The Crystal Structures of Helical Enantiomerically Pure and Racemic [HFG(3,3'-Bis(camphorato))]bis(dicarbonylrhodium(I))"
P. Scheer, V. Schurig
Synthetic Metals, 43 (1991) 4071.

Chiral Inhalation Anesthetics

"Enantiomer Separation of Chiral Inhalation Anesthetics (Enflurane, Isoflurane and Desflurane) by Gas Chromatography on a Cyclodextrin Derivative"
V. Schurig, M. Juza, H. Grosenick
Recl. Trav. Chim. Pays-Bas, 114 (1995) 211.

Chiral Calixarenes

"Synthesis of Chiral Calix[n]arenes. Part 2: Synthesis of new Chiral Calix[n]arenes Based on (p-Hydroxy-phenyl)-menthone"
A. Soi, J. Pfeiffer, J. Jauch, V. Schurig
Tetrahedr. Asymmetry, 10 (1999) 177-182.

"Synthesis of an Enantiomerically Pure Resorcarene with Pendant L-Valine Residues and its Attachment to a Polysiloxane (Chirasil-Calix)"
A. Ruderisch, J. Pfeiffer, V. Schurig
Tetrahedr. Asymm., 12 (2001) 2025-2030.

Fullerene

"Enantiomer Separation of [60]Fullerene Derivatives with an Inherent Chiral Addition Pattern"
B. Gross, V. Schurig, I. Lamparth, A. Herzog, F. Djojo, A. Hirsch
J. Chem. Soc., Chem. Comm., (1997) 1117-1118.

"Enantiomer Separation of [60]Fullerene Derivatives by Micro-Column-HPLC Using
(R)-(-)-TAPA as Chiral Stationary Phase"

B. Gross, V. Schurig, I. Lamparth, A. Hirsch
J. Chromatogr. A, 791 (1997) 65-69.

"Retention Behaviour of Polychlorinated Biphenyls on Polysiloxane-anchored C60 in Gas Chromatography"
A. Glausch, A. Hirsch, I. Lamparth, V. Schurig
J. Chromatogr. A, 809 (1998) 252-257.

Chiral Environmental Organochlorines

"Enantiomer Separation of Atropisomeric Polychlorinated Biphenyls (PCBs) by Gas Chromatography on Chirasil-Dex"
V. Schurig, A. Glausch
Naturwissenschaften, 80 (1993) 468.

"Enantiomerization of Environmentally Significant Overcrowded Polychlorinated Biphenyls (PCBs): A Computational Approach"
P. U. Biedermann, V. Schurig, I. Agranat
Chirality, 9 (1997) 350-353.

"Determination of the Rotational Barrier of Atropisomeric Polychlorinated Biphenyls (PCBs) by a Novel Stopped-Flow Multidimensional Gas Chromatographic Technique"
V. Schurig, S. Reich
Chirality, 10 (1998) 316-320. Reprinted in the Gil-Av Memorial Issue: 10 (1998) 425-429.

Enantioselective Antibodies

"Antibodies Can Recognize the Chiral Center of Free alpha-Amino Acids"
O. Hofstetter, H. Hofstetter, V. Schurig, M. Wilchek, B. S. Green
J. Amer. Chem. Soc., 120 (1998) 3251-3252.

"An Immunochemical Approach for the Determination of Trace Amounts of Enantiomeric Impurities"
O. Hofstetter, H. Hofstetter, M. Wilchek, V. Schurig, B. S. Green
J. Chem. Soc., Chem. Comm., (2000) 1581-1582.

"Production and Applications of Antibodies Directed Against the Chiral Center of a-Amino Acids"
O. Hofstetter, H. Hofstetter, M. Wilchek, V. Schurig, B. S. Green
Int. J. Bio-Chromatogr., 5 (2000) 165-174.

Enantioselective Sensors

"Chiral Discrimination of Limonene by Use of b-Cyclodextrin-coated Quartz-Crystal-Microbalances (QCMs) and Data Evaluation by Artificial Neuronal Networks"
C. Fietzek, T. Hermle, W. Rosenstiehl, V. Schurig
Fresenius J. Anal. Chem., 371 (2001) 58-63.

Chiral Immunosensor

"Chiral Discrimination Using an Immunosensor"
O. Hofstetter, H. Hofstetter, M. Wilchek, V. Schurig, B. Green
Nature Biotechnology, 17 (1999) 371-374.

Exochirality

"Search for Extraterrestrial Enantioenrichment by Using Chemical Microsensors"
A. Hierlemann, H. Baltes, V. Schurig
Enantiomer, 6 (2001) 129-139.

"Interconversion of Chiral Molecules in Interstellar Space"
O. Trapp, V. Schurig
Enantiomer, 6 (2001) 193-194.

Combinatorial Selectors

"Cyclopeptidbibliotheken als neue chirale Selektoren für die Kapillarelektrophorese (Cyclopeptide Libraries as New Selectors for Capillary Electrophoresis)"
G. Jung, H. Hofstetter, S. Feiertag, D. Stoll, O. Hofstetter, K.-H. Wiesmüller, V. Schurig
Angew. Chem., 108 (1996) 2261-2263; Angew. Chem. Int. Ed. Engl. 35 (1996) 2148-2150.