Zentrum für Molekularbiologie der Pflanzen (ZMBP)

Job Opportunities


Stellenangebote der Universität Tübingen

Assistant Professors / Research Group Leaders (Forschungsgruppenleiter)

 




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Postdoctoral scientists (Postdoktoranden)

29.11.21

Postdoc Position (m/f/d, E 13 TV-L, 100%)

Regulation of maize shoot apical meristem function

Center for Plant Molecular Biology, University of Tübingen, Germany

Position                                           Postdoctoral Fellow

Starting date                                 The position is available February 1, 2022

Duration                                         up to 4 years, including an initial six-months probationary period

Salary                                              At the E13 level in accordance to the guidelines of the University of

                                                           Tübingen and will dependent on previous experience and qualifications.

Project Description                     The regulatory networks underlying cell fate decisions in the shoot stem cell niche of

                                                           maize have diverged in comparison to their dicot counterparts. Taking advantage

                                                           of a high-resolution gene expression atlas for the maize apex, the project seeks to

                                                           identify factors that provide, control, or covert positional information needed to

                                                           balance stem cell proliferation and organogenesis in the maize shoot apical meristem.

                                                           The candidate will be working in an international environment, and will interact

                                                           with maize researchers across Germany.

Requirements                               Self motivated, creative, team member, background in Developmental Genetics. Experience with maize and/or use of genomics tools is advantageous.

Application                                     A single PDF that includes motivation letter, curriculum vitae, and contact

                                                           details of three referees.

Deadline                                         Applications will be accepted until the position is filled.

Inquiries and                                Marja Timmermans, PhD

address of application               Alexander von Humboldt Professor

                                                           University of Tübingen

                                                           Center for Plant Molecular Biology (ZMBP)

                                                           Auf der Morgenstelle 32, 72076 Tübingen, Germany

                                                           Email:  marja.timmermansspam prevention@zmbp.uni-tuebingen.de

Links                                                 https://www.zmbp.uni-tuebingen.de/res/developmental-genetics/timmermans/

                                                           https://genome.cshlp.org/content/29/12/1962.long

                                       https://genome.cshlp.org/content/31/5/811.long

 

The ZMBP is a world-class center for Plant Biology research and is situated in a brand-new and well-equipped building in the University of Tübingen science campus. The University of Tübingen is an equal opportunity employer and particularly welcomes applications from qualified women and individuals with disabilities.

 

 

 

 

 

21.12.20

Research: Our group at the ZMBP Tübingen is interested in the role of protein homeostasis networks in plant-microbe interactions. In our interdisciplinary group, using cell biological, biochemical and genetic approaches, we are studying the intimate interplay between protein synthesis, trafficking and degradation and how these pathways co-ordinate their functions to regulate plant immunity.

In the ERC funded project DIVERSIPHAGY we want to obtain a holistic picture of the role of autophagy in plant-microbe interactions by utilizing bacterial, genetic and cellular diversity. Our central questions are:

  • How does the bacteriome impact autophagy in shoots and roots?
  • Can we use the bacteriome to identify the autophagy degradome and autophagy factors?
  • Does cell-type specific modulation of autophagy influence plant-bacteria interactions?

Within our project, we plan to use a mixture of state-of-the-art approaches including cell biology, proteomics, metabolomics, single-cell transcriptomics and cell-type specific reverse genetic screens.

Requirements:

We are looking for Postdocs (2 positions) and PhD students (f,m,d) with proven expertise in molecular biology. For one of the postdoc position prior experiences with methods to study plant/root-microbe interactions (pathogenic or beneficial), microbial reconstitution assays (SynComs) or microbiome analysis are advantageous. For the other postdoc position expertise in general molecular biology is sufficient. Experience in cell biological approaches (microscopy) is a benefit but not required. Excellent English communication skills as well as teamwork abilities are expected. A master’s degree in molecular biology, biochemistry or corresponding is required for PhD candidates. Work within the different projects/work packages will include microbial, cell biological (confocal microscopy), biochemical (proteomics), genetic (cell-type specific CRISPR-Cas) and single-cell transcriptomic approaches using Arabidopsis and pathogenic/beneficial bacteria as model organisms. No prior experience with autophagy is required!

