Bakula D, Müller AJ, Proikas-Cezanne T. WIPI beta-propellers function as scaffolds for STK11/LKB1-AMPK and AMPK-related kinase signaling in autophagy. Autophagy 2017, Epub ahead of print.
Bakula D, Müller AJ, Zuleger T, Takacs Z, Franz-Wachtel M, Thost AK, Brigger D, Tschan MP, Frickey T, Robenek H, Macek B, Proikas-Cezanne T. WIPI3 and WIPI4 beta-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy. Nat Commun. 2017, 8:15637.
Zuleger T, Proikas-Cezanne T. Signal Regulation of WIPI Proteins in Macroautophagy. Chapter 2, Book 'Autophagy and Signaling', Esther Wong (Ed.), CRC Press 2017, ISBN 9781498731898.
Walter C, Clemens LE, Müller AJ, Fallier-Becker P, Proikas-Cezanne T, Riess O, Metzger S, Nguyen HP. Activation of AMPK-induced autophagy ameliorates Huntington disease pathology in vitro. Neuropharmacology. 2016, 108:24-38.
Casas C, Codogno P, Pinti M, Batoko H, Moran M, Proikas-Cezanne T, Reggiori F, Sirko A, Soengas MS, Velasco G, Lafont F, Lane J, Faure M, Cossarizza A. TRANSAUTOPHAGY: European network for interdisciplinary researh and translation of autophagy knowledge. Autophagy. 2016, 12(3):614-7.
Proikas-Cezanne T, Takacs Z, Dönnes P, Kohlbacher O. WIPI proteins: essential PtdIns3P effectors at the nascent autophagosome. J Cell Sci. 2015, 128(2):207-17.
Thost AK, Dönnes P, Kohlbacher O, Proikas-Cezanne T. Fluorescence-based imaging of autophagy progression by human WIPI protein detection. Methods. 2015, 75:69-78.
Takacs Z and Proikas Cezanne T. Human WIPIs as Phosphoinositide Effectors at the Nascent Autophagosome: A Robust Tool to Assess Macroautophagy by Quantitative Imaging. Book “Autophagy”, Volume 7 “Cancer Other Pathologies, Inflammation, Immunity, Infection, And Aging”. Dr. MA Hayat (Ed.), Academic Press, Elsevier, 2015. ISBN: 978-0-12-801043-3.
Pfisterer SG, Bakula D, Cezanne A, Robenek H, Proikas-Cezanne T. WIPI β-propellers on the crossroads of autophagosome and lipid droplet dynamics. Bioch Soc Trans. 2014, 42(5):1414-7.
Brigger D, Proikas-Cezanne T, Tschan MP. WIPI-dependent autophagy during neutrophil differentiation of NB4 acute promyelocytic leukemia cells. Cell Death Dis. 2014, e1315.
Pfisterer SG, Bakula D, Frickey T, Cezanne A, Brigger D, Tschan MP, Robenek H, Proikas-Cezanne T. Lipid droplet and early autophagosomal membrane targeting of Atg2A and Atg14L in human tumor cells. J Lipid Res. 2014, 55:1267-78.
Dupont N, Chauhan S, Arko-Mensah J, Castillo EF, Masedunskas A, Weigert R, Robenek H, Proikas-Cezanne T, Deretic V. Lipase PNPLA5 and neutral lipid stores contribute to autophagosome biogenesis. Curr Biol. 2014, 24(6):609-20.
Burbulla LF, Fitzgerald J, Stegen K, Westermeier J, Thost AK, Kato H, Mokranjac D, Sauerwald J , Martins LM, Woitalla D, Rapaport D, Riess O, Proikas-Cezanne T, Rasse TM, Krüger R. Mitochondrial proteolytic stress induced by loss of mortalin function is rescued by Parkin and PINK1. Cell Death Dis. 2014, 5:e1180.
Bakula D, Zsuzsanna Takacs, Proikas-Cezanne T. WIPI β-propellers in autophagy-related diseases and longevity. Bioch Soc Trans. 2013, 41(4):962-7.
