28.07.2017

How protein interactions drive cellular death

The Garcia group proposes a novel integrative model for how Bcl-2 proteins regulate apoptosis in their new article in Nature Communications.

For further information on this study, see

<link https: www.uni-tuebingen.de uploads media external-link-new-window external link in new>Press Release (English)

<link https: www.uni-tuebingen.de uploads media external-link-new-window external link in new>Pressemitteilung (Deutsch)

Original Publication:

Stephanie Bleicken, Annika Hantusch, Kushal Kumar Das, Tancred Frickey, Ana J. Garcia-Saez: Quantitative interactome of a membrane Bcl-2 network identifies a hierarchy of complexes for apoptosis regulation, in: Nature Communications, 2017, DOI: 10.1038/s41467-017-00086-6

Link to open access: <link http: rdcu.be t94m external-link-new-window external link in new>here

Contact:

Dr. Stephanie Bleicken
Electron Paramagnetic Resonance Spectroscopy Group and Zemos
Faculty of Chemistry and Biochemistry
Ruhr-Universität Bochum, Germany
Phone: +49 234 32 21891
Email: <link mail window for sending>stephanie.bleicken[at]rub.de

Prof. Dr. Ana J. García-Sáez
Interfaculty Institute of Biochemistry
University of Tübingen, Germany
Phone: +49 7071 29 73318
Email: <link mail external link in new>ana.garcia[at]uni-tuebingen.de