@article{Keating2020,
  author     = {Keating, Sarah M. and Waltemath, Dagmar and K\"onig, Matthias and Zhang, Fengkai and
    Dr\"ager, Andreas and Chaouiya, Claudine and Bergmann, Frank T. and Finney, Andrew and
    Gillespie, Colin S. and Helikar, Tom\'{a}\v{s} and Hoops, Stefan and Malik-Sheriff, Rahuman S.
    and Moodie, Stuart L. and Moraru, Ion I. and Myers, Chris J. and Naldi, Aur\'elien and Olivier,
    Brett G. and Sahle, Sven and Schaff, James C. and Smith, Lucian P. and Swat, Maciej J. and
    Thieffry, Denis and Watanabe, Leandro and Wilkinson, Darren J. and Blinov, Michael L. and
    Begley, Kimberly and Faeder, James R. and G\'omez, Harold F. and Hamm, Thomas M. and Inagaki,
    Yuichiro and Liebermeister, Wolfram and Lister, Allyson L. and Lucio, Daniel and Mjolsness, Eric
    and Proctor, Carole J. and Raman, Karthik and Rodriguez, Nicolas and Shaffer, Clifford A. and
    Shapiro, Bruce E. and Stelling, Joerg and Swainston, Neil and Tanimura, Naoki and Wagner, John
    and Meier-Schellersheim, Martin and Sauro, Herbert M. and Palsson, Bernhard and Bolouri, Hamid
    and Kitano, Hiroaki and Funahashi, Akira and Hermjakob, Henning and Doyle, John C. and Hucka,
    Michael and Adams, Richard R. and Allen, Nicholas A. and Angermann, Bastian R. and Antoniotti,
    Marco and Bader, Gary D. and \v{C}erven\'y, Jan and Courtot, M\'elanie and Cox, Chris D. and
    Dalle Pezze, Piero and Demir, Emek and Denney, William S. and Dharuri, Harish and Dorier, Julien
    and Drasdo, Dirk and Ebrahim, Ali and Eichner, Johannes and Elf, Johan and Endler, Lukas and
    Evelo, Chris T. and Flamm, Christoph and Fleming, Ronan M.~T. and Fr\"ohlich, Martina and Glont,
    Mihai and Gon\c{c}alves, Emanuel and Golebiewski, Martin and Grabski, Hovakim and Gutteridge,
    Alex and Hachmeister, Damon and Harris, Leonard A. and Heavner, Benjamin D. and Henkel, Ron and
    Hlavacek, William S. and Hu, Bin and Hyduke, Daniel R. and Jong, Hidde and Juty, Nick and Karp,
    Peter D. and Karr, Jonathan R. and Kell, Douglas B. and Keller, Roland and Kiselev, Ilya and
    Klamt, Steffen and Klipp, Edda and Kn\"upfer, Christian and Kolpakov, Fedor and Krause, Falko
    and Kutmon, Martina and Laibe, Camille and Lawless, Conor and Li, Lu and Loew, Leslie M. and
    Machne, Rainer and Matsuoka, Yukiko and Mendes, Pedro and Mi, Huaiyu and Mittag, Florian and
    Monteiro, Pedro T. and Natarajan, Kedar Nath and Nielsen, Poul M.~F. and Nguyen, Tramy and
    Palmisano, Alida and Pettit, Jean-Baptiste and Pfau, Thomas and Phair, Robert D. and
    Radivoyevitch, Tomas and Rohwer, Johann M. and Ruebenacker, Oliver A. and Saez-Rodriguez, Julio
    and Scharm, Martin and Schmidt, Henning and Schreiber, Falk and Schubert, Michael and Schulte,
    Roman and Sealfon, Stuart C. and Smallbone, Kieran and Soliman, Sylvain and Stefan, Melanie I.
    and Sullivan, Devin P. and Takahashi, Koichi and Teusink, Bas and Tolnay, David and Vazirabad,
    Ibrahim and Kamp, Axel von and Wittig, Ulrike and Wrzodek, Clemens and Wrzodek, Finja and
    Xenarios, Ioannis and Zhukova, Anna and Zucker, Jeremy},
  journal    = {Molecular Systems Biology},
  title      = {{SBML Level~3: an extensible format for the exchange and reuse of biological
               models}},
  year       = {2020},
  issn       = {1744-4292},
  month      = aug,
  volume     = {16},
  number     = {8},
  pages      = {e9110},
  publisher  = {John Wiley \& Sons, Ltd},
  address    = {New York, NY, USA},
  abstract   = {Abstract Systems biology has experienced dramatic growth in the number, size, and
    complexity of computational models. To reproduce simulation results and reuse models,
    researchers must exchange unambiguous model descriptions. We review the latest edition of the
    Systems Biology Markup Language (SBML), a format designed for this purpose. A community of
    modelers and software authors developed SBML Level 3 over the past decade. Its modular form
    consists of a core suited to representing reaction-based models and packages that extend the
    core with features suited to other model types including constraint-based models,
    reaction-diffusion models, logical network models, and rule-based models. The format leverages
    two decades of SBML and a rich software ecosystem that transformed how systems biologists build
    and interact with models. More recently, the rise of multiscale models of whole cells and
    organs, and new data sources such as single-cell measurements and live imaging, has precipitated
    new ways of integrating data with models. We provide our perspectives on the challenges
    presented by these developments and how SBML Level 3 provides the foundation needed to support
    this evolution.},
  doi        = {10.15252/msb.20199110},
  keywords   = {computational modeling, file format, interoperability, reproducibility, systems
               biology},
  pdf        = {https://www.embopress.org/doi/epdf/10.15252/msb.20199110},
  url        = {https://www.embopress.org/doi/abs/10.15252/msb.20199110},
  eprint     = {https://www.embopress.org/doi/pdf/10.15252/msb.20199110},
}
