The motto of the University´s excellence strategy “Research – Relevance - Responsibility” can be understood as modern interpretation of “Attempto“ in a wider sense. Taking responsibility in biomedical sciences means translating research results from basic science into the treatment of patients. The University of Tübingen has a strong history and successful track record in such translational research. Academic drug discovery is one part of the thriving biotech spin-off scene. Currently the unique positions of TüCAD2 are RNAi-based target identification and validation strategies, fully integrated value chain from target identification up to “First into Man” strategies, access to GMP-facilities, unique and proprietary compound collections and a network of experienced staff with a strong track record. Another focus will be coaching scientists as early as possible to streamline their work plans and experimental designs in terms of validity for academic drug discovery.