@article{Rougny2019,
  author   = {Rougny, Adrien and Tour\'e, Vasundra and Moodie, Stuart and Balaur, Irina and
    Czauderna, Tobias and Borlinghaus, Hanna and Dogrusoz, Ugur and Mazein, Alexander and
    Dr\"ager, Andreas and Blinov, Michael L. and Vill\'eger, Alice C. and Haw, Robin and
    Demir, Emek and Mi, Huaiyu and Sorokin, Anatoly and Schreiber, Falk and Luna, Augustin},
  title    = {{Systems Biology Graphical Notation: Process Description language Level~1 Version~2.0}},
  journal  = {Journal of Integrative Bioinformatics},
  year     = {2019},
  month    = jun,
  day      = {13},
  volume   = {16},
  number   = {2},
  pages    = {},
  abstract = {The Systems Biology Graphical Notation (SBGN) is an international community
    effort that aims to standardise the visualisation of pathways and networks for readers
    with diverse scientific backgrounds as well as to support an efficient and accurate
    exchange of biological knowledge between disparate research communities, industry, and
    other players in systems biology. SBGN comprises the three languages Entity Relationship,
    Activity Flow, and Process Description (PD) to cover biological and biochemical systems
    at distinct levels of detail. PD is closest to metabolic and regulatory pathways found
    in biological literature and textbooks. Its well-defined semantics offer a superior
    precision in expressing biological knowledge. PD represents mechanistic and temporal
    dependencies of biological interactions and transformations as a graph. Its different
    types of nodes include entity pools (e.g. metabolites, proteins, genes and complexes)
    and processes (e.g. reactions, associations and influences). The edges describe
    relationships between the nodes (e.g. consumption, production, stimulation and inhibition).
    This document details Level 1 Version 2.0 of the PD specification, including several
    improvements, in particular: 1) the addition of the equivalence operator, subunit, and
    annotation glyphs, 2) modification to the usage of submaps, and 3) updates to clarify
    the use of various glyphs (i.e. multimer, empty set, and state variable).},
  issn     = {1613-4516},
  doi      = {10.1515/jib-2019-0022},
  url      = {https://www.degruyter.com/view/journals/jib/16/2/article-20190022.xml},
  pdf      = {https://www.degruyter.com/view/journals/jib/16/2/article-20190022.pdf},
  keywords = {biological network; circuit diagram; SBGN; standard; systems biology; visualisation}
}