Zellbiologie

Publications

      2026

  • L. Dengler, F. Padovani, B. Lemke, R. Brugger, A. Benedikt, B. Westermann, B. Maček, KM. Schmoller & JC Ewald. In the absence of mitochondrial fusion unequal segregation of mitochondria drives mtDNA loss (2026) EMBO Rep 27

    2025

  • Garrigos V.,  Dengler L., Henriques D., Buceta J.,  Matallana E., Picazo C., Ewald JC., Aranda A. The peroxiredoxin Tsa1 promotes stationary phase entry by suppressing PKA activity preprint on bioRxiv

  • Garrigos V, Picazo C, Dengler L., Ewald JC., Matallana E., Aranda A.  Peroxiredoxin TSA1 Influences Acetic Acid Metabolism and pH Homeostasis in Wine Yeasts (2025) J. Agric. Food Chem.

    2023

  • Muralidhara, P., Ewald, J.C..  Protein–Metabolite Interactions Shape Cellular Metabolism and Physiology. In: Skirycz, A., Luzarowski, M., Ewald, J.C. (eds) Cell-Wide Identification of Metabolite-Protein Interactions. Methods in Molecular Biology, vol 2554. 

    2022

  • Irvali D, Schlottmann F.P., Muralidara P., Nadelsson I., Wood N.E., Doncic A.T., and Ewald J.C. When yeast cells change their mind: Cell cycle Start is reversible under starvation (2022). EMBO Journal, e110321
  • D. Schlossarek, M. Luzarowski, E. M. Sokolowska, V. P. Thirumalaikumar, L. Dengler, L. Willmitzer, J. C. Ewald and A. Skirycz . Rewiring of the protein-protein-metabolite interactome during the diauxic shift in yeast. Cellular and Molecular Life Sciences 79 (11).(2022)

  • A. P. Cuny, F. P. Schlottmann, J. C. Ewald, S. Pelet, K. M. Schmoller, Live cell microscopy: From image to insight. Biophysics Reviews 3, 021302 (2022).

    2021

  • Irvali D, Schlottmann F.P., Muralidara P., Nadelsson I., Wood N.E., Doncic A.T., and Ewald J.C. When yeast cells change their mind: Cell cycle Start is reversible under Starvation, preprint on BioRxiv
  • M. Luzarowski, R. Vicente, ..., J.C. Ewald, A. Skirycz, Global mapping of protein–metabolite interactions in Saccharomyces cerevisiae reveals that Ser-Leu dipeptide regulates phosphoglycerate kinase activity. , Commun Biol 4, 181 (2021).

  • L.Dengler, M. Örd, L.M. Schwab, M.Loog, J.C. Ewald, Regulation of trehalase activity by multi-site phosphorylation and 14-3-3 interaction, Scientific Reports 

    2019

  • L. Zhang, S. Winkler, F. Schlottmann, O.C. Kohlbacher, J. E. Elias, J.M. Skotheim, J.C. Ewald, Multiple layers of phospho-regulation coordinate metabolism and the cell cycle in budding yeast, Front. Cell Dev. Biol., 2019 https://doi.org/10.3389/fcell.2019.00338

    2018

  • M. Solaki, J.C. Ewald, Fueling the Cycle: CDKs in Carbon and Energy Metabolism. Front. Cell Dev. Biol., 2018. 6, 93. doi:  10.3389/fcell.2018.00093

  • J.C. Ewald, How yeast coordinates metabolism, growth and division. Current Opinion in Microbiology, 2018. 45: p. 1-7. https://doi.org/10.1016/j.mib.2017.12.012

    2008-2016

  • J.C. Ewald, A.Kuehne, N. Zamboni and J. M. Skotheim (2016) "The yeast cyclin dependent kinase routes carbon fluxes to fuel cell cycle progression“. Mol. Cell, 62 (4):532-45 (highlighted in Faculty1000)
  • E.Peroza, J.C. Ewald, G. Parakkal, J.M. Skotheim and Nicola Zamboni (2015). "A genetically encoded FRET sensor reveals in vivo trehalose-6-phosphate dynamics.“ Anal Biochem,474, 1-7
  • J.C. Ewald, T. Matt and N. Zamboni (2013). "The integrated response of primary metabolites to gene deletions and the environment." Mol Biosyst 9(3): 440-446.
  • G.G. Zampar, A. Kummel, J. Ewald, S. Jol, B. Niebel, P. Picotti, R. Aebersold, U. Sauer, N. Zamboni and M. Heinemann (2013). "Temporal system-level organization of the switch from glycolytic to gluconeogenic operation in yeast." Mol Syst Biol 9: 651.
  • (Review) J.J. Turner, J.C. Ewald and J.M. Skotheim (2012). "Cell size control in yeast." Curr Biol 22(9): R350-359. (cited in Bruce Alberts „Molecular Biology of the Cell“ text book)
  • J.C. Ewald, S. Reich, S. Baumann, W.B. Frommer and N. Zamboni (2011). "Engineering genetically encoded nanosensors for real-time in vivo measurements of citrate concentrations." PLoS One 6(12):
  • C. Bermejo*, J.C. Ewald*, V. Lanquar*, A. Jones and W.B. Frommer (2011). "In vivo biochemistry – quantifying fluxes in individual cells or cultures of yeast." Biochem. Journ. 438(1): 1-10.
  • A. Kummel, J.C. Ewald, S.M. Fendt, S.J. Jol, P. Picotti, R. Aebersold, U. Sauer, N. Zamboni and M. Heinemann (2010). "Differential glucose repression in common yeast strains in response to HXK2 deletion." FEMS Yeast Res 10(3): 322-332.
  • A.B. Canelas, N. Harrison, A. Fazio, J. Zhang, J.P. Pitkanen, J. van den Brink, B.M. Bakker, L. Bogner, J. Bouwman, J.I. Castrillo, A. Cankorur, P. Chumnanpuen, P. Daran-Lapujade, D. Dikicioglu, K. van Eunen, J.C. Ewald, et al (2010). "Integrated multilaboratory systems biology reveals differences in protein metabolism between two reference yeast strains." Nat Commun 1: 145.
  • T. Hardiman, H. Meinhold, J. Hofmann, J.C. Ewald, M. Siemann-Herzberg and M. Reuss (2010). "Prediction of kinetic parameters from DNA-binding site sequences for modeling global transcription dynamics in Escherichia coli." Metab Eng 12(3): 196-211.
  • J.C. Ewald, S. Heux and N. Zamboni (2009). "High-throughput quantitative metabolomics: workflow for cultivation, quenching, and analysis of yeast in a multiwell format." Anal Chem 81(9): 3623-3629.
  • J.M. Buscher, D. Czernik, J.C. Ewald, U. Sauer and N. Zamboni (2009). "Cross-platform comparison of methods for quantitative metabolomics of primary metabolism." Anal Chem 81(6): 2135-2143.
  • T. Hardiman, J.C. Ewald, K. Lemuth, M. Reuss and M. Siemann-Herzberg (2008). "Quantification of rRNA in Escherichia coli using capillary gel electrophoresis with laser-induced fluorescence detection." Anal Biochem 374(1): 79-86.

  • T. Hardiman, V. Windeisen, J.C. Ewald, S. Zibek, P. Schlack, J. Rebell, M. Reuss and M. Siemann-Herzberg (2008). "In vitro synthesis and characterization of guanosine 3',5'-bis(diphosphate)." Anal Biochem 383(2): 337-339.