Pharmacology, Toxicology and Clinical Pharmacy


[18] Matt, L., Kim, K., Chowdhury, D. and Hell, J.W. (2019). Role of palmitoylation of postsynaptic proteins in promoting synaptic plasticity. Front Mol Neurosci 12.


[17] Singer, W., Manthey, M., Panford-Walsh, R., Matt, L., Geisler, H.S., Passeri, E., Baj, G., Tongiorgi, E., Leal, G., Duarte, C.B. and Salazar, I.L., Eckert P., Rohbock K., Hu J., Strotmann J., Ruth P., Zimmermann U., Rüttiger L., Ott T., Schimmang T., Knipper M., (2018). BDNF-Live-Exon-Visualization (BLEV) allows differential detection of BDNF transcripts in vitro and in vivo. Front Mol Neurosci 11.
[16] Matt, L., Eckert, P., Panford-Walsh, R., Geisler, H. S., Bausch, A., Manthey M., Müller N. I. C., Harasztosi C., Rohbock K., Ruth P., Friauf E., Ott T., Zimmermann U., Rüttiger L., Schimmang T., Knipper M., Singer W. (2018). Visualizing BDNF transcript usage during sound-induced memory linked plasticity. Front Mol Neurosci 11.

Matt, L., Kim, K., Hergarden, A.C., Patriarchi, T., Malik, Z.A., Park, D.K., Chowdhury, D., Buonarati, O.R., Henderson, P.B., Gokcek Sarac, C., Zhang, Y., Mohapatra, D., Horne, M.C., Ames, J.B., Hell, J.W. (2018). alpha-Actinin Anchors PSD-95 at Postsynaptic Sites. Neuron 97, 1094-1109 e1099.


Matt, L., Kirk, L.M., Chenaux, G., Speca, D.J., Puhger, K.R., Pride, M.C., Qneibi, M., Haham, T., Plambeck, K.E., Stern-Bach, Y., Silverman, J.L., Crawley, J.N., Hell, J.W., Diaz, E. (2018). SynDIG4/Prrt1 Is Required for Excitatory Synapse Development and Plasticity Underlying Cognitive Function. Cell Rep 22, 2246-2253.




Qian, H., Patriarchi, T., Price, J.L., Matt, L., Lee, B., Nieves-Cintron, M., Buonarati, O.R., Chowdhury, D., Nanou, E., Nystoriak, M.A., Catterall, W.A., Poomvanicha, M., Hofmann, F., Navedo, M.F., Hell, J.W. (2017). Phosphorylation of Ser1928 mediates the enhanced activity of the L-type Ca2+ channel Cav1.2 by the beta2-adrenergic receptor in neurons. Sci Signal 10.




Chenaux, G., Matt, L., Hill, T.C., Kaur, I., Liu, X.B., Kirk, L.M., Speca, D.J., McMahon, S.A., Zito, K., Hell, J.W., Diaz, E. (2016). Loss of SynDIG1 Reduces Excitatory Synapse Maturation But Not Formation In Vivo. eNeuro 3.




Chen, C.Y., Matt, L., Hell, J.W., and Rogawski, M.A. (2014). Perampanel inhibition of AMPA receptor currents in cultured hippocampal neurons. PloS one 9, e108021.


Matt, L., and Hell, J.W. (2014). LTP: GluN2B on the go. The EMBO journal 33, 781-782.


Zhang, Y.*, Matt, L.*, Patriarchi, T., Malik, Z.A., Chowdhury, D., Park, D.K., Renieri, A., Ames, J.B., and Hell, J.W. (2014). Capping of the N-terminus of PSD-95 by calmodulin triggers its postsynaptic release. The EMBO journal 33, 1341-1353. *equal contribution


Speca, D.J., Ogata, G., Mandikian, D., Bishop, H.I., Wiler, S.W., Eum, K., Wenzel, H.J., Doisy, E.T., Matt, L., Campi, K.L., Golub, M.S., Nerbonne, J.M., Hell, J.W., Trainor, B.C., Sack, J.T., Schwartzkroin, P.A., Trimmer, J.S. (2014). Deletion of the Kv2.1 delayed rectifier potassium channel leads to neuronal and behavioral hyperexcitability. Genes Brain Behav 13, 394-408.



Matt, L., and Hell, J.W. (2013). PKClambda: a new player in LTP coming to the rescue of PKCzeta's faltering role in LTP? The EMBO journal 32, 1348-1349.


Hall, D.D., Dai, S., Tseng, P.Y., Malik, Z., Nguyen, M., Matt, L., Schnizler, K., Shephard, A., Mohapatra, D.P., Tsuruta, F., Dolmetsch, R.E., Christel, C.J., Lee, A., Burette, A., Weinberg, R.J., Hell, J.W. (2013). Competition between alpha-actinin and Ca(2)(+)-calmodulin controls surface retention of the L-type Ca(2)(+) channel Ca(V)1.2. Neuron 78, 483-497.


Wang, D., Fu, Q., Zhou, Y., Xu, B., Shi, Q., Igwe, B., Matt, L., Hell, J.W., Wisely, E.V., Oddo, S., Xiang, Y.K. (2013). beta2 adrenergic receptor, protein kinase A (PKA) and c-Jun N-terminal kinase (JNK) signaling pathways mediate tau pathology in Alzheimer disease models. The Journal of biological chemistry 288, 10298-10307.


Zhang, M., Patriarchi, T., Stein, I.S., Qian, H., Matt, L., Nguyen, M., Xiang, Y.K., and Hell, J.W. (2013). Adenylyl cyclase anchoring by a kinase anchor protein AKAP5 (AKAP79/150) is important for postsynaptic beta-adrenergic signaling. The Journal of biological chemistry 288, 17918-17931.



Qian, H., Matt, L., Zhang, M., Nguyen, M., Patriarchi, T., Koval, O.M., Anderson, M.E., He, K., Lee, H.K., and Hell, J.W. (2012). beta2-Adrenergic receptor supports prolonged theta tetanus-induced LTP. Journal of neurophysiology 107, 2703-2712.



Matt, L., Michalakis, S., Hofmann, F., Hammelmann, V., Ludwig, A., Biel, M., and Kleppisch, T. (2011). HCN2 channels in local inhibitory interneurons constrain LTP in the hippocampal direct perforant path. Cell Mol Life Sci 68, 125-137.


Michalakis, S., Kleppisch, T., Polta, S.A., Wotjak, C.T., Koch, S., Rammes, G., Matt, L., Becirovic, E., and Biel, M. (2011). Altered synaptic plasticity and behavioral abnormalities in CNGA3-deficient mice. Genes Brain Behav 10, 137-148.