Publications
2024
Comprehensive coverage of glycolysis and pentose phosphate metabolic pathways by isomer-selective accurate targeted hydrophilic interaction liquid chromatography-tandem mass spectrometry assay
Kristian Serafimov, Michael Lämmerhofer, Anal. Chem., (2024);
https://doi.org/10.1021/acs.analchem.4c03490.
#Wide-pore fully porous mixed-mode octyl/pyridyl-bonded silica material with pH-dependent surface charge reversal for high-performance hydrophobic charge-induction chromatography of proteins
Marc Wolter, Christoph Barth, Mirna Maalouf, Markus Kramer, Adrian Sievers-Engler, Michael Lämmerhofer, J. Chromatogr. A, (2024) 465429;
doi:10.1016/j.chroma.2024.465429.
Determination of double bond positions in unsaturated fatty acids by pre-column derivatization with dimethyl and dipyridyl disulfide followed by LC-SWATH-MS analysis
Matthias Olfert, Cornelius Knappe, Adrian Sievers-Engler, Benedikt Masberg, Michael Lämmerhofer, Anal. Bioanal. Chem., (2024);
https://doi.org/10.1007/s00216-024-05542-z.
Targeted UHPLC-MS/MS assay for the quantification of medium-chain phosphatidylcholines in platelets of coronary artery disease patients
Tamara Janker, Adrian Brun, Adrian Sievers-Engler, Kristina Dittrich, Meinrad Gawaz, Michael Lämmerhofer, J. Chromatogr. Open, 6 (2024) 100160,
https://doi.org/10.1016/j.jcoa.2024.100160
Evaluation of a covalent library of diverse warheads (CovLib) binding to JNK3, USP7 or p53
Theresa Klett, Martin Schwer, Larissa N Ernst, Marc U Engelhardt, Simon J Jaag, Benedikt Masberg, Cornelius Knappe, Michael Lämmerhofer, Matthias Gehringer, Frank M. Boeckler, Drug Design, Development and Therapy, 18, 2024, 1–27.
https://doi.org/10.2147/DDDT.S466829
Non-enantioselective, enantioselective, and two-dimensional liquid chromatography coupled with tandem mass spectrometry for the study of stereochemical disposition of oxylipins in cGMP-regulated hemin-treated platelets
Xiaoqing Fu, Cornelius Knappe, Anne-Katrin Rohlfing, Meinrad P. Gawaz and Michael Lämmerhofer, J. Phar, Biomed. Anal., 248 (2024) 116328,
https://doi.org/10.1016/j.jpba.2024.116328
Two-dimensional sequential selective comprehensive chiral×reversed phase liquid chromatography of synthetic phosphorothioate oligonucleotide diastereomers
Feiyang Li, Cornelius Knappe, Niklas Carstensen, Enrico Favorat, Mimi Gao, Wiebke Holkenjans, Terence Hetzel, Reinhard Pell, Michael Lammerhofer, J. Chromatogr. A, 1730 (2024) 465076,
https://doi.org/10.1016/j.chroma.2024.465076
Solving the retention time repeatability problem of hydrophilic interaction liquid chromatography
Kristian Serafimov, Cornelius Knappe, Feiyang Li, Adrian Sievers-Engler, Michael Lämmerhofer, J. Chromatogr. A, 1730 (2024) 465060;
https://doi.org/10.1016/j.chroma.2024.465060
Lipase-mediated detoxification of host-derived antimicrobial fatty acids by Staphylococcus aureus
Arnaud Kengmo Tchoupa, Ahmed M. A. Elsherbini, Xiaoqing Fu, Oumayma Ghaneme, Lea Seibert, Marieke A. Böcker, Marco Lebtig, Justine Camus, Stilianos Papadopoulos Lambidis, Birgit Schittek, Dorothee Kretschmer, Michael Lämmerhofer, Andreas Peschel Commun. Biol., 7 (2024) 572.
https://doi.org/10.1038/s42003-024-06278-3
Machine learning insights into thrombo-ischemic risks and bleeding events through platelet lysophospholipids and acylcarnitine species.
Tobias Harm, Xiaoqing Fu, Moritz Frey, Kristina Dittrich, Adrian Brun, Tatsiana Castor, Oliver Borst, Karin Anne Lydia Müller, Tobias Geisler, Dominik Rath, Michael Lämmerhofer, Meinrad Paul Gawaz, Sci Rep 14, 6089 (2024).
https://doi.org/10.1038/s41598-024-56304-x
Three-Minute Enantioselective Amino Acid Analysis by Ultra-High Performance Liquid Chromatography Drift Tube Ion Mobility-Mass Spectrometry Using a Chiral Core-Shell Tandem Column Approach
Simon Jonas Jaag, Younes Valadbeigi, Tim Causon, Harald Gross, Michael Lämmerhofer. Anal. Chem., (2024);
https://doi.org/10.1021/acs.analchem.3c05426
The ubiquitin-proteasome pathway inhibitor TAK-243 has major effects on calcium handling in mammalian cells
Xiaokong Gao, Katherine R Keller, Caden G Bonzerato, Peng Li, Michael Laemmerhofer, Richard J H Wojcikiewicz, Biochim. Biophys. Acta. Mol. Cel.l Res., 1871 (2024) 119618
https://doi.org/10.1016/j.bbamcr.2023.119618
Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity
Philipp Flury, Julian Breidenbach, Nadine Krüger, Rabea Voget, Laura Schäkel, Yaoyao Si, Vesa Krasniqi, Sara Calistri, Matthias Olfert, Katharina Sylvester, Cheila Rocha, Raphael Ditzinger, Alexander Rasch, Stefan Pöhlmann, Thales Kronenberger, Antti Poso, Katharina Rox, Stefan A. Laufer, Christa E. Müller, Michael Gütschow, Thanigaimalai Pillaiyar, ACS Pharmacol. Transl. Sci., (2024)
2023
cGMP modulates hemin-mediated platelet death
Anne-Katrin Rohlfing, Marcel Kremser, David Schaale, Valerie Dicenta-Baunach, Zoi Laspa, Xiaoqing Fu, Laimdota Zizmare, Manuel Sigle, Tobias Harm, Patrick Münzer, Andreas Pelzer, Oliver Borst, Christoph Trautwein, Robert Feil, Karin Müller, Tatsiana Castor, Michael Lämmerhofer, Meinrad P. Gawaz, Thrombosis Research, (2023);
https://doi.org/10.1016/j.thromres.2023.12.008
Commensal production of a broad spectrum and short-lived antimicrobial peptide polyene eliminates nasal Staphylococcus aureus
Benjamin O. Torres Salazar, Taulant Dema, Nadine A. Schilling, Daniela Janek, Jan Bornikoel, Anne Berscheid, Ahmed M. A. Elsherbini, Sophia Krauss, Simon J. Jaag, Michael Lämmerhofer, Min Li, Norah Alqahtani, Malcolm J. Horsburgh, Tilmann Weber, José Manuel Beltrán-Beleña, Heike Brötz-Oesterhelt, Stephanie Grond, Bernhard Krismer, Andreas Peschel, Nature Microbiology, (2023)
https://doi.org/10.1038/s41564-023-01544-2
mitoBKCa is functionally expressed in murine and human breast cancer cells and promotes metabolic reprogramming
Helmut Bischof, Selina Maier, Piotr Koprowski, Bogusz Kulawiak, Sandra Burgstaller, Joanna Jasińska, Kristian Serafimov, Dominic Gross, Werner Schroth, Lucas Matt, David Arturo Juarez Lopez, Irina Bonzheim, Florian A. Büttner, Falko Fend, Matthias Schwab, Andreas L. Birkenfeld, Roland Malli, Michael Lämmerhofer, Piotr Bednarczyk, Adam Szewczyk, Robert Lukowski, eLife 12 (2023) RP92511
https://doi.org/10.7554/eLife.92511.1
Quantitative analysis of the glutathione pathway cellular metabolites by targeted liquid chromatography-tandem mass spectrometry
Kristian Serafimov, Yüsra Aydin, Michael Lämmerhofer, J. Sep. Sci., (2023)
https://doi.org/10.1002/jssc.202300780
Crosslinked polysiloxane-coated stable bond O-9-(2,6-diisopropylphenylcarbamoyl)quinine and quinidine chiral stationary phases as well as application in enantioselective cryo-HPLC
Ulrich Woiwode, Adrian Sievers-Engler, Michael Lämmerhofer, Electrophoresis, (2023)
https:///doi.org/10.1002/elps.202300182
Large‑scale lipidomics profiling reveals characteristic lipid signatures associated with an increased cardiovascular risk
Tobias Harm, Kristina Dittrich, Adrian Brun, Xiaoqing Fu, Moritz Frey, Alvaro Petersen Uribe, Frederic‑ Joaquim Schwarz, Anne‑ Katrin Rohlfing, Tatsiana Castor, Tobias Geisler, Dominik Rath, Michael Lämmerhofer, Meinrad P. Gawaz, Clin. Res. Cardiol., (2023)
https://doi.org/10.1007/s00392-023-02260-x
Automated Sample Preparation with 6-Aminoquinolyl-N -hydroxysccinimidyl Carbamate and Iodoacetamide Derivatization Reagents for Enantioselective Liquid Chromatography Tandem Mass Spectrometry Amino Acid Analysis
Feiyang Li, Ryan Karongo, Despoina Mavridou, Jeannie Horak, Adrian Sievers-Engler, Michael Lämmerhofer, J. Chromatogr. A, 1708 (2023) 464349
https://doi.org/10.1016/j.chroma.2023.464349
Principles and Applications of CF2X Moieties as Unconventional Halogen Bond Donors in Medicinal Chemistry, Chemical Biology, and Drug Discovery
Sebastian Vaas, Markus O. Zimmermann, Dieter Schollmeyer, Jason Stahlecker, Marc U. Engelhardt, Janosch Rheinganz, Bernhard Drotleff, Matthias Olfert, Michael Lämmerhofer, Markus Kramer, Thilo Stehle, and Frank M. Boeckler
https://doi.org/10.1021/acs.jmedchem.3c00634
Ion-pair-free RPLC-MS of synthetic oligonucleotides Impurity analysis of siRNA with a polybutylene terephthalate-based column
Feiyang Li, Shenkai Chen, Sylwia Studzińska, Michael Lämmerhofer, chrom+food forum 06 (2023) 4-6.
