Publications

cGMP modulates hemin-mediated platelet death

Anne-Katrin Rohlfing, Marcel Kremser, David Schaale, Valerie Dicenta-Baunach, Zoi Laspa, Xiaoqing Fu, Laimdota Zizmare, Manuel Sigle, Tobias Harm, Patrick Münzer, Andreas Pelzer, Oliver Borst, Christoph Trautwein, Robert Feil, Karin Müller, Tatsiana Castor, Michael Lämmerhofer, Meinrad P. Gawaz, Thrombosis Research, (2023);
https://doi.org/10.1016/j.thromres.2023.12.008

Commensal production of a broad spectrum and short-lived antimicrobial peptide polyene eliminates nasal Staphylococcus aureus

Benjamin O. Torres Salazar, Taulant Dema, Nadine A. Schilling, Daniela Janek, Jan Bornikoel, Anne Berscheid, Ahmed M. A. Elsherbini, Sophia Krauss, Simon J. Jaag, Michael Lämmerhofer, Min Li, Norah Alqahtani, Malcolm J. Horsburgh, Tilmann Weber, José Manuel Beltrán-Beleña, Heike Brötz-Oesterhelt, Stephanie Grond, Bernhard Krismer, Andreas Peschel, Nature Microbiology, (2023)

https://doi.org/10.1038/s41564-023-01544-2

mitoBKCa is functionally expressed in murine and human breast cancer cells and promotes metabolic reprogramming

Helmut Bischof, Selina Maier, Piotr Koprowski, Bogusz Kulawiak, Sandra Burgstaller, Joanna Jasińska, Kristian Serafimov, Dominic Gross, Werner Schroth, Lucas Matt, David Arturo Juarez Lopez, Irina Bonzheim, Florian A. Büttner, Falko Fend, Matthias Schwab, Andreas L. Birkenfeld, Roland Malli, Michael Lämmerhofer, Piotr Bednarczyk, Adam Szewczyk, Robert Lukowski, eLife 12 (2023) RP92511

https://doi.org/10.7554/eLife.92511.1

Quantitative analysis of the glutathione pathway cellular metabolites by targeted liquid chromatography-tandem mass spectrometry

Kristian Serafimov, Yüsra Aydin, Michael Lämmerhofer, J. Sep. Sci., (2023)

https://doi.org/10.1002/jssc.202300780

Crosslinked polysiloxane-coated stable bond O-9-(2,6-diisopropylphenylcarbamoyl)quinine and quinidine chiral stationary phases as well as application in enantioselective cryo-HPLC

Ulrich Woiwode, Adrian Sievers-Engler, Michael Lämmerhofer, Electrophoresis, (2023)

https:///doi.org/10.1002/elps.202300182

Large‑scale lipidomics profiling reveals characteristic lipid signatures associated with an increased cardiovascular risk

Tobias Harm, Kristina Dittrich, Adrian Brun, Xiaoqing Fu, Moritz Frey, Alvaro Petersen Uribe, Frederic‑ Joaquim Schwarz, Anne‑ Katrin Rohlfing, Tatsiana Castor, Tobias Geisler, Dominik Rath, Michael Lämmerhofer, Meinrad P. Gawaz, Clin. Res. Cardiol., (2023)

https://doi.org/10.1007/s00392-023-02260-x

Automated Sample Preparation with 6-Aminoquinolyl-N -hydroxysccinimidyl Carbamate and Iodoacetamide Derivatization Reagents for Enantioselective Liquid Chromatography Tandem Mass Spectrometry Amino Acid Analysis

Feiyang Li, Ryan Karongo, Despoina Mavridou, Jeannie Horak, Adrian Sievers-Engler, Michael Lämmerhofer, J. Chromatogr. A, 1708 (2023) 464349

https://doi.org/10.1016/j.chroma.2023.464349

Principles and Applications of CF2X Moieties as Unconventional Halogen Bond Donors in Medicinal Chemistry, Chemical Biology, and Drug Discovery

Sebastian Vaas, Markus O. Zimmermann, Dieter Schollmeyer, Jason Stahlecker, Marc U. Engelhardt, Janosch Rheinganz, Bernhard Drotleff, Matthias Olfert, Michael Lämmerhofer, Markus Kramer, Thilo Stehle, and Frank M. Boeckler

https://doi.org/10.1021/acs.jmedchem.3c00634

Ion-pair-free RPLC-MS of synthetic oligonucleotides Impurity analysis of siRNA with a polybutylene terephthalate-based column

Feiyang Li, Shenkai Chen, Sylwia Studzińska, Michael Lämmerhofer, chrom+food forum 06 (2023) 4-6.

Evaluation of Kinetic Performance of Reversed-Phase Columns for Protein Separations by Gradient Kinetic Plots

Simon Jaag, Michael Lämmerhofer, LCGC Supplement, May 2 (2023)

https://doi.org/10.56530/lcgc.eu.bm1469g6

Comprehensive reversed-phase×chiral two-dimensional liquid chromatography coupled to quadrupole-time-of-flight tandem mass spectrometry with post-first dimension flow splitting for untargeted enantioselective amino acid analysis

Ryan Karongo, Jeannie Horak, Michael Lämmerhofer, J. Sep.Sci., (2023)

http://doi.wiley.com/10.1002/jssc.202300351

Profiling of branched chain and straight chain saturated fatty acids by ultra-high performance liquid chromatography-mass spectrometry

Xiaoqing Fu, Nourhane Hafza, Friedrich Götz, Michael Lämmerhofer, J. Chromatogr. A, (2023) 464111

https://doi.org/10.1016/j.chroma.2023.464111

Chiral stationary phases derived from cinchona alkaloids

Michael Lämmerhofer, Wolfgang Lindner, in: Quezia B Cass, Maria Elizabeth Tiritan, Juliana Cristina Barreiro and João Marco Batista Junior (eds.), Chiral Separations and Stereochemical Elucidation: Fundamentals, Methods, and Applications, Chapter 11, Wiley, 2023, p. 415-472, ISBN: 978-1-119-80225-9.

The Subtilisin-Like Protease Furin Regulates Hemin-Dependent Ectodomain Shedding of Glycoprotein VI.

Fink A, Rohlfing AK, Dicenta V, Schaale D, Kremser M, Laspa Z, Sigle M, Fu X, Pelzer A, Fischer M, Münzer P, Castor T, Müller KAL, Borst O, Lämmerhofer M, Gawaz MP. Thromb. Haemost., (2023)

https://doi.org/10.1055/s-0043-1768057

Polybutylene terephthalate-based stationary phase for for ion-pair-free reversed-phase liquid chromatography of small interfering RNA. Part 2: Use for selective comprehensive two-dimensional liquid chromatography

Feiyang Li, Shenkai Chen, Sylwia Studzińska, Michael Lämmerhofer, J. Chromatogr. A, (2023) 464069,

https://doi.org/10.1016/j.chroma.2023.464069

Ionenpaar-freie RPLC-MS von Oligonukleotiden: Anwendung für die Verunreinigungsanalytik von siRNA mithilfe einer Polybutylenterephthalat-basierten Säule

Feiyang Li, Shenkai Chen, Sylwia Studzińska, Michael Lämmerhofer, chrom+food forum 04 (2023) 44-46.

Basic principles for the selection of liquid chromatographic modes for specific applications.

Carlos Calderón, Michael Lämmerhofer, in: Salvatore Fanali, Bezhan Chankvetadze, Paul R. Haddad, Colin F. Poole and Marja-Liisa Riekkola (Eds.) Handbooks in Separation Science. Liquid Chromatography Volume 2 Applications, 3^rd edition, Elsevier, Amsterdam, Netherlands, ISBN: 978-0-323-99969-4

https://doi.org/10.​1016/​B978-0-323-99969-4.​00101-7

Nutritional lipidomics for the characterization of lipids in food

Carlos Calderón, Michael Lämmerhofer, Advances in Food and Nutrition Research (Book series), 2023, Elsevier, Amsterdam.

https://doi.org/10.1016/bs.afnr.2022.12.002

Statin Treatment Is Associated with Alterations in the Platelet Lipidome

Tobias Harm, Moritz Frey, Kristina Dittrich, Andreas Goldschmied, Anne-Katrin Rohlfing,
Xiaoqing Fu, Adrian Brun, Tatsiana Castor, Dominik Rath, Karin Müller, Michael Lämmerhofer, Meinrad Gawaz, Thrombosis und Haemostasis, (2023),

https://doi.org/10.1055/s-0043-1764353

Polybutylene terephthalate-based stationary phase for for ion-pair-free reversed-phase liquid chromatography of small interfering RNA. Part 1: Direct coupling with mass spectrometry

Feiyang Li, Shenkai Chen, Sylwia Studzińska, Michael Laemmerhofer, J. Chromatogr. A, (2023) 463898,

https://doi.org/10.1016/j.chroma.2023.463898

Application of Two-Dimensional Liquid Chromatography to the Analysis of Chiral and Structurally Similar Molecules
Michael Lämmerhofer, Carlos Calderón, in: Dwight R. Stoll and Peter W. Carr (Eds.), Multi-Dimensional Liquid Chromatography: Principles, Practice, and Applications, CRC Press, Boca Raton, FL, USA (Taylor and Francis Group, London), 2023. ISBN 9780367547660, 1st Edition,

https://doi.org/10.1201/9781003090557

Isomer selectivity of mixed-mode and hydrophilic interaction liquid chromatography coupled to tandem mass spectrometry for sugar phosphates of glycolysis and pentose phosphate pathways

Min Su, Kristian Serafimov, Peng Li, Cornelius Knappe, Michael Lämmerhofer, J. Chromatogr. A, (2022) 463727;

https://doi.org/10.1016/j.chroma.2022.463727

Application of cholesterol stationary phase for the separation and identification of siRNA impurities by two-dimensional liquid chromatography-mass spectrometry

Sylwia Studzińska, Feiyang Li, Michał Szumski, Bogusław Buszewski, Michael Lämmerhofer, Int. J. Mol. Sci., 23 (2022), 14960;

https://doi.org/10.3390/ijms232314960

UHPLC-MS/MS method for chiral separation of 3-hydroxy fatty acids on amylose-based chiral stationary phase and its application for the enantioselective analysis in plasma and platelets

Xiaoqing Fu, Zhanjian Xu, Meinrad Gawaz, Michael Lämmerhofer, J. Pharm. Biomed. Anal., (2022) 115151

https://doi.org/10.1016/j.jpba.2022.115151

Branched medium-chain fatty acid profiling and enantiomer separation of anteiso-forms of teicoplanin fatty acyl side chain RS3 using UHPLC-MS/MS with polysaccharide columns

Christian Geibel, Matthias Olfert, Cornelius Knappe, Kristian Serafimov, Michael Lämmerhofer, J. Pharm. Biomed. Anal., (2022)

https://doi.org/10.1016/j.jpba.2022.115162

Comprehensive Online Reversed-phase×Chiral Two-dimensional Liquid Chromatography-Mass Spectrometry with Data-independent SWATH-Acquisition for Untargeted Enantioselective Amino Acid Analysis

Ryan Karongo, Jeannie Horak, Michael Lämmerhofer, Anal. Chem., (2022)

https://doi.org/10.1021/acs.analchem.2c03042.
 

