Lorenz Dörner, Lucia Grosse, Felix Stange, Hanni Hille, Sylvia Kurz, Hannes Becker, Sebastian Volkmer, Melina Hippler, David Rieger, Paula Bombach, Johannes Rieger, Lina Weinert, Laura Svensson, Carolin Anders, Sila Cekin, Frank Paulsen, Öznur Öner, Kristina Ruhm, Holly Sundberg Malek, Yonne Möller, Marcos Tatagiba, Markus Wallwiener, Nils Eckert, Pascal Escher, Nico Pfeifer, Andrea Forschner, Armin Bauer, Daniel Zips , Michael Bitzer, Nisar Malek, Cihan Gani, Ghazaleh Tabatabai, Mirjam Renovanz App-based assessment of patient-reported outcomes in the Molecular Tumor Board in the Center for Personalized Medicine—(TRACE) Neuro-Oncology Practice XX(XX), 1–11, 2024
Pontus Hedberg, Milosz Parczewski, Karol Serwin, Giulia Marchetti, Francesca Bai, Björn-Erik Ole Jensen, Joana P.V. Pereira, Francis Drobniewski, Henrik Reschreiter, Daniel Naumovas, Francesca Ceccherini-Silberstein, Gibran Horemheb Rubio Quintanares, Matilu Mwau, Cristina Toscano, Florian König, Nico Pfeifer, Maurizio Zazzi, Iuri Fanti, Francesca Incardona, Alessandro Cozzi-Lepri, Anders Sönnerborg, Pontus Nauclér In-hospital mortality during the wild-type, alpha, delta, and omicron SARS-CoV-2 waves: a multinational cohort study in the EuCARE project The Lancet Regional Health - Europe 2024, 100855, ISSN 2666-7762
P. Schommers, D.S. Kim, M. Schlotz, C. Kreer, R. Eggeling, A. Hake, M. Stecher, J. Park, C.E. Radford, A.S. Dingens, M.S. Ercanoglu, H. Gruell, S. Odidika, M. Dahlhaus, L. Gieselmann, E. Ahmadov, R.Y. Lawong, E. Heger, E. Knops, C. Wyen, T. Kümmerle, K. Römer, S. Scholten, T. Wolf, C. Stephan, I. Suárez, N. Raju, A. Adhikari, S. Esser, H. Streeck, R. Duerr, A.J. Nanfack, S. Zolla-Pazner, C. Geldmacher, O. Geisenberger, A. Kroidl, W. William, L. Maganga, N.E. Ntinginya, I.S. Georgiev, J.J. Vehreschild, M. Hoelscher, G. Fätkenheuer, J.J. Lavinder, J.D. Bloom, M.S. Seaman, C. Lehmann, N. Pfeifer, G. Georgiou, F. Klein Dynamics and durability of HIV-1 neutralization are determined by viral replication Nature Medicine 2023
Maarten A. A. van de Klundert, Anastasiia Antonova, Giulia Di Teodoro, Rafael Ceña Diez, Nikoloz Chkhartishvili, Eva Heger, Anna Kuznetsova, Aleksey Lebedev, Aswathy Narayanan, Ekaterina Ozhmegova, Alexander Pronin, Andrey Shemshura, Alexandr Tumanov, Nico Pfeifer, Rolf Kaiser, Francesco Saladini, Maurizio Zazzi, Francesca Incardona, Marina Bobkova, Anders Sönnerborg Molecular Epidemiology of HIV-1 in Eastern Europe and Russia Viruses 2022, 14, 2099
Gibran Horemheb Rubio*, Ralf Eggeling*, Norbert Schmeiβer, Nico Pfeifer, Thomas Lengauer, Barbara C. Gärtner, Christiane Prifert, Matthias Kochanek, Christoph Scheid, Ortwin Adams, Rolf Kaiser*, Respiratory Virus Network Respiratory viruses dynamics and interactions: ten years of surveillance in central Europe BMC Public Health, 2022, 1167 *: equal contribution
Marius Lange, Volker Bergen, Michal Klein, Manu Setty, Bernhard Reuter, Mostafa Bakhti, Heiko Lickert, Meshal Ansari, Janine Schniering, Herbert B. Schiller, Dana Pe’er, Fabian J. Theis CellRank for directed single-cell fate mapping Nature Methods, 2022
Timm Weber, Julian Potthoff, Sven Bizu, Maurice Labuhn, Leona Dold, Till Schoofs, Marcel Horning, Meryem S. Ercanoglu, Christoph Kreer, Lutz Gieselmann, Kanika Vanshylla, Bettina Langhans, Hanna Janicki, Luisa J. Ströh, Elena Knops, Dirk Nierhoff, Ulrich Spengler, Rolf Kaiser, Pamela J. Bjorkman, Thomas Krey, Dorothea Bankwitz, Nico Pfeifer, Thomas Pietschmann, Andrew I. Flyak, Florian Klein Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization Immunity, 2022