Evaluation of Kinetic Performance of Reversed-Phase Columns for Protein Separations by Gradient Kinetic Plots
Simon Jaag, Michael Lämmerhofer, LCGC Supplement, May 2 (2023)
https://doi.org/10.56530/lcgc.eu.bm1469g6
Comprehensive reversed-phase×chiral two-dimensional liquid chromatography coupled to quadrupole-time-of-flight tandem mass spectrometry with post-first dimension flow splitting for untargeted enantioselective amino acid analysis
Ryan Karongo, Jeannie Horak, Michael Lämmerhofer, J. Sep.Sci., (2023)
http://doi.wiley.com/10.1002/jssc.202300351
Profiling of branched chain and straight chain saturated fatty acids by ultra-high performance liquid chromatography-mass spectrometry
Xiaoqing Fu, Nourhane Hafza, Friedrich Götz, Michael Lämmerhofer, J. Chromatogr. A, (2023) 464111
https://doi.org/10.1016/j.chroma.2023.464111
Chiral stationary phases derived from cinchona alkaloids
Michael Lämmerhofer, Wolfgang Lindner, in: Quezia B Cass, Maria Elizabeth Tiritan, Juliana Cristina Barreiro and João Marco Batista Junior (eds.), Chiral Separations and Stereochemical Elucidation: Fundamentals, Methods, and Applications, Chapter 11, Wiley, 2023, p. 415-472, ISBN: 978-1-119-80225-9.
The Subtilisin-Like Protease Furin Regulates Hemin-Dependent Ectodomain Shedding of Glycoprotein VI.
Fink A, Rohlfing AK, Dicenta V, Schaale D, Kremser M, Laspa Z, Sigle M, Fu X, Pelzer A, Fischer M, Münzer P, Castor T, Müller KAL, Borst O, Lämmerhofer M, Gawaz MP. Thromb. Haemost., (2023)
https://doi.org/10.1055/s-0043-1768057
Polybutylene terephthalate-based stationary phase for for ion-pair-free reversed-phase liquid chromatography of small interfering RNA. Part 2: Use for selective comprehensive two-dimensional liquid chromatography
Feiyang Li, Shenkai Chen, Sylwia Studzińska, Michael Lämmerhofer, J. Chromatogr. A, (2023) 464069,
https://doi.org/10.1016/j.chroma.2023.464069
Ionenpaar-freie RPLC-MS von Oligonukleotiden: Anwendung für die Verunreinigungsanalytik von siRNA mithilfe einer Polybutylenterephthalat-basierten Säule
Feiyang Li, Shenkai Chen, Sylwia Studzińska, Michael Lämmerhofer, chrom+food forum 04 (2023) 44-46.
Basic principles for the selection of liquid chromatographic modes for specific applications.
Carlos Calderón, Michael Lämmerhofer, in: Salvatore Fanali, Bezhan Chankvetadze, Paul R. Haddad, Colin F. Poole and Marja-Liisa Riekkola (Eds.) Handbooks in Separation Science. Liquid Chromatography Volume 2 Applications, 3rd edition, Elsevier, Amsterdam, Netherlands, ISBN: 978-0-323-99969-4
https://doi.org/10.1016/B978-0-323-99969-4.00101-7
Nutritional lipidomics for the characterization of lipids in food
Carlos Calderón, Michael Lämmerhofer, Advances in Food and Nutrition Research (Book series), 2023, Elsevier, Amsterdam.
https://doi.org/10.1016/bs.afnr.2022.12.002
Statin Treatment Is Associated with Alterations in the Platelet Lipidome
Tobias Harm, Moritz Frey, Kristina Dittrich, Andreas Goldschmied, Anne-Katrin Rohlfing,
Xiaoqing Fu, Adrian Brun, Tatsiana Castor, Dominik Rath, Karin Müller, Michael Lämmerhofer, Meinrad Gawaz, Thrombosis und Haemostasis, (2023),
https://doi.org/10.1055/s-0043-1764353
Polybutylene terephthalate-based stationary phase for for ion-pair-free reversed-phase liquid chromatography of small interfering RNA. Part 1: Direct coupling with mass spectrometry
Feiyang Li, Shenkai Chen, Sylwia Studzińska, Michael Laemmerhofer, J. Chromatogr. A, (2023) 463898,
https://doi.org/10.1016/j.chroma.2023.463898
Application of Two-Dimensional Liquid Chromatography to the Analysis of Chiral and Structurally Similar Molecules
Michael Lämmerhofer, Carlos Calderón, in: Dwight R. Stoll and Peter W. Carr (Eds.), Multi-Dimensional Liquid Chromatography: Principles, Practice, and Applications, CRC Press, Boca Raton, FL, USA (Taylor and Francis Group, London), 2023. ISBN 9780367547660, 1st Edition,
https://doi.org/10.1201/9781003090557
2022
Isomer selectivity of mixed-mode and hydrophilic interaction liquid chromatography coupled to tandem mass spectrometry for sugar phosphates of glycolysis and pentose phosphate pathways
Min Su, Kristian Serafimov, Peng Li, Cornelius Knappe, Michael Lämmerhofer, J. Chromatogr. A, (2022) 463727;
https://doi.org/10.1016/j.chroma.2022.463727
Application of cholesterol stationary phase for the separation and identification of siRNA impurities by two-dimensional liquid chromatography-mass spectrometry
Sylwia Studzińska, Feiyang Li, Michał Szumski, Bogusław Buszewski, Michael Lämmerhofer, Int. J. Mol. Sci., 23 (2022), 14960;
https://doi.org/10.3390/ijms232314960
UHPLC-MS/MS method for chiral separation of 3-hydroxy fatty acids on amylose-based chiral stationary phase and its application for the enantioselective analysis in plasma and platelets
Xiaoqing Fu, Zhanjian Xu, Meinrad Gawaz, Michael Lämmerhofer, J. Pharm. Biomed. Anal., (2022) 115151
https://doi.org/10.1016/j.jpba.2022.115151
Branched medium-chain fatty acid profiling and enantiomer separation of anteiso-forms of teicoplanin fatty acyl side chain RS3 using UHPLC-MS/MS with polysaccharide columns
Christian Geibel, Matthias Olfert, Cornelius Knappe, Kristian Serafimov, Michael Lämmerhofer, J. Pharm. Biomed. Anal., (2022)
https://doi.org/10.1016/j.jpba.2022.115162
Comprehensive Online Reversed-phase×Chiral Two-dimensional Liquid Chromatography-Mass Spectrometry with Data-independent SWATH-Acquisition for Untargeted Enantioselective Amino Acid Analysis
Ryan Karongo, Jeannie Horak, Michael Lämmerhofer, Anal. Chem., (2022)
https://doi.org/10.1021/acs.analchem.2c03042.
Revisiting a challenging p53 binding site: a diversity-optimized HEFLib reveals diverse binding modes in T-p53C-Y220C
Jason Stahlecker, Theresa Klett, Martin Schwer, Simon Jaag, Marcel Dammann, Larissa N. Ernst, Michael Braun, Markus O. Zimmermann, Markus Kramer, Michael Lämmerhofer, Thilo Stehle, Murray Colese, Frank M. Boeckler, RSC Med. Chem., (2022)
https://doi.org/10.1039/D2MD00246A.
Generation of 13C-labeled inositol and inositol phosphates by stable isotope labeling cell culture for quantitative metabolomics
Peng Li, Michael Lämmerhofer, Anal. Chem., (2022)
https://doi.org/10.1021/acs.analchem.2c02819
Retentionskinetiken unter der Lupe: Ein genauer Blick auf die Kinetiken in vollporösen (FPP) und oberflächenporösen Partikeln (SPP) mit chiralen ZWIX-Selektoren
Christian Geibel, Kristina Dittrich, Ulrich Woiwode, Michal Kohout, Tong Zhang, Wolfgang Lindner, Michael Lämmerhofer, chrom+food forum, 06 (2022) 6-8
UHPLC-ESI-MS/MS assay for quantification of endocannabinoids in cerebrospinal fluid using surrogate calibrant and surrogate matrix approaches
Ece Aydin, Malgorzata Cebo, Justyna Mielnik, Hardy Richter, Rebecca Schüle, Adrian Sievers-Engler, Piotr Młynarz, Michael Lämmerhofer, J. Pharm. Biomed. Anal., 222 (2023) 115090
https://doi.org/10.1016/j.jpba.2022.115090
Lower affective empathy in oral contraceptive users: a cross-sectional fMRI study
Kimmig A-C.S., Wildgruber D., Gärtner A., Drotleff B., Krylova M., Lämmerhofer M., Sundström-Poromaa I., Derntl B., Cerebral Cortex, bhac345,
https://doi.org/10.1093/cercor/bhac345
Metabolic profiling workflow for urine, plasma and cell extracts by targeted hydrophilic interaction liquid chromatography-tandem mass spectrometry
Kristian Serafimov, Michael Lämmerhofer, J. Chromatogr. A, 1684 (2022) 463556
https://doi.org/10.1016/j.chroma.2022.463556
Starting or Discontinuing the Pill – changes in progestogens reflected by resting-state connectivity and positive mood
Kimmig A-C.S, Friedrich P. Drotleff B. Lämmerhofer M. Sundström-Poromaa I., Weis S., Derntl B., BioRxiv, 2022
https://doi.org/10.1101/2022.09.21.508780
Quality-by-Design Approach for Development of Aqueous Headspace Microextraction GC-MS Method for Targeted Metabolomics of Small Aldehydes in Plasma of Cardiovascular Patients
Rasha S. Hanafi, Michael Lämmerhofer, Anal. Chim. Acta, (2022) 340176
https://doi.org/10.1016/j.aca.2022.340176
Targeted analysis of sugar phosphates from glycolysis pathway by phosphate methylation with liquid chromatography coupled to tandem mass spectrometry
Peng Li, Min Su, Madhumita Chatterjee, Michael Lämmerhofer, Anal. Chim. Acta, 1221 (2022) 340099
https://doi.org/10.1016/j.aca.2022.340099
Advanced unified monophasic lipid extraction protocol with wide coverage on the polarity scale optimized for large-scale untargeted clinical lipidomics analysis of platelets
Xiaoqing Fu, Carlos Calderón, Tobias Harm, Meinrad Gawaz, Michael Lämmerhofer, Anal. Chim. Acta, (2022), 340155
https://doi.org/10.1016/j.aca.2022.340155
Kinetic performance comparison of superficially porous, fully porous and monolithic reversed-phase columns by gradient kinetic plots for the separation of protein biopharmaceuticals
Simon Jaag, Chunmei Wen, Benjamin Peters, Michael Lämmerhofer, J. Chromatogr. A, 1676 (2022), 463251
https://doi.org/10.1016/j.chroma.2022.463251
Aß1-42 peptide toxicity on neuronal cells: a lipidomic study
Lara Davani, Xiaoqing Fu, Angela De Simone, Peng Li, Serena Montanari, Michael Lämmerhofer, and Vincenza Andrisano, J. Pharm. Biomed. Anal., (2022) 114876
https://doi.org/10.1016/j.jpba.2022.114876
Study of microheterogeneity of silatrane-based silica surface bonding chemistry and its optimization for the synthesis of chiral stationary phases for enantioselective liquid chromatography
Christian Geibel, Markus Kramer, Michael Lämmerhofer, J. Chromatogr. A, (2022) 463138
https://doi.org/10.1016/j.chroma.2022.463138
Development and chromatographic exploration of stable-bonded crosslinked amino silica against classical amino phases
Marc Wolter, Christian Geibel, Matthias Olfert, Min Su, Wolfgang Bicker, Wolfgang Lindner, Markus Kramer, Michael Lämmerhofer, J. Sep. Sci., (2022).
