Stafforst group - Chemical Biology & Biochemistry of Nucleic Acids

Nucleic acids are fantastic molecules. Due to their unique base pairing properties, hybridization between nucleic acids is highly predictable and thus rationally programmable. We develop artifical, RNA-guided machines with the intention to create practical tools for the study and control of basic biochemical processes like RNA processing, translation, or epitranscriptomics. To achieve our goals, we combine chemistry with biotechnology and create tools that we optimize for application inside cells and living organisms.