Nemazanyy I, Blaauw B, Paolini C, Caillaud C, Protasi F, Mueller A, Proikas-Cezanne T, Russell RC, Guan KL, Nishino I, Sandri M, Pende M, Panasyuk G. Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease. EMBO Mol Med. 2013, 5(6):870-90.
Tassula Proikas-Cezanne and Daniela Bakula. Role of Human WIPIs in Macroautophagy, Autophagy - A Double-Edged Sword - Cell Survival or Death?, Dr. Yannick Bailly (Ed.), ISBN: 978-953-51-1062-0, InTech 2013, DOI: 10.5772/54601.
Rieter E, Vinke F, Bakula D, Cebollero E, Ungermann C, Proikas-Cezanne T, Reggiori F. Atg18 function in autophagy is regulated by specific sites within its β-propeller. J Cell Sci. 2012, 126:593-604.
Gaugel A, Bakula D, Hoffmann A, Proikas-Cezanne T. Defining regulatory and phosphoinositide-binding sites in the human WIPI-1 β-propeller responsible for autophagosomal membrane localization downstream of mTORC1 inhibition. J Mol Signal. 2012, 7(1):16.
Van der Vos KN, Eliasson P, Proikas-Cezanne T, Vervorrt S, Van Boxtel R, Putker M, Van Zutphen IJ, Mauthe M, Zellmer S, Pals C, Verhagen L, Braat K, Dansen TB, Holstege FCP, Gebhardt R, Burgering BMT, Coffer PJ. Modulation of glutamine metabolism by the PI3K-PKB-FOXO network regulates autophagy. Nat Cell Biol 2012, 14(8):829-37.
Klionsky DJ, … Proikas-Cezanne T, … (multiple authors). Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 2012, 8(4):445-544.
Mauthe M, Yu W, Krut O, Krönke M, Götz F, Robenek, H, Proikas-Cezanne T. WIPI-1 positive autophagosome-like vesicles entrap pathogenic Staphylococcus aureus for lysosomal degradation. ‘Special Issue: Selective Types of Autophagy’, Int J Cell Biol. 2012, 2012:179207.
Proikas-Cezanne T. Zelluläre Homöostase: WIPI-Proteine in der Autophagie humaner Zellen. Zellbiologie und Mikrobiologie - Das Beste aus BIOspektrum, Springer Spektrum Verlag 2012, in german.
Codogno P, Mehrpour M, Proikas-Cezanne T. Canonical and non-canonical autophagy: variations on a common theme of self-eating? Nat Rev Mol Cell Biol. 2011, 13(1):7-12.
Mauthe M, Jacob A, Freiberger S, Hentschel K, Stierhof YD, Codogno P, Proikas-Cezanne T. Resveratrol-mediated autophagy requires WIPI-1 regulated LC3 lipidation in the absence of induced phagophore formation. Autophagy 2011, 7(12):1448-61.
Pfisterer SG, Mauthe M, Codogno P, Proikas-Cezanne T. Ca2+/Calmodulin-Dependent Kinase (CaMK) Signaling via CaMKI and AMP-Activated Protein Kinase Contributes to the Regulation of WIPI-1 at the Onset of Autophagy. Mol Pharmacol. 2011, 80(6):1066-75.
Proikas-Cezanne T, Robenek H. Freeze-fracture replica immunolabelling reveals human WIPI-1 and WIPI-2 as membrane proteins of autophagosomes. J Cell Mol Med. 2011, 15(9):2007-10.
Proikas-Cezanne T. Zelluläre Homöostase: WIPI-Proteine in der Autophagie humaner Zellen. BIOspektrum 2011, 16(5):513-515, in german.
Niessner H, Beck D, Sinnberg T, Lasithiotakis K, Maczey E, Gogel J, Venturelli S, Berger A, Mauthe M, Toulany M, Flaherty K, Schaller M, Schadendorf D, Proikas-Cezanne T, Schittek B, Garbe C, Kulms D, Meier F. The farnesyl transferase inhibitor lonafarnib inhibits mTOR signaling and enforces sorafenib-induced apoptosis in melanoma cells. J Invest Dermatol. 2011, 131(2):468-79.