Revisiting a challenging p53 binding site: a diversity-optimized HEFLib reveals diverse binding modes in T-p53C-Y220C

Jason Stahlecker, Theresa Klett, Martin Schwer, Simon Jaag, Marcel Dammann, Larissa N. Ernst, Michael Braun, Markus O. Zimmermann, Markus Kramer, Michael Lämmerhofer, Thilo Stehle, Murray Colese, Frank M. Boeckler, RSC Med. Chem., (2022)

https://doi.org/10.1039/D2MD00246A.

Generation of 13C-labeled inositol and inositol phosphates by stable isotope labeling cell culture for quantitative metabolomics

Peng Li, Michael Lämmerhofer, Anal. Chem., (2022)

https://doi.org/10.1021/acs.analchem.2c02819

Retentionskinetiken unter der Lupe: Ein genauer Blick auf die Kinetiken in vollporösen (FPP) und oberflächenporösen Partikeln (SPP) mit chiralen ZWIX-Selektoren

Christian Geibel, Kristina Dittrich, Ulrich Woiwode, Michal Kohout, Tong Zhang, Wolfgang Lindner, Michael Lämmerhofer, chrom+food forum, 06 (2022) 6-8

UHPLC-ESI-MS/MS assay for quantification of endocannabinoids in cerebrospinal fluid using surrogate calibrant and surrogate matrix approaches

Ece Aydin, Malgorzata Cebo, Justyna Mielnik, Hardy Richter, Rebecca Schüle, Adrian Sievers-Engler, Piotr Młynarz, Michael Lämmerhofer, J. Pharm. Biomed. Anal., 222 (2023) 115090

https://doi.org/10.1016/j.jpba.2022.115090

Lower affective empathy in oral contraceptive users: a cross-sectional fMRI study

Kimmig A-C.S., Wildgruber D., Gärtner A., Drotleff B., Krylova M., Lämmerhofer M., Sundström-Poromaa I., Derntl B., Cerebral Cortex, bhac345,

https://doi.org/10.1093/cercor/bhac345

Metabolic profiling workflow for urine, plasma and cell extracts by targeted hydrophilic interaction liquid chromatography-tandem mass spectrometry

Kristian Serafimov, Michael Lämmerhofer, J. Chromatogr. A, 1684 (2022) 463556

https://doi.org/10.1016/j.chroma.2022.463556

Starting or Discontinuing the Pill – changes in progestogens reflected by resting-state connectivity and positive mood

Kimmig A-C.S, Friedrich P. Drotleff B. Lämmerhofer M. Sundström-Poromaa I., Weis S., Derntl B., BioRxiv, 2022

https://doi.org/10.1101/2022.09.21.508780

Quality-by-Design Approach for Development of Aqueous Headspace Microextraction GC-MS Method for Targeted Metabolomics of Small Aldehydes in Plasma of Cardiovascular Patients

Rasha S. Hanafi, Michael Lämmerhofer, Anal. Chim. Acta, (2022) 340176

https://doi.org/10.1016/j.aca.2022.340176

Targeted analysis of sugar phosphates from glycolysis pathway by phosphate methylation with liquid chromatography coupled to tandem mass spectrometry

Peng Li, Min Su, Madhumita Chatterjee, Michael Lämmerhofer, Anal. Chim. Acta, 1221 (2022) 340099

https://doi.org/10.1016/j.aca.2022.340099

Advanced unified monophasic lipid extraction protocol with wide coverage on the polarity scale optimized for large-scale untargeted clinical lipidomics analysis of platelets

Xiaoqing Fu, Carlos Calderón, Tobias Harm, Meinrad Gawaz, Michael Lämmerhofer, Anal. Chim. Acta, (2022), 340155

https://doi.org/10.1016/j.aca.2022.340155

Kinetic performance comparison of superficially porous, fully porous and monolithic reversed-phase columns by gradient kinetic plots for the separation of protein biopharmaceuticals

Simon Jaag, Chunmei Wen, Benjamin Peters, Michael Lämmerhofer, J. Chromatogr. A, 1676 (2022), 463251

https://doi.org/10.1016/j.chroma.2022.463251

Aß1-42 peptide toxicity on neuronal cells: a lipidomic study

Lara Davani, Xiaoqing Fu, Angela De Simone, Peng Li, Serena Montanari, Michael Lämmerhofer, and Vincenza Andrisano, J. Pharm. Biomed. Anal., (2022) 114876

https://doi.org/10.1016/j.jpba.2022.114876

Study of microheterogeneity of silatrane-based silica surface bonding chemistry and its optimization for the synthesis of chiral stationary phases for enantioselective liquid chromatography

Christian Geibel, Markus Kramer, Michael Lämmerhofer, J. Chromatogr. A, (2022) 463138

https://doi.org/10.1016/j.chroma.2022.463138

Development and chromatographic exploration of stable-bonded crosslinked amino silica against classical amino phases

Marc Wolter, Christian Geibel, Matthias Olfert, Min Su, Wolfgang Bicker, Wolfgang Lindner, Markus Kramer, Michael Lämmerhofer, J. Sep. Sci., (2022).

https://doi.org/10.1002/jssc.202200268

ACKR3 regulates platelet activation and ischemia-reperfusion tissue injury

Anne-Katrin Rohlfing, Kyra Kolb, Manuel Sigle, Melanie Ziegler, Alexander Bild, Patrick Münzer, Jessica Sudmann, Valerie Dicenta, Tobias Harm, Mailin-Christin Manke, Sascha Geue, Marcel Kremser, Madhumita Chatterjee, Chunguang Liang, Hendrik von Eysmondt, Thomas Dandekar, David Heinzmann, Manina Günter, Saskia von Ungern-Sternberg, Manuela Büttcher, Tatsiana Castor, Stine Mencl, Friederike Langhauser, Katharina Sies, Diyaa Ashour, Mustafa Caglar Beker, Michael Lammerhofer, Stella E. Autenrieth, Tilman E. Schaffer, Stefan Laufer, Paulina Szklanna, Patricia Maguire, Matthias Heikenwalder, Karin Anne Lydia Müller, Dirk M. Hermann, Ertugrul Kilic, Ralf Stumm, Gustavo Ramos, Christoph Kleinschnitz, Oliver Borst, Harald F Langer, Dominik Rath, Meinrad Gawaz, Nat Commun 13, 1823 (2022).

https://doi.org/10.1038/s41467-022-29341-1
 

Comprehensive profiling of conjugated fatty acid isomers and their lipid oxidation products by two-dimensional chiral RP×RP liquid chromatography hyphenated to UV- and SWATH-MS-detection

Matthias Olfert, Stefanie Bäurer, Marc Wolter, Stephan Buckenmaier, Edmundo Brito-de la Fuente, Michael Laemmerhofer, Anal. Chim. Acta, 1202 (2022) 339667,

https://doi.org/10.1016/j.aca.2022.339667

The molecular basis of rhodomyrtone resistance in Staphylococcus aureus

Li Huang, Carlos Calderón, Sook-Ha Fan, Aparna Ammanath, Xiaoqing Fu, Arif Luqman, Marvin Ullrich, Martin Maier, Anchun Cheng, Michael Lämmerhofer, and Friedrich Götz, mBio, 13 (2022) e03833-21,

https://doi.org/10.1128/mbio.03833-21

High Plasticity of the Amicetin Biosynthetic Pathway in Streptomyces sp. SHP 22-7 Led to the Discovery of Streptcytosine P and Cytosaminomycins F and G and Facilitated the Production of 12F-Plicacetin

Niraj Aryal, Junhong Chen, Oliver Hennrich, Ira Handayani, Markus Kramer, Jan Straetener, Heike Brötz-Oesterhelt, Christian Geibel, Michael Lämmerhofer, Yvonne Mast, Harald Gross, J. Nat. Prod., (2022)

https://doi.org/10.1021/acs.jnatprod.1c01051

Sex-dependent multimodal response profiles to psychosocial stress

Leandra Kuhn, Hannes Noack, Lisa Wagels, Anna Prothmann, Anna Schulik, Ece Aydin, Vanessa Nieratschker, Birgit Derntl, Ute Habel; Cerebral Cortex (2022)

https://doi.org/10.1093/cercor/bhac086

No Evidence for a Role of Oral Contraceptive-Use in Emotion Recognition But Higher Negativity Bias in Early Follicular Women

Kimmig, Ann-Christin Sophie; Bischofberger, Jasper Amadeus; Birrenbach, Annika Dorothea; Drotleff, Bernhard; Lämmerhofer, Michael; Sundström-Poromaa, Inger; Derntl, Birgit, Frontiers in Behavioral Neuroscience, (2022)

https://doi.org/10.3389/fnbeh.2021.773961

Towards enantioselective ultra-high performance liquid chromatography-mass spectrometry-based metabolomics of branched short-chain fatty acids and anteiso-fatty acids under reversed phase conditions using sub-2µm amylose- and cellulose-derived chiral stationary phases

Christian Geibel, Li Zhang, Kristian Serafimov, Harald Gross, Michael Lämmerhofer, Chirality, 34 (2022), 484-497

https://doi.org/10.1002/chir.23413.