More information can be found on our lab homepage: http://theustunlab.com/

The positions are available from 03/2021, with a flexible start date. Reviewing of applications will begin immediately and the position will remain open until a suitable candidate is found. Please send your application by email no later than January 8th, 2021 as a composite pdf-file in English. Please include a letter of motivation with your research interests, small research idea “How does your previous work might contribute to our project?” (max ½-1 page), CV, name and addresses of at least two referees via email: suayib.uestuenspam prevention@zmbp.uni-tuebingen.de

The ZMBP is a worldclass center for Plant Biology research and is situated in a brand-new and well-equipped building in the University of Tübingen science campus. The University of Tübingen is an equal opportunity employer and particularly welcomes applications from qualified women. Equally qualified applicants with disabilities will be given preference. The employment will be carried out by the central administration of the University of Tübingen.

 

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Sorry, no open positions available


Graduate students (Doktoranden)

29.11.21

Phd position (m/f/d, TV-L E13, 65%, 3-year term)

ZMBP Developmental Genetics
Research Group Stanislas


deadline for application: 15. January 2022

With the topic: Signaling lipids regulate morphogenesis at the shoot apical meristem

In plants, the emergence of all aerial organs occurs during post-embryogenesis from an organized stem cell niche called the shoot apical meristem (SAM) The role of many biochemical regulators such as transcription factors, microRNA, hormones, and peptides as well as structural elements such as the cell wall have been extensively studied in meristem function. More specifically, it is well known that, 1) auxin accumulation induced by the polar localization of auxin carrier (PINs) and 2) microtubule organisation induced by mechanical stress generated at the peripheral zone, play a crucial role during primordium initiation.

In this DFG funded project we will aim to understand how signalling lipids at the plasma membrane regulate morphogenesis at the tissue level. For that, we developed tools to modify specifically (temporally and spatially) signalling lipids concentration at the plasma membrane. We will study their role in shoot apical meristem functions, mainly for morphogenesis, with a focus on microtubule organization in response to mechanical stress. Understanding how the lipid composition of the plasma membrane tunes protein localization and function will provide new insight into SAM regulation, especially by studying these processes at both the tissue and cell level.

We are looking for a highly motivated, self-driven candidate meeting the following requirements:

  • Degree in Cell Biology, Biochemistry or Biology with very good grades
  • Excellent communication skills in English, both written and spoken
  • Experimental creativity, cooperative and self-organized
  • Interest to integrate in an intercultural research environment

The selected candidates will use a combination of molecular biology, cell biology and biochemistry.

The ZMBP is a worldclass center for Plant Biology research and is situated in a brand-new and well-equipped building in the University of Tübingen science campus. The University of Tübingen is an equal opportunity employer and particularly welcomes applications from qualified women. Equally qualified applicants with disabilities will be given preference. The employment will be carried out by the central administration of the University of Tübingen.

For further information, please contact Dr. Thomas Stanislas (Thomas.stanislasspam prevention@zmbp.uni-tuebingen.de). Please send your application with a cover letter; curriculum vitae; certificates; letter of motivation (1-2 pages); in the form of a single pdf document by email to
Dr. Thomas Stanislas (
Thomas.stanislasspam prevention@zmbp.uni-tuebingen.de) by January 15th, 2022, or until position is filled.

 

 

 

 

15.4.21

PhD position in the NanoSignaling Lab.

A PhD position (4 years) is available in our laboratory in the Zentrum für Molekularbiologie der Pflanzen (ZMBP), University of Tübingen.

Our group uses multi-disciplinary approaches in genetics, biochemistry, and live-cell super-resolution microscopy to decipher fundamental aspects of the regulation of cell surface signaling in plants. We notably address how plasma membrane nano-environments are formed and how they orchestrate signaling.

The candidate must hold a master’s degree in biology or biochemistry. Successful candidate will be creative, ambitious, and highly motivated. Previous experience in plant biology and/or live-cell imaging will be an advantage but is not necessarily required. Excellent English written and oral skills, and team-work abilities are required. The specificities of the project will be articulated around the motivations and interests of the candidate. Current research activities relate to cell-surface receptors kinase signaling, salt sensing and evolution.

