Nantia Leonidou

M.Sc. in Bioinformatics

Office

Department for Computer Science
Institute for Bioinformatics and Medical Informatics
Sand 14 ・ Main Floor ・ Office C107
 +49-7071-29-70452
 nantia.leonidou@uni-tuebingen.de

 
Bibliography

Google-Scholar-Profil
NCBI-Pubmed-Profil

Social Media

 Twitter Account
ORCID Account
GitHub Profile

 


Academic Qualifications


Research interests

  • Molecular Biology / Molecular Medicine:
    Understanding the molecular, biochemical and metabolic mechanisms in prokaryotes and eukaryotes in health and disease

  • Systems Biology:

    In silico constraint-based reconstruction and analysis of biochemical networks
    • Eukaryotic biochemical models

    • Host-pathogen biochemical models; Analysis of infections mechanisms between pathogens and their host

    • Microbial metabolic reconstructions & Microbial community interactions

  • Visualization:

    • Visualization and interpretation of metabolic processes

    • Creation of metabolic pathways maps


Current research projects

Identification of robust antiviral drug targets against SARS-CoV-2

This start-up project supports the identification of robust targets for the treatment of COVID-19 to be experimentally verified in subsequent projects.

Funded by the Federal Ministry of Education and Research (BMBF) and the Baden-Württemberg Ministry of Science as part of the Excellence Strategy of the German Federal and State Governments.

Computer Modeling and Experimental Validation of Microbial Interactions
Collaborative Project

The project № EXC-2124/05.037_0 is funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation, doi:10.13039/501100001659) under Germanyʼs Excellence Strategy – EXC 2124 – 390838134 and supported by the Cluster of Excellence CMFI (Controling Microbes to Fight Infections) from May 2021 to April 2024 as a collaboration with the group of Dr. Simon Heilbronner.


Publications


Teaching

Winter term 2016 until summer term 2021

Mathematics

Summer term 2021

Bioinformatics Preparatory Course

The Bioinformatics Vorkurs aims at introducing students to the basic computational issues. It is not going to cover entire programming taught in the Bachelor Bioinformatics course, rather it is meant to provide a starting point for those who are planning a career in bioinformatics, but have no experience with Linux-like systems and programming. It is a Vorkurs, therefore no ECTS points are awarded.

Please see https://bioinfprep.github.io for further information about this course.

Systems Biology II: Simulation of Dynamic Network States (BIOINF4394)

Lecture with Excercises

Because of the worldwide COVID-19 pandemic, this course will take place this semester as a flipped classroom course on tuesdays at 2 p.m. c.t. via ZOOM. The weekly tutorial session is taking place on thursdays at 2 p.m. c.t. via ZOOM. The corresponding Alma page provides more detailed information. If you encounter any difficulties to access the information, please contact Jun.-Prof. Dr. Andreas Dräger.

Winter term 2021/2022

Bioinformatics Preparatory Course

The Bioinformatics Vorkurs aims at introducing students to the basic computational issues. It is not going to cover entire programming taught in the Bachelor Bioinformatics course, rather it is meant to provide a starting point for those who are planning a career in bioinformatics, but have no experience with Linux-like systems and programming. It is a Vorkurs, therefore no ECTS points are awarded.

Please see https://bioinfprep.github.io for further information about this course.

Systems Biology I: Constraint-Based Reconstruction and Analysis (BIOINF3371)

Lecture with Excercises

Lecturer: Jun.-Prof. Dr. Andreas Dräger
Tutor: M.Sc. Nantia Leonidou

The language of this lecture is English. For further information, please see the Syllabus document linked below and the entry in the Alma system.

Summer term 2022

Systems Biology II: Simulation of Dynamic Network States (BIOINF4394)

Lecture with Excercises

In case of any questions regarding this class, please do not hesitate to contact your lecturer, Dr. Reihaneh Mostolizadeh, or your tutor, M.Sc. Nantia Leonidou.

Winter term 2022/2023

Mathematics of life: Modelling molecular mechanisms

Virtual lecture series in English

This lecture is virtually conducted by the European Bioinformatics Institute (EMBL-EBI) with contribution by Jun.-Prof. Dr. Andreas Dräger. For further information, see the website of the class.

Topic: “Introduction to Constraint-Based Reconstruction and Modeling”, September 14th, 2022 at 10:30 a.m. British Summer Time, i.e., 11:30 a.m. German time.

Fundametals of Systems Biology

Introductory Seminar Course

Instructors: Jun. Prof. Dr. Andreas Dräger and M.Sc. Nantia Leonidou

Alma
ILIAS Syllabus

Talks and Posters

Posters

  1. Tissue-specific reconstruction of constraint-based metabolic models based on ReconX 
    7th Conference on Constraint-Based Reconstruction and Analysis (COBRA), virtual, 1-2 March, 2021
  2. New Workflow Predicts Drug Targets Against Sars-Cov-2 Via Metabolic Changes in Infected Cells
    DGI-DZIF Joint Annual Meeting (Link), Stuttgart, 1-3 June, 2022
  3. New Workflow Predicts Drug Targets Against Sars-Cov-2 Via Metabolic Changes in Infected Cells
    30th Conference on Intelligent Systems for Molecular Biology (SysMod@ISMB), Madison, United States, 10-14 June, 2022
  4. Manually Curated Genome-Scale Metabolic Reconstructions of the Multi-Drug Resistant Gram-Negative Pathogens A. Baumannii and K. Pneumoniae
    8th Conference on Constraint-Based Reconstruction and Analysis (COBRA), Galway, Ireland, 28-30 September, 2022
  5. New Workflow Predicts Drug Targets Against Sars-Cov-2 Via Metabolic Changes in Infected Cells
    8th Conference on Constraint-Based Reconstruction and Analysis (COBRA), Galway, Ireland, 28-30 September, 2022

 

Talks

  1. Tissue-specific reconstruction of constraint-based metabolic models based on ReconX
  2. New Workflow Predicts Drug Targets Against SARS-CoV-2 via Metabolic Changes in Infected Cells
    HARMONY, hybrid, 26-30 April 2022
  3. Computational Systems Biology of Infection and Antimicrobial Resistance
    DZIF TTU HAARBI Retreat, Frankfurt, Germany, 22-23 June, 2022 (on behalf of Jun. -Prof. Dr. Andreas Dräger)
  4. Manually Curated Genome-Scale Metabolic Reconstructions of the Multi-Drug Resistant Gram-Negative Pathogens A. Baumannii and K. Pneumoniae
    21st International Conference on Systems Biology (ICSB), Berlin, Germany, 8-12 October, 2022
  5. New Workflow Predicts Drug Targets Against Sars-Cov-2 Via Metabolic Changes in Infected Cells
    21st International Conference on Systems Biology (ICSB), Berlin, Germany, 8-12 October, 2022

 


Awards and honors

  1. ILW Recognition Award 2020/21
  2. Apolytirion with distinction from the 5th Lyceum in Kavala, Greece

 



Further Training