https://doi.org/10.1002/jssc.202200268
ACKR3 regulates platelet activation and ischemia-reperfusion tissue injury
Anne-Katrin Rohlfing, Kyra Kolb, Manuel Sigle, Melanie Ziegler, Alexander Bild, Patrick Münzer, Jessica Sudmann, Valerie Dicenta, Tobias Harm, Mailin-Christin Manke, Sascha Geue, Marcel Kremser, Madhumita Chatterjee, Chunguang Liang, Hendrik von Eysmondt, Thomas Dandekar, David Heinzmann, Manina Günter, Saskia von Ungern-Sternberg, Manuela Büttcher, Tatsiana Castor, Stine Mencl, Friederike Langhauser, Katharina Sies, Diyaa Ashour, Mustafa Caglar Beker, Michael Lammerhofer, Stella E. Autenrieth, Tilman E. Schaffer, Stefan Laufer, Paulina Szklanna, Patricia Maguire, Matthias Heikenwalder, Karin Anne Lydia Müller, Dirk M. Hermann, Ertugrul Kilic, Ralf Stumm, Gustavo Ramos, Christoph Kleinschnitz, Oliver Borst, Harald F Langer, Dominik Rath, Meinrad Gawaz, Nat Commun 13, 1823 (2022).
https://doi.org/10.1038/s41467-022-29341-1
Comprehensive profiling of conjugated fatty acid isomers and their lipid oxidation products by two-dimensional chiral RP×RP liquid chromatography hyphenated to UV- and SWATH-MS-detection
Matthias Olfert, Stefanie Bäurer, Marc Wolter, Stephan Buckenmaier, Edmundo Brito-de la Fuente, Michael Laemmerhofer, Anal. Chim. Acta, 1202 (2022) 339667,
https://doi.org/10.1016/j.aca.2022.339667
The molecular basis of rhodomyrtone resistance in Staphylococcus aureus
Li Huang, Carlos Calderón, Sook-Ha Fan, Aparna Ammanath, Xiaoqing Fu, Arif Luqman, Marvin Ullrich, Martin Maier, Anchun Cheng, Michael Lämmerhofer, and Friedrich Götz, mBio, 13 (2022) e03833-21,
https://doi.org/10.1128/mbio.03833-21
High Plasticity of the Amicetin Biosynthetic Pathway in Streptomyces sp. SHP 22-7 Led to the Discovery of Streptcytosine P and Cytosaminomycins F and G and Facilitated the Production of 12F-Plicacetin
Niraj Aryal, Junhong Chen, Oliver Hennrich, Ira Handayani, Markus Kramer, Jan Straetener, Heike Brötz-Oesterhelt, Christian Geibel, Michael Lämmerhofer, Yvonne Mast, Harald Gross, J. Nat. Prod., (2022)
https://doi.org/10.1021/acs.jnatprod.1c01051
Sex-dependent multimodal response profiles to psychosocial stress
Leandra Kuhn, Hannes Noack, Lisa Wagels, Anna Prothmann, Anna Schulik, Ece Aydin, Vanessa Nieratschker, Birgit Derntl, Ute Habel; Cerebral Cortex (2022)
https://doi.org/10.1093/cercor/bhac086
No Evidence for a Role of Oral Contraceptive-Use in Emotion Recognition But Higher Negativity Bias in Early Follicular Women
Kimmig, Ann-Christin Sophie; Bischofberger, Jasper Amadeus; Birrenbach, Annika Dorothea; Drotleff, Bernhard; Lämmerhofer, Michael; Sundström-Poromaa, Inger; Derntl, Birgit, Frontiers in Behavioral Neuroscience, (2022)
https://doi.org/10.3389/fnbeh.2021.773961
Towards enantioselective ultra-high performance liquid chromatography-mass spectrometry-based metabolomics of branched short-chain fatty acids and anteiso-fatty acids under reversed phase conditions using sub-2µm amylose- and cellulose-derived chiral stationary phases
Christian Geibel, Li Zhang, Kristian Serafimov, Harald Gross, Michael Lämmerhofer, Chirality, 34 (2022), 484-497
https://doi.org/10.1002/chir.23413.
Isomer-selective analysis of inositol phosphates with differential isotope labelling by phosphate methylation using liquid chromatography with tandem mass spectrometry
Peng Li, Meinrad Gawaz, Madhumita Chatterjee, Michael Lämmerhofer, Anal. Chim. Acta, 1191 (2022) 339286
https://doi.org/10.1016/j.aca.2021.339286
Enantioselective metabolomics by liquid chromatography-mass spectrometry
Carlos Calderón, Michael Lämmerhofer, J. Pharm. Biomed. Anal., 207 (2022), 114430
https://doi.org/10.1016/j.jpba.2021.114430
Distinct and convergent beneficial effects of estrogen and insulin on cognitive function in healthy young men
Rosemarie Krug, Laura Beier, Michael Lämmerhofer, Manfred Hallschmid, J. Clin. Endocrinol. Metab., 107 (2022), e582-e593
https://doi.org/10.1210/clinem/dgab689
Platelet ACKR3/CXCR7 Favors Anti-Platelet Lipids over an Atherothrombotic Lipidome and Regulates Thrombo-inflammation
Malgorzata Cebo, Kristina Dittrich, Xiaoqing Fu, Mailin-Christin Manke, Frederic Emschermann, Johannes Rheinlaender, Hendrik Von Eysmondt, Nerea Ferreirós, Jessica Sudmann-Innerhofer, Alexander Witte, Lisann Pelzl, Oliver Borst, Tobias Geisler, Dominik Rath, Tamam Bakchoul, Meinrad Gawaz, Tilman E. Schäffer, Michael Lämmerhofer, and Madhumita Chatterjee, Blood, (2022)
https://doi.org/10.1182/blood.2021013097
Enantioselective UHPLC Screening Combined with In Silico Modeling for Streamlined Development of Ultrafast Enantiopurity Assays
Gioacchino Luca Losacco, Heather Wang, Imad A. Haidar Ahmad, Jimmy DaSilva, Alexey A. Makarov, Ian Mangion, Francesco Gasparrini, Michael Lämmerhofer, Daniel W. Armstrong, Erik L. Regalado, Anal. Chem., 94 (2022), 1804-1812
https://doi.org/10.1021/acs.analchem.1c04585
Acute coronary syndrome is associated with a substantial change in the platelet lipidome
Tobias Harm, Andreas Goldschmied, Kristina Dittrich, Madhumita Chatterjee, Kyra Kolb, Tatsiana Castor, Dominik Rath, Michael Lämmerhofer, Meinrad Gawaz, Cardiovasc. Res., (2022).
https://doi.org/10.1093/cvr/cvab238
Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent 9H-pyrimido[4,5-b]indole-based GSK-3β inhibitors
Andreev, Stanislav; Pantsar, Tatu; Tesch, Roberta; Kahlke, Niclas; El-Gokha, Ahmed; Ansideri, Francesco; Grätz, Lukas; Romasco, Jenny; Sita, Giulia; Geibel, Christian; Lämmerhofer, Michael; Tarozzi, Andrea; Knapp, Stefan; Laufer, Stefan; Koch, Pierre, J Med. Chem., 65 (2022), 1283-1301
2021
DoE Optimization Empowers the Automated Preparation of Enantiomerically Pure [18F]Talazoparib and its In Vivo Evaluation as a PARP Radiotracer
Gregory D. Bowden, Sophie Stotz, Johannes Kinzler, Christian Geibel, Michael Lämmerhofer, Bernd J. Pichler, and Andreas Maurer, J. Med. Chem., 64 (2021), 15690-15701
https://doi.org/10.1021/acs.jmedchem.1c00903
Fast accurate quantification of salivary cortisol and cortisone in a large-scale clinical stress study by micro-UHPLC-ESI-MS/MS using a surrogate calibrant approach
Ece Aydin, Bernhard Drotleff, Hannes Noack, Birgit Derntl, Michael Lämmerhofer, J. Chromatogr. B, 1182 (2021), 122939.
https://doi.org/10.1016/j.jchromb.2021.122939
Rapid enantioselective amino acid analysis by ultra-high performance liquid chromatography-mass spectrometry combining 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate derivatization with core-shell quinine carbamate anion exchanger separation
Ryan Karongo, Min Ge, Jeannie Horak, Harald Gross, Michal Kohout, Wolfgang Lindner, Michael Lämmerhofer, J. Chromatogr. Open, 1 (2021) 100004.
https://doi.org/10.1016/j.jcoa.2021.100004
Untargeted UHPLC-ESI-QTOF-MS/MS analysis with targeted feature extraction at precursor and fragment level for profiling of the platelet lipidome with ex vivo thrombin-activation
Malgorzata Cebo, Carlos Calderón Castro, Jörg Schlotterbeck, Meinrad Gawaz, Madhumita Chatterjee, Michael Lämmerhofer, J. Pharm. Biomed. Anal., 205 (2021) 114301.
https://doi.org/10.1016/j.jpba.2021.114301
Enantioselective multiple heart cutting online two-dimensional liquid chromatography-mass spectrometry of all proteinogenic amino acids with second dimension chiral separations in one-minute time scales on a chiral tandem column
Ryan Karongo, Min Ge, Christian Geibel, Jeannie Horak, Michael Laemmerhofer, Anal. Chim. Acta, 1180 (2021) 338858.
https://doi.org/10.1016/j.aca.2021.338858
Controllable organosilane monolayer density of surface bonding using silatranes for thiol functionalization of silica particles for liquid chromatography and validation of microanalytical method for elemental composition determination
Christian Geibel, Johannes Theiner, Marc Wolter, Markus Kramer, Wolfgang Lindner, Michael Lämmerhofer, J. Chromatogr. A, 1653 (2021) 462418.
https://doi.org/10.1016/j.chroma.2021.462418
LC-MS Lipidomik unter Verwendung von SWATH: Globale daten-unabhängige Erzeugung von Massenspektren
Kristina Dittrich, Bernhard Drotleff, Carlos Calderón Castro, Malgorzata Cebo, Xiaoqing Fu, Michael Lämmerhofer
Wiley Analytical Science, June 22 (2021).
https://analyticalscience.wiley.com/do/10.1002/was.000600131
Isomer selective comprehensive lipidomics analysis of phosphoinositides in biological samples by liquid chromatography with data independent acquisition tandem mass spectrometry
Peng Li, Michael Lämmerhofer, Anal. Chem., 93 (2021) 9583–9592.
