Google Scholar:


Recent publications


  • Ajibola, A., Tisler, S. and Zwiener, C. (2020) Simultaneous determination of multiclass antibiotics in sewage sludge based on QuEChERS extraction and liquid chromatography-tandem mass spectrometry. Analytical Methods.
  • Bugsel, B. and Zwiener, C. (2020) LC-MS screening of poly- and perfluoroalkyl substances in contaminated soil by Kendrick mass analysis. Analytical and Bioanalytical Chemistry.
  • Evlampidou, I., Font-Ribera, L., Rojas-Rueda, D., Gracia-Lavedan, E., Costet, N., Pearce, N., Vineis, P., Jaakkola, J.J.K., Delloye, F., Makris, K.C., Stephanou, E.G., Kargaki, S., Kozisek, F., Sigsgaard, T., Hansen, B., Schullehner, J., Nahkur, R., Galey, C., Zwiener, C., Vargha, M., Righi, E., Aggazzotti, G., Kalnina, G., Grazuleviciene, R., Polanska, K., Gubkova, D., Bitenc, K., Goslan, E.H., Kogevinas, M. and Villanueva, C.M. (2020) Trihalomethanes in Drinking Water and Bladder Cancer Burden in the European Union. Environmental Health Perspectives 128(1), 017001.
  • Glaser, C., Zarfl, C., Werneburg, M., Böckmann, M., Zwiener, C. and Schwientek, M. (2020) Temporal and spatial variable in-stream attenuation of selected pharmaceuticals. Science of the Total Environment 741, 139514.   DOI: 10.1016/j.scitotenv.2020.139514
  • Lege, S., Sorwat, J., Yanez Heras, J.E. and Zwiener, C. (2020) Abiotic and biotic transformation of torasemide - Occurrence of degradation products in the aquatic environment. Water Research 177, 115753.   DOI: 10.1016/j.watres.2020.115753
  • Müller, M.E., Werneburg, M., Glaser, C., Schwientek, M., Zarfl, C., Escher, B.I. and Zwiener, C. (2020) Influence of emission sources and tributaries on the spatial and temporal patterns of micropollutant mixtures and associated effects in a small river. Environmental Toxicology and Chemistry 39(7), 1382-1391.   DOI: 10.1002/etc.4726
  • Ziegler, M., Knoll, S., Köhler, H.-R., Tisler, S., Huhn, C., Zwiener, C. and Triebskorn, R. (2020) Impact of the antidepressant citalopram on the behaviour of two different life stages of brown trout. PeerJ 8, e8765.   DOI: 10.7717/peerj.8765
  • Zindler, F., Tisler, S., Loerracher, A.-K., Zwiener, C. and Braunbeck, T. (2020) Norfluoxetine Is the Only Metabolite of Fluoxetine in Zebrafish (Danio rerio) Embryos That Accumulates at Environmentally Relevant Exposure Scenarios. Environmental Science & Technology.   DOI: 10.1021/acs.est.9b07618