Isomer-selective analysis of inositol phosphates with differential isotope labelling by phosphate methylation using liquid chromatography with tandem mass spectrometry

Peng Li, Meinrad Gawaz, Madhumita Chatterjee, Michael Lämmerhofer, Anal. Chim. Acta, 1191 (2022) 339286

https://doi.org/10.1016/j.aca.2021.339286

Enantioselective metabolomics by liquid chromatography-mass spectrometry

Carlos Calderón, Michael Lämmerhofer, J. Pharm. Biomed. Anal., 207 (2022), 114430

https://doi.org/10.1016/j.jpba.2021.114430

Distinct and convergent beneficial effects of estrogen and insulin on cognitive function in healthy young men

Rosemarie Krug, Laura Beier, Michael Lämmerhofer, Manfred Hallschmid, J. Clin. Endocrinol. Metab., 107 (2022), e582-e593

https://doi.org/10.1210/clinem/dgab689

Platelet ACKR3/CXCR7 Favors Anti-Platelet Lipids over an Atherothrombotic Lipidome and Regulates Thrombo-inflammation

Malgorzata Cebo, Kristina Dittrich, Xiaoqing Fu, Mailin-Christin Manke,  Frederic Emschermann, Johannes Rheinlaender, Hendrik Von Eysmondt, Nerea Ferreirós, Jessica Sudmann-Innerhofer, Alexander Witte, Lisann Pelzl, Oliver Borst, Tobias Geisler, Dominik Rath, Tamam Bakchoul, Meinrad Gawaz, Tilman E. Schäffer, Michael Lämmerhofer, and Madhumita Chatterjee, Blood, (2022)

https://doi.org/10.1182/blood.2021013097

Enantioselective UHPLC Screening Combined with In Silico Modeling for Streamlined Development of Ultrafast Enantiopurity Assays

Gioacchino Luca Losacco, Heather Wang, Imad A. Haidar Ahmad, Jimmy DaSilva, Alexey A. Makarov, Ian Mangion, Francesco Gasparrini, Michael Lämmerhofer, Daniel W. Armstrong, Erik L. Regalado, Anal. Chem., 94 (2022), 1804-1812

https://doi.org/10.1021/acs.analchem.1c04585

Acute coronary syndrome is associated with a substantial change in the platelet lipidome

Tobias Harm, Andreas Goldschmied, Kristina Dittrich, Madhumita Chatterjee, Kyra Kolb, Tatsiana Castor, Dominik Rath, Michael Lämmerhofer, Meinrad Gawaz, Cardiovasc. Res., (2022).

https://doi.org/10.1093/cvr/cvab238

Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent 9H-pyrimido[4,5-b]indole-based GSK-3β inhibitors

Andreev, Stanislav; Pantsar, Tatu; Tesch, Roberta; Kahlke, Niclas; El-Gokha, Ahmed; Ansideri, Francesco; Grätz, Lukas; Romasco, Jenny; Sita, Giulia; Geibel, Christian; Lämmerhofer, Michael; Tarozzi, Andrea; Knapp, Stefan; Laufer, Stefan; Koch, Pierre, J Med. Chem., 65 (2022), 1283-1301

https://doi.org/10.1021/acs.jmedchem.0c02146.

DoE Optimization Empowers the Automated Preparation of Enantiomerically Pure [18F]Talazoparib and its In Vivo Evaluation as a PARP Radiotracer
Gregory D. Bowden, Sophie Stotz, Johannes Kinzler, Christian Geibel, Michael Lämmerhofer, Bernd J. Pichler, and Andreas Maurer, J. Med. Chem., 64 (2021), 15690-15701

https://doi.org/10.1021/acs.jmedchem.1c00903

Fast accurate quantification of salivary cortisol and cortisone in a large-scale clinical stress study by micro-UHPLC-ESI-MS/MS using a surrogate calibrant approach

Ece Aydin, Bernhard Drotleff, Hannes Noack, Birgit Derntl, Michael Lämmerhofer, J. Chromatogr. B, 1182 (2021), 122939.

https://doi.org/10.1016/j.jchromb.2021.122939

Rapid enantioselective amino acid analysis by ultra-high performance liquid chromatography-mass spectrometry combining 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate derivatization with core-shell quinine carbamate anion exchanger separation

Ryan Karongo, Min Ge, Jeannie Horak, Harald Gross, Michal Kohout, Wolfgang Lindner, Michael Lämmerhofer, J. Chromatogr. Open, 1 (2021) 100004.

https://doi.org/10.1016/j.jcoa.2021.100004

Untargeted UHPLC-ESI-QTOF-MS/MS analysis with targeted feature extraction at precursor and fragment level for profiling of the platelet lipidome with ex vivo thrombin-activation

Malgorzata Cebo, Carlos Calderón Castro, Jörg Schlotterbeck, Meinrad Gawaz, Madhumita Chatterjee, Michael Lämmerhofer, J. Pharm. Biomed. Anal., 205 (2021) 114301.

https://doi.org/10.1016/j.jpba.2021.114301

Enantioselective multiple heart cutting online two-dimensional liquid chromatography-mass spectrometry of all proteinogenic amino acids with second dimension chiral separations in one-minute time scales on a chiral tandem column

Ryan Karongo, Min Ge, Christian Geibel, Jeannie Horak, Michael Laemmerhofer, Anal. Chim. Acta, 1180 (2021) 338858.

https://doi.org/10.1016/j.aca.2021.338858

Controllable organosilane monolayer density of surface bonding using silatranes for thiol functionalization of silica particles for liquid chromatography and validation of microanalytical method for elemental composition determination

Christian Geibel, Johannes Theiner, Marc Wolter, Markus Kramer, Wolfgang Lindner, Michael Lämmerhofer, J. Chromatogr. A, 1653 (2021) 462418.

https://doi.org/10.1016/j.chroma.2021.462418

LC-MS Lipidomik unter Verwendung von SWATH: Globale daten-unabhängige Erzeugung von Massenspektren

Kristina Dittrich, Bernhard Drotleff, Carlos Calderón Castro, Malgorzata Cebo, Xiaoqing Fu, Michael Lämmerhofer

Wiley Analytical Science, June 22 (2021).

https://analyticalscience.wiley.com/do/10.1002/was.000600131

Isomer selective comprehensive lipidomics analysis of phosphoinositides in biological samples by liquid chromatography with data independent acquisition tandem mass spectrometry

Peng Li, Michael Lämmerhofer, Anal. Chem., 93 (2021) 9583–9592.

https://doi.org/10.1021/acs.analchem.1c01751

Chiral metabolomics

C. Calderon, M. Lämmerhofer, in: Rawi Ramautar (Ed.) Advanced Mass Spectrometry-based Analytical Separation Techniques for Probing the Polar Metabolome

Royal Society of Chemistry, London, 2021.

https://doi.org/10.1039/9781839163524

Impurity profiling of siRNA by two-dimensional liquid chromatography-mass spectrometry with quininecarbamate anion-exchanger and ion-pair reversed-phase chromatography

Feiyang Li, Michael Lämmerhofer, J. Chromatogr. A, 1643 (2021) 462065.

https://doi.org/10.1016/j.chroma.2021.462065

Preparation and characterization of poly(3-mercaptopropyl)methylsiloxane functionalized silica particles and their further modification for silver ion chromatography and enantioselective high-performance liquid chromatography

Marc Wolter, Xingyue Chen, Ulrich Woiwode, Christian Geibel, Michael Lämmerhofer, J. Chromatogr. A, 1643 (2021) 462069.

https://doi.org/10.1016/j.chroma.2021.462069

Direct enantioselective gradient reversed-phase ultra-high performance liquid chromatography - tandem mass spectrometry method for 3-hydroxy alkanoic acids in lipopeptides on immobilized 1.6 µm amylose-based chiral stationary phase

Ryan Karongo, Junjing Jiao, Harald Gross, Michael Lämmerhofer, J. Sep. Sci., 44 (2021), 1875-1883

https://doi.org/10.1002/jssc.202100104

Targeted profiling of short-, medium- and long-chain fatty acyl-Coenzyme As in biological samples by phosphate methylation coupled to liquid chromatography–tandem mass spectrometry

Peng Li, Meinrad Gawaz, Madhumita Chatterjee, Michael Lämmerhofer, Anal. Chem., 93 (2021) 4342-4350.

https://doi.org/10.1021/acs.analchem.1c00664

Untargeted LC–MS Lipidomics with Data Independent Acquisition using Sequential Window Acquisition of All Theoretical Fragment-Ion Spectra

Bernhard Drotleff , Carlos Calderón Castro , Malgorzata Cebo , Kristina Dittrich , Xiaoqing Fu , Michael Lämmerhofer, LCGC Europe, 34 (1) (2021) 7–17.

Discovery of Thanafactin A, a New Linear Proline-containing Octa-Lipopeptide from Pseudomonas sp. SH-C52, motivated by genome mining

Norbert Kirchner, Carolina Cano-Prieto, Anna Schulz-Fincke, Michael Gütschow, Nico Ortlieb, Julia Moschny, Timo Niedermeyer, Jeannie Horak, Michael Lämmerhofer, Menno  Van der Voort, Jos Raaijmakers, Harald Gross, J. Nat. Prod., 84 (2021), 1, 101–109. 

https://doi.org/10.1021/acs.jnatprod.0c01174

Charge variant analysis of protein-based biopharmaceuticals using two-dimensional liquid chromatography hyphenated to mass spectrometry

Simon Jaag, Marina Shirokikh, Michael Lämmerhofer, J. Chromatogr. A, 1636 (2021) 461786.

https://doi.org/10.1016/j.chroma.2020.461786

Discovery and Evaluation of Enantiopure 9H-pyrimido[4,5-b]indoles as Nanomolar GSK-3β Inhibitors with Improved Metabolic Stability

Stanislav Andreev, Tatu Pantsar, Ahmed El-Gokha, Francesco Ansideri, Mark Kudolo, Débora Bublitz Anton, Giulia Sita, Jenny Romasco, Christian Geibel, Michael Lämmerhofer, Márcia Ines Goettert, Andrea Tarozzi, Stefan A. Laufer, Pierre Koch, Int. J. Mol. Sci., 21 (2020), 7823.

https://doi.org/10.3390/ijms21217823

Platelet Lipidomics: A Novel Approach to Assessing Cardiovascular Risk

Madhumita Chatterjee, Michael Lämmerhofer, Tilman Schäffer, Scientia Global, Mar 13, 2020

A Selective Comprehensive Reversed-phase×Reversed-phase 2D-Liquid Chromatography Approach with Multiple Complementary Detectors as Advanced Generic Method for the Quality Control of Synthetic and Therapeutic Peptides