https://doi.org/10.1021/acs.analchem.1c01751
Chiral metabolomics
C. Calderon, M. Lämmerhofer, in: Rawi Ramautar (Ed.) Advanced Mass Spectrometry-based Analytical Separation Techniques for Probing the Polar Metabolome
Royal Society of Chemistry, London, 2021.
https://doi.org/10.1039/9781839163524
Impurity profiling of siRNA by two-dimensional liquid chromatography-mass spectrometry with quininecarbamate anion-exchanger and ion-pair reversed-phase chromatography
Feiyang Li, Michael Lämmerhofer, J. Chromatogr. A, 1643 (2021) 462065.
https://doi.org/10.1016/j.chroma.2021.462065
Preparation and characterization of poly(3-mercaptopropyl)methylsiloxane functionalized silica particles and their further modification for silver ion chromatography and enantioselective high-performance liquid chromatography
Marc Wolter, Xingyue Chen, Ulrich Woiwode, Christian Geibel, Michael Lämmerhofer, J. Chromatogr. A, 1643 (2021) 462069.
https://doi.org/10.1016/j.chroma.2021.462069
Direct enantioselective gradient reversed-phase ultra-high performance liquid chromatography - tandem mass spectrometry method for 3-hydroxy alkanoic acids in lipopeptides on immobilized 1.6 µm amylose-based chiral stationary phase
Ryan Karongo, Junjing Jiao, Harald Gross, Michael Lämmerhofer, J. Sep. Sci., 44 (2021), 1875-1883
https://doi.org/10.1002/jssc.202100104
Targeted profiling of short-, medium- and long-chain fatty acyl-Coenzyme As in biological samples by phosphate methylation coupled to liquid chromatography–tandem mass spectrometry
Peng Li, Meinrad Gawaz, Madhumita Chatterjee, Michael Lämmerhofer, Anal. Chem., 93 (2021) 4342-4350.
https://doi.org/10.1021/acs.analchem.1c00664
Untargeted LC–MS Lipidomics with Data Independent Acquisition using Sequential Window Acquisition of All Theoretical Fragment-Ion Spectra
Bernhard Drotleff , Carlos Calderón Castro , Malgorzata Cebo , Kristina Dittrich , Xiaoqing Fu , Michael Lämmerhofer, LCGC Europe, 34 (1) (2021) 7–17.
Discovery of Thanafactin A, a New Linear Proline-containing Octa-Lipopeptide from Pseudomonas sp. SH-C52, motivated by genome mining
Norbert Kirchner, Carolina Cano-Prieto, Anna Schulz-Fincke, Michael Gütschow, Nico Ortlieb, Julia Moschny, Timo Niedermeyer, Jeannie Horak, Michael Lämmerhofer, Menno Van der Voort, Jos Raaijmakers, Harald Gross, J. Nat. Prod., 84 (2021), 1, 101–109.
https://doi.org/10.1021/acs.jnatprod.0c01174
Charge variant analysis of protein-based biopharmaceuticals using two-dimensional liquid chromatography hyphenated to mass spectrometry
Simon Jaag, Marina Shirokikh, Michael Lämmerhofer, J. Chromatogr. A, 1636 (2021) 461786.
2020
Discovery and Evaluation of Enantiopure 9H-pyrimido[4,5-b]indoles as Nanomolar GSK-3β Inhibitors with Improved Metabolic Stability
Stanislav Andreev, Tatu Pantsar, Ahmed El-Gokha, Francesco Ansideri, Mark Kudolo, Débora Bublitz Anton, Giulia Sita, Jenny Romasco, Christian Geibel, Michael Lämmerhofer, Márcia Ines Goettert, Andrea Tarozzi, Stefan A. Laufer, Pierre Koch, Int. J. Mol. Sci., 21 (2020), 7823.
https://doi.org/10.3390/ijms21217823
Platelet Lipidomics: A Novel Approach to Assessing Cardiovascular Risk
Madhumita Chatterjee, Michael Lämmerhofer, Tilman Schäffer, Scientia Global, Mar 13, 2020
A Selective Comprehensive Reversed-phase×Reversed-phase 2D-Liquid Chromatography Approach with Multiple Complementary Detectors as Advanced Generic Method for the Quality Control of Synthetic and Therapeutic Peptides
Ryan Karongo, Tohru Ikegami, Dwight R Stoll, Michael Laemmerhofer, J. Chromatogr. A, 1627 (2020) 461430.
https://doi.org/10.1016/j.chroma.2020.461430
Breaking Boundaries with Bioanalysis
Sitting Down With… Michael Lämmerhofer, Professor of Pharmaceutical (Bio-)Analysis, Institute of Pharmaceutical Sciences, University of Tübingen, Germany
Interview in: The Analytical Scientist, 8, 2020; https://theanalyticalscientist.com/fields-applications/breaking-barriers-with-bioanalysis
Micro-UHPLC-MS/MS method for analysis of oxylipins in plasma and platelets
Malgorzata Cebo, Xiaoqing Fu, Meinrad Gawaz, Madhumita Chatterjee, Michael Lämmerhofer
J. Pharm. Biomed. Anal., (2020), 113426
https://doi.org/10.1016/j.jpba.2020.113426
Multiple Heart-Cutting Mixed-mode Chromatography-Reversed-phase 2D-Liquid Chromatography Method for Separation and Mass Spectrometric Characterization of Synthetic Oligonucleotides
Feiyang Li, Xiaoli Su, Stefanie Bäurer, Michael Laemmerhofer,
J. Chromatogr. A, (2020) 461338
https://doi.org/10.1016/j.chroma.2020.461338
Lipid atlas of keratinocytes and betulin effects on its lipidome profiled by comprehensive UHPLC-MS/MS with data independent acquisition using targeted data processing
Carlos Calderón, Lara Rubarth, Malgorzata Cebo, Irmgard Merfort, Michael Lämmerhofer
Proteomics, 20 (2020) 1900113.
https://doi.org/10.1002/pmic.201900113
Lipidomic profiling of non-mineralized dental plaque and biofilm by untargeted UHPLC-QTOF-MS/MS and SWATH acquisition
Bernhard Drotleff, Simon Roth, Kerstin Henkel, Jörg Schlotterbeck, Merja Neukamm, Michael Laemmerhofer
Analytical and Bioanalytical Chemistry, 412 (2020) 2303–2314.
https://doi.org/10.1007/s00216-019-02364-2
Fragment-based Design of Zwitterionic, Strong Cation- and Weak Anion-Exchange Type Mixed-mode Liquid Chromatography Ligands and their Chromatographic Exploration
Martina Ferri, Stefanie Bäurer, Andrea Carotti, Marc Wolter, Belal Alshaar, Johannes Theiner, Tohru Ikegami, Caroline West, Michael Lämmerhofer
J. Chromatogr. A, 1621 (2020), 461075.
https://doi.org/10.1016/j.chroma.2020.461075
Thiol-ene photo-click immobilization of a chiral chromatographic ligand on silica particles
Christian Geibel, Kristina Dittrich, Marc Wolter, Michael Lämmerhofer
J. Chromatogr. A, 1622 (2020) 461133
https://doi.org/10.1016/j.chroma.2020.461133
Enantioselective UHPLC-MS/MS method based on sub-2µm particle polysaccharide column for chiral separation of oxylipins and its application for the analysis of auto-oxidized fatty acids and platelet releasates
Malgorzata Cebo, Xiaoqing Fu, Meinrad Gawaz, Madhumita Chatterjee, Michael Lämmerhofer
J. Chromatogr. A, 1624 (2020) 461206
https://doi.org/10.1016/j.chroma.2020.461206
Separation of Carbohydrate Isomers and Anomers on Poly-N-(1H-tetrazole-5-yl)-methacrylamide-bonded Stationary Phase by Hydrophilic Interaction Chromatography as well as Determination of Anomer Interconversion Energy Barriers
Xiaoqing Fu, Malgorzata Cebo, Tohru Ikegami, Michael Lämmerhofer
J. Chromatogr. A, 1620 (2020), 460981
https://doi.org/10.1016/j.chroma.2020.460981
Cinchona-based zwitterionic stationary phases: Exploring retention and enantioseparation mechanisms in supercritical fluid chromatography with a fragmentation approach
Adrien Raimbault, Cam Mai Anh Ma, Martina Ferri, Stefanie Bäurer, Pascal Bonnet, Stéphane Bourg, Michael Lämmerhofer, Caroline West
J. Chromatogr. A, 1612 (2020), 460689.
https://doi.org/10.1016/j.chroma.2019.460689
Simultaneous targeted and untargeted UHPLC-ESI-MS/MS method with data-independent acquisition for quantification and profiling of (oxidized) fatty acids released upon platelet activation by thrombin
Malgorzata Cebo, Jörg Schlotterbeck, Meinrad Gawaz, Madhumita Chatterjee, Michael Lämmerhofer
Anal. Chim. Acta, 1094 (2020) 57-69.
https://doi.org/10.1016/j.aca.2019.10.005
Mixed-mode Chromatography Characteristics of Chiralpak ZWIX(+) and ZWIX(-) and Elucidation of their Chromatographic Orthogonality for LC×LC Application
Stefanie Bäurer, Martina Ferri, Andrea Carotti, Stefan Neubauer, Roccaldo Sardella, Michael Lämmerhofer
Anal. Chim. Acta, 1093 (2020) 168-179.
https://doi.org/10.1016/j.aca.2019.09.068
Retention Characteristics of Poly(N-(1H-tetrazole-5-yl)-methacrylamide)-bonded Stationary Phase in Hydrophilic Interaction Chromatography
Xiaoqing Fu, Malgorzata Cebo, Tohru Ikegami, Michael Lämmerhofer
J. Chromatogr. A, 1609 (2020), 460500.
2019
In-situ photopolymerized polyhedral oligomeric silsesquioxane-derived monolithic capillary columns with quinidine functionality for enantioseparation by nano-liquid chromatography
Siyao Liu, Xinyue Fu, Ronny Löffler, Michael Lämmerhofer
Electrophoresis, 40 (2019), 3132-3139.
https://doi.org/10.1002/elps.201900316
Racemization without deamidation: Effect of racemization conditions on 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate tagged amino acids
Jeannie Horak, Michael Lämmerhofer.
