News

Über den Exzellenzcluster CMFI

Mikrobielle Gemeinschaften, sogenannte Mikrobiome, besiedeln die Oberflächen des menschlichen Körpers. Neben Bakterien, die die menschliche Gesundheit positiv beeinflussen, finden sich im Mikrobiom auch potenziell tödliche Krankheitserreger. Gegen diese Erreger wurden in den vergangenen Jahrzehnten oft Breitbandantibiotika eingesetzt. Inzwischen ist klar, dass dadurch nicht nur die Entstehung von Antibiotikaresistenzen gefördert, sondern in vielen Fällen auch das Mikrobiom als Ganzes geschädigt wird. Die Forscherinnen und Forscher des Exzellenzclusters „Kontrolle von Mikroorganismen zur Bekämpfung von Infektionen“ wollen zur Kontrolle von Infektionen nun eine neue Strategie entwickeln.

Ihr Ziel ist es, neue zielgerichtete Wirkstoffe zu entwickeln, die sich positiv auf Mikrobiome auswirken. So ist bekannt, dass nützliche Bakterien ihre gefährlichen Artgenossen in Schach halten können. Um die zugrundeliegenden Mechanismen zu verstehen und nutzbar zu machen, sollen im Rahmen des Exzellenzclusters Forscherinnen und Forscher aus molekularen, bioinformatischen und klinischen Disziplinen zusammenarbeiten. Sprecher des Clusters sind Professor Andreas Peschel und Professorin Heike Brötz-Oesterhelt vom Interfakultären Institut für Mikrobiologie und Infektionsmedizin der Universität Tübingen sowie Professorin Ruth Ley, Direktorin des Max-Planck-Instituts für Entwicklungsbiologie. Beteiligt sind zudem das Universitätsklinikum Tübingen und das Deutsche Zentrum für Infektionsforschung (DZIF).

Veranstaltungen

03.02.2022

Julia Vorholt, tba

Mikrobiologisches Kolloquium, 03.02.2021 | 12:30 Uhr

Read more

Aktuelle Stellenausschreibungen

PhD Student (EN)

The Bacterial Metabolomics Group of the Cluster of Excellence "Controlling microbes to fight infections" at the University of Tübingen advertises a

PhD Position (m/f/d, E 13 TV-L, 65%)

in Metabolism-Microbiome Interactions

to be filled in May 2022. The position is limited to three years.

The research group Bacterial Metabolomics headed by Prof. Dr. Hannes Link is looking for a PhD student to investigate metabolic interactions in microbiomes. The possibility to work on a PhD thesis is given. The successful candidate will develop computational methods to examine microbiomes with mass spectrometry-based metabolomics data and devise strategies to engineer microbiomes. Our group develops novel metabolomics methods with applications in various research areas such as microbiome research and metabolic engineering. You can find more information about our group at https://www.linkmetabolism.com.

Your tasks:

  • Identification of metabolism-microbe interactions: Development of machine learning methods that predict metabolic interactions in microbial communities based on metabolomics and gene expression data.
  • Mapping bacterial communities: Development of computational tools to map the structure of bacterial communities to mass spectrometry data.
  • Metabolomics data analysis: Convert spectral data into chemically annotated compounds. Generate spectral reference databases from in-house strain libraries.
  • Predict targets for microbiome engineering: Systematic analysis of large metabolomics data sets to infer novel strategies to control healthy microbiomes and prevent microbiome related diseases.

Our requirements:

  • Master degree in bioinformatics, computer science, biotechnology or a related subject.
  • Excellent communication skills in English, both written and spoken
  • Excellent programming skills (Python, MATLAB or a related language)
  • Scientific creativity and driven to address fundamental biological questions

Send your application as one pdf file by email to hannes.linkspam prevention@uni-tuebingen.de by February 15, 2022. The pdf file should contain: a cover letter, your CV and certificates.

The university advocates equal rights for all genders and therefore urges women and gender-diverse people to apply. Equally qualified applicants with disabilities will be given preference.

The hiring process is carried out by the central administration of the university.

 

Biologisch-technische/r Assistent/in (BTA) für Massenspektrometrie

In der Arbeitsgruppe Bacterial Metabolomics ist zum 01.06.2022 eine Stelle als

Biologisch-technische/r Assistent/in (BTA) für Massenspektrometrie (w/m/d, E 9a TV-L, 100%)

befristet bis 31.03.2026 zu besetzen.

