Interfakultäres Institut für Mikrobiologie und Infektionsmedizin

Publikationen und Förderung


Publications in Peer-Reviewed Journals
 

1. Heilbronner S* and Foster TJ. Staphylococcus lugdunensis. A skin commensal with invasive pathogenic potential. Clin Microbiol Rev 34(2). (2021) *Corresponding author

2. Krauss S, Zipperer A, Wirtz S, Saur J, Konnerth M, Heilbronner S, Torres Salazar B, Grond S, Krismer B, Peschel A. Secretion of and immunity to the novel fibupeptide antimicrobial lugdunin by distinct ABC transporters in Staphylococcus lugdunensis. Antimicrob Agents Chemother  65(1). (2020)

3. Belikova D, Jochim A, Power J, Holden MT, Heilbronner S. Gene accordions cause genotypic and phenotypic heterogeneity in clonal populations of Staphylococcus aureus. Nat Commun 11, 3526. (2020)

4. Jochim A, Adolf L, Belikova D, Schilling NA, Setyawati I, Chin D, Meyers S, Verhamme P, Heinrichs DE, Slotboom DJ, Heilbronner S. An ECF-type transporter scavenges heme to overcome iron-limitation in Staphylococcus lugdunensis. Elife 9 (2020)

5. Jochim A, Shi T, Belikova D, Schwarz S, Peschel A, Heilbronner S. Methionine Limitation Impairs Pathogen Expansion and Biofilm Formation Capacity. Appl Environ Microbiol 85. (2019)

6. Heilbronner S. Commentary: Staphylococcus aureus Membrane-Derived Vesicles Promote Bacterial Virulence and Confer Protective Immunity in Murine Infection Models. Front Microbiol 9:2346. (2018)

7. Heilbronner S, Monk IR, Brozyna JR, Heinrichs DE, Skaar EP, Peschel A, Foster TJ. Competing for Iron: Duplication and Amplification of the isd Locus in Staphylococcus lugdunensis HKU09-01 Provides a Competitive Advantage to Overcome Nutritional Limitation. PLoS Genet 12(8):e1006246. (2016)

8. Liesenborghs L, Peetermans M, Claes J, Veloso TR, Vandenbriele C, Criel M, Lox M, Peetermans WE, Heilbronner S, de Groot PG, Vanassche T, Hoylaerts MF, Verhamme P. Shear-Resistant Binding to von Willebrand Factor Allows Staphylococcus lugdunensis to Adhere to the Cardiac Valves and Initiate Endocarditis. J Infect Dis 213(7):1148-1156. (2016).

9. Ernst CM, Kuhn S, Slavetinsky CJ, Krismer B, Heilbronner S, Gekeler C, Kraus D, Wagner S, Peschel A. The lipid-modifying multiple peptide resistance factor is an oligomer consisting of distinct interacting synthase and flippase subunits. MBio 6(1). (2015).

10. Farrand AJ, Haley KP, Lareau NM, Heilbronner S, McLean JA, Foster T, Skaar EP. An Iron-Regulated Autolysin Remodels the Cell Wall To Facilitate Heme Acquisition in Staphylococcus lugdunensis. Infect Immun 83(9):3578-3589. (2015)

11. Missineo A, Di Poto A, Geoghegan JA, Rindi S, Heilbronner S, Gianotti, V, Arciola CR, Foster TJ, Speziale P, Pietrocola G. IsdC from Staphylococcus lugdunensis Induces Biofilm Formation under Low-Iron Growth Conditions. Infect Immun 82(6): 2448-2459. (2014)

12. Heilbronner S, Hanses F, Monk IR, Speziale P, Foster TJ. Sortase A Promotes Virulence in Experimental Staphylococcus lugdunensis Endocarditis. Microbiology 159(Pt 10): 2141-2152. (2013)

13. Heilbronner S, Monk IR, Foster TJ. The phage integrase vector pIPI03 allows RecA-independent, site-specific labelling of Staphylococcus lugdunensis strains. Plasmid 70, 377-384. (2013)

14. Zapotoczna M, Heilbronner S, Speziale P, Foster TJ. Iron-Regulated Surface Determinant (Isd) Proteins of Staphylococcus lugdunensis. J Bacteriol 194, 6453-6467. (2012)

15. Haley KP, Janson EM, Heilbronner S, Foster TJ & Skaar EP. Staphylococcus lugdunensis IsdG Liberates Iron from Host Heme. J Bacteriol 193, 4749-4757. (2011)

16. Heilbronner S, Holden MT, van Tonder A, Geoghegan JA, Foster TJ, Parkhill J, Bentley SD. Genome sequence of Staphylococcus lugdunensis N920143 allows identification of putative colonization and virulence factors. FEMS Microbiol Lett 322, 60-67. (2011)

 

Funding
  • Deutsches Zentrum für Infektionsforschung (DZIF) – TTU HAARBI
  • European Commission for Research and Innovation – Gen Duplication and Amplification in Staphylococcal Populations. Individual Marie-Curie fellowship (2015-2017)
  • Ministerium für Wissenschaft, Forschung und Kunst Baden-Württemberg - RiSC-Program - Detection and Effects Of Gene Amplification In Staphylococcal Clonal Populations (2018-2019)
  • DFG – HE8381 - An ECF-type transporter scavenges heme to overcome iron-limitation in Staphylococcus lugdunensis
  • DFG – TRR261 – Cellular Mechanism of Antibiotic Action and Production – Project B04
    (https://uni-tuebingen.de/forschung/forschungsschwerpunkte/sfb-transregios/sfb-trr-antibiotic-cellmap/)
  • Cluster of Excellence - Controlling Microbes to Fight Infection
    (https://uni-tuebingen.de/en/research/core-research/cluster-of-excellence-cmfi/cmfi/)