Ryan Karongo, Tohru Ikegami, Dwight R Stoll, Michael Laemmerhofer, J. Chromatogr. A, 1627 (2020) 461430.

https://doi.org/10.1016/j.chroma.2020.461430

Breaking Boundaries with Bioanalysis

Sitting Down With… Michael Lämmerhofer, Professor of Pharmaceutical (Bio-)Analysis, Institute of Pharmaceutical Sciences, University of Tübingen, Germany

Interview in: The Analytical Scientist, 8, 2020; https://theanalyticalscientist.com/fields-applications/breaking-barriers-with-bioanalysis

Micro-UHPLC-MS/MS method for analysis of oxylipins in plasma and platelets

Malgorzata Cebo, Xiaoqing Fu, Meinrad Gawaz, Madhumita Chatterjee, Michael Lämmerhofer

J. Pharm. Biomed. Anal., (2020), 113426

https://doi.org/10.1016/j.jpba.2020.113426

Multiple Heart-Cutting Mixed-mode Chromatography-Reversed-phase 2D-Liquid Chromatography Method for Separation and Mass Spectrometric Characterization of Synthetic Oligonucleotides

Feiyang Li, Xiaoli Su, Stefanie Bäurer, Michael Laemmerhofer,

J. Chromatogr. A, (2020) 461338

https://doi.org/10.1016/j.chroma.2020.461338

Lipid atlas of keratinocytes and betulin effects on its lipidome profiled by comprehensive UHPLC-MS/MS with data independent acquisition using targeted data processing

Carlos Calderón, Lara Rubarth, Malgorzata Cebo, Irmgard Merfort, Michael Lämmerhofer

Proteomics, 20 (2020) 1900113.

https://doi.org/10.1002/pmic.201900113

Lipidomic profiling of non-mineralized dental plaque and biofilm by untargeted UHPLC-QTOF-MS/MS and SWATH acquisition

Bernhard Drotleff,  Simon Roth, Kerstin Henkel, Jörg Schlotterbeck, Merja Neukamm, Michael Laemmerhofer

Analytical and Bioanalytical Chemistry, 412 (2020) 2303–2314.

https://doi.org/10.1007/s00216-019-02364-2

Fragment-based Design of Zwitterionic, Strong Cation- and Weak Anion-Exchange Type Mixed-mode Liquid Chromatography Ligands and their Chromatographic Exploration

Martina Ferri, Stefanie Bäurer, Andrea Carotti, Marc Wolter, Belal Alshaar, Johannes Theiner, Tohru Ikegami, Caroline West, Michael Lämmerhofer

J. Chromatogr. A, 1621 (2020), 461075.

https://doi.org/10.1016/j.chroma.2020.461075

Thiol-ene photo-click immobilization of a chiral chromatographic ligand on silica particles

Christian Geibel, Kristina Dittrich, Marc Wolter, Michael Lämmerhofer

J. Chromatogr. A, 1622 (2020) 461133

 https://doi.org/10.1016/j.chroma.2020.461133

Enantioselective UHPLC-MS/MS method based on sub-2µm particle polysaccharide column for chiral separation of oxylipins and its application for the analysis of auto-oxidized fatty acids and platelet releasates

Malgorzata Cebo, Xiaoqing Fu, Meinrad Gawaz, Madhumita Chatterjee, Michael Lämmerhofer

J. Chromatogr. A, 1624 (2020) 461206

https://doi.org/10.1016/j.chroma.2020.461206

Separation of Carbohydrate Isomers and Anomers on Poly-N-(1H-tetrazole-5-yl)-methacrylamide-bonded Stationary Phase by Hydrophilic Interaction Chromatography as well as Determination of Anomer Interconversion Energy Barriers

Xiaoqing Fu, Malgorzata Cebo, Tohru Ikegami, Michael Lämmerhofer

J. Chromatogr. A, 1620 (2020), 460981

https://doi.org/10.1016/j.chroma.2020.460981

Cinchona-based zwitterionic stationary phases: Exploring retention and enantioseparation mechanisms in supercritical fluid chromatography with a fragmentation approach

Adrien Raimbault, Cam Mai Anh Ma, Martina Ferri, Stefanie Bäurer, Pascal Bonnet, Stéphane Bourg, Michael Lämmerhofer, Caroline West

J. Chromatogr. A, 1612 (2020), 460689.

https://doi.org/10.1016/j.chroma.2019.460689

Simultaneous targeted and untargeted UHPLC-ESI-MS/MS method with data-independent acquisition for quantification and profiling of (oxidized) fatty acids released upon platelet activation by thrombin

Malgorzata Cebo, Jörg Schlotterbeck, Meinrad Gawaz, Madhumita Chatterjee, Michael Lämmerhofer

Anal. Chim. Acta, 1094 (2020) 57-69.

https://doi.org/10.1016/j.aca.2019.10.005

Mixed-mode Chromatography Characteristics of Chiralpak ZWIX(+) and ZWIX(-) and Elucidation of their Chromatographic Orthogonality for LC×LC Application

Stefanie Bäurer, Martina Ferri, Andrea Carotti, Stefan Neubauer, Roccaldo Sardella, Michael Lämmerhofer

Anal. Chim. Acta, 1093 (2020) 168-179.

https://doi.org/10.1016/j.aca.2019.09.068

Retention Characteristics of Poly(N-(1H-tetrazole-5-yl)-methacrylamide)-bonded Stationary Phase in Hydrophilic Interaction Chromatography

Xiaoqing Fu, Malgorzata Cebo, Tohru Ikegami, Michael Lämmerhofer

J. Chromatogr. A, 1609 (2020), 460500.

https://doi.org/10.1016/j.chroma.2019.460500

In-situ photopolymerized polyhedral oligomeric silsesquioxane-derived monolithic capillary columns with quinidine functionality for enantioseparation by nano-liquid chromatography

Siyao Liu, Xinyue Fu, Ronny Löffler, Michael Lämmerhofer

Electrophoresis, 40 (2019), 3132-3139.

https://doi.org/10.1002/elps.201900316

Racemization without deamidation: Effect of racemization conditions on 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate tagged amino acids

Jeannie Horak, Michael Lämmerhofer.

 J. Chromatogr. A, 1604 (2019), 460492.

https://doi.org/10.1016/j.chroma.2019.460492

Comprehensive Lipidomics of Mouse Plasma using Class-Specific Surrogate Calibrants and SWATH Acquisition for Large-Scale Lipid Quantification in Untargeted Analysis

Bernhard Drotleff, Julia Illison, Jörg Schlotterbeck, Robert Lukowski, Michael Lämmerhofer

Anal. Chim. Acta, 1086 (2019), 90-102.

https://doi.org/10.1016/j.aca.2019.08.030

Guidelines for Selection of Internal Standard-based Normalization Strategies in Untargeted Lipidomic Profiling by LC-HR-MS/MS

Bernhard Drotleff, Michael Lämmerhofer

Anal. Chem., 2019, 91, 15, 9836-9843.

https://doi.org/10.1021/acs.analchem.9b01505

Evaluation of superficially porous particle based zwitterionic chiral ion exchangers against fully porous particle benchmarks for enantioselective ultra-high performance liquid chromatography

Christian Geibel, Kristina Dittrich, Ulrich Woiwode, Michal Kohout, Tong Zhang, Wolfgang Lindner, Michael Lämmerhofer

J. Chromatogr. A, 1603 (2019), 130-140.

https://doi.org/10.1016/j.chroma.2019.06.026

Derivatize, Racemize and Analyze - an Easy and Simple Procedure for Chiral Amino Acid Standard Preparation for Enantioselective Metabolomics

Jeannie Horak, Michael Lämmerhofer

Anal. Chem.,  2019, 91, 12, 7679-7689.

https://doi.org/10.1021/acs.analchem.9b00666

Functionalized gold nanoparticles for sample preparation: A review

Siyao Liu, Michael Lämmerhofer

Electrophoresis, 40 (2019), 2438-2461.

https://doi.org/10.1002/elps.201900111

Chiral separation of underivatized and 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate derivatized amino acids using zwitterionic quinine and quinidine type ZWIX columns by liquid chromatography - high-resolution mass spectrometry

Jeannie Horak, Michael Lämmerhofer

J. Chromatogr. A, 1596 (2019), 69-78.

https://doi.org/10.1016/j.chroma.2019.02.060

Stable-bond reversed-phase/weak anion-exchange mixed-mode stationary phase obtained by simultaneous functionalization and crosslinking of a poly(3-mercaptopropyl)methylsiloxane-film on vinyl silica via thiol-ene double click reaction

Stefanie Bäurer, Aleksandra Zimmermann, Ulrich Woiwode, Orlando Sánchez-Muñoz, Markus Kramer, Jeannie Horak, Michael Lämmerhofer

J. Chromatogr. A, 1593 (2019) 110-118.

https://doi.org/10.1016/j.chroma.2019.01.078

In-situ photopolymerized C4-functionalized organosilicon monoliths for reversed-phase protein separation in nano-liquid chromatography.