Die Forschungsgruppe „Bacterial Metabolomics“ unter der Leitung von Prof. Dr. Hannes Link sucht eine/n Biologisch-technische/r Assistent/in (BTA) für die Betreuung und Organisation unserer Metabolomics-Plattform. Unsere Gruppe entwickelt neuartige Metabolomics-Methoden mit Anwendungen in verschiedenen Forschungsbereichen wie z.B. der Mikrobiom-Forschung und dem Metabolic Engineering. Weitere Informationen über unsere Gruppe finden Sie unter https://www.linkmetabolism.com.

Ihre Aufgaben

  • Metabolom-Analysen: Durchführung und Betreuung von Metabolom-Studien mit Massen-spektrometrie gekoppelt an Flüssigchromatographie (LC-MS/MS).
  • Organisation der Massenspektrometrie und der Flüssigchromatographie: Wartung und Kalibrierung der Massenspektrometer, Wartung und Überprüfung der Flüssigchromatographie und der Probengeber, Koordination des Material- und Chemikalienbedarfs, Herstellen von LC-MS Laufmitteln, Einweisen und Anleiten von Studierenden in das Arbeiten mit Massenspekt-rometern.
  • Betreuung von Arbeitsabläufen: Erstellen von Betriebsanweisungen und standardisierten Arbeitsabläufen für die Massenspektrometrie und die Flüssigkeitschromatographie, Verwal-tung und Organisation der Nutzung der LC-MS Systeme.
  • Probenahmen: Erstellen von Betriebsanweisungen und standardisierten Arbeitsabläufen für die Probennahme und Extraktion von Metaboliten aus Bakterien (S1 und S2 Organismen).

Unsere Anforderungen

  • Abgeschlossene Berufsausbildung als Biologisch-technische/r Assistent/in (m/w/d).
  • Gute Kenntnisse und praktische Erfahrungen mit analytischen Arbeitstechniken (Flüssigkeitschromatographie und Massenspektrometrie), sowie mikrobiologischen Arbeiten.
  • Sehr gute Kenntnisse in biologischer Sicherheit und Erfahrung im Umgang mit infektiösen Organismen der Sicherheitsstufe 2.
  • Erfahrungen in der Labororganisation und Betreuung von Laborgeräten.
  • Interesse am experimentellen Arbeiten und an analytischen Fragestellungen.
  • Fundierte Kenntnisse in der Massenspektrometrie.
  • Kenntnisse in MS-Office und Excel.
  • Teamfähigkeit, verantwortungsbewusstes und zuverlässiges Arbeiten.

Schwerbehinderte werden bei gleicher Eignung bevorzugt berücksichtigt. Frauen werden ausdrücklich zur Bewerbung aufgefordert. Die Stelle ist grundsätzlich teilbar.

Bewerbungen sind mit Anschreiben, Lebenslauf und Zeugnissen zusammengefasst in einer PDF-Datei bis 15.02.2022 per E-Mail an hannes.linkspam prevention@uni-tuebingen.de zu richten.
Die Einstellung erfolgt durch die Zentrale Verwaltung.

 

PhD Student (EN)

At the Department of Dermatology, University Hospital Tübingen, in the working group of Prof. Dr. rer. nat. Birgit Schittek - Natural Immunity of the Skin -, the position of a

PhD student (E13 65%)

Is to be filled as soon as possible, latest April 1, 2022.

 

The position is initially limited until October 2024 with the option to extend.

The scientific focus is a CMFI funded project to investigate the regulation of Staphylococcus aureus - mediated skin inflammation by pathogen- and host-derived lipid membranes and the influence of the microbiome on S. aureus skin colonization. There is a close cooperation with the Interfaculty Institute for Microbiology and Infection Medicine Tübingen (IMIT).

The tasks of the PhD student include the implementation of a wide variety of methods: microbiological methods (e.g. antimicrobial tests, creation of different bacterial cultures), biochemical methods (e.g. HPLC, lipid / lipoprotein purification, SDS-PAGE, Western blot, chromatography), immunological methods (immunofluorescence, immunoprecipitation, ELISA , FACS) and cell biological methods (e.g. cell culture, 3D skin model, transfections, proliferation tests, apoptosis assays), mouse infection experiments.