  • Balasooriya, S., Munasinghe, H., Herath, A.T., Diyabalanage, S., Ileperuma, O.A., Manthrithilake, H., Daniel, C., Amann, K., Zwiener, C., Barth, J.A.C. and Chandrajith, R. (2019) Possible links between groundwater geochemistry and chronic kidney disease of unknown etiology (CKDu): an investigation from the Ginnoruwa region in Sri Lanka. Exposure and Health.
  • Font-Ribera, L., Marco, E., Grimalt, J.O., Pastor, S., Marcos, R., Abramsson-Zetterberg, L., Pedersen, M., Grummt, T., Junek, R., Barreiro, E., Heederik, D., Spithoven, J., Critelli, R., Naccarati, A., Schmalz, C., Zwiener, C., Liu, J., Zhang, X., Mitch, W., Gracia-Lavedan, E., Arjona, L., de Bont, J., Tarès, L., Vineis, P., Kogevinas, M. and Villanueva, C.M. (2019) Exposure to disinfection by-products in swimming pools and biomarkers of genotoxicity and respiratory damage – The PISCINA2 Study. Environment International 131, 104988.
  • Guillet, G., Knapp, J.L.A., Merel, S., Cirpka, O.A., Grathwohl, P., Zwiener, C. and Schwientek, M. (2019) Fate of wastewater contaminants in rivers: Using conservative-tracer based transfer functions to assess reactive transport. Science of the Total Environment 656, 1250-1260.
  • Jacob, S., Knoll, S., Huhn, C., Köhler, H.-R., Tisler, S., Zwiener, C. and Triebskorn, R. (2019) Effects of guanylurea, the transformation product of the antidiabetic drug metformin, on the health of brown trout (Salmo trutta f. fario). PeerJ 7, e7289.
  • Jacob, S., Köhler, H.-R., Tisler, S., Zwiener, C. and Triebskorn, R. (2019) Impact of the Antidiabetic Drug Metformin and Its Transformation Product Guanylurea on the Health of the Big Ramshorn Snail (Planorbarius corneus). Frontiers in Environmental Science 7(45).
  • Janda, J., Nödler, K., Scheurer, M., Happel, O., Nürenberg, G., Zwiener, C. and Lange, F.T. (2019) Closing the gap – inclusion of ultrashort-chain perfluoroalkyl carboxylic acids in the total oxidizable precursor (TOP) assay protocol. Environmental Science: Processes & Impacts (21), 1926-1935.
  • Lege, S., Eisenhofer, A., Heras, J.E.Y. and Zwiener, C. (2019) Identification of transformation products of denatonium – Occurrence in wastewater treatment plants and surface waters. Science of the Total Environment 686, 140-150.
  • Müller, M.E., Vikstrom, S., König, M., Schlichting, R., Zarfl, C., Zwiener, C. and Escher, B.I. (2019) Mitochondrial toxicity of selected micropollutants, their mixtures and surface water samples measured by the oxygen consumption rate in cells. Environmental Toxicology and Chemistry 38(5), 1000-1011.
  • Timm, A., Borowska, E., Majewsky, M., Merel, S., Zwiener, C., Bräse, S. and Horn, H. (2019) Photolysis of four βlactam antibiotics under simulated environmental conditions: Degradation, transformation products and antibacterial activity. Science of the Total Environment 651, 1605-1612.
  • Tisler, S., Zindler, F., Freeling, F., Nödler, K., Toelgyesi, L., Braunbeck, T. and Zwiener, C. (2019) Transformation Products of Fluoxetine Formed by Photodegradation in Water and Biodegradation in Zebrafish Embryos (Danio rerio). Environmental Science & Technology 53, 7400-7409.
  • Tisler, S. and Zwiener, C. (2019) Aerobic and anaerobic formation and biodegradation of guanyl urea and other transformation products of metformin. Water Research 149, 130-135.
  • van Veldhoven, K., Keski-Rahkonen, P., Barupal, D.K., Villanueva, C.M., Font-Ribera, L., Scalbert, A., Bodinier, B., Grimalt, J.O., Zwiener, C., Vlaanderen, J., Portengen, L., Vermeulen, R., Vineis, P., Chadeau-Hyam, M. and Kogevinas, M. (2018) Effects of exposure to water disinfection by-products in a swimming pool: A metabolome-wide association study. Environment International 111, 60-70.

