IFIB – Interfakultäres Institut für Biochemie

Selected publications Jansen lab


  Singer-Krüger B and Jansen RP, 2022. Proteomic mapping by APEX2-catalyzed proximity labeling in Saccharomyces cerevisiae semipermeabilized cells. Methods Mol. Biol. 2477, 261-274. doi: 10.1007/978-1-0716-2257-5_15.


  Pfeiffer-Guglielmi B and Jansen RP, 2021. The Motor Neuron-Like Cell Line NSC-34 and Its Parent Cell Line N18TG2 Have Glycogen that is Degraded Under Cellular Stress. Neurochem Res. 46, 1567-1576. doi: 10.1007/s11064-021-03297-y

  Weissinger R, Heinold L, Akram S, Jansen RP, Hermesh O, 2021. RNA Proximity Labeling: A New Detection Tool for RNA-Protein Interactions. Molecules 26, 2270. doi: 10.3390/molecules26082270.


  Singer-Krüger B, Fröhlich T, Franz-Wachtel M, Nalpas N, Macek, B and Jansen RP, 2020. APEX2-mediated proximity labeling resolves protein networks in Saccharomyces cerevisiae cells. FEBS J 287, 325-344. doi: 10.1111/febs.15007

  Mukherjee J, Franz-Wachtel M, Macek B and Jansen RP, 2020. Interactome Identification via RNA-BioID in Mouse Embryonic Fibroblasts. Bio Protoc. 5, e3476. doi: 10.21769/BioProtoc.3476.


  Bethune J, Jansen RP, Feldbrügge M and Zarnack K, 2019. Membrane-associated RNA-binding proteins orchestrate organelle-coupled translation. Trends Cell Biol 29, 178-188.

  Manchalu S, Mittal N, Spang A, Jansen RP, 2019. Local translation of yeast ERG4 mRNA at the endoplasmic reticulum requires the brefeldin A resistance protein Bfr1. RNA 25, 1661-1672. doi: 10.1261/rna.072017.119.

  Mukherjee J, Hermesh O, Eliskovich C, Nalpas N, Franz-Wachtel M, Macek B and Jansen RP, 2019. ß-actin mRNA interactome mapping by proximity biotinylation. Proceedings Natl. Acad. Sci. USA 116 12863-12872. doi: 10.1073/pnas.1820737116.


  Niessing D, Jansen RP, Pohlmann T and Feldbrügge M2018. mRNA transport in fungal top models. WILEY Interdiscip Rev RNA. doi: 10.1002/wrna.1453.

  Syed MI, Moorthy BT, Jenner A, Fetka I and Jansen RP, 2018. Signal sequence-independent targeting of MID2 mRNA to the endoplasmic reticulum by the yeast RNA-binding protein Khd1p. FEBS Lett. 592, 1870-1881.

  Cheng MHK, Hoffmann PC, Franz-Wachtel M, Sparn C, Seng C, Macek B and Jansen RP, 2018. The RNA-binding protein Scp160p facilitates aggregation of many endogenous Q/N-rich proteins. Cell Rep. 24, 20-26.


  Cheng MHK and Jansen RP2017. A jack of all trades: The RNA-binding protein vigilin. WILEY Interdiscip Rev RNA. doi: 10.1002/wrna.1448.

  Edelmann FT, Schlund A, Heym RG, Jenner A, Niedner-Boblenz A, Syed MI, Paillart JC, Stehle R, Janowski R, Sattler M, Jansen RP, and Niessing D2017. Molecular Architecture and dynamics of ASH1 mRNA recognition by its mRNA transport complex. Nat.Struct.Mol.Biol. 24, 152-161.


  Jansen RP, Niessing D, Baumann S, and Feldbrügge M2014. mRNA transport meets membrane traffic. Trends Genet.30, 408-417.

  Singer-Krüger B and Jansen RP2014. Here, there, everywhere. mRNA localisation in budding yeast. RNA Biol. 11, 1031-1039.

  Hermesh O, Genz C, Yofe I, Sinzel M, Rapaport D, Schuldiner M and Jansen RP2014. Yeast phospholipid biosynthesis is linked to mRNA localization. J Cell Sci. 127, 3373-3381.

  Pfeiffer-Guglielmi B, Dombert B, Jablonka S,Hausherr V, van Thriel C, Schöbel N and Jansen RP, 2014. Axonal and dendritic localization of mRNAs for glycogen-metabolizing enzymes in cultured rodent neurons. BMC Neurosci 15, 70.

  Hirschmann WD, Westendorf H, Mayer A, Cannarozzi G, Cramer P and Jansen RP, 2014. Scp160p is required for translational efficiency of codon-optimized mRNAs in yeast. Nuc Acids Res. 42, 4043-4055.

  Moorthy BT and Jansen RP2014. mRNA localization. in Fungal RNA Biology (eds. Sesma A and von der Haar T) . Springer Publishing.