Applicants should be reliable and able to work in a team and have good practical experience in cell biological, immunological and infectious research skills and with the methods mentioned above. Experience in cell culture and animal experiments is an advantage. In addition, we expect the results to be documented on the computer with the Windows programs Word, Excel, Power Point, GraphPad Prism.

Please send your written application by e-mail by January 30, 2022 at the latest to: birgit.schittekspam prevention@uni-tuebingen.de.

 

Postdoctoral Researcher (EN)

Postdoc position (E13 TV-L, 100%) – Interactions between infected macrophages and endothelial cells under shear fluid flow on an endothelium-on-chip device

to be filled assoon as possible. The position is initially limited to three years.


The Bastounis lab at the Interfaculty Institute of Microbiology & Infection Medicine and the Loskill lab at the Institute of Biomedical Engineering at the University of Tübingen are looking to fill one Postdoctoral position (E13 TV-L, 100%) as part of a collaborative research project funded by the Cluster of Excellence “Controlling Microbes to Fight Infections” (CMFI).
The earliest starting date for this position will be on 01.02.2022. The position is funded for a period of three years. The available position focuses on deciphering the interactions between endothelia and bacterially-infected macrophages in an endothelium-on-chip device.

Specific research project
One way that intracellular bacterial pathogens like L. monocytogenes spread systemically in vivo is by being carried from tissue to tissue within immune cells. Thus, it is critical to understand how infected immune cells transfer pathogens into endothelial cells or transmigrate
through them. By co-culturing endothelial cells with infected macrophages in an endothelium-on-chip device that allows exposing cells to (patho)physiological shear fluid flow, we aim to explore the roles (1) of the mechanics of “donor macrophage” versus “recipient endothelial
cell” during heterotypic bacterial transfer and (2) of the tensional forces of endothelial cells (that can be thought of as a proxy of the endothelial cell barrier integrity) in regulating infected-macrophage transmigration though the endothelium.

Candidate profile
The ideal candidate preferably brings along a degree that demonstrates an interdisciplinary background in both life and engineering sciences. While a background in host-pathogen interactions, cell biology, microscopy is a plus, a solid background in basic computer programming (e.g., MATLAB, Python etc.), image processing as well as microfluidics and microfabrication is also important to carry out the planned studies and analysis. We are looking for a highly motivated candidate with excellent communication and initiative skills, who is excited to conduct interdisciplinary studies and can team up with the various scientists in the Bastounis lab (https://www.bastounislab.org) and in the Loskill lab (http://www.loskill-lab.com).

We offer work environment that is strongly stimulating with state-of-the-art infrastructure and various facilities (check the IMIT, CMFI and NMI websites) which will provide the successful applicant with unique opportunities to develop a strong interdisciplinary portfolio in microbiology,
microscopy, cell biology, biomechanics and bioengineering.

For further information about the position, please contact Dr Peter Loskill and Dr Effie Bastounis by e-mail at peter.loskillspam prevention@uni-tuebingen.de and effie.bastounisspam prevention@uni-tuebingen.de.

Applications with a short cover/motivation letter, CV/biosketch, diploma(s) and two contacts for references should be sent via email to both principal investigators.

The University aims to increase the proportion of women in research and teaching and urges suitably qualified women scientists to apply. Qualified international researchers are expressly invited to apply. Disabled persons with equal aptitude will be given preferential consideration.

PhD Student (EN)

PhD position (E13 TV-L, 65%) – Host-pathogen interactions and cell biomechanics


to be filled as soon as possible. The position is initially limited to three years.

The Cluster of Excellence “Controlling Microbes to Fight Infections” (CMFI) and the Interfaculty Institute of Microbiology & Infection Medicine (IMIT) at the University of Tübingen are looking to fill one PhD position (E13 TV-L, 65%) as part of Junior Group Leader Dr. Effie Bastounis’ research group. The earliest starting date for this position will be on 01.02.2022. The position is funded for a period of 3 years at least. The available position focuses on exploring the role of intra- and extra-cellular physical forces in driving intracellular bacterial spread through infected epithelia.