Çiğdem Kip, Siyao Liu, Xinhue Fu, Ali Tuncel, Michael Lämmerhofer

Talanta, 198 (2019) 330-336.

https://doi.org/10.1016/j.talanta.2019.01.116

A combined Targeted/Untargeted LC-MS/MS-based Screening Approach for Mammalian Cell Lines Treated with Ionic Liquids: Toxicity Correlates with Metabolic Profile

Corinna Sanwald, Alexandra Robciuc, Suvi-Katriina Ruokonen, Susanne K. Wiedmer, Michael Lämmerhofer

Talanta, 197 (2019) 472-481.

https://doi.org/10.1016/j.talanta.2019.01.054

Discovery of the Cyclic Lipopeptide Gacamide A by Genome Mining and Repair of the defective GacA-Regulator in Pseudomonas fluorescens Pf0-1

Gahzaleh Jahanshah, Heike Gerhardt, Zoltán Pataj, Michael Lämmerhofer, Isabelle Pianet, Markus Nett, Michaele Josten, Hans-Georg Sahl, Mark W. Silby, Joyce E. Loper, Harald Gross

J. Nat. Prod., 2019, 82, 2, 301-308.

https://doi.org/10.1021/acs.jnatprod.8b00747

Guidelines for tuning the macropore structure of monolithic columns for high-performance liquid chromatography

José Luís Dores-Sousa, Alejandro Fernández-Pumarega, Jelle De Vos, Michael Lämmerhofer, Gert Desmet, Sebastiaan Eeltink,

J. Sep. Sci., 42 (2019) 522-533.

https://doi.org/10.1002/jssc.201801092

Quantitative analysis of chemoresistance-inducing fatty acid in food supplements using UHPLC-ESI-MS/MS

Jörg Schlotterbeck, Malgorzata Cebo, Agnes Kolb, Michael Lämmerhofer

Anal. Bioanal. Chem., 411 (2019) 479-491.

https://doi.org/10.1007/s00216-018-1468-x

Comparison of simple monophasic versus classical biphasic extraction protocols for comprehensive UHPLC-MS/MS lipidomics analysis of Hela cells

Carlos Calderón, Corinna Sanwald, Jörg Schlotterbeck, Bernhard Drotleff, Michael Lämmerhofer

Anal. Chim. Acta, 1048 (2019) 66-74.

https://doi.org/10.1016/j.aca.2018.10.035

Protein A- and Protein G-Gold Nanoparticle Bioconjugates as Nano-Immunoaffinity Platform for human IgG Depletion in Plasma and Antibody Extraction from Cell Culture Supernatant

Siyao Liu, Elisabeth Haller, Jeannie Horak, Marlene Brandstetter, Thomas Heuser, Michael Lämmerhofer

Talanta, 194 (2019) 664-672.

https://doi.org/10.1016/j.talanta.2018.10.079 

Simultaneous separation of water- and fat-soluble vitamins by selective comprehensive hilic × rplc (high-resolution sampling) and active solvent modulation

Stefanie Bäurer, Wenkai Guo, Stefan Polnick, Michael Lämmerhofer

Chromatographia, 82 (2019) 167-180.

https://doi.org/10.1007/s10337-018-3615-0

Comprehensive MS/MS profiling by UHPLC-ESI-QTOF-MS/MS using swath data-independent acquisition for the study of platelet lipidomes in coronary artery disease

Jörg Schlotterbeck, Madhumita Chatterjee, Meinrad Gawaz, Michael Lämmerhofer

Anal. Chim. Acta, 1046 (2019) 1-15.

https://doi.org/10.1016/j.aca.2018.08.060

Free fatty acid profiling in marine algae extract by LC‐MS/MS and isolation as well as quantification of the ω‐3 fatty acid hexadeca‐4,7,10,13‐tetraenoic acid

 Jörg Schlotterbeck, Agnes Kolb, Michael Lämmerhofer

J. Sep. Sci., 41 (2018) 4286-4295.

https://doi.org/10.1002/jssc.201800780

Comparison of small size fully porous particles and superficially porous particles of chiral anion-exchange type stationary phases in ultra-high performance liquid chromatography: Effect of particle and pore size on chromatographic efficiency and kinetic performance

Kristina Schmitt, Ulrich Woiwode, Michal Kohout, Tong Zhang, Wolfgang Lindner, Michael Lämmerhofer

J. Chromatogr. A, 1569 (2018) 149-159.

https://doi.org/10.1016/j.chroma.2018.07.056

Zwitterionic codeine-derived methacrylate monoliths for enantioselective capillary electrochromatography of chiral acids and chiral bases

Enrique Javier Carrasco-Correa, Martina Ferri, Ulrich Woiwode, Yubo Ma, José Manuel Herrero-Martínez, Guillermo Ramis-Ramos, Wolfgang Lindner, Michael Lämmerhofer

Electrophoresis, 39 (2018) 2558-2565.

https://doi.org/10.1002/elps.201800126

Imaging peptide and protein chirality via amino acid analysis by chiral × chiral two-dimensional correlation liquid chromatography

Ulrich Woiwode, Roland Johann Reischl, Stephan Buckenmaier, Wolfgang Lindner, and Michael Lämmerhofer

Anal. Chem., 2018, 90 (13), pp 7963–7971

https://doi.org/10.1021/acs.analchem.8b00676

Complementary enantioselectivity profiles of chiral cinchonan carbamate selectors with distinct carbamate residues and their implementation in enantioselective two-dimensional high-performance liquid chromatography of amino acids

Ulrich Woiwode, Martina Ferri, Norbert M Maier, Wolfgang Lindner, Michael Laemmerhofer

J. Chromatogr. A, 1558 (2018) 29-36.

https://doi.org/10.1016/j.chroma.2018.04.061

N-Propyl-N'-2-pyridylurea-modified silica as mixed-mode stationary phase with moderate weak anion exchange capacity and pH-dependent surface charge reversal

Stefanie Baeurer, Stefan Polnick, Orlando L Sanchez-Munoz, Markus Kramer, Michael Laemmerhofer

J. Chromatogr. A, 1560 (2018) 45-54.

https://doi.org/10.1016/j.chroma.2018.05.012

Enantioselective multiple heartcut two-dimensional ultra-high-performance liquid chromatography method with a Coreshell chiral stationary phase in the second dimension for analysis of all proteinogenic amino acids in a single run

Ulrich Woiwode, Stefan Neubauer, Wolfgang Lindner, Stephan Buckenmaier, Michael Lämmerhofer

J. Chromatogr. A, 1562 (2018) 69-77.

https://doi.org/10.1016/j.chroma.2018.05.062

Quantification of Steroid Hormones in Plasma Using a Surrogate Calibrant Approach and UHPLC-ESI-QTOF-MS/MS with SWATH-Acquisition Combined with Untargeted Profiling

B. Drotleff, M. Hallschmid, M. Lämmerhofer

Anal. Chim. Acta, 1022 (2018) 70-80.

https://doi.org/10.1016/j.aca.2018.03.040

Insulin and Estrogen Independently and Differentially Reduce Macronutrient Intake in Healthy Men

R. Krug, L. Mohwinkel, B. Drotleff, J. Born, M. Hallschmid

J. Clin. Endocrinol. Metab, 103 (2018) 1393-1401

https://doi.org/10.1210/jc.2017-01835

Chiral Separation of disease biomarkers with 2-hydroxycarboxylic acid structure

Carlos Calderon, Cristina Santi, Michael Lämmerhofer

J. Sep. Sci., 41 (2018) 1224-1231

https://doi.org/10.1002/jssc.201701243

Correlation between ionic liquid cytotoxicity and liposome-ionic liquid interactions.

Suvi-Katriina Ruokonen, Corinna Sanwald, Alexandra Robciuc, Sami Hietala, Antti H. Rantamäki, Joanna Witos, Alistair W. T. King, Michael Lämmerhofer, Susanne K. Wiedmer

Chem. Eur .J., 24 (2018) 2669 –2680

http://dx.doi.org/10.1002/chem.201704924.

Response Surface Methodology for the Determination of the Design Space of Enantiomeric Separations on Cinchona-based Zwitterionic Chiral Stationary Phases by High Performance Liquid chromatography.

Rasha Sayed Hanafi, Michael Lämmerhofer

J. Chromatogr. A, 1534 (2018) 55-63

https://doi.org/10.1016/j.chroma.2017.12.044

Optimization of surface modification process of crosslinked polythiol-coated chiral stationary phases synthesized by two-step thiol-ene click reaction

Kristina Schmitt, Michael Lämmerhofer

J. Sep. Sci., 41 (2018) 1338–1345

http://dx.doi.org/10.1002/jssc.201701425

Sub-minute Separations in Enantioselective Ultra High-Performance Liquid Chromatography with Superficially Porous Chiral Stationary Phases

Ulrich Woiwode, Stefan Neubauer, Mike Kaupert, Wolfgang Lindner, Michael Lämmerhofer
Chrom+Food FORUM, 09 (2017)

Accurate and Reliable Quantification of the Protein Surface Coverage on Protein-Functionalized Nanoparticles

Siyao Liu, Jeannie Horak, Markus Höldrich, Michael Lämmerhofer

Anal. Chim. Acta, 989 (2017) 29-37.

http://dx.doi.org/10.1016/j.aca.2017.08.004

Design, Synthesis, and Biological Evaluation of Novel Type I1/2 p38α MAP Kinase Inhibitors with Excellent Selectivity, High Potency, and Prolonged Target Residence Time by Interfering with the R-Spine

Niklas M. Walter, Heike K. Wentsch, Mike Bührmann, Silke M. Bauer, Eva Döring, Svenja Mayer-Wrangowski, Adrian Sievers-Engler, Nicole Willemsen-Seegers, Guido Zaman, Rogier Buijsman, Michael Lämmerhofer, Daniel Rauh, and Stefan A. Laufer

J. Med. Chem., 60 (2017) 8027–8054.
http://dx.doi.org/10.1021/acs.jmedchem.7b00745

Trends in Enantioselective High-Performance Liquid Chromatography

Ulrich Woiwode, Stefan Neubauer, Mike Kaupert, Wolfgang Lindner, Michael Lämmerhofer
Special Issue on Recent Developments in HPLC and UHPLC (Ed. Deirdre Cabooter), Supplement to LCGC Europe / LCGC North America, June 01, 2017, Volume 30, Issue 6, 34-42.

http://www.chromatographyonline.com/trends-enantioselective-high-performance-liquid-chromatography

Preparation of Mach-Zehnder interferometric photonic biosensors by inkjet printing technology

Florian Strasser; Eva Melnik; Paul Muellner; Pilar Jiménez-Meneses; Magdalena Nechvile; Guenther Koppitsch; Peter Lieberzeit; Michael Laemmerhofer; Rudolf Heer; Rainer Hainberger

Proc. SPIE 10231, Optical Sensors 2017, 102312H (May 16, 2017)

http://dx.doi.org/10.1117/12.2267156

Trisubstituted imidazoles with a rigidized hinge binding motif act as single digit nM inhibitors of clinically relevant EGFR L858R/T790M and L858R/T790M/C797S mutants: An example of target hopping

Michael Juchum, Marcel Günther, Eva Doering, Adrian Sievers-Engler, Michael Lämmerhofer, Stefan A. Laufer

J. Med. Chem., 60 (2017) 4636-4656.

http://dx.doi.org/10.1021/acs.jmedchem.7b00178

Surface-anchored counterions on weak chiral anion-exchangers accelerate separations and improve their compatibility for mass-spectrometry-hyphenation

Ulrich Woiwode, Adrian Sievers-Engler, Aleksandra Zimmermann, Wolfgang Lindner, Orlando L. Sánchez-Muñoz, Michael Lämmerhofer

J. Chromatogr. A, 1503 (2017) 21-31.

http://dx.doi.org/10.1016/j.chroma.2017.04.054

Gold Nanoparticle-Based Immobilized Enzyme Reactors Straightforward and Accelerated Sample Preparation in Protein and Biopharmaceuticals Analysis

Siyao Liu, Markus Höldrich, Helmut Hinterwirth, Michael Lämmerhofer

Chrom+Food FORUM, 04 (2017) 12-15.