The position is preferably offered from July 2021 onwards, but an alternative starting date could be arranged. Reviewing of applications will begin immediately. The position will remain open until a suitable candidate is found. Candidates must submit a single PDF comprised of a motivation letter explaining your research interests, an up-to-date CV and the names of 2 referees to
julien.gronnierspam prevention@zmbp.uni-tuebingen.de.

PhD_position_NanoSignaling_Lab.pdf

 

 

21.12.20

Research: Our group at the ZMBP Tübingen is interested in the role of protein homeostasis networks in plant-microbe interactions. In our interdisciplinary group, using cell biological, biochemical and genetic approaches, we are studying the intimate interplay between protein synthesis, trafficking and degradation and how these pathways co-ordinate their functions to regulate plant immunity.

In the ERC funded project DIVERSIPHAGY we want to obtain a holistic picture of the role of autophagy in plant-microbe interactions by utilizing bacterial, genetic and cellular diversity. Our central questions are:

  • How does the bacteriome impact autophagy in shoots and roots?
  • Can we use the bacteriome to identify the autophagy degradome and autophagy factors?
  • Does cell-type specific modulation of autophagy influence plant-bacteria interactions?

Within our project, we plan to use a mixture of state-of-the-art approaches including cell biology, proteomics, metabolomics, single-cell transcriptomics and cell-type specific reverse genetic screens.

Requirements:

We are looking for Postdocs (2 positions) and PhD students (f,m,d) with proven expertise in molecular biology. For one of the postdoc position prior experiences with methods to study plant/root-microbe interactions (pathogenic or beneficial), microbial reconstitution assays (SynComs) or microbiome analysis are advantageous. For the other postdoc position expertise in general molecular biology is sufficient. Experience in cell biological approaches (microscopy) is a benefit but not required. Excellent English communication skills as well as teamwork abilities are expected. A master’s degree in molecular biology, biochemistry or corresponding is required for PhD candidates. Work within the different projects/work packages will include microbial, cell biological (confocal microscopy), biochemical (proteomics), genetic (cell-type specific CRISPR-Cas) and single-cell transcriptomic approaches using Arabidopsis and pathogenic/beneficial bacteria as model organisms. No prior experience with autophagy is required!

More information can be found on our lab homepage: http://theustunlab.com/

The positions are available from 03/2021, with a flexible start date. Reviewing of applications will begin immediately and the position will remain open until a suitable candidate is found. Please send your application by email no later than January 8th, 2021 as a composite pdf-file in English. Please include a letter of motivation with your research interests, small research idea “How does your previous work might contribute to our project?” (max ½-1 page), CV, name and addresses of at least two referees via email: suayib.uestuenspam prevention@zmbp.uni-tuebingen.de

The ZMBP is a worldclass center for Plant Biology research and is situated in a brand-new and well-equipped building in the University of Tübingen science campus. The University of Tübingen is an equal opportunity employer and particularly welcomes applications from qualified women. Equally qualified applicants with disabilities will be given preference. The employment will be carried out by the central administration of the University of Tübingen.

 

 

 

26.11.19

PhD Position in Plant-microbe interaction and cell biology

Research: Our group at the ZMBP Tübingen is interested in the role of the proteasome and autophagy during plant immunity. Recently, we have identified that Pseudomonas activates autophagy for proteasome degradation and enhanced pathogenicity (Üstün et al., 2018). On the contrary, another bacterial pathogen, Xanthomonas campestris pv. vesicatoria, which infects tomato plants, is using a bacterial effector protein to perturb autophagy.