Specific research project
During infection with the food-borne intracellular bacterial pathogen L. monocytogenes, large infected domains in epithelial cell monolayers are forced to extrude to form 3D mounds due to the collective and cooperative onslaught triggered by their uninfected neighbors. This mechanical competition between uninfected and bacterially-infected cells is driven by innate immunity signals and appears to limit pathogen dissemination through the epithelium (Bastounis et al 2021). The project seeks to investigate how signaling and cytoskeletal dynamics correlate with changes in host cell mechanics during intracellular bacterial spread through epithelial monolayers. We also want to understand the contribution of extracellular mechanical cues (extracellular matrix stiffness) in promoting or obstructing this biomechanical battle in favor of the host.


Candidate profile
The ideal candidate preferably brings along a degree that demonstrates an interdisciplinary background in both life and engineering sciences. While a background in host-pathogen interactions, cell biology, microscopy is a plus, a solid background in basic computer programming (e.g. MATLAB, Python etc.) and/or image processing is also important to carry out the planned studies and analysis. We are looking for a highly motivated candidate with excellent communication and initiative skills, who is excited to conduct interdisciplinary studies and can team up with the various scientists with whom we are collaborating. We offer work environment that is strongly stimulating with state-of-the-art infrastructure and various facilities (check the IMIT and CMFI websites) which will provide the successful applicant with unique
opportunities to develop a strong interdisciplinary portfolio in microbiology, microscopy, cell biology and biomechanics.

For further information about the position, please contact Effie Bastounis by e-mail at effie.bastounisspam prevention@uni-tuebingen.de, and visit our website https://www.bastounislab.org.

Applications with a short cover/motivation letter, CV/biosketch, diploma(s) and two contacts for references should be sent via email to effie.bastounisspam prevention@uni-tuebingen.de.

The University aims to increase the proportion of women in research and teaching and urges suitably qualified women scientists to apply. Qualified international researchers are expressly invited to apply. Disabled persons with equal aptitude will be given preferential consideration.

 

PhD Student (EN)

PhD position (E13 TV-L, 65%) – Intestinal cell biomechanics during bacterial infection


to be filled as soon as possible. The position is initially limited to three years.

The Bastounis lab at the Interfaculty Institute of Microbiology & Infection Medicine/Cluster of Excellence “Controlling Microbes to Fight Infections” (CMFI) at the University of Tübingen is looking to fill one PhD position (E13 TV-L, 65%) as part of a DFG funded project in collaboration with the Constantinou lab at TU Braunschweig. The earliest starting date for this position will be on 01.03.2022. The position is funded for a period of three years. The available position focuses on deciphering host-pathogen interactions using an organotypic stretching device and biomechanical approaches.

Specific research project
During infection with the food-borne intracellular bacterial pathogen L. monocytogenes, large infected domains in epithelial cell monolayers are forced to extrude to form 3D mounds due to the collective and cooperative onslaught triggered by their uninfected neighbors. This mechanical competition between uninfected and bacterially-infected cells is driven by innate immunity signals and appears to limit pathogen dissemination through the epithelium (Bastounis et al 2021). The project seeks to investigate how biochemical and physical cues in concert orchestrate intracellular bacterial dissemination in epithelial cells in monolayer in a multifunctional cell stretching platform, that will allow us to mimic peristalsis-like cellular stretching, similar to what epithelial cells are experiencing in the intestine.

Candidate profile
The ideal candidate preferably brings along a degree that demonstrates an interdisciplinary background in both life and engineering sciences. While a background in host-pathogen interactions,
cell biology, microscopy is a plus, a solid background in basic computer programming (e.g. MATLAB, Python etc.) and/or image processing is also important to carry out the planned studies and analysis. We are looking for a highly motivated candidate with excellent communication and initiative skills, who is excited to conduct interdisciplinary studies and can team up with the various scientists with whom we are collaborating and particularly with the Constantinou lab at TU Braunschweig who will develop the multifunctional cell stretching platform (https://www.tu-braunschweig.de/imt/institut/team/iordania-constantinou).
We offer work environment that is strongly stimulating with state-of-the-art infrastructure and various facilities (check the IMIT and CMFI websites) which will provide the successful applicant with unique opportunities to develop a strong interdisciplinary portfolio in microbiology, microscopy, cell biology and biomechanics.

For further information about the position, please contact Effie Bastounis by e-mail at effie.bastounisspam prevention@uni-tuebingen.de, and visit our website https://www.bastounislab.org.

