26.06.2018

Modeling of metabolism and gene expression in SBML

First draft for a uniform standard for storing ME models in SBML developed.

In his master thesis, Marc Alexander Voigt laid the foundation for a uniform standard for the description of ME models in the SBML file format. These are systems biology models that link metabolism with effects of gene expression. For a long time, these processes could only be described separately. When models were finally developed that combined both, there was a lack of a suitable format for data exchange between different simulators. The work was carried out in close cooperation with colleagues from the University of California in San Diego and also in consultation with colleagues from Paris and Luxembourg.