In-situ Functionalized Monolithic Polysiloxane-Polymethacrylate Composite Materials from Polythiol-Ene Double Click Reaction in Capillary Column Format for Enantioselective Nano-HPLC

Marc Wolter, Michael Lämmerhofer,

J. Chromatogr. A, 1497 (2017) 172-179.

http://dx.doi.org/10.1016/j.chroma.2017.03.070

Regulation of oxidized platelet lipidome: implications for coronary artery disease

Madhumita Chatterjee, Dominik Rath, Jörg Schlotterbeck, Johannes Rheinlaender, Britta Walker-Allgaier, Nada Alnaggar, Monika Zdanyte, Iris Müller, Oliver Borst, Tobias Geisler, Tilman E. Schäffer, Michael Lämmerhofer and Meinrad Gawaz

Eur Heart J., 38 (2017) 1993-2005.

http://dx.doi.org/10.1093/eurheartj/ehx146

Selective Targeting of G-Quadruplex Structures by a Benzothiazole-Based Binding Motif

Ina Buchholz, Beatrice Karg, Jonathan Dickerhoff, Adrian Sievers-Engler, Michael Lämmerhofer, Klaus Weisz

Chem. Eur. J., 23 (2017) 5814-5823.

http://dx.doi.org/10.1002/chem.201700298

Papain-functionalized Gold Nanoparticles as Heterogeneous Biocatalyst for Bioanalysis and Biopharmaceuticals Analysis

Siyao Liu, Markus Höldrich, Adrian Sievers-Engler, Jeannie Horak, Michael Lämmerhofer

Anal. Chim. Acta, 963 (2017) 33-43,

http://dx.doi.org/10.1016/j.aca.2017.02.009

Taylor Dispersion Analysis, Resonant Mass Measurement and Bioactivity of Pepsin-Coated Gold Nanoparticles
Markus Höldrich, Siyao Liu, Markus Epe, Michael Lämmerhofer

Talanta, 167 (2017) 67–74

http://dx.doi.org/10.1016/j.talanta.2017.02.010

Chiral Separation of Short Chain Aliphatic Hydroxycarboxylic Acids on Cinchonan Carbamate based Weak Chiral Anion Exchangers and Zwitterionic Chiral Ion Exchangers
Carlos Calderón, Michael Lämmerhofer

J. Chromatogr. A, 1487 (2017) 194–200

http://dx.doi.org/10.1016/j.chroma.2017.01.060

Tri‐ and Tetra‐substituted Pyridinylimidazoles as Covalent Inhibitors of c‐Jun N‐Terminal Kinase 3
Felix Muth, Ahmed El-Gokha, Francesco Ansideri, Michael Eitel, Eva Döring, Adrian Sievers-Engler, Andreas Lange, Frank M. Boeckler, Michael Laemmerhofer, Pierre Koch, and Stefan A. Laufer

J. Med. Chem., 60 (2017) 594–607

http://dx.doi.org/10.1021/acs.jmedchem.6b01180

Surface Modification of Integrated Optical MZI Sensor Arrays Using Inkjet Printing Technology
Eva Melnik, Florian Strasser, Paul Muellner, Rudolf Heer, Giorgio C. Mutinati, Guenther Koppitsch, Peter Lieberzeit, Michael Laemmerhofer, Rainer Hainberger

Procedia Engineering, 168 (2016) 337–340.

http://dx.doi.org/10.1016/j.proeng.2016.11.113.

Insect adhesion secretions: Similarities and dissimilarities in hydrocarbon profiles of tarsi and corresponding tibiae

Heike Gerhardt, Oliver Betz, Klaus Albert, Michael Lämmerhofer

J. Chem. Ecol., 42(2016), 725-738

http://dx.doi.org/10.1007/s10886-016-0718-7

Local functionalization of CMOS-compatible Si₃N₄ Mach-Zehnder interferometers with printable functional polymers

Eva Melnik, Paul Muellner, Giorgio Mutinati, Guenther Koppitsch, Franz Schrank, Rainer Hainberger, Michael Laemmerhofer

Sensors und Actuators B, Chemical, 236 (2016) 1061–1068

DOI: 10.1016/j.snb.2016.05.121

Effect of Ionic Liquids on Zebrafish (Danio rerio) Viability, Behavior, and Histology; Correlation between Toxicity and Ionic Liquid Aggregation.

Suvi-Katriina Ruokonen, Corinna Sanwald, Maria Sundvik, Stefan Polnick, Kashmira Vyavaharkar, Filip Duša, Ashley J. Holding, Alistair W. T. King, Ilkka Kilpeläinen, Michael Lämmerhofer, Pertti Panula, and Susanne K. Wiedmer

Environmental Science & Technology, 50 (2016), 7116–7125

DOI: 10.1021/acs.est.5b06107

Gold nanoparticle-conjugated pepsin for efficient solution-like heterogeneous biocatalysis in analytical sample preparation protocols

Markus Höldrich, Adrian Sievers-Engler, Michael Lämmerhofer

Anal. Bioanal. Chem., 408 (2016), 5415–5427

DOI: 10.1007/s00216-016-9657-y

Chiral Separation of 2-Hydroxyglutaric Acid on Cinchonan Carbamate based Weak Chiral Anion Exchangers by High-Performance Liquid Chromatography-Charged Aerosol Detector

Carlos Calderon, Jeannie Horak, Michael Lämmerhofer

J. Chromatogr. A, 1467 (2016) 239-245

DOI: 10.1016/j.chroma.2016.05.042

Surface-crosslinked poly(3-mercaptopropyl)methylsiloxane-coatings on silica as new platform for low-bleed mass spectrometry-compatible functionalized stationary phases synthesized via thiol-ene click reaction

Aleksandra Zimmermann, Jeannie Horak, Adrian Sievers-Engler, Corinna Sanwald, Wolfgang Lindner, Markus Kramer, Michael Lämmerhofer

J. Chromatogr. A, 1436 (2016) 73–83

DOI: 10.1016/j.chrima.2016.01.058

Peptide analysis: Stereoselective ion exchangers as complementary option to HILIC and to RP chromatography

Tong Zhang, Emilie Holder, Pilar Franco, Michael Lämmerhofer, Adrian Sievers-Engler, Heike Gerhardt, Harald Gross, Wolfgang Lindner

LCGC, 29 (3) (2016) 112-128

http://www.chromatographyonline.com/peptide-analysis-zwitterionic-chiral-ion-exchangers-complementary-option-hilic-and-reversed-phase-ch

Human IgG detection in serum on polymer based Mach-Zehnder interferometric biosensors

Eva Melnik, Roman Bruck, Paul Müllner, Thomas Schlederer , Rainer Hainberger, Michael Lämmerhofer

J. Biophotonics, 9 (2016) 218-223

DOI: 10.1002/jbio.201500280

Preparation of fluorescent labeled gentamicin as biological tracer and its characterization by liquid chromatography and high resolution mass spectrometry

U. Woiwode, A. Sievers-Engler, M. Lämmerhofer

J. Pharm. Biomed. Anal.,121, (2016) 307–315

DOI: 10.1016/j.jpba.2015.12.053

Methods for the comprehensive structural elucidation of constitution and stereochemistry of lipopeptides

Heike Gerhardt, Adrian Sievers-Engler, Ghazaleh Jahanshah, Zoltán Pataj, Federica Ianni, Harald Gross, Wolfgang Lindner, Michael Lämmerhofer

J. Chromatogr. A, 1428 (2016) 280–291

DOI: 10.1016/j.chroma.2015.05.065

Quinine-based zwitterionic chiral stationary phase as complementary tool for peptide analysis: Mobile phase effects on enantio- and stereoselectivity of underivatized oligopeptides

Federica Ianni, Roccaldo Sardella, Andrea Carotti, Benedetto Natalini, Wolfgang Lindner, Michael Lämmerhofer

Chirality, 28 (2016) 5–16

DOI: 10.1002/chir.22541

Mastering analytical challenges for the characterization of pentacyclic triterpene mono and diesters of Calendula officinalis flowers by non-aqueous C30 HPLC and hyphenation with APCI-QTOF-MS

Christoph Nicolaus, Adrian Sievers-Engler, Renato Murillo, Michele D’Ambrosio, Michael Lämmerhofer, Irmgard Merfort

J. Pharm. Biomed. Anal., 118 (2016) 195–205

DOI: 10.1016/j.jpba.2015.10.025

Structural and Biophysical Evaluation of the Applicability of Halogen Bonding in Molecular Design - Targeting the Gatekeeper MET146 of C-Jun N-terminal Kinase 3 (JNK3)

Andreas Lange, Marcel B. Günther, Felix Büttner, Markus O. Zimmermann, Johannes Heidrich, Susanne Hennig, Christoph Schall, Adrian Sievers-Engler, Francesco Ansideri, Pierre Koch, Michael Lämmerhofer, Thilo Stehle, Stefan A. Laufer, Frank M. Böckler

J. Am. Chem. Soc., 137 (2015) 14640-14652

DOI: 10.1021/jacs.5b07090

Review: Developments in hyphenation of isoelectric focusing with mass spectrometry
Jens Hühner, Michael Lämmerhofer, Christian Neusüß

Electrophoresis, 36 (2015) 2670-2686

DOI: 10.1002/elps.201500185

Molecular Recognition and Visual Detection of G-Quadruplexes by a Dicarbocyanine Dye
Beatrice Karg, Andrea Funke, Anna Ficht, Adrian Sievers-Engler, Michael Lämmerhofer, Klaus Weisz
Chemistry- A European Journal, 21 (2015) 13802-13811

DOI: 10.1002/chem.201502118

Investigating insect adhesion secretions by gas chromatography – mass spectrometry

Klaus Albert, Heike Gerhardt, Michael Lämmerhofer

J Chromatograph Separat Techniq, (2015) S1

DOI: 10.4172/2157-7064.S1-002

Surface charge fine tuning of reversed-phase/weak anion-exchange type mixed-mode stationary phases for milder elution conditions

Aleksandra Zimmermann, Jeannie Horak, Orlando L. Sánchez-Muñoz, Michael Lämmerhofer

J. Chromatogr. A, 1409 (2015) 189-200

DOI: 10.1016/j.chroma.2015.07.036

Digging into Biomarkers of Oxidative Stress: Hyphenated chromatography techniques enable the selection of representative biomarkers of oxidative stress – and help resolve the huge complexity of lipid oxidation products

Michael Lämmerhofer

The Analytical Scientist, July 20th, 2015| Issue #0715 (Article # 302).