Applications with a short cover/motivation letter, CV/biosketch, diploma(s) and two contacts for references should be sent via email to effie.bastounisspam prevention@uni-tuebingen.de.

The University of Tübingen aims to increase the proportion of women in research and teaching and urges suitably qualified women scientists to apply. Qualified international researchers are expressly invited to apply. Disabled persons with equal aptitude will be given preferential consideration.

 

Postdoctoral Researcher (EN)

The Functional Metabolomics Lab, part of the Cluster of Excellence “Controlling Microbes to Fight Infections” (CMFI) at the University of Tübingen, aims to understand and control microbial communities in order to contribute to the fight against infections. The group uses a multidisciplinary approach at the interface of natural product research, mass spectrometry-based metabolomics, and proteomics as well as chemical biology (www.functional-metabolomics.com).

For a project in the Collaborative Research Center CellMap (https://trr261.de), we are looking for a:

Postdoctoral Researcher (f/m/d)

to work on the application of native mass spectrometry and metabolomics approaches to study ClpP protease regulation mechanisms and the screening for new inhibitors.

For the position, we offer salary according to TV-L, E13 (100%). Besides inclusive environment, supportive mentoring and guidance for your individual career development, we provide detailed scientific training and access to state-of- the-art equipment and open science communication. Beyond scientific publications, this will include conference visits, organization and attendance of workshops and close collaborations with other research groups, including possible research visits at other universities.

As part of the CMFI Cluster of Excellence in Tübingen, you will be working in an excellent research environment with plenty of potential collaboration partners, a high amount of autonomy, and possibilities to develop and apply for funding for your own research ideas. The main focus of the position will be on research (no formal teaching duties); however, there will be the possibility to participate in college level teaching and mentoring of bachelor and master students.

At the time of employment, the candidate should have a PhD degree in analytical chemistry, biochemistry, biotechnology, or a related field. We expect that the candidate will be interested in highly interdisciplinary research; has an independent, responsible, and committed work attitude and is fluent in (scientific) English.

We expect strong knowledge of and interest to further develop bioanalytical techniques, in particular high-resolution mass spectrometry-based approaches.

Ideally, the candidate will bring experience in native mass spectrometry and protein biochemistry methods, such as heterologous protein expression and protein purification

Applications and inquiries should be sent to daniel.petrasspam prevention@uni-tuebingen.de.

Please send your application as a single PDF file that includes: a brief statement on your research interests and experience; your CV (including a list of publications); contact information for two academic references; and university transcripts.

The University of Tübingen is an Equal Opportunity Employer with a strong institutional commitment to excellence through diversity. All qualified applicants will be considered for employment without regards to gender, race, color, national origin, sexual orientation, religion, disability, or age.

PhD Student (EN)

 

 

The Functional Metabolomics Lab, part of the Cluster of Excellence “Controlling Microbes to Fight Infections” (CMFI) at the University of Tübingen, aims to understand and control microbial communities in order to contribute to the fight against infections. The group uses a multidisciplinary approach at the interface of natural product research, mass spectrometry-based metabolomics, and proteomics as well as chemical biology (www.functional-metabolomics.com).

The lab's science mission is to develop and apply mass spectrometry-based tools to systematically determine the role of small molecules in complex microbial communities and to mine them for novel bioactive compounds. For the development and application of native mass spectrometry and bioactivity guided metabolomics methods we are looking for a:

PhD Student (f/m/d)

The project will focus on the method development and application of native MS, HPLC fractionation, and bioactivity-guided approaches in combination with non-targeted metabolomics for the screening of culture extracts and environmental samples.

For the position, we offer salary according to TV-L, E13 (65%). Besides supportive mentoring and guidance for your individual career development, we provide detailed scientific training on state-of-the-art equipment and open, community-focused science communication. Beyond scientific publications, this will include conference visits, organization and attendance of workshops and possible research visits to other universities and field sites.

As part of the Cluster of Excellence CMFI in Tübingen you will be located in an excellent research environment with plenty of potential collaboration partners, a high amount of autonomy, and possibilities to develop your own research ideas.

At the time of employment, the candidate should have a masters or equivalent degree in chemistry, biochemistry, biotechnology, or a related field. We expect that the candidate is interested in highly interdisciplinary research, has an independent, responsible and committed work attitude, and is fluent in (scientific) English.

