Development and optimization of extraction and pre-concentration methods for glyphosate and its metabolites in Environmental samples

Contact: Zahra.shamsispam prevention@mnf.uni-tuebingen.de

19 October 2025

Environmental Background: 

Glyphosate is one of the most widely used herbicides worldwide, and its presence in water resources has become a major environmental concern. Due to its high polarity and strong interaction with metal ions and mineral surfaces, its extraction and determination of trace levels remain challenging. Reliable analytical methods are therefore essential for accurate monitoring of glyphosate and its main metabolite, AMPA, in environmental samples.

This master project focuses on developing and optimizing efficient sample preparation and enrichment methods prior to chromatographic analysis, improving sensitivity and selectivity for environmental applications.

Goals of the Project:

1- Development of extraction and preconcentration procedures for glyphosate and AMPA (e.g., SPE, magnetic or hybrid materials).
2- Optimization of derivatization and chromatographic separation conditions (HPLC-UV or IC-ECD).
3- Evaluation of matrix effects and method validation for real environmental samples.

We are looking for a motivated master student who:

Is interested in analytical chemistry, environmental monitoring, and chromatography.

Enjoys laboratory work and method development.

Has a background in chemistry, environmental science, or related fields.

Communicates well and is eager to learn in a collaborative environment

We offer:

A well-structured and supervised thesis project.

Training in modern extraction and chromatographic techniques.

Involvement in ongoing research on herbicide analysis and environmental remediation.

A supportive laboratory atmosphere and close scientific guidance.