J. Chromatogr. A, 1604 (2019), 460492.
https://doi.org/10.1016/j.chroma.2019.460492
Comprehensive Lipidomics of Mouse Plasma using Class-Specific Surrogate Calibrants and SWATH Acquisition for Large-Scale Lipid Quantification in Untargeted Analysis
Bernhard Drotleff, Julia Illison, Jörg Schlotterbeck, Robert Lukowski, Michael Lämmerhofer
Anal. Chim. Acta, 1086 (2019), 90-102.
https://doi.org/10.1016/j.aca.2019.08.030
Guidelines for Selection of Internal Standard-based Normalization Strategies in Untargeted Lipidomic Profiling by LC-HR-MS/MS
Bernhard Drotleff, Michael Lämmerhofer
Anal. Chem., 2019, 91, 15, 9836-9843.
https://doi.org/10.1021/acs.analchem.9b01505
Evaluation of superficially porous particle based zwitterionic chiral ion exchangers against fully porous particle benchmarks for enantioselective ultra-high performance liquid chromatography
Christian Geibel, Kristina Dittrich, Ulrich Woiwode, Michal Kohout, Tong Zhang, Wolfgang Lindner, Michael Lämmerhofer
J. Chromatogr. A, 1603 (2019), 130-140.
https://doi.org/10.1016/j.chroma.2019.06.026
Derivatize, Racemize and Analyze - an Easy and Simple Procedure for Chiral Amino Acid Standard Preparation for Enantioselective Metabolomics
Jeannie Horak, Michael Lämmerhofer
Anal. Chem., 2019, 91, 12, 7679-7689.
https://doi.org/10.1021/acs.analchem.9b00666
Functionalized gold nanoparticles for sample preparation: A review
Siyao Liu, Michael Lämmerhofer
Electrophoresis, 40 (2019), 2438-2461.
https://doi.org/10.1002/elps.201900111
Chiral separation of underivatized and 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate derivatized amino acids using zwitterionic quinine and quinidine type ZWIX columns by liquid chromatography - high-resolution mass spectrometry
Jeannie Horak, Michael Lämmerhofer
J. Chromatogr. A, 1596 (2019), 69-78.
https://doi.org/10.1016/j.chroma.2019.02.060
Stable-bond reversed-phase/weak anion-exchange mixed-mode stationary phase obtained by simultaneous functionalization and crosslinking of a poly(3-mercaptopropyl)methylsiloxane-film on vinyl silica via thiol-ene double click reaction
Stefanie Bäurer, Aleksandra Zimmermann, Ulrich Woiwode, Orlando Sánchez-Muñoz, Markus Kramer, Jeannie Horak, Michael Lämmerhofer
J. Chromatogr. A, 1593 (2019) 110-118.
https://doi.org/10.1016/j.chroma.2019.01.078
In-situ photopolymerized C4-functionalized organosilicon monoliths for reversed-phase protein separation in nano-liquid chromatography.
Çiğdem Kip, Siyao Liu, Xinhue Fu, Ali Tuncel, Michael Lämmerhofer
Talanta, 198 (2019) 330-336.
https://doi.org/10.1016/j.talanta.2019.01.116
A combined Targeted/Untargeted LC-MS/MS-based Screening Approach for Mammalian Cell Lines Treated with Ionic Liquids: Toxicity Correlates with Metabolic Profile
Corinna Sanwald, Alexandra Robciuc, Suvi-Katriina Ruokonen, Susanne K. Wiedmer, Michael Lämmerhofer
Talanta, 197 (2019) 472-481.
https://doi.org/10.1016/j.talanta.2019.01.054
Discovery of the Cyclic Lipopeptide Gacamide A by Genome Mining and Repair of the defective GacA-Regulator in Pseudomonas fluorescens Pf0-1
Gahzaleh Jahanshah, Heike Gerhardt, Zoltán Pataj, Michael Lämmerhofer, Isabelle Pianet, Markus Nett, Michaele Josten, Hans-Georg Sahl, Mark W. Silby, Joyce E. Loper, Harald Gross
J. Nat. Prod., 2019, 82, 2, 301-308.
https://doi.org/10.1021/acs.jnatprod.8b00747
Guidelines for tuning the macropore structure of monolithic columns for high-performance liquid chromatography
José Luís Dores-Sousa, Alejandro Fernández-Pumarega, Jelle De Vos, Michael Lämmerhofer, Gert Desmet, Sebastiaan Eeltink,
J. Sep. Sci., 42 (2019) 522-533.
https://doi.org/10.1002/jssc.201801092
Quantitative analysis of chemoresistance-inducing fatty acid in food supplements using UHPLC-ESI-MS/MS
Jörg Schlotterbeck, Malgorzata Cebo, Agnes Kolb, Michael Lämmerhofer
Anal. Bioanal. Chem., 411 (2019) 479-491.
https://doi.org/10.1007/s00216-018-1468-x
Comparison of simple monophasic versus classical biphasic extraction protocols for comprehensive UHPLC-MS/MS lipidomics analysis of Hela cells
Carlos Calderón, Corinna Sanwald, Jörg Schlotterbeck, Bernhard Drotleff, Michael Lämmerhofer
Anal. Chim. Acta, 1048 (2019) 66-74.
https://doi.org/10.1016/j.aca.2018.10.035
Protein A- and Protein G-Gold Nanoparticle Bioconjugates as Nano-Immunoaffinity Platform for human IgG Depletion in Plasma and Antibody Extraction from Cell Culture Supernatant
Siyao Liu, Elisabeth Haller, Jeannie Horak, Marlene Brandstetter, Thomas Heuser, Michael Lämmerhofer
Talanta, 194 (2019) 664-672.
https://doi.org/10.1016/j.talanta.2018.10.079
Simultaneous separation of water- and fat-soluble vitamins by selective comprehensive hilic × rplc (high-resolution sampling) and active solvent modulation
Stefanie Bäurer, Wenkai Guo, Stefan Polnick, Michael Lämmerhofer
Chromatographia, 82 (2019) 167-180.
https://doi.org/10.1007/s10337-018-3615-0
Comprehensive MS/MS profiling by UHPLC-ESI-QTOF-MS/MS using swath data-independent acquisition for the study of platelet lipidomes in coronary artery disease
Jörg Schlotterbeck, Madhumita Chatterjee, Meinrad Gawaz, Michael Lämmerhofer
Anal. Chim. Acta, 1046 (2019) 1-15.
2018
Free fatty acid profiling in marine algae extract by LC‐MS/MS and isolation as well as quantification of the ω‐3 fatty acid hexadeca‐4,7,10,13‐tetraenoic acid
Jörg Schlotterbeck, Agnes Kolb, Michael Lämmerhofer
J. Sep. Sci., 41 (2018) 4286-4295.
https://doi.org/10.1002/jssc.201800780
Comparison of small size fully porous particles and superficially porous particles of chiral anion-exchange type stationary phases in ultra-high performance liquid chromatography: Effect of particle and pore size on chromatographic efficiency and kinetic performance
Kristina Schmitt, Ulrich Woiwode, Michal Kohout, Tong Zhang, Wolfgang Lindner, Michael Lämmerhofer
J. Chromatogr. A, 1569 (2018) 149-159.
https://doi.org/10.1016/j.chroma.2018.07.056
Zwitterionic codeine-derived methacrylate monoliths for enantioselective capillary electrochromatography of chiral acids and chiral bases
Enrique Javier Carrasco-Correa, Martina Ferri, Ulrich Woiwode, Yubo Ma, José Manuel Herrero-Martínez, Guillermo Ramis-Ramos, Wolfgang Lindner, Michael Lämmerhofer
Electrophoresis, 39 (2018) 2558-2565.
https://doi.org/10.1002/elps.201800126
Imaging peptide and protein chirality via amino acid analysis by chiral × chiral two-dimensional correlation liquid chromatography
Ulrich Woiwode, Roland Johann Reischl, Stephan Buckenmaier, Wolfgang Lindner, and Michael Lämmerhofer
Anal. Chem., 2018, 90 (13), pp 7963–7971
https://doi.org/10.1021/acs.analchem.8b00676
Complementary enantioselectivity profiles of chiral cinchonan carbamate selectors with distinct carbamate residues and their implementation in enantioselective two-dimensional high-performance liquid chromatography of amino acids
Ulrich Woiwode, Martina Ferri, Norbert M Maier, Wolfgang Lindner, Michael Laemmerhofer
J. Chromatogr. A, 1558 (2018) 29-36.
https://doi.org/10.1016/j.chroma.2018.04.061
N-Propyl-N'-2-pyridylurea-modified silica as mixed-mode stationary phase with moderate weak anion exchange capacity and pH-dependent surface charge reversal
Stefanie Baeurer, Stefan Polnick, Orlando L Sanchez-Munoz, Markus Kramer, Michael Laemmerhofer
J. Chromatogr. A, 1560 (2018) 45-54.
https://doi.org/10.1016/j.chroma.2018.05.012
Enantioselective multiple heartcut two-dimensional ultra-high-performance liquid chromatography method with a Coreshell chiral stationary phase in the second dimension for analysis of all proteinogenic amino acids in a single run
Ulrich Woiwode, Stefan Neubauer, Wolfgang Lindner, Stephan Buckenmaier, Michael Lämmerhofer
J. Chromatogr. A, 1562 (2018) 69-77.
https://doi.org/10.1016/j.chroma.2018.05.062
Quantification of Steroid Hormones in Plasma Using a Surrogate Calibrant Approach and UHPLC-ESI-QTOF-MS/MS with SWATH-Acquisition Combined with Untargeted Profiling
B. Drotleff, M. Hallschmid, M. Lämmerhofer
Anal. Chim. Acta, 1022 (2018) 70-80.
https://doi.org/10.1016/j.aca.2018.03.040
Insulin and Estrogen Independently and Differentially Reduce Macronutrient Intake in Healthy Men
R. Krug, L. Mohwinkel, B. Drotleff, J. Born, M. Hallschmid
J. Clin. Endocrinol. Metab, 103 (2018) 1393-1401
https://doi.org/10.1210/jc.2017-01835
Chiral Separation of disease biomarkers with 2-hydroxycarboxylic acid structure
Carlos Calderon, Cristina Santi, Michael Lämmerhofer
J. Sep. Sci., 41 (2018) 1224-1231
https://doi.org/10.1002/jssc.201701243
Correlation between ionic liquid cytotoxicity and liposome-ionic liquid interactions.
Suvi-Katriina Ruokonen, Corinna Sanwald, Alexandra Robciuc, Sami Hietala, Antti H. Rantamäki, Joanna Witos, Alistair W. T. King, Michael Lämmerhofer, Susanne K. Wiedmer
Chem. Eur .J., 24 (2018) 2669 –2680
http://dx.doi.org/10.1002/chem.201704924.
Response Surface Methodology for the Determination of the Design Space of Enantiomeric Separations on Cinchona-based Zwitterionic Chiral Stationary Phases by High Performance Liquid chromatography.