We expect good knowledge of bioanalytical techniques, in particular mass spectrometry as well as biochemistry and/or microbiology.

Ideally, the candidate will bring basic statistical and computational skills (e.g., scripting in Python, R, or MATLAB) and an interest to learn computational methods for mass spectrometry data analysis.

Applications or questions about the position should be sent to daniel.petrasspam prevention@uni-tuebingen.de.

Please send your application as a single PDF file that includes: a brief statement on your interests and experience; your CV; contact information for two academic references; and university transcripts.

The University of Tübingen is an Equal Opportunity Employer with a strong institutional commitment to excellence through diversity. All qualified applicants will be considered for employment without regard to gender, race, color, national origin, sexual orientation, religion, disability, or age.

The review of applications will begin in August 2021 and will continue until the position is filled.

 

Postdoctoral Researcher (EN)

 

The Functional Metabolomics Lab, part of the Cluster of Excellence “Controlling Microbes to Fight Infections” (CMFI) at the University of Tübingen, aims to understand and control microbial communities in order to contribute to the fight against infections. The group uses a multidisciplinary approach at the interface of natural product research, mass spectrometry-based metabolomics, and proteomics as well as chemical biology (www.functional-metabolomics.com).

The lab's science mission is to develop and apply mass spectrometry-based tools to systematically determine the role of small molecules in complex microbial communities and to mine them for novel bioactive compounds. To build up the mass spectrometry pipeline, we are looking for a:

Postdoctoral Researcher (f/m/d)

to work on method development and application of tandem MS and native MS approaches for the analysis of culture extracts and environmental samples, as well as the bioinformatic data analysis.

For the position, we offer salary according to TV-L, E13 (100%). Besides supportive mentoring and guidance for your individual career development, we provide detailed training and access to state-of- the-art equipment and open, community-focused science communication. Beyond scientific publications, this will include conference visits, organization and attendance of workshops and possible research visits to other universities and field sites.

As part of the Cluster of Excellence CMFI in Tübingen, you will be working in an excellent research environment with plenty of potential collaboration partners, a high amount of autonomy, and possibilities to develop and apply for funding for your own research ideas. The main focus of the position will be on research (no formal teaching duties); however, there will be the possibility to participate in college level teaching and mentoring of bachelor and master students.

At the time of employment, the candidate should have a PhD degree in analytical chemistry, biochemistry, biotechnology, or a related field. We expect that the candidate will be interested in highly interdisciplinary research; has an independent, responsible, and committed work attitude and is  fluent in (scientific) English.

We expect strong knowledge of and interest to develop bioanalytical techniques, in particular high- resolution mass spectrometry-based approaches (such as metabolomics, proteomics, or structure elucidation).

Ideally, the candidate will bring fundamental statistical and computational skills (e.g., scripting in Python, R, or MATLAB) and an interest to broaden their use of computational methods for mass spectrometry data analysis.

Applications and inquiries should be sent to daniel.petrasspam prevention@uni-tuebingen.de.

Please send your application as a single PDF file that includes: a brief statement on your interests and experience; your CV (including a list of publications); contact information for two academic references; and university transcripts.

The University of Tübingen is an Equal Opportunity Employer with a strong institutional commitment to excellence through diversity. All qualified applicants will be considered for employment without regard to gender, race, color, national origin, sexual orientation, religion, disability, or age.

The review of applications will begin in August 2021 and will continue until the position is filled.

Postdoctoral researchers in Mathematical and Computational Population Genetics (EN)

 

The newly founded independent junior research group „Mathematical and Computational Population Genetics“, headed by Franz Baumdicker at the University of Tübingen has an opening for

Postdoctoral researchers (f/m/d)

The group develops and applies mathematical models and bioinformatic tools with a special focus on microbial evolution. We are interested in a variety of evolutionary scenarios including CRISPR Cas Evolution, Pan-Genome Evolution, Horizontal Gene Transfer, Fluctuationg Selection, and Cooperation in Bacteria.

The postdoc should be interested to operate at the intersection of Mathematical Population Genetics / Computational Biology / Bioinformatics using mathematical population genetics, phylogenetics, statistical analysis, machine learning algorithms, and large scale simulations to derive new mathematical results, develop open source software and apply them to (microbial) genome data.