Gao P, Bauvy C, Souquère S, Tonelli G, Liu L, Zhu Y, Qiao Z, Bakula D, Proikas-Cezanne T, Pierron G, Codogno P, Chen Q, Mehrpour M. The Bcl-2 homology domain 3 mimetic gossypol induces both Beclin 1-dependent and Beclin 1-independent cytoprotective autophagy in cancer cells. J Biol Chem. 2010, 285(33):25570-81.
Geeraert C, Ratier A, Pfisterer SG, Perdiz D, Cantaloube I, Rouault A, Pattingre S, Proikas-Cezanne T, Codogno P, Poüs C. Starvation-induced hyperacetylation of tubulin is required for the stimulation of autophagy by nutrient deprivation. J Biol Chem. 2010, 285(31):24184-94.
Krebiehl G, Ruckerbauer S, Burbulla LF, Kieper N, Maurer B, Waak J, Wolburg H, Gizatullina Z, Gellerich FN, Woitalla D, Riess O, Kahle PJ, Proikas-Cezanne T, Krüger R*. Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1. PLoS One 2010, 5(2):e9367.
Grotemeier A, Alers S, Pfisterer SG, Paasch F, Daubrawa M, Dieterle A, Viollet B, Wesselborg S, Proikas-Cezanne T, Stork B. AMPK-independent induction of autophagy by cytosolic Ca2+ increase. Cell Signal. 2010, 22(6):914-25.
Dhanasekaran DN, Radhika V, Proikas-Cezanne T, Jayaraman M, Ha J. Heterologous expression of olfactory receptors for targeted chemosensing. Ann N Y Acad Sci. 2009, 1170:157-60.
Vergne I, Roberts E, Elmaoued RA, Tosch V, Delgado MA, Proikas-Cezanne T, Laporte J, Deretic V. Control of autophagy initiation by phosphoinositide 3-phosphatase Jumpy. EMBO J. 2009, 28(15):2244-58.
Soskić V, Klemm M, Proikas-Cezanne T, Schwall GP, Poznanović S, Stegmann W, Groebe K, Zengerling H, Schoepf R, Burnet M, Schrattenholz A. A connection between the mitochondrial permeability transition pore, autophagy, and cerebral amyloidogenesis. J Proteome Res. 2008, 7(6):2262-9.
Klionsky DJ, … Proikas-Cezanne T, … (multiple authors). Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 2008, 4(2):151-75.
Proikas-Cezanne T, Ruckerbauer S, Stierhof YD, Berg C, Nordheim A. Human WIPI-1 puncta-formation: a novel assay to assess mammalian autophagy. FEBS Lett. 2007, 581(18):3396-404.
Radhika V, Proikas-Cezanne T, Jayaraman M, Onesime D, Ha JH, Dhanasekaran DN. Chemical sensing of DNT by engineered olfactory yeast strain. Nat Chem Biol. 2007, 3(6):325-30.
Proikas-Cezanne T, Gaugel A, Frickey T, Nordheim A. Rab14 is part of the early endosomal clathrin-coated TGN microdomain. FEBS Lett. 2006, 580(22):5241-6.
Radhika V, Milkevitch M, Audigé V, Proikas-Cezanne T, Dhanasekaran N. Engineered Saccharomyces cerevisiae strain BioS-1, for the detection of water-borne toxic metal contaminants. Biotechnol Bioeng. 2005, 90(1):29-35.
Proikas-Cezanne T, Waddell S, Gaugel A, Frickey T, Lupas A, Nordheim A. WIPI-1alpha (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy. Oncogene 2004, 23(58):9314-25.
Proikas-Cezanne T, Stabel S, Riethmacher D. Identification of protein tyrosine phosphatase 1B and casein as substrates for 124-v-Mos. BMC Biochem. 2002, 3:6.
Waddell S, Jenkins JR, Proikas-Cezanne T. A "no-hybrids" screen for functional antagonizers of human p53 transactivator function: dominant negativity in fission yeast. Oncogene 2001, 20(42):6001-8.
Puls A, Proikas-Cezanne T, Marquardt B, Propst F, Stabel S. Kinase activities of c-Mos and v-Mos proteins: a single amino acid exchange is responsible for constitutive activation of the 124 v-Mos kinase. Oncogene 1995, 10(4):623-30.
