Pharmazeutische Chemie

Finn Mier

PhD Student
Bioinformatician, M. Sc.
Lab for Molecular Design & Pharmaceutical Biophysics
Institute of Pharmaceutical Sciences
Eberhard Karls University Tuebingen
Auf der Morgenstelle 8
72076 Tuebingen, Germany
Phone 29-74569
E-Mail finn.mierspam prevention@uni-tuebingen.de

Curriculum Vitae

Publications

  • Expanding and Enhancing Neural Network-Based QM-AI Models for the Accurate Prediction of Halogen-π Interaction Energies in Protein Contexts
    Marc U. Engelhardt, Finn Mier, Markus O. Zimmermann, Frank M. Boeckler
    J. Chem. Inf. Model., 2026, 66, 8, 4409-4426
    (doi: https://doi.org/10.1021/acs.jcim.5c03249)
  • Covalent Drug Rescue of Multiple p53 Mutants by Stabilizing Vinyl Sulfone Fragments Hints to a Specific Refolding Mechanism for R282W
    Jason Stahlecker, Theresa Klett, Robert Spiegel, Martin Schwer, Finn Mier, Sven Aldea, Benedikt Masberg, Michael Lämmerhofer, Thilo Stehle, Frank M. Böckler
    Protein Science, 2026, 35, 6, e70629
    (doi: https://doi.org/10.1002/pro.70629)
  • MCC: automated mass and charge curation at the genome scale applied to C. tuberculostearicum
    Reihaneh Mostolizadeh, Finn Mier, Andreas Dräger
    Microbiology Spectrum, 2026, 14, 2, e03200-24
    (doi: https://doi.org/10.1128/spectrum.03200-24)
  • Tamoxifen Metabolites Acting via BKCa Orchestrate the Dynamics of K+ and Ca2+ in Breast Cancer Cells
    Selina Maier, Werner Schroth, Finn Mier, Lucas Matt, Helmut Bischof, Aiden Tamaddon, Darko Stojkov, L. Birkenfeld, M. C. Santos, D. Gross, J. Dahlen
    Journal of Biological Chemistry, 2026, 302, 2
    (doi:https://doi.org/10.1016/j.jbc.2025.111015)
  • A QM-AI Approach for the Acceleration of Accurate Assessments of Halogen-π Interactions by Training Neural Networks
    Marc U. Engelhardt, Finn Mier, Markus O. Zimmermann, Frank M. Boeckler
    J. Chem. Inf. Model., 2025, 65, 24, 13132-13144
    (doi: https://doi.org/10.1021/acs.jcim.5c02136)
  • Comparison of QM Methods for the Evaluation of Halogen−π Interactions for Large-Scale Data Generation
    Marc U. Engelhardt, Markus O. Zimmermann, Finn Mier, Frank M. Boeckler
    J. Chem. Theory Comput., 2025, 21, 12, 6174-6183
    (doi: https://doi.org/10.1021/acs.jctc.5c00456)
  • Design, Synthesis, and Molecular Evaluation of SNAr‐Reactive N‐(6‐Fluoro‐3‐Nitropyridin‐2‐yl) Isoquinolin‐3‐Amines as Covalent USP7 Inhibitors Reveals an Unconventional Binding Mode
    Larissa N. Ernst, Jason Stahlecker, Finn Mier, Ricardo A. M. Serafim, Valentin R. Wydra, Benedikt Masberg, Simon J. Jaag, Cornelius Knappe, Michael Lämmerhofer, Thilo Stehle, Matthias Gehringer, Frank M. Boeckler
    Archiv der Pharmazie, 2025, 358, 8, e70053
    (doi: https://doi.org/10.1002/ardp.70053)

Teaching

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