Selective Sample Preparation by Carbonyl-Tagging and Nanoparticle-Based Enrichment for LC-MS/MS Analysis of Carbonylated Phospholipids as Biomarkers of Oxidative Stress
Michael Lämmerhofer, Elisabeth Haller, Wolfgang Lindner

ChromFood Forum, 06 (2015) 9-13

Staying power: Adhesives modeled on insect secretions
Heike Gerhardt and Michael Lämmerhofer
q&more 01.15, English version

www.q-more.com

Starke Haftkraft: Klebstoffe nach dem Vorbild von Insektensekreten
Heike Gerhardt, Michael Lämmerhofer

q&more 01.15, Deutsche Ausgabe

www.q-more.com

Phosphatidyl choline covalently linked to a methacrylate-based monolith as stationary phase for capillary liquid chromatography

Dana Moravcová, Enrique Javier Carrasco-Correa, Josef Planeta, Michael Lämmerhofer, Susanne K. Wiedmer

J. Chromatogr. A, 1402 (2015) 27–35

DOI: 10.1016/j.chroma.2015.05.004

The novel lipopeptide poaeamide of the endophyte Pseudomonas poae RE*1-1-14 is involved in pathogen suppression and root colonization

Christin Zachow, Ghazaleh Jahanshah, Irene de Bruijn, Chunxu Song, Federica Ianni, Zoltán Pataj, Heike Gerhardt, Isabelle Pianet, Michael Lämmerhofer, Gabriele Berg, Harald Gross, Jos M. Raaijmakers

Molecular Plant-Microbe Interactions, 28 (2015) 800-810

DOI: 10.1094/MPMI-12-14-0406-R

New insights into novel inhibitors against deoxyhypusine hydroxylase from plasmodium falciparum: Compounds with an iron chelating potential

Imke von Koschitzky, Heike Gerhardt, Michael Lämmerhofer, Michal Kohout, Matthias Gehringer, Stefan Laufer, Mario Pink, Simone Schmitz-Spahnke, Christina Strube, Annette Kaiser

Amino Acids, 47 (2015) 1155-1166

DOI: 10.1007/s00726-015-1943-z

Contact Solid-phase Microextraction with Uncoated Glass and Polydimethylsiloxane-coated Fibers versus Solvent Sampling for the Determination of Hydrocarbons in Adhesion Secretions of Madagascar Hissing Cockroaches Gromphadorrhina portentosa (Blattodea) by Gas Chromatography-Mass Spectrometry

Heike Gerhardt, Christian Schmitt, Oliver Betz, Klaus Albert, Michael Lämmerhofer

J. Chromatography A, 1388 (2015) 24-35

DOI: 10.1016/j.chroma.2015.02.027

Impact of amphiphilic biomass-dissolving ionic liquids on biological cells and liposomes

Suvi-Katriina Mikkola, Alexandra Robciuc, Jana Lokajova, Ashley Holding, Michael Lämmerhofer, Ilkka Kilpeläinen, Juha Holopainen, Alistair King, Susanne Wiedmer

Environmental Science & Technology, 49 (2015) 1870-1878

DOI: 10.1021/es505725g

Quantification of riboflavin, flavin mononucleotide and flavin adenine dinucleotide in mammalian model cells by CE with LED-induced fluorescence detection

Jens Hühner, Álvaro Ingles-Prieto, Christian Neusüß, Michael Lämmerhofer, Harald Janovjak

Electrophoresis, 36 (2015) 518-525

DOI: 10.1002/elps.201400451

Gold Nanoparticle – Antibody Bioconjugates for Specific Extraction and subsequent LC-MS/MS Analysis of Malondialdehyde-modified LDL as Biomarker for Atherosclerotic Risk Assessment

Elisabeth Haller, Wolfgang Lindner, Michael Lämmerhofer

Anal. Chim. Acta, 857 (2015) 53-63

DOI: 10.1016/j.aca.2014.12.024

Analysis of Chemical Profiles of Insect Adhesion Secretions by Gas Chromatography-Mass Spectrometry

Manuela Reitz, Heike Gerhardt, Christian Schmitt, Oliver Betz, Klaus Albert, Michael Lämmerhofer

Anal. Chim. Acta, 854 (2015) 47-60

DOI: 10.1016/j.aca.2014.10.056

Mixed-mode (RP/WAX) stationäre Phasen – Verbesserung der Selektivität bei der Reinigung und Analyse synthetischer Oligonukleotide für die Gentherapie

Aleksandra Zimmermann, Jeannie Horak, Michael Lämmerhofer

chrom+food FORUM, 09 (2014) 57-59

Polymethacrylate monoliths with immobilized poly-3-mercaptopropyl methylsiloxane film for high-coverage surface functionalization by thiol-ene click reaction

Enrique J. Carrasco Correa, Guillermo Ramis Ramos, José Manuel Herrero-Martínez, Michael Lämmerhofer

J. Chromatogr. A, 1367 (2014) 132-130

DOI: 10.1016/j.chroma.2014.09.066

Chemical Recognition of Oxidation-Specific Epitopes in Low Density Lipoproteins by a Nanoparticle based Concept for Trapping, Enrichment and LC-MS/MS Analysis of Oxidative Stress Biomarkers

ElisabethHaller, Gerald Stübiger, Daniel Lafitte, Wolfgang Lindner, Michael Lämmerhofer

Anal. Chem., 86(19) (2014) 9954–9961

DOI: 10.1021/ac502855n

Liquid chromatographic enantiomer separation with special focus on zwitterionic chiral ion-exchangers

Michael Lämmerhofer

Anal. Bioanal. Chem., 406 (2014) 6095-6103

DOI: 10.1007/s00216-014-7930-5

Synthetic oligonucleotide separation by mixed-mode reversed-phase/weak anion-exchange liquid chromatography

Aleksandra Zimmermann, Roberto Greco, Isabel Walker, Jeannie Horak, Alberto Cavazzini, Michael Lämmerhofer

J. Chromatogr. A, 1354 (2014) 43-55

DOI: 10.1016/j.chroma.2014.05.048

Target evaluation of deoxyhypusine synthase from Theileria parva the neglected animal parasite and its relationship to Plasmodium

James T. Njuguna, Imke von Koschitzky, Heike Gerhardt, Michael Lämmerhofer, Ali Choucry, Mario Pink, Simone Schmitz-Spahnke, Mohammed A. Bakheit, Christina Strube, Annette Kaiser

Bioorg. Med. Chem., 22 (2014) 4338–4346

DOI: 10.1016/j.bmc.2014.05.007

Mucin-based Stationary Phases as Tool for the Characterization of Drug - Mucus Interaction

Andrea F.G. Gargano, Michael Lämmerhofer, Hans Lönn, Peter Schoenmakers, Tomas Leek

J. Chromatogr. A., 1351 (2014) 70-81

DOI: 10.1016/j.chroma.2014.05.031

Ligand-Receptor Binding Increments in Enantioselective Liquid Chromatography

Adrian Sievers-Engler, Wolfgang Lindner, Michael Lämmerhofer

J. Chromatogr. A, 1363 (2014) 79-88

DOI: 10.1016/j.chroma.2014.04.077

Direct enantioseparation of underivatized aliphatic 3-hydroxyalkanoic acids with a quinine-based zwitterionic chiral stationary phase

Federica Ianni, Zoltán Pataj, Harald Gross, Roccaldo Sardella, Benedetto Natalini, Wolfgang Lindner, Michael Lämmerhofer

J. Chromatogr. A, 1363 (2014) 101-108

DOI: 10.1016/j.chroma.2014.03.060

Trendbericht: Analytische Chemie 2012/2013

Michael Lämmerhofer, Jürgen Popp, Suhang He, Werner Nau, Kerstin Leopold, Christine Kranz, Jürgen W. Einax, Boris Mizaikoff

Nachrichten aus der Chemie, 62(4) (2014) 407-414

DOI: 10.1002/nadc.201490115

Extract from gum resin of boswellia serrata decreases IA2-antibody in a patient with “Late onset Autoimmune Diabetes of the Adult” (LADA)

E. Schrott, S. Laufer, M. Lämmerhofer, H.P.T. Ammon

Phytomedicine, 21(6) (2014) 786

DOI: 10.1016/j.phymed.2014.02.004

Streptavidin binding as model to characterize thiol-ene chemistry based polyamine surfaces for reversible photonic protein biosensing

Eva Melnik, Paul Muellner, Ole Bethge, Emmerich Bertagnolli, Rainer Hainberger, Michael Lämmerhofer

Chem. Commun., 50(19) (2014) 2424-2427

DOI: 10.1039/c3cc48640k

Simultaneous quantification of mefloquine (+)- and (-)-enantiomers and the carboxy metabolite in dried blood spots by LC MS/MS

Mirjam C.K. Geditz, Wolfgang Lindner, Michael Lämmerhofer, Georg Heinkele, Reinhold Kerb, Michael Ramharter, Matthias Schwab, Ute Hofmann

J. Chromatogr. B, 968 (2014) 32-39

DOI: 10.1016/j.jchromb.2013.11.035

Direct high-performance liquid chromatographic enantioseparation of free α-, β- and γ-aminophosphonic acids employing cinchona-based chiral zwitterionic ion exchangers

Andrea F. G. Gargano, Michal Kohout, Pavla Macíková, Michael Lämmerhofer, Wolfgang Lindner

Anal. Bioanal. Chem., 405 (2013) 8027-8038

DOI: 10.1007/s00216-013-6938-6

Chemoaffinity material for plasmid DNA analysis by HPLC with condition-dependent switching between isoform and topoisomer selectivity

M. Mahut, A. Gargano, H. Schuchnigg, W. Lindner, M. Lämmerhofer

Anal. Chem., (2013) 2913-2920

DOI: 10.1021/ac3034823

Metabolomics in Practice, Successful Strategies to Generate and Analyze Metabolic Data

Lämmerhofer, Michael / Weckwerth, Wolfram (eds.)

