@article{King2015b,
  author   = {King, Zachary A. and Lu, Justin S. and Dr\"ager, Andreas and Miller, Philip C. and
    Federowicz, Stephen and Lerman, Joshua A and Ebrahim, Ali and Palsson, Bernhard O. and Lewis,
    Nathan E.},
  title    = {{BiGG Models: A platform for integrating, standardizing, and sharing genome-scale
    models}},
  journal  = {Nucleic Acids Research},
  abstract = {Genome-scale metabolic models are mathematically-structured
    knowledge bases that can be used to predict metabolic pathway usage and
    growth phenotypes. Furthermore, they can generate and test hypotheses when
    integrated with experimental data. To maximize the value of these models,
    centralized repositories of high-quality models must be established, models
    must adhere to established standards, and model components must be linked to
    relevant databases. Tools for model visualization further enhance their
    utility. To meet these needs, we present BiGG Models
    (\url{http://bigg.ucsd.edu}), a completely redesigned Biochemical, Genetic,
    and Genomic knowledge base. BiGG Models contains more than 75 high-quality,
    manually-curated genome-scale metabolic models. On the website, users can
    browse, search, and visualize models. BiGG Models connects genome-scale
    models to genome annotations and external databases. Reaction and metabolite
    identifiers have been standardized across models to conform to community
    standards and enable rapid comparison across models. Furthermore, BiGG
    Models provides a comprehensive application programming interface (API) for
    accessing BiGG Models with modeling and analysis tools. As a resource for
    highly curated, standardized, and accessible models of metabolism, BiGG
    Models will facilitate diverse systems biology studies and support
    knowledge-based analysis of diverse experimental data.},
  keywords = {genome-scale model, knowledge base, omics data},
  month    = oct,
  year     = {2015},
  doi      = {10.1093/nar/gkv1049},
  url      = {https://nar.oxfordjournals.org/content/44/D1/D515},
  pdf      = {https://nar.oxfordjournals.org/content/early/2015/10/15/nar.gkv1049.full.pdf},
}