Interfakultäres Institut für Mikrobiologie und Infektionsmedizin

Short CV - Dr. Sofía Doello Román

2008 – 2013: Diploma in Biotechnology at Universidad Pablo de Olavide (Spain)

2013 – 2014: Visiting scholar at University of Tübingen

2014 – 2016: Master of Science in Molecular Biosciences and Bioengineering at University of Hawai’i Manoa (USA) funded by Fulbright Scholarship

“Quantitative proteomics to elucidate the molecular mechanism of γ-oryzanol against non-small cell lung cancer”. Supervised by Prof. Dr. Qing Xiao Li

2017 – 2021: Ph.D. in Biology at University of Tübingen

“Energy and carbon metabolism during the awakening from metabolic dormancy in cyanobacteria”. Supervised by Prof. Dr. Karl Forchhammer.

Research interests: Regulation of cyanobacterial metabolism in response to nitrogen starvation

Publications

Selim K, Zimmer E, Yehia H, and Doello S. 2021. Molecular and Cellular Mechanisms Underlying the Microbial Survival Strategies: Insights into Temperature and Nitrogen Adaptations. In: Climate Change and the Microbiome. Soil Biology, vol 63. Springer, Cham. doi: 10.1007/978-3-030-76863-8_36

Neumann N, Doello S, and Forchhammer K. 2021. “Recovery of Unicellular Cyanobacteria from Nitrogen Chlorosis: A Model for Resuscitation of Dormant Bacteria.” Microb. Physiol. doi: 10.1159/000515742.

Doello S, Burkhardt M, and Forchhammer K. 2021. “The Essential Role of Sodium Bioenergetics and ATP Homeostasis in the Developmental Transitions of a Cyanobacterium.” Curr. Biol. 31: 1–10.

Moritz K, Doello S, Gutekunst K, and Forchhammer K. 2019. “PHB Is Produced from Glycogen Turn-over during Nitrogen Starvation in Synechocystis Sp. PCC 6803.” Int. J. Mol. Sci. 20 (1942): 1–14.

Doello S, Klotz A, Makowka A, Gutekunst K, and Forchhammer K. 2018. “A Specific Glycogen Mobilization Strategy Enables Rapid Awakening of Dormant Cyanobacteria from Chlorosis.” Plant Physiol. 177: 594–603.

Doello S, Liang Z, Cho IK, Kim JB, and Li QX. 2018. “Cytotoxic Effects of 24-Methylenecyloartanyl Ferulate on A549 Nonsmall Cell Lung Cancer Cells through MYBBP1A Up-Regulation and AKT and Aurora B Kinase Inhibition.” J. Agric. Food Chem. 66 (14): 3726–33.

Klotz A, Reinhold E, Doello S, and Forchhammer K. 2015. “Nitrogen Starvation Acclimation in Synechococcus elongatus: Redox-Control and the Role of Nitrate Reduction as an Electron Sink.” Life 5 (1): 888–904.