David Blumenthal, Julian Matschinske, Nicolas Alcaraz, Arriel Benis, Martin Golebiewski, Dominik Grimm, Lukas Heumos, Tim Kacprowski, Olga Lazareva, Markus List, Zakaria Louadi, Josch Pauling, Nico Pfeifer, Richard Röttger, Veit Schwämmle, Gregor Sturm, Alberto Traverso, Kristel Van Steen, Martiela Freitas, Gerda Villalba Silva, Leonard Wee, Nina Wenke, Massimiliano Zanin, Olga Zolotareva, Jan Baumbach The AIMe registry for artificial intelligence in biomedical research Nature Methods, 2021
Kanika Vanshylla, Veronica Di Cristanziano, Franziska Kleipass, Felix Dewald, Philipp Schommers, Lutz Gieselmann, Henning Gruell, Maike Schlotz, Meryem S. Ercanoglu, Ricarda Stumpf, Petra Mayer, Matthias Zehner, Eva Heger, Wibke Johannis, Carola Horn, Isabelle Suárez, Norma Jung, Susanne Salomon, Kirsten Alexandra Eberhardt, Birgit Gathof, Gerd Fätkenheuer, Nico Pfeifer, Ralf Eggeling, Max Augustin, Clara Lehmann, Florian Klein Kinetics and correlates of the neutralizing antibody response to SARS-CoV-2 infectionin humans Cell Host and Microbe May 2021
C. Kreer, M. Zehner ,T. Weber, M. S. Ercanoglu, L. Gieselmann, C. Rohde, S. Halwe, M. Korenkov, P. Schommers, K. Vanshylla, V. Di Cristanziano, H. Janicki, R. Brinker, A. Ashurov, V. Krähling, A. Kupke, H. Cohen-Dvashi, M. Koch, J. M. Eckert, S. Lederer, N. Pfeifer, T. Wolf, M. J.G.T. Vehreschild, C. Wendtner, R. Diskin, H. Gruell, S. Becker, and F. Klein Longitudinal isolation of potent near-germline SARS-CoV-2-neutralizing antibodies from COVID-19 patients Cell 2020, 182(6):1663-1673
S. Ehrhardt, M. Zehner, V. Krähling, H. Cohen-Dvashi, C. Kreer, N. Elad, H. Gruell, M.S. Ercanoglu, P. Schommers, L. Grieselmann, R. Eggeling, C. Dahlke, T. Wolf, N. Pfeifer, M. Addo, R. Diskin, S. Becker, F. Klein Polyclonal and convergent antibody response to Ebola virus vaccine rVSV-ZEBOV Nature Medicine 2019, 25, 1589–1600
P. Mendoza, H. Gruell, L. Nogueira, J. Pai, A. Butler, K. Millard, C. Lehmann, I. Suárez, T. Oliveira, J. Lorenzi, Y. Cohen, C. Wyen, T. Kümmerle, T. Karagounis, C.-L. Lu, L. Handl, C. Unson-O’Brien, R. Patel, C. Ruping, M. Schlotz, M. Witmer-Pack, I. Shimeliovich, G. Kremer, E. Thomas, K. Seaton, J. Horowitz, A. West, P. Bjorkman, G. Tomaras, R. Gulick, N. Pfeifer, G. Fätkenheuer, M. Seaman, F. Klein, M. Caskey, M. C. Nussenzweig Combination therapy with anti-HIV-1 antibodies maintains viral suppression Nature 2018, 561, pp 479–484
Y. Bar-On, H. Gruell, T. Schoofs, J. Pai, L. Nogueira, A. Butler, K. Millard, C. Lehmann, I. Suárez, T. Oliveira, T. Karagounis, Y. Cohen, C. Wyen, S. Scholten, L. Handl, S. Belblidia, J. Dizon, J. Vehreschild, M. Pack, I. Shimeliovich, K. Jain, K. Fiddike, K. Seaton, N. Yates, J. Horowitz, R. Gulick, N. Pfeifer, G. Tomaras, M. Seaman, G. Fätkenheuer, M. Caskey, F. Klein, M. C. Nussenzweig Safety and antiviral activity of combination HIV-1 broadly neutralizing antibodies in viremic individuals Nature Medicine 2018
R. Apweiler, T. Beissbarth, M.R. Berthold, N. Blüthgen, Y. Burmeister, O. Dammann, A. Deutsch, F. Feuerhake, A. Franke, J. Hasenauer, S. Hoffmann, T. Höfer, P.L. Jansen, L. Kaderali, U. Klingmüller, I. Koch, O. Kohlbacher, L. Kuepfer, F. Lammert, D. Maier, N. Pfeifer, N. Radde, M. Rehm, I. Roeder, J. Saez-Rodriguez, U. Sax, B. Schmeck, A. Schuppert, B. Seilheimer, F.J. Theis, J. Vera, O. Wolkenhauer Whither systems medicine? Exp Mol Med. 2018 Mar 2;50(3):e453.
