Pharmazeutische Biologie

References

  1. Chatterjee, S., S. R. Nadkarni, E. K. Vijayakumar, M. V. Patel, B. N. Ganguli, H. W. Fehlhaber, and L. Vertesy. 1994. Napsamycins, new Pseudomonas active antibiotics of the mureidomycin family from Streptomyces sp. HIL Y-82,11372. J Antibiot (Tokyo) 47:595-598.
  2. Chen, R. H., A. M. Buko, D. N. Whittern, and J. B. McAlpine. 1989. Pacidamycins, a novel series of antibiotics with anti-Pseudomonas aeruginosa activity. II. Isolation and structural elucidation. J Antibiot (Tokyo) 42:512-520.
  3. Deb Roy, A., S. Gruschow, N. Cairns, and R. J. M. Goss. 2010. Gene expression enabling synthetic diversification of natural products: chemogenetic generation of pacidamycin analogs. J Am Chem Soc 132:12243-12245.
  4. Fernandes, P. B., R. N. Swanson, D. J. Hardy, C. W. Hanson, L. Coen, R. R. Rasmussen, and R. H. Chen. 1989. Pacidamycins, a novel series of antibiotics with anti-Pseudomonas aeruginosa activity. III. Microbiologic profile. J Antibiot (Tokyo) 42:521-526.
  5. Gruschow, S., E. J. Rackham, B. Elkins, P. L. A. Newill, L. M. Hill, and R. J. M. Goss. 2009. New pacidamycin antibiotics through precursor-directed biosynthesis. Chembiochem 10:355-360.
  6. Gust, B. 2009. Chapter 7. Cloning and analysis of natural product pathways. Methods Enzymol 458:159-180.
  7. Gust, B., G. L. Challis, K. Fowler, T. Kieser, and K. F. Chater. 2003. PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin. Proc Natl Acad Sci U S A 100:1541-1546.
  8. Gust, B., G. Chandra, D. Jakimowicz, T. Yuqing, C. J. Bruton, and K. F. Chater. 2004. Lambda red-mediated genetic manipulation of antibiotic-producing Streptomyces. Adv Appl Microbiol 54:107-128.
  9. Igarashi, M., Y. Takahashi, T. Shitara, H. Nakamura, H. Naganawa, T. Miyake, and Y. Akamatsu. 2005. Caprazamycins, novel lipo-nucleoside antibiotics, from Streptomyces sp. II. Structure elucidation of caprazamycins. J Antibiot (Tokyo) 58:327-337.
  10. Inukai, M., F. Isono, S. Takahashi, R. Enokita, Y. Sakaida, and T. Haneishi. 1989. Mureidomycins A-D, novel peptidylnucleoside antibiotics with spheroplast forming activity. I. Taxonomy, fermentation, isolation and physico-chemical properties. J Antibiot (Tokyo) 42:662-666.
  11. Isono, F., M. Inukai, S. Takahashi, T. Haneishi, T. Kinoshita, and H. Kuwano. 1989. Mureidomycins A-D, novel peptidylnucleoside antibiotics with spheroplast forming activity. II. Structural elucidation. J Antibiot (Tokyo) 42:667-673.
  12. Isono, F., T. Katayama, M. Inukai, and T. Haneishi. 1989. Mureidomycins A-D, novel peptidylnucleoside antibiotics with spheroplast forming activity. III. Biological properties. J Antibiot (Tokyo) 42:674-679.
  13. Isono, F., Y. Sakaida, S. Takahashi, T. Kinoshita, T. Nakamura, and M. Inukai. 1993. Mureidomycins E and F, minor components of mureidomycins. J Antibiot (Tokyo) 46:1203-1207.
  14. Isono, K., M. Uramoto, H. Kusakabe, K. Kimura, K. Isaki, C. C. Nelson, and J. A. McCloskey. 1985. Liposidomycins: novel nucleoside antibiotics which inhibit bacterial peptidoglycan synthesis. J Antibiot (Tokyo) 38:1617-1621.
  15. Karwowski, J. P., M. Jackson, R. J. Theriault, R. H. Chen, G. J. Barlow, and M. L. Maus. 1989. Pacidamycins, a novel series of antibiotics with anti-Pseudomonas aeruginosa activity. I. Taxonomy of the producing organism and fermentation. J Antibiot (Tokyo) 42:506-511.
  16. Kaysser, L., K. Eitel, T. Tanino, S. Siebenberg, A. Matsuda, S. Ichikawa, and B. Gust. 2010. A new arylsulfate sulfotransferase involved in liponucleoside antibiotic biosynthesis in streptomycetes. J Biol Chem 285:12684-12694.
  17. Kaysser, L., L. Lutsch, S. Siebenberg, E. Wemakor, B. Kammerer, and B. Gust. 2009. Identification and manipulation of the caprazamycin gene cluster lead to new simplified liponucleoside antibiotics and give insights into the biosynthetic pathway. J Biol Chem 284:14987-14996.
  18. Kaysser, L., S. Siebenberg, B. Kammerer, and B. Gust. 2010. Analysis of the liposidomycin gene cluster leads to the identification of new caprazamycin derivatives. Chembiochem 11:191-196.
  19. Kaysser, L., X. Tang, E. Wemakor, K. Sedding, S. Hennig, S. Siebenberg, and B. Gust. 2011. Identification of a napsamycin biosynthesis gene cluster by genome mining. Chembiochem 12:477-487.
  20. Kaysser, L., E. Wemakor, S. Siebenberg, J. A. Salas, J. K. Sohng, B. Kammerer, and B. Gust. 2010.Formation and attachment of the deoxysugar moiety and assembly of the gene cluster for caprazamycin biosynthesis. Appl Environ Microbiol 76:4008-4018.
  21. Rackham, E. J., S. Gruschow, A. E. Ragab, S. Dickens, and R. J. M. Goss. 2010. Pacidamycin biosynthesis: identification and heterologous expression of the first uridyl peptide antibiotic gene cluster. Chembiochem 11:1700-1709.
  22. Takeuchi, T., M. Igarashi, H. Naganawa, and M. Hamada. 2004. Antibiotic caprazamycins and process for producing the same. USP 6780616B1.
  23. Zhang, W., J. R. Heemstra, C. T. Walsh, and H. J. Imker. 2010. Activation of the pacidamycin PacL adenylation domain by MbtH-like proteins. Biochemistry 49:9946-9947.
  24. Zhang, W., I. Ntai, M. L. Bolla, S. J. Malcolmson, D. Kahne, N. L. Kelleher, and C. T. Walsh. 2011. Nine enzymes are required for assembly of the pacidamycin group of peptidyl nucleoside antibiotics. J Am Chem Soc 133:5240-5243.
  25. Zhang, W., B. Ostash, and C. T. Walsh. 2010. Identification of the biosynthetic gene cluster for the pacidamycin group of peptidyl nucleoside antibiotics. Proc Natl Acad Sci U S A 107:16828-16833.
  26. Zhang, Y., F. Buchholz, J. P. Muyrers, and A. F. Stewart. 1998. A new logic for DNA engineering using recombination in Escherichia coli. Nat Genet 20:123-128.

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