Rasha Sayed Hanafi, Michael Lämmerhofer
J. Chromatogr. A, 1534 (2018) 55-63
https://doi.org/10.1016/j.chroma.2017.12.044
Optimization of surface modification process of crosslinked polythiol-coated chiral stationary phases synthesized by two-step thiol-ene click reaction
Kristina Schmitt, Michael Lämmerhofer
J. Sep. Sci., 41 (2018) 1338–1345
2017
Sub-minute Separations in Enantioselective Ultra High-Performance Liquid Chromatography with Superficially Porous Chiral Stationary Phases
Ulrich Woiwode, Stefan Neubauer, Mike Kaupert, Wolfgang Lindner, Michael Lämmerhofer
Chrom+Food FORUM, 09 (2017)
Accurate and Reliable Quantification of the Protein Surface Coverage on Protein-Functionalized Nanoparticles
Siyao Liu, Jeannie Horak, Markus Höldrich, Michael Lämmerhofer
Anal. Chim. Acta, 989 (2017) 29-37.
http://dx.doi.org/10.1016/j.aca.2017.08.004
Design, Synthesis, and Biological Evaluation of Novel Type I1/2 p38α MAP Kinase Inhibitors with Excellent Selectivity, High Potency, and Prolonged Target Residence Time by Interfering with the R-Spine
Niklas M. Walter, Heike K. Wentsch, Mike Bührmann, Silke M. Bauer, Eva Döring, Svenja Mayer-Wrangowski, Adrian Sievers-Engler, Nicole Willemsen-Seegers, Guido Zaman, Rogier Buijsman, Michael Lämmerhofer, Daniel Rauh, and Stefan A. Laufer
J. Med. Chem., 60 (2017) 8027–8054.
http://dx.doi.org/10.1021/acs.jmedchem.7b00745
Trends in Enantioselective High-Performance Liquid Chromatography
Ulrich Woiwode, Stefan Neubauer, Mike Kaupert, Wolfgang Lindner, Michael Lämmerhofer
Special Issue on Recent Developments in HPLC and UHPLC (Ed. Deirdre Cabooter), Supplement to LCGC Europe / LCGC North America, June 01, 2017, Volume 30, Issue 6, 34-42.
http://www.chromatographyonline.com/trends-enantioselective-high-performance-liquid-chromatography
Preparation of Mach-Zehnder interferometric photonic biosensors by inkjet printing technology
Florian Strasser; Eva Melnik; Paul Muellner; Pilar Jiménez-Meneses; Magdalena Nechvile; Guenther Koppitsch; Peter Lieberzeit; Michael Laemmerhofer; Rudolf Heer; Rainer Hainberger
Proc. SPIE 10231, Optical Sensors 2017, 102312H (May 16, 2017)
http://dx.doi.org/10.1117/12.2267156
Trisubstituted imidazoles with a rigidized hinge binding motif act as single digit nM inhibitors of clinically relevant EGFR L858R/T790M and L858R/T790M/C797S mutants: An example of target hopping
Michael Juchum, Marcel Günther, Eva Doering, Adrian Sievers-Engler, Michael Lämmerhofer, Stefan A. Laufer
J. Med. Chem., 60 (2017) 4636-4656.
http://dx.doi.org/10.1021/acs.jmedchem.7b00178
Surface-anchored counterions on weak chiral anion-exchangers accelerate separations and improve their compatibility for mass-spectrometry-hyphenation
Ulrich Woiwode, Adrian Sievers-Engler, Aleksandra Zimmermann, Wolfgang Lindner, Orlando L. Sánchez-Muñoz, Michael Lämmerhofer
J. Chromatogr. A, 1503 (2017) 21-31.
http://dx.doi.org/10.1016/j.chroma.2017.04.054
Gold Nanoparticle-Based Immobilized Enzyme Reactors Straightforward and Accelerated Sample Preparation in Protein and Biopharmaceuticals Analysis
Siyao Liu, Markus Höldrich, Helmut Hinterwirth, Michael Lämmerhofer
Chrom+Food FORUM, 04 (2017) 12-15.
In-situ Functionalized Monolithic Polysiloxane-Polymethacrylate Composite Materials from Polythiol-Ene Double Click Reaction in Capillary Column Format for Enantioselective Nano-HPLC
Marc Wolter, Michael Lämmerhofer,
J. Chromatogr. A, 1497 (2017) 172-179.
http://dx.doi.org/10.1016/j.chroma.2017.03.070
Regulation of oxidized platelet lipidome: implications for coronary artery disease
Madhumita Chatterjee, Dominik Rath, Jörg Schlotterbeck, Johannes Rheinlaender, Britta Walker-Allgaier, Nada Alnaggar, Monika Zdanyte, Iris Müller, Oliver Borst, Tobias Geisler, Tilman E. Schäffer, Michael Lämmerhofer and Meinrad Gawaz
Eur Heart J., 38 (2017) 1993-2005.
http://dx.doi.org/10.1093/eurheartj/ehx146
Selective Targeting of G-Quadruplex Structures by a Benzothiazole-Based Binding Motif
Ina Buchholz, Beatrice Karg, Jonathan Dickerhoff, Adrian Sievers-Engler, Michael Lämmerhofer, Klaus Weisz
Chem. Eur. J., 23 (2017) 5814-5823.
http://dx.doi.org/10.1002/chem.201700298
Papain-functionalized Gold Nanoparticles as Heterogeneous Biocatalyst for Bioanalysis and Biopharmaceuticals Analysis
Siyao Liu, Markus Höldrich, Adrian Sievers-Engler, Jeannie Horak, Michael Lämmerhofer
Anal. Chim. Acta, 963 (2017) 33-43,
http://dx.doi.org/10.1016/j.aca.2017.02.009
Taylor Dispersion Analysis, Resonant Mass Measurement and Bioactivity of Pepsin-Coated Gold Nanoparticles
Markus Höldrich, Siyao Liu, Markus Epe, Michael Lämmerhofer
Talanta, 167 (2017) 67–74
http://dx.doi.org/10.1016/j.talanta.2017.02.010
Chiral Separation of Short Chain Aliphatic Hydroxycarboxylic Acids on Cinchonan Carbamate based Weak Chiral Anion Exchangers and Zwitterionic Chiral Ion Exchangers
Carlos Calderón, Michael Lämmerhofer
J. Chromatogr. A, 1487 (2017) 194–200
http://dx.doi.org/10.1016/j.chroma.2017.01.060
Tri‐ and Tetra‐substituted Pyridinylimidazoles as Covalent Inhibitors of c‐Jun N‐Terminal Kinase 3
Felix Muth, Ahmed El-Gokha, Francesco Ansideri, Michael Eitel, Eva Döring, Adrian Sievers-Engler, Andreas Lange, Frank M. Boeckler, Michael Laemmerhofer, Pierre Koch, and Stefan A. Laufer
J. Med. Chem., 60 (2017) 594–607
2016
Surface Modification of Integrated Optical MZI Sensor Arrays Using Inkjet Printing Technology
Eva Melnik, Florian Strasser, Paul Muellner, Rudolf Heer, Giorgio C. Mutinati, Guenther Koppitsch, Peter Lieberzeit, Michael Laemmerhofer, Rainer Hainberger
Procedia Engineering, 168 (2016) 337–340.
http://dx.doi.org/10.1016/j.proeng.2016.11.113.
Insect adhesion secretions: Similarities and dissimilarities in hydrocarbon profiles of tarsi and corresponding tibiae
Heike Gerhardt, Oliver Betz, Klaus Albert, Michael Lämmerhofer
J. Chem. Ecol., 42(2016), 725-738
http://dx.doi.org/10.1007/s10886-016-0718-7
Local functionalization of CMOS-compatible Si3N4 Mach-Zehnder interferometers with printable functional polymers
Eva Melnik, Paul Muellner, Giorgio Mutinati, Guenther Koppitsch, Franz Schrank, Rainer Hainberger, Michael Laemmerhofer
Sensors und Actuators B, Chemical, 236 (2016) 1061–1068
DOI: 10.1016/j.snb.2016.05.121
Effect of Ionic Liquids on Zebrafish (Danio rerio) Viability, Behavior, and Histology; Correlation between Toxicity and Ionic Liquid Aggregation.
Suvi-Katriina Ruokonen, Corinna Sanwald, Maria Sundvik, Stefan Polnick, Kashmira Vyavaharkar, Filip Duša, Ashley J. Holding, Alistair W. T. King, Ilkka Kilpeläinen, Michael Lämmerhofer, Pertti Panula, and Susanne K. Wiedmer
Environmental Science & Technology, 50 (2016), 7116–7125
Gold nanoparticle-conjugated pepsin for efficient solution-like heterogeneous biocatalysis in analytical sample preparation protocols
Markus Höldrich, Adrian Sievers-Engler, Michael Lämmerhofer
Anal. Bioanal. Chem., 408 (2016), 5415–5427
DOI: 10.1007/s00216-016-9657-y
Chiral Separation of 2-Hydroxyglutaric Acid on Cinchonan Carbamate based Weak Chiral Anion Exchangers by High-Performance Liquid Chromatography-Charged Aerosol Detector
Carlos Calderon, Jeannie Horak, Michael Lämmerhofer
J. Chromatogr. A, 1467 (2016) 239-245
DOI: 10.1016/j.chroma.2016.05.042
Surface-crosslinked poly(3-mercaptopropyl)methylsiloxane-coatings on silica as new platform for low-bleed mass spectrometry-compatible functionalized stationary phases synthesized via thiol-ene click reaction
Aleksandra Zimmermann, Jeannie Horak, Adrian Sievers-Engler, Corinna Sanwald, Wolfgang Lindner, Markus Kramer, Michael Lämmerhofer
J. Chromatogr. A, 1436 (2016) 73–83
DOI: 10.1016/j.chrima.2016.01.058
Peptide analysis: Stereoselective ion exchangers as complementary option to HILIC and to RP chromatography
Tong Zhang, Emilie Holder, Pilar Franco, Michael Lämmerhofer, Adrian Sievers-Engler, Heike Gerhardt, Harald Gross, Wolfgang Lindner
LCGC, 29 (3) (2016) 112-128
Human IgG detection in serum on polymer based Mach-Zehnder interferometric biosensors
Eva Melnik, Roman Bruck, Paul Müllner, Thomas Schlederer , Rainer Hainberger, Michael Lämmerhofer
J. Biophotonics, 9 (2016) 218-223
Preparation of fluorescent labeled gentamicin as biological tracer and its characterization by liquid chromatography and high resolution mass spectrometry
U. Woiwode, A. Sievers-Engler, M. Lämmerhofer
J. Pharm. Biomed. Anal.,121, (2016) 307–315
DOI: 10.1016/j.jpba.2015.12.053
Methods for the comprehensive structural elucidation of constitution and stereochemistry of lipopeptides
Heike Gerhardt, Adrian Sievers-Engler, Ghazaleh Jahanshah, Zoltán Pataj, Federica Ianni, Harald Gross, Wolfgang Lindner, Michael Lämmerhofer
J. Chromatogr. A, 1428 (2016) 280–291
DOI: 10.1016/j.chroma.2015.05.065
Quinine-based zwitterionic chiral stationary phase as complementary tool for peptide analysis: Mobile phase effects on enantio- and stereoselectivity of underivatized oligopeptides
Federica Ianni, Roccaldo Sardella, Andrea Carotti, Benedetto Natalini, Wolfgang Lindner, Michael Lämmerhofer
Chirality, 28 (2016) 5–16
Mastering analytical challenges for the characterization of pentacyclic triterpene mono and diesters of Calendula officinalis flowers by non-aqueous C30 HPLC and hyphenation with APCI-QTOF-MS
Christoph Nicolaus, Adrian Sievers-Engler, Renato Murillo, Michele D’Ambrosio, Michael Lämmerhofer, Irmgard Merfort
J. Pharm. Biomed. Anal., 118 (2016) 195–205
2015
Structural and Biophysical Evaluation of the Applicability of Halogen Bonding in Molecular Design - Targeting the Gatekeeper MET146 of C-Jun N-terminal Kinase 3 (JNK3)
Andreas Lange, Marcel B. Günther, Felix Büttner, Markus O. Zimmermann, Johannes Heidrich, Susanne Hennig, Christoph Schall, Adrian Sievers-Engler, Francesco Ansideri, Pierre Koch, Michael Lämmerhofer, Thilo Stehle, Stefan A. Laufer, Frank M. Böckler
J. Am. Chem. Soc., 137 (2015) 14640-14652
Review: Developments in hyphenation of isoelectric focusing with mass spectrometry
Jens Hühner, Michael Lämmerhofer, Christian Neusüß
Electrophoresis, 36 (2015) 2670-2686
Molecular Recognition and Visual Detection of G-Quadruplexes by a Dicarbocyanine Dye
Beatrice Karg, Andrea Funke, Anna Ficht, Adrian Sievers-Engler, Michael Lämmerhofer, Klaus Weisz
Chemistry- A European Journal, 21 (2015) 13802-13811
Investigating insect adhesion secretions by gas chromatography – mass spectrometry
Klaus Albert, Heike Gerhardt, Michael Lämmerhofer
J Chromatograph Separat Techniq, (2015) S1
Surface charge fine tuning of reversed-phase/weak anion-exchange type mixed-mode stationary phases for milder elution conditions
Aleksandra Zimmermann, Jeannie Horak, Orlando L. Sánchez-Muñoz, Michael Lämmerhofer
J. Chromatogr. A, 1409 (2015) 189-200
DOI: 10.1016/j.chroma.2015.07.036
Digging into Biomarkers of Oxidative Stress: Hyphenated chromatography techniques enable the selection of representative biomarkers of oxidative stress – and help resolve the huge complexity of lipid oxidation products
Michael Lämmerhofer
The Analytical Scientist, July 20th, 2015| Issue #0715 (Article # 302).