Book chapters

  • C. Zwiener, T.J. Gremm, F.H. Frimmel: Pharmaceutical Residues in the Aquatic environment and their Significance for Drinking Water Production. In: Kümmerer K. (Ed.): Pharmaceuticals in the environment: Sources, fate, effects and risks. Springer, Berlin, pp. 81-89 (2001).
  • C. Zwiener, F.H. Frimmel: Water Quality. In: W. Kleiboehmer, Handbook of Analytical Separation Vol 3: Environmental Analysis, Elsevier, Amsterdam, pp. 277-318 (2001).
  • C. Zwiener, G. Ohlenbusch, F.H. Frimmel: Analysis and occurrence of nitrogen-heterocyclic and polyaromatic compounds and their transformation products in the subsurface at a contaminated site. In: H.D. Schulz, A. Hadeler (Eds.), Geochemical Processes in Soil and Groundwater: Measurement – Modelling – Upscaling, Wiley-VCH, Weinheim, pp. 224-238 (2003).
  • C. Zwiener, T. Glauner, F.H. Frimmel: Liquid chromatography/electrospray ionization tandem mass spectrometry and derivatization for the identification of polar carbonyl disinfection by-products. In: I. Ferrer, E.M. Thurman (Eds.), Liquid Chromatography/Mass Spectrometry, MS/MS and Time-of-Flight MS – Analysis of Emerging Contaminants. ACS Symposium Series, Vol. 850, Chapter 21, American Chemical Society and Oxford University Press, Washington, pp 356-375 (2003).
  • C. Zwiener, F.H. Frimmel: Organic trace analysis by GC-ITD/MS and LC-ESI/MS/MS applied to MX and other disinfection by-products in water treatment. In: P.A. Wilderer, J. Zhu, N. Schwarzenbeck (Eds.), Water in China - Water and Environmental Management Series, IWA Publishing, London, pp 59-67 (2003).
  • C. Zwiener, F.H. Frimmel: Residues of clofibiric acid, ibuprofen and diclofenac in the aquatic environment and their elimination in sewage treatment and drinking water production. In: Kümmerer K. (Ed.), Pharmaceuticals in the environment: Sources, fate, effects and risks. 2nd Ed., Chapter 9, Springer, Berlin, pp. 121-132 (2004).
  • F. Saravia, C. Zwiener, F. H. Frimmel: Der Einfluss von Ladung und Ionenstärke auf den Membranrückhalt. In: Melin T., Dohmann M. (Eds.), 6. Aachener Tagung, Siedlungswasser¬wirt-schaft und Verfahrenstechnik, Aachen (2005).
  • C. Zwiener: THMs, HAAs, and Emerging Disinfection By-products in Drinking Water. In: Reemtsma T., Jekel M. (Eds.): Organic pollutants in the water cycle. Wiley-VCH, Weinheim, pp. 251-286 (2006).
  • C. Zwiener: Verhalten von Arzneimittelrückständen bei der Trinkwasseraufbereitung. In: Frimmel F.H., Müller M. (Eds.): Heil-Lasten – Arzneimittelrückstände in Gewässern, Springer, Berlin, pp. 207-224 (2006).
  • C. Zwiener: Environmental Applications: Strategies for the GC-MS and LC-MS analysis of endocrine disruptors in environmental compartments. In: Niessen W.M.A. (Vol.-Ed.), Gross M.L.., Caprioli R.M. (Eds.-In-Chief): Encyclopedia of mass spectrometry, Vol. 8: Hyphenated methods, pp. 603-610, Elsevier Science, Oxford, (2006).
  • T. Glauner, C. Zwiener, F.H. Frimmel: Minimierung von Desinfektionsnebenprodukten unter Berücksichtigung chemischer Aspekte und neuer Aufbereitungstechnologien. In: Projektträger Forschungszentrum Karlsruhe (PTKA), Bereich Wassertechnologie und Entsorgung (WTE) (Ed.): Abschlussbericht des Forschungsverbundvorhabens „Sicherheit von Schwimm- und Badebeckenwasser aus gesundheitlicher und aufbereitungstechnischer Sicht, Dresden (2006).
  • F. Tiefenbrunner, C. Zwiener: Badewasser, S.867-894. In: Karl Höll: Wasser - Nutzung im Kreislauf - Hygiene, Analyse und Bewertung, 9. Auflage, Nießner, R. (Ed.), Berlin, De Gruyter (2010).
  • C. Zwiener, C. Schmalz: Ion Mobility Spectrometry to Monitor Trichloramine in Indoor Pool Air. In: Karanfil T., Mitch B., Westerhoff P., Xie Y. (Eds.) Recent Advances in Disinfection By-Products, ACS Symposium Series Vol. 1190, Chapter 22, pp 431-446, American Chemical Society and Oxford University Press, Washington, (2015).
  • S. Merel, C. Zwiener: Accurate Mass Screening and Data Evaluation Approaches for Ozonation by-Products in Wastewater Treatment Plant Effluents. In: J. E. Drewes and T. Letzel (Eds.), Assessing Transformation Products of Chemicals by Non-Target and Suspect Screening Strategies and Suspect Screening − Strategies and Workflows. ACS Symposium Series Vol. 1242, Chapter 1 (Vol. 2), pp3-27, American Chemical Society, Washington, DC (2016).