  Niedner A, Müller M, Moorthy, BT, Jansen RP, Niessing D, 2013. Role of Loc1p in assembly and reorganization of nuclear ASH1 ribonucleoprotein particles in yeast. Proc.Natl.Acad.Sci. USA 110,E5049-5058.

  Genz C, Fundakowski J, Hermesh O, Schmid, M, and Jansen RP, 2013. Association of the yeast RNA-binding protein She2p with the tubular endoplasmic reticulum depends on membrane curvature. J Biol Chem 288, 32384-32393.

  Hermesh O, and Jansen RP, 2013. Take the (RN)A-train: localization of mRNA to the endoplasmic reticulum. Biochim Biophys Acta 1833, 2519-2525.


  Fundakowski J, Hermesh O, and Jansen RP, 2012. Localization of a subset of yeast mRNAs depends on inheritance of endoplasmic reticulum. Traffic 13, 1642-1652.

  Jansen RP, Niessing D, 2012. Assembly of mRNA-protein complexes for directional mRNA transport in eukaryotes -- an overview . Curr Protein Pept Sci 13, 284-293.


Müller M, Heym RG, Mayer A, Kramer K, Schmid M, Cramer P, Urlaub H, Jansen RP, Niessing D., 2011. A cytoplasmic complex mediates specific mRNA recognition and localization in yeast . PLoS Biol 9, e1000611.


Heuck A, Fetka I, Brewer DN, Hüls D, Munson M, Jansen RP, Niessing D., 2010. The structure of the Myo4p globular tail and its function in ASH1 mRNA localization. J Cell Biol 189, 497-510.


Müller M, Richter K, Heuck A, Kremmer E, Buchner J, Jansen RP, Niessing D., 2009. Formation of She2p tetramers is required for mRNA binding, mRNP assembly, and localization. RNA 15, 2002-2012.


Jellbauer, S. and R.-P. Jansen, 2008. A putative function of the nucleolus in the assembly or maturation of specialized messenger ribonucleoprotein complexes. RNA Biology 5, 9-13.

Du, T.-G., Jellbauer, S., Müller, M., Schmid, M., Niessing, D., and R.-P. Jansen, 2008. Nuclear transit of the RNA-binding protein She2p is required for translational control of localized ASH1 mRNA. EMBO Rep. 9, 781-787.

Lange, S., Katayama, Y., Schmid, M., Burkacky, O., Bräuchle, C., Lamb, D.C., and R.-P. Jansen, 2008. Simultaneous transport of different localized mRNA species revealed by live-cell imaging. Traffic 9, 1256-1267.


Heuck, A., Du, T.-G., Jellbauer, S., Richter, K., Kruse, C., Jaklin, S., Müller, M., Buchner, J., Jansen, R.-P. and D. Niessing, 2007. Monomeric myosin V uses two binding regions for the assembly of stable translocation complexes. Proc.Natl.Acad.Sci. USA 104,19778-19783.

T.-G. Du, M. Schmid, and R.-P. Jansen, 2007. Why cells move messages: the biological functions of mRNA localization. Semin Cell Dev Biol.18, 171-7.

M. Schmid, A. Jaedicke, T.-G. Du, and R.-P. Jansen, 2006. Coordination of endoplasmic reticulum and mRNA localization to the yeast bud. Curr. Biol. 16, 1538-1543.

Jansen, R.-P., and M. Kiebler, 2005. Intracellular RNA sorting, transport and localization. Nat. Struct. Mol. Biol. 12, 826-829.

S. Wesche, M. Arnold, and R.-P. Jansen, 2003. The UCS-domain protein She4p binds to myosin motor domains and is essential for class I and class V myosin function. Curr. Biol. 13, 715-724.

C. Kruse, A. Jaedicke, J. Beaudouin, F. Böhl, D. Fering, T. Güttler, J. Ellenberg, and R.-P. Jansen, 2002. Ribonucleoprotein-dependent localization of the yeast class V myosin Myo4p. J. Cell Biol. 159, 971-982.

R.-P. Jansen, 2001. RNA localization: Message on the move. Nature Reviews Mol. Cell. Biol. 2, 247-256.

F. Böhl, C. Kruse, A. Frank, D. Ferring, and R.-P. Jansen, 2000. She2p, a novel RNA-binding protein tethers ASH1 mRNA to the Myo4p myosin motor via She3p. EMBO J. 19, 5514-5524.

R. Long, I. Gonzales, R. Singer, K. Nasmyth, and R.-P. Jansen. 1997. Mating type switching in yeast controlled by asymmetric localization of ASH1 mRNA. Science 277: 383-387.

N. Bobola, R.-P. Jansen, T. H. Shin, and K. Nasmyth. 1996. Asymmetric Accumulation of Ash1p in postanaphase nuclei depends on a myosin and restricts yeast mating-type switching to mother cells. Cell 84: 699-709.

R.-P. Jansen, C. Dowzer, C. Michaelis, M. Galova, and K. Nasmyth. 1996. Mother cell-specific HO expression in budding yeast depends on the unconventional myosin Myo4p and other cytoplasmic proteins. Cell 84: 687-698.