Selective Sample Preparation by Carbonyl-Tagging and Nanoparticle-Based Enrichment for LC-MS/MS Analysis of Carbonylated Phospholipids as Biomarkers of Oxidative Stress
Michael Lämmerhofer, Elisabeth Haller, Wolfgang Lindner
ChromFood Forum, 06 (2015) 9-13
Staying power: Adhesives modeled on insect secretions
Heike Gerhardt and Michael Lämmerhofer
q&more 01.15, English version
Starke Haftkraft: Klebstoffe nach dem Vorbild von Insektensekreten
Heike Gerhardt, Michael Lämmerhofer
q&more 01.15, Deutsche Ausgabe
Phosphatidyl choline covalently linked to a methacrylate-based monolith as stationary phase for capillary liquid chromatography
Dana Moravcová, Enrique Javier Carrasco-Correa, Josef Planeta, Michael Lämmerhofer, Susanne K. Wiedmer
J. Chromatogr. A, 1402 (2015) 27–35
DOI: 10.1016/j.chroma.2015.05.004
The novel lipopeptide poaeamide of the endophyte Pseudomonas poae RE*1-1-14 is involved in pathogen suppression and root colonization
Christin Zachow, Ghazaleh Jahanshah, Irene de Bruijn, Chunxu Song, Federica Ianni, Zoltán Pataj, Heike Gerhardt, Isabelle Pianet, Michael Lämmerhofer, Gabriele Berg, Harald Gross, Jos M. Raaijmakers
Molecular Plant-Microbe Interactions, 28 (2015) 800-810
DOI: 10.1094/MPMI-12-14-0406-R
New insights into novel inhibitors against deoxyhypusine hydroxylase from plasmodium falciparum: Compounds with an iron chelating potential
Imke von Koschitzky, Heike Gerhardt, Michael Lämmerhofer, Michal Kohout, Matthias Gehringer, Stefan Laufer, Mario Pink, Simone Schmitz-Spahnke, Christina Strube, Annette Kaiser
Amino Acids, 47 (2015) 1155-1166
DOI: 10.1007/s00726-015-1943-z
Contact Solid-phase Microextraction with Uncoated Glass and Polydimethylsiloxane-coated Fibers versus Solvent Sampling for the Determination of Hydrocarbons in Adhesion Secretions of Madagascar Hissing Cockroaches Gromphadorrhina portentosa (Blattodea) by Gas Chromatography-Mass Spectrometry
Heike Gerhardt, Christian Schmitt, Oliver Betz, Klaus Albert, Michael Lämmerhofer
J. Chromatography A, 1388 (2015) 24-35
DOI: 10.1016/j.chroma.2015.02.027
Impact of amphiphilic biomass-dissolving ionic liquids on biological cells and liposomes
Suvi-Katriina Mikkola, Alexandra Robciuc, Jana Lokajova, Ashley Holding, Michael Lämmerhofer, Ilkka Kilpeläinen, Juha Holopainen, Alistair King, Susanne Wiedmer
Environmental Science & Technology, 49 (2015) 1870-1878
Quantification of riboflavin, flavin mononucleotide and flavin adenine dinucleotide in mammalian model cells by CE with LED-induced fluorescence detection
Jens Hühner, Álvaro Ingles-Prieto, Christian Neusüß, Michael Lämmerhofer, Harald Janovjak
Electrophoresis, 36 (2015) 518-525
Gold Nanoparticle – Antibody Bioconjugates for Specific Extraction and subsequent LC-MS/MS Analysis of Malondialdehyde-modified LDL as Biomarker for Atherosclerotic Risk Assessment
Elisabeth Haller, Wolfgang Lindner, Michael Lämmerhofer
Anal. Chim. Acta, 857 (2015) 53-63
DOI: 10.1016/j.aca.2014.12.024
Analysis of Chemical Profiles of Insect Adhesion Secretions by Gas Chromatography-Mass Spectrometry
Manuela Reitz, Heike Gerhardt, Christian Schmitt, Oliver Betz, Klaus Albert, Michael Lämmerhofer
Anal. Chim. Acta, 854 (2015) 47-60
2014
Mixed-mode (RP/WAX) stationäre Phasen – Verbesserung der Selektivität bei der Reinigung und Analyse synthetischer Oligonukleotide für die Gentherapie
Aleksandra Zimmermann, Jeannie Horak, Michael Lämmerhofer
chrom+food FORUM, 09 (2014) 57-59
Polymethacrylate monoliths with immobilized poly-3-mercaptopropyl methylsiloxane film for high-coverage surface functionalization by thiol-ene click reaction
Enrique J. Carrasco Correa, Guillermo Ramis Ramos, José Manuel Herrero-Martínez, Michael Lämmerhofer
J. Chromatogr. A, 1367 (2014) 132-130
DOI: 10.1016/j.chroma.2014.09.066
Chemical Recognition of Oxidation-Specific Epitopes in Low Density Lipoproteins by a Nanoparticle based Concept for Trapping, Enrichment and LC-MS/MS Analysis of Oxidative Stress Biomarkers
ElisabethHaller, Gerald Stübiger, Daniel Lafitte, Wolfgang Lindner, Michael Lämmerhofer
Anal. Chem., 86(19) (2014) 9954–9961
Liquid chromatographic enantiomer separation with special focus on zwitterionic chiral ion-exchangers
Michael Lämmerhofer
Anal. Bioanal. Chem., 406 (2014) 6095-6103
DOI: 10.1007/s00216-014-7930-5
Synthetic oligonucleotide separation by mixed-mode reversed-phase/weak anion-exchange liquid chromatography
Aleksandra Zimmermann, Roberto Greco, Isabel Walker, Jeannie Horak, Alberto Cavazzini, Michael Lämmerhofer
J. Chromatogr. A, 1354 (2014) 43-55
DOI: 10.1016/j.chroma.2014.05.048
Target evaluation of deoxyhypusine synthase from Theileria parva the neglected animal parasite and its relationship to Plasmodium
James T. Njuguna, Imke von Koschitzky, Heike Gerhardt, Michael Lämmerhofer, Ali Choucry, Mario Pink, Simone Schmitz-Spahnke, Mohammed A. Bakheit, Christina Strube, Annette Kaiser
Bioorg. Med. Chem., 22 (2014) 4338–4346
DOI: 10.1016/j.bmc.2014.05.007
Mucin-based Stationary Phases as Tool for the Characterization of Drug - Mucus Interaction
Andrea F.G. Gargano, Michael Lämmerhofer, Hans Lönn, Peter Schoenmakers, Tomas Leek
J. Chromatogr. A., 1351 (2014) 70-81
DOI: 10.1016/j.chroma.2014.05.031
Ligand-Receptor Binding Increments in Enantioselective Liquid Chromatography
Adrian Sievers-Engler, Wolfgang Lindner, Michael Lämmerhofer
J. Chromatogr. A, 1363 (2014) 79-88
DOI: 10.1016/j.chroma.2014.04.077
Direct enantioseparation of underivatized aliphatic 3-hydroxyalkanoic acids with a quinine-based zwitterionic chiral stationary phase
Federica Ianni, Zoltán Pataj, Harald Gross, Roccaldo Sardella, Benedetto Natalini, Wolfgang Lindner, Michael Lämmerhofer
J. Chromatogr. A, 1363 (2014) 101-108
DOI: 10.1016/j.chroma.2014.03.060
Trendbericht: Analytische Chemie 2012/2013
Michael Lämmerhofer, Jürgen Popp, Suhang He, Werner Nau, Kerstin Leopold, Christine Kranz, Jürgen W. Einax, Boris Mizaikoff
Nachrichten aus der Chemie, 62(4) (2014) 407-414
Extract from gum resin of boswellia serrata decreases IA2-antibody in a patient with “Late onset Autoimmune Diabetes of the Adult” (LADA)
E. Schrott, S. Laufer, M. Lämmerhofer, H.P.T. Ammon
Phytomedicine, 21(6) (2014) 786
DOI: 10.1016/j.phymed.2014.02.004
Streptavidin binding as model to characterize thiol-ene chemistry based polyamine surfaces for reversible photonic protein biosensing
Eva Melnik, Paul Muellner, Ole Bethge, Emmerich Bertagnolli, Rainer Hainberger, Michael Lämmerhofer
Chem. Commun., 50(19) (2014) 2424-2427
Simultaneous quantification of mefloquine (+)- and (-)-enantiomers and the carboxy metabolite in dried blood spots by LC MS/MS
Mirjam C.K. Geditz, Wolfgang Lindner, Michael Lämmerhofer, Georg Heinkele, Reinhold Kerb, Michael Ramharter, Matthias Schwab, Ute Hofmann
J. Chromatogr. B, 968 (2014) 32-39
2013
Direct high-performance liquid chromatographic enantioseparation of free α-, β- and γ-aminophosphonic acids employing cinchona-based chiral zwitterionic ion exchangers
Andrea F. G. Gargano, Michal Kohout, Pavla Macíková, Michael Lämmerhofer, Wolfgang Lindner
Anal. Bioanal. Chem., 405 (2013) 8027-8038
DOI: 10.1007/s00216-013-6938-6
Chemoaffinity material for plasmid DNA analysis by HPLC with condition-dependent switching between isoform and topoisomer selectivity
M. Mahut, A. Gargano, H. Schuchnigg, W. Lindner, M. Lämmerhofer
Anal. Chem., (2013) 2913-2920
Metabolomics in Practice, Successful Strategies to Generate and Analyze Metabolic Data
Lämmerhofer, Michael / Weckwerth, Wolfram (eds.)