1. Auflage Januar 2013

ISBN 978-3-527-33089-8 Wiley-VCH, Weinheim

Quantifying Thiol Ligand Density of Self-Assembled Monolayers on Gold Nanoparticles by Inductively Coupled Plasma Mass Spectrometry

H. Hinterwirth, S. Kappel, T. Waitz, T. Prohaska, W. Lindner and M. Lämmerhofer

ACS Nano, 7 (2013),1129-1136

DOI: 10.1021/nn306024a

Comparative method evaluation for size and size-distribution analysis of gold nanoparticles

H. Hinterwirth, S. K. Wiedmer, M. Moilanen, A. Lehner, G. Allmaier, T. Waitz, W. Lindner, M. Lämmerhofer

J. Sep. Sci., 36 (2013) 2952–2961

DOI: 10.1002/jssc.201300460

Phosphopeptidomimetic substance libraries from multicomponent reaction: Enantioseparation on quinidine carbamate stationary phase

A.F.G. Gargano, W.Lindner, M. Lämmerhofer

J. Chromatogr. A, 1310 (2013) 56– 65

DOI: 10.1016/j.chroma.2013.08.019

Mixed-mode chromatography with zwitterionic phosphopeptidomimetic selectors from Ugi multicomponent reaction

A.F.G. Gargano, T. Leek, W.Lindner, M. Lämmerhofer

J. Chromatogr. A, 1317 (2013) 12-21

DOI: 10.1016/j.chroma.2013.07.095

Gold nanoparticle-conjugated anti-oxidized low-density lipoprotein antibodies for targeted lipidomics of oxidative stress biomarkers

H. Hinterwirth, G. Stübiger, W. Lindner, M. Lämmerhofer

Anal. Chem., 85 (2013) 8376-8384

DOI: 10.1021/ac401778f

Single step Ugi Multicomponent Reaction for the synthesis of phosphopeptidomimetics

A.F.G. Gargano, S. Buchinger, M. Kohout, W. Lindner, M. Lämmerhofer

J. Org. Chem., 78 (2013) 10077–10087

DOI: 10.1021/jo401372x

Aminothiazole-featured pirinixic acid derivatives as dual 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 inhibitors with improved potency and efficiency in vivo.

T. Hanke, F. Dehm, S. Liening, S.D. Popella, J. Maczewsky, M. Pillong, J. Kunze, C. Weinigel, D. Barz, A. Kaiser, M. Wurglics, M. Lämmerhofer, G. Schneider, L. Sautebin, M. Schubert-Zsilavecz, O. Werz

J. Med. Chem., 56 (2013) 9031–9044

DOI: 10.1021/jm401557w

Special Issue: Trends 2013 (in honor of Prof. Frantisek Svec)

M. Lämmerhofer (Editor)

J. Sep. Sci., 36 (2013) 17

DOI: 10.1002/jssc.v36.17

Trends in Separation Science (editorial)

M. Lämmerhofer

J. Sep. Sci., 36 (2013)

DOI: 10.1002/jssc.201370164

Virtual Special Issue: HILIC and Mixed-modes

M. Lämmerhofer (Editor)

J. Sep. Sci.

ISSN: 1615-9314

Bioconjugation of trypsin onto gold nanoparticles: effect of surface chemistry on bioactivity

H. Hinterwirth, W. Lindner, M. Lämmerhofer

Anal. Chim. Acta, 733 (2012), 90-97

DOI: 10.1016/j.aca.2012.04.036

Trendbericht: Analytische Chemie 2010/2011

Boris Mizaikoff, Michael Lämmerhofer, José A.C. Broekaert, Jürgen Popp, Bernhard Lendl, Kerstin Leopold, Frieder W. Scheller, Aysu Yarman, Soeren Schumacher, Nicolas Plumeré, Andreas Hennig, Werner Nau, Christine Kranz, Jürgen W. Einax

Nachrichten aus der Chemie, 60 (4) (2012), 406–420
DOI: 10.1002/nadc.201290145

Activation of a silent phenazine biosynthetic gene cluster reveals a novel natural product and a new resistance mechanism against phenazines

Orwah Saleh, Tobias Bonitz, Katrin Flinspach, Andreas Kulik, Nadja Burkard, Agnes Mühlenweg, Andreas Vente, Stefan Polnick, Michael Lämmerhofer, Bertolt Gust, Hans-Peter Fiedler and Lutz Heide

MedChemComm., 3 (2012), 1009-1019

DOI: 10.1039/c2md20045g

Quantitative LC-MS/MS impurity profiling methods for the analysis of parenteral infusion solutions for amino acid supplementation containing L-Alanyl-L-Glutamine

S. Schiesel, M. Lämmerhofer, A. Leitner, W. Lindner

J. Chromatogr. A, 1259 (2012), 111-120

DOI: 10.1016/j.chroma.2012.01.020

Comprehensive impurity profiling of multi-component nutritional infusion solutions for amino acid supplementation by a multidimensional analysis assay using off-line RPLC x HILIC – ion-trap MS and charged aerosol detection with universal calibration

S. Schiesel, M. Lämmerhofer, W. Lindner

J. Chromatogr. A, 1259 (2012), 100-110

DOI: 10.1016/j.chroma.2012.01.009

Analysis of Phytosiderophore-Metal Complexes in soil related samples: CE-MS vs. LC-MS

Madeleine Dell’mour, Walter Schenkeveld, Eva Oburger, Lisa Fischer, Stephan Kraemer, Markus Puschenreiter, Michael Lämmerhofer, Gunda Koellensperger, Stephan Hann

Electrophoresis, 33 (2012), 726–733

DOI: 10.1002/elps.201100466

Molecular recognition principles and stationary phase characteristics of topoisomer-selective chemoaffinity materials for chromatographic separation of circular plasmid DNA topoisomers

Marek Mahut, Wolfgang Lindner, Michael Lämmerhofer

J. Am. Chem. Soc., 134 (2012), 859–862

DOI: 10.1021/ja210241a

Plasmid DNA manufacturing: Topology-selective chromatography reveals plasmid supercoiling shifts during fermentation and allows large-scale production of topoisomers

M. Mahut, E. Haller, P. Ghazidezfuli, M. Leitner, P. Hinterdorfer, W. Lindner, M. Lämmerhofer

Angew. Chem. Int. Ed., 51 (2012), 267-270

for the International Edition: DOI: 10.1002/anie.201106495

for the German Edition: DOI: 10.1002/ange.201106495

Time-resolved chloroquine-induced relaxation of supercoiled plasmid DNA bionanoparticles

Mahut, Marek; Leitner, Michael; Ebner, Andreas; Laemmerhofer, Michael; Hinterdorfer, Peter; Lindner, Wolfgang

Anal. Bioanal. Chem., 402 (2012), 373-380

DOI: 10.1007/s00216-011-5213-y

Optimization Strategies accounting for the Additive in Preparative Chiral Liquid Chromatography

Patrik Forssen, Lena Edström, Michael Lämmerhofer, Jörgen Samuelsson, Anders Karlsson, Wolfgang Lindner, Torgny Fornstedt

J. Chromatogr. A., 1269 (2012), 279– 286

DOI: 10.1016/j.chroma.2012.05.052

Enantioseparation of Chiral Sulfonic Acids by Liquid Chromatography and Subcritical Fluid Chromatography

Reinhard Pell, Georg Schuster, Michael Lämmerhofer, Wolfgang Lindner

J. Sep. Sci., 35 (2012), 2521 -2528

DOI: 10.1002/jssc.201200448

Enantiomer and topoisomer separation of acidic compounds on anion-exchanger chiral stationary phases by HPLC and SFC

Pilar Franco, Tong Zhang, Andrea Gargano, Marek Mahut, Michael Lämmerhofer and Wolfgang Lindner

LC-GC Europe, 25 (2012), 600-610

Article

Special Issue: Separation Science in Biotechnology

M. Lämmerhofer (Editor)

J. Sep. Sci., Volume 35, Issue 22 (2012)

DOI: 10.1002/jssc.201270182

Separation Science: Enabling Technology in Biotech (Editorial)

M. Lämmerhofer

J. Sep. Sci., 35 (2012)

DOI: 10.1002/jssc.201270183

Special Issue: Chiral Separation and Enantioselectivity

M. Lämmerhofer (Editor)

J. Chromatogr. A, 1269 (2012)

J. Chromatogr. A, 1269

Chiral Separations and Enantioselectivity (Editorial)

M. Lämmerhofer

J. Chromatogr. A, 1269 (2012), 1-2

DOI: 10.1016/j.chroma.2012.10.009

Comparison of microparticulate and monolithic columns for RP-LC of tryptic digests of industrial enzymes in cleaning products
M. Beneito-Cambra, J.M. Herrero-Martínez, G. Ramis-Ramos, W. Lindner, M. Lämmerhofer
J. Chromatogr. A, 1218 (2011), 7275-7280
DOI: 10.1016/j.chroma.2011.08.055

Multi-step surface functionalization of polyimide based evanescent wave photonic biosensors and application for DNA hybridization by Mach-Zehnder Interferometer
Eva Melnik, Roman Bruck, Rainer Hainberger, Michael Lämmerhofer
Anal. Chim. Acta, 699 (2011), 206– 215
DOI: 10.1016/j.aca.2011.05.017

Integrated polymer-based Mach-Zehnder interferometer label-free streptavidin biosensor compatible with injection molding
R. Bruck, E. Melnik, P. Muellner, R. Hainberger, M. Lämmerhofer
Biosens. Bioelectron., 26 (2011), 3832-3837
DOI: 10.1016/j.bios.2011.02.042

Multi-modal applicability of a reversed-phase/weak-anion exchange material in reversed-phase, anion-exchange, ion-exclusion, hydrophilic interaction and hydrophobic interaction chromatography modes
M. Lämmerhofer*, R. Nogueira, W. Lindner
Anal. Bioanal. Chem., 400 (2011), 2517–2530
DOI: 10.1007/s00216-011-4755-3

Simultaneous separation and analysis of water- and fat-soluble vitamins on multi-modal reversed phase – weak anion exchange material by HPLC-UV
R. Dabre, N. Azada, A. Schwämmle, M. Lämmerhofer, W. Lindner
J. Sep. Sci., 34 (2011), 761-772
DOI: 10.1002/jssc.201000793