A. Pironti, N. Pfeifer, H. Walter, B.O. Jensen, M. Zazzi, P. Gomes, R. Kaiser, T. Lengauer Using drug exposure for predicting drug resistance – A data-driven genotypic interpretation tool PLoS One 2017, 12, e0174992
M. Caskey, T. Schoofs, H. Gruell, A. Settler, T. Karagounis, E. F. Kreider, B. Murrell, N. Pfeifer, L. Nogueira, T. Y. Oliveira, G. H. Learn, Y. Z. Cohen, C. Lehmann, D. Gillor, I. Shimeliovich, C. Unson-O’Brien, D. Weiland, A. Robles, T. Kümmerle, C. Wyen, R. Levin, M. Witmer-Pack, K. Eren, C. Ignacio, S. Kiss, A. P. West, Jr, H. Mouquet, B. S. Zingman, R. M. Gulick, T. Keler, P. J. Bjorkman, M. S. Seaman, B. H. Hahn, G. Fätkenheuer, S. J. Schlesinger, M. C. Nussenzweig, F. Klein Antibody 10-1074 suppresses viremia in HIV-1-infected individuals Nature Medicine 2017, 23, pp 185–191
J. F. Scheid*, Joshua A. Horwitz*, Y. Bar-On, E. F. Kreider, C.-L. Lu, J. C. C. Lorenzi, A. Feldmann, M. Braunschweig, L. Nogueira, T. Oliveira, I. Shimeliovich, R. Patel, L. Burke, Y. Z. Cohen, S. Hadrigan, A. Settler, M. Witmer-Pack, A. P. West, Jr., B. Juelg, T. Keler, T. Hawthorne, B. Zingman, R. M. Gulick, N. Pfeifer, G. H. Learn, M. S. Seaman, P. J. Bjorkman, F. Klein, S. J. Schlesinger, B. D. Walker, B. H. Hahn, M. C. Nussenzweig, and M. Caskey HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption Nature 2016, 535, pp 556–560 *: equal contribution
J. M. Carlson+, V. Y. Du*, N. Pfeifer*, A. Bansal, V. Y.F. Tan, K. Power, C. J. Brumme, A. Kreimer, C. E. DeZiel, N. Fusi, M. Schaefer, M. A. Brockman, J. Gilmour, M. A. Price, W. Kilembe, R. Haubrich, M. John, S. Mallal, R. Shapiro, J. Frater, P. R. Harrigan, T. Ndung’u, S. Allen, D. Heckerman, J. Sidney, T. M. Allen, P. J.R. Goulder, Z. L. Brumme, E. Hunter+, P. A. Goepfert+ Impact of Pre-adapted HIV Transmission Nature Medicine 2016, 22, pp 606-613 + These authors jointly supervised this work * These authors contributed equally to this work Free access via the Springer Nature sharing initiative: pdf Check out the video explaining the main findings: MSR webpage
T. Schoofs*, F. Klein*, M. Braunschweig*, K. F. Kreider, A. Feldmann, L. Nogueira, T. Oliveira, J. C. C. Lorenzi, E. H. Parrish, G. H. Learn, A. P. West, P. J. Bjorkman, S. J. Schlesinger, M. S. Seaman, J. Czartoski, M. J. McElrath, N. Pfeifer, B. H. Hahn, M. Caskey, and M. C. Nussenzweig HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1 Science 2016, 352 (6288), pp 997-1001 *: equal contribution
Y. Yagita, N. Kuse, K. Kuroki, H. Gatanaga, J. M. Carlson, T. Chikata, Z. L. Brumme, H. Murakoshi, T. Akahoshi, N. Pfeifer, S. Mallal, M. John, T. Ose, H. Matsubara, R. Kanda, Y. Fukunaga, K. Honda, Y. Kawashima, Y. Ariumi, S. Oka, K. Maenaka, M. Takiguchi Distinct HIV-1 Escape Patterns Selected by CTLs with Identical Epitope Specificity J. Virol. 2013, 87 (4), pp 2253-2263
O. Kohlbacher, K. Reinert, C. Gröpl, E. Lange, N. Pfeifer, O. Schulz-Trieglaff, M. Sturm: TOPP – The OpenMS Proteomics Pipeline “Proceedings of the 5th European Conference on Computational Biology (ECCB 2006)”, Bioinformatics 2007 23, e191-e197.