1. Auflage Januar 2013
ISBN 978-3-527-33089-8 Wiley-VCH, Weinheim
Quantifying Thiol Ligand Density of Self-Assembled Monolayers on Gold Nanoparticles by Inductively Coupled Plasma Mass Spectrometry
H. Hinterwirth, S. Kappel, T. Waitz, T. Prohaska, W. Lindner and M. Lämmerhofer
ACS Nano, 7 (2013),1129-1136
Comparative method evaluation for size and size-distribution analysis of gold nanoparticles
H. Hinterwirth, S. K. Wiedmer, M. Moilanen, A. Lehner, G. Allmaier, T. Waitz, W. Lindner, M. Lämmerhofer
J. Sep. Sci., 36 (2013) 2952–2961
Phosphopeptidomimetic substance libraries from multicomponent reaction: Enantioseparation on quinidine carbamate stationary phase
A.F.G. Gargano, W.Lindner, M. Lämmerhofer
J. Chromatogr. A, 1310 (2013) 56– 65
DOI: 10.1016/j.chroma.2013.08.019
Mixed-mode chromatography with zwitterionic phosphopeptidomimetic selectors from Ugi multicomponent reaction
A.F.G. Gargano, T. Leek, W.Lindner, M. Lämmerhofer
J. Chromatogr. A, 1317 (2013) 12-21
DOI: 10.1016/j.chroma.2013.07.095
Gold nanoparticle-conjugated anti-oxidized low-density lipoprotein antibodies for targeted lipidomics of oxidative stress biomarkers
H. Hinterwirth, G. Stübiger, W. Lindner, M. Lämmerhofer
Anal. Chem., 85 (2013) 8376-8384
Single step Ugi Multicomponent Reaction for the synthesis of phosphopeptidomimetics
A.F.G. Gargano, S. Buchinger, M. Kohout, W. Lindner, M. Lämmerhofer
J. Org. Chem., 78 (2013) 10077–10087
Aminothiazole-featured pirinixic acid derivatives as dual 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 inhibitors with improved potency and efficiency in vivo.
T. Hanke, F. Dehm, S. Liening, S.D. Popella, J. Maczewsky, M. Pillong, J. Kunze, C. Weinigel, D. Barz, A. Kaiser, M. Wurglics, M. Lämmerhofer, G. Schneider, L. Sautebin, M. Schubert-Zsilavecz, O. Werz
J. Med. Chem., 56 (2013) 9031–9044
Special Issue: Trends 2013 (in honor of Prof. Frantisek Svec)
M. Lämmerhofer (Editor)
J. Sep. Sci., 36 (2013) 17
Trends in Separation Science (editorial)
M. Lämmerhofer
J. Sep. Sci., 36 (2013)
Virtual Special Issue: HILIC and Mixed-modes
M. Lämmerhofer (Editor)
J. Sep. Sci.
2012
Bioconjugation of trypsin onto gold nanoparticles: effect of surface chemistry on bioactivity
H. Hinterwirth, W. Lindner, M. Lämmerhofer
Anal. Chim. Acta, 733 (2012), 90-97
DOI: 10.1016/j.aca.2012.04.036
Trendbericht: Analytische Chemie 2010/2011
Boris Mizaikoff, Michael Lämmerhofer, José A.C. Broekaert, Jürgen Popp, Bernhard Lendl, Kerstin Leopold, Frieder W. Scheller, Aysu Yarman, Soeren Schumacher, Nicolas Plumeré, Andreas Hennig, Werner Nau, Christine Kranz, Jürgen W. Einax
Nachrichten aus der Chemie, 60 (4) (2012), 406–420
DOI: 10.1002/nadc.201290145
Activation of a silent phenazine biosynthetic gene cluster reveals a novel natural product and a new resistance mechanism against phenazines
Orwah Saleh, Tobias Bonitz, Katrin Flinspach, Andreas Kulik, Nadja Burkard, Agnes Mühlenweg, Andreas Vente, Stefan Polnick, Michael Lämmerhofer, Bertolt Gust, Hans-Peter Fiedler and Lutz Heide
MedChemComm., 3 (2012), 1009-1019
Quantitative LC-MS/MS impurity profiling methods for the analysis of parenteral infusion solutions for amino acid supplementation containing L-Alanyl-L-Glutamine
S. Schiesel, M. Lämmerhofer, A. Leitner, W. Lindner
J. Chromatogr. A, 1259 (2012), 111-120
DOI: 10.1016/j.chroma.2012.01.020
Comprehensive impurity profiling of multi-component nutritional infusion solutions for amino acid supplementation by a multidimensional analysis assay using off-line RPLC x HILIC – ion-trap MS and charged aerosol detection with universal calibration
S. Schiesel, M. Lämmerhofer, W. Lindner
J. Chromatogr. A, 1259 (2012), 100-110
DOI: 10.1016/j.chroma.2012.01.009
Analysis of Phytosiderophore-Metal Complexes in soil related samples: CE-MS vs. LC-MS
Madeleine Dell’mour, Walter Schenkeveld, Eva Oburger, Lisa Fischer, Stephan Kraemer, Markus Puschenreiter, Michael Lämmerhofer, Gunda Koellensperger, Stephan Hann
Electrophoresis, 33 (2012), 726–733
Molecular recognition principles and stationary phase characteristics of topoisomer-selective chemoaffinity materials for chromatographic separation of circular plasmid DNA topoisomers
Marek Mahut, Wolfgang Lindner, Michael Lämmerhofer
J. Am. Chem. Soc., 134 (2012), 859–862
Plasmid DNA manufacturing: Topology-selective chromatography reveals plasmid supercoiling shifts during fermentation and allows large-scale production of topoisomers
M. Mahut, E. Haller, P. Ghazidezfuli, M. Leitner, P. Hinterdorfer, W. Lindner, M. Lämmerhofer
Angew. Chem. Int. Ed., 51 (2012), 267-270
for the International Edition: DOI: 10.1002/anie.201106495
for the German Edition: DOI: 10.1002/ange.201106495
Time-resolved chloroquine-induced relaxation of supercoiled plasmid DNA bionanoparticles
Mahut, Marek; Leitner, Michael; Ebner, Andreas; Laemmerhofer, Michael; Hinterdorfer, Peter; Lindner, Wolfgang
Anal. Bioanal. Chem., 402 (2012), 373-380
DOI: 10.1007/s00216-011-5213-y
Optimization Strategies accounting for the Additive in Preparative Chiral Liquid Chromatography
Patrik Forssen, Lena Edström, Michael Lämmerhofer, Jörgen Samuelsson, Anders Karlsson, Wolfgang Lindner, Torgny Fornstedt
J. Chromatogr. A., 1269 (2012), 279– 286
DOI: 10.1016/j.chroma.2012.05.052
Enantioseparation of Chiral Sulfonic Acids by Liquid Chromatography and Subcritical Fluid Chromatography
Reinhard Pell, Georg Schuster, Michael Lämmerhofer, Wolfgang Lindner
J. Sep. Sci., 35 (2012), 2521 -2528
Enantiomer and topoisomer separation of acidic compounds on anion-exchanger chiral stationary phases by HPLC and SFC
Pilar Franco, Tong Zhang, Andrea Gargano, Marek Mahut, Michael Lämmerhofer and Wolfgang Lindner
LC-GC Europe, 25 (2012), 600-610
Special Issue: Separation Science in Biotechnology
M. Lämmerhofer (Editor)
J. Sep. Sci., Volume 35, Issue 22 (2012)
Separation Science: Enabling Technology in Biotech (Editorial)
M. Lämmerhofer
J. Sep. Sci., 35 (2012)
Special Issue: Chiral Separation and Enantioselectivity
M. Lämmerhofer (Editor)
J. Chromatogr. A, 1269 (2012)
Chiral Separations and Enantioselectivity (Editorial)
M. Lämmerhofer
J. Chromatogr. A, 1269 (2012), 1-2
2011
Comparison of microparticulate and monolithic columns for RP-LC of tryptic digests of industrial enzymes in cleaning products
M. Beneito-Cambra, J.M. Herrero-Martínez, G. Ramis-Ramos, W. Lindner, M. Lämmerhofer
J. Chromatogr. A, 1218 (2011), 7275-7280
DOI: 10.1016/j.chroma.2011.08.055
Multi-step surface functionalization of polyimide based evanescent wave photonic biosensors and application for DNA hybridization by Mach-Zehnder Interferometer
Eva Melnik, Roman Bruck, Rainer Hainberger, Michael Lämmerhofer
Anal. Chim. Acta, 699 (2011), 206– 215
DOI: 10.1016/j.aca.2011.05.017
Integrated polymer-based Mach-Zehnder interferometer label-free streptavidin biosensor compatible with injection molding
R. Bruck, E. Melnik, P. Muellner, R. Hainberger, M. Lämmerhofer
Biosens. Bioelectron., 26 (2011), 3832-3837
DOI: 10.1016/j.bios.2011.02.042
Multi-modal applicability of a reversed-phase/weak-anion exchange material in reversed-phase, anion-exchange, ion-exclusion, hydrophilic interaction and hydrophobic interaction chromatography modes
M. Lämmerhofer*, R. Nogueira, W. Lindner
Anal. Bioanal. Chem., 400 (2011), 2517–2530
DOI: 10.1007/s00216-011-4755-3
Simultaneous separation and analysis of water- and fat-soluble vitamins on multi-modal reversed phase – weak anion exchange material by HPLC-UV
R. Dabre, N. Azada, A. Schwämmle, M. Lämmerhofer, W. Lindner
J. Sep. Sci., 34 (2011), 761-772
DOI: 10.1002/jssc.201000793