For scientific questions please contact: franz.baumdicker@uni-tuebingen.de.

 

Candidate profiles we would love to see:

  • PhD degree in (Bio-)Mathematics, Statistics, Bioinformatics, Computational Biology or a related field
  • Interest in interdisciplinary research
  • Strong mathematical preparation and interest and/or good computational skills (e.g. in Python, R)
  • Independent, responsible and committed work
  • Fluency in (scientific) English

 

What we offer:

  • Salary according to TV-L, E13 (100%)
  • The group is part of two Excellence Clusters (Controlling Microbes to Fight Infections & Machine Learning) in Tübingen, which offers an excellent research environment with plenty of potential collaboration partners.
  • Flexible starting date and the possibility to start the project remotely in the initial phase
  • Focus on research (no formal teaching duties)
  • Intense personal and scientific mentoring in an open and supportive environment
  • Integration into a young and agile research group
  • Responsibility to conduct your own research projects with a high amount of autonomy
  • The opportunity to visit and organize conferences, workshops and research visits to other universities and summer schools.
  • Possibilities to develop your own research ideas and mentor Ph.D. students

 

The University of Tübingen is an Equal Opportunity Employer with a strong institutional commitment to excellence through diversity. All qualified applicants will be considered for employment without regard to gender, race, color, national origin, sexual orientation, religion, disability, or age. Researchers from outside Germany are particularly encouraged to apply.

Applications and inquiries should be sent to franz.baumdickerspam prevention@uni-tuebingen.de.

Please send your application as a single PDF file and include a brief statement on your interests and experience, CV (including a possible list of publications and the contact info of two academic references), and university transcripts.

The review of applications will begin in July 2021 and continue until the positions are filled.

PhD students in Mathematical and Computational Population Genetics (EN)

 

The newly founded independent junior research group „Mathematical and Computational Population Genetics“ headed by Franz Baumdicker at the University of Tübingen has an opening for

PhD students (f/m/d)

The group develops and applies mathematical models and bioinformatic tools with a special focus on microbial evolution.

The PhD students will work at the intersection of Mathematical Population Genetics / Computational Biology / Bioinformatics using population genetics, phylogenetics, statistical analysis, machine learning algorithms, and large scale simulations to derive new theoretical results, develop open source software and apply them to (microbial) genome data.

We are interested in a variety of evolutionary scenarios including CRISPR-Cas Evolution and Dynamics, Pan-Genome Evolution, Horizontal Gene Transfer, Fluctuationg Selection, and Cooperation in Bacteria.

For scientific questions please contact: franz.baumdicker@uni-tuebingen.de.


Candidate profiles we would love to see:

  • Master's degree in (Bio-)Mathematics, Statistics, Bioinformatics, Computational Biology or a related field
  • Interest in interdisciplinary research
  • Strong mathematical preparation and interest and/or good computational skills (e.g. in Python, R)
  • Independent, responsible and committed work
  • Fluency in (scientific) English


What we offer:

  • Salary according to TV-L, E13 (65%)
  • Dissertation at the Faculty of Natural Sciences working with two advisors
  • The group is part of two Excellence Clusters (Controlling Microbes to Fight Infections & Machine Learning) in Tübingen, which offers an excellent research environment with plenty of potential collaboration partners.
  • Possibly integration into the DFG priority programme SPP2141, where appropriate
  • Focus on research (no formal teaching duties)
  • Intense personal and scientific mentoring in an open and supportive environment
  • Integration into a young and agile research group
  • The opportunity to visit conferences, workshops, other research groups and summer schools.
  • Responsibility to conduct your own research projects with a high amount of autonomy
  • Possibilities to develop your own research ideas in a young and agile team


The University of Tübingen is an Equal Opportunity Employer with a strong institutional commitment to excellence through diversity. All qualified applicants will be considered for employment without regard to gender, race, color, national origin, sexual orientation, religion, disability, or age. Researchers from outside Germany are particularly encouraged to apply.

Applications and inquiries should be sent to franz.baumdickerspam prevention@uni-tuebingen.de.

Please send your application as a single PDF file and include- brief statement on the applicant's interests and experience, CV (including a possible list of publications and the contact info of two academic references), and university transcripts.

The review of applications will begin in July 2021 and continue until the positions are filled.