In this project we aim to investigate:

  • Bacterial effectors from Xanthomonas and their impact on autophagy
  • the autophagy pathway in tomato using CRISPR/Cas9 technology
  • Bacterial effectors and their effect on endocytic degradation and vacuolar trafficking

Requirements/Qualifications:

We are looking for a talented PhD student (f,m,d) with proven expertise in cell and molecular biology. Prior experiences with methods to study plant-microbe interactions and advanced confocal microscopy are highly advantageous but not required. Excellent English communication skills as well as teamwork abilities are expected. A master’s degree in molecular biology, biochemistry or corresponding is required. We offer an innovative and scientifically stimulating environment and use a combination of state-of-the-art techniques. The work will include cell biological (confocal microscopy), biochemical (Co-IP, protein purification, protein-protein interactions), genetic and transcriptomic approaches using tomato, tobacco, Arabidopsis and Xanthomonas as model organisms.

More information can be found on our lab homepage: http://theustunlab.com/

References:

Üstün S., et al. (2018) Bacteria exploit autophagy for proteasome degradation and enhanced virulence in plants. The Plant Cell

Üstün S. et al. (2017). Autophagy as a mediator of life and death in plants. Curr Opin Plant Biol

Üstün S. and Börnke F (2014) Interactions of Xanthomonas type-III effector proteins with the plant ubiquitin and ubiquitin-like pathways. Frontiers Plant Science

The position is available immediately. Reviewing of applications will begin immediately and the position will remain open until a suitable candidate is found. Please send your application as a composite pdf-file in English (letter of motivation stating your research interests, CV, name and addresses of at least two referees) via email: suayib.uestuenspam prevention@zmbp.uni-tuebingen.de

The ZMBP is a worldclass center for Plant Biology research and is situated in a brand-new and well-equipped building in the University of Tübingen science campus. The University of Tübingen is an equal opportunity employer and particularly welcomes applications from qualified women and individuals with disabilities. Formal employment procedures will be carried out by the central administration of the University of Tübingen.

 

Permanent advertisement

 


Undergraduate students (Bachelor, Master)

 

6.11.18
 

Master Thesis Project

“Design and Characterization of a Nanosensor for In Vivo Turgor Measurements in Plant Cells”

The turgor of plant cells is crucial for plant stability and survival. Environmental cues such as drought or altered osmotic pressure lead to the change in turgor pressure having many functional consequences for the plant cell.

Therefore, the monitoring of the turgor pressure in the living plant cell is of great interest However, there is presently no technique to follow turgor changes in real time in living plant cells at cellular resolution.

Based on molecular, biochemical and biophysical considerations we, the research groups of Erik Schäffer and Klaus Harter, developed a concept and strategy for the making of a Förster Resonance Energy Transfer (FRET)-based, genetically encoded nanosensor that should facilitate the measurement of dynamic changes in the plant cell´s turgor.

The thesis work is mainly about

  • Cloning of the nanosensor gene on the basis of already available DNA fragments using the Golden Gate technology
  • Transformation of the nanosensor construct into plant cells and analysis of its expression and intracellular localization by (confocal) light microscopy
  • Determination of the nanosensor´s FRET efficiency under dynamic osmotic stress conditions using spectro-microscopical approaches (e.g. Fluorescence Lifetime Imaging: FLIM)

In addition to biology students with molecular background, the work might also be of interest for master students in Nano-Science and Biochemistry.

We offer an innovative and scientifically stimulating environment, and cutting-edge techniques. The position is available immediately.

For further information, please contact:

Prof. Dr. Klaus Harter
ZMBP/Plant Physiology

3. Etage, room 3R19

Auf der Morgenstelle 32

72076 Tübingen, Germany

+49 (0)7071 2972605

klaus.harterspam prevention@zmbp.uni-tuebingen.de

 

 

 

14.8.18

Master and or Bachelor Thesis in Plant Pathogen Interactions (RG El Kasmi)

Our research group in the Department for Plant Physiology at the Center for Plant Molecular Biology (ZMBP), University of Tübingen, is offering the possibility for a highly motivated Master and or Bachelor (of Biology, Biochemistry or Cellular Nanoscience) student to do her/his thesis project in our lab.

We are currently working on the characterization of interactors of a plant immune receptor of the NLR family. We would like to validate the preliminary results (interactions observed in yeast-2-hybrid screen) and to further cell biologically, genetically and biochemically characterize the function of the identified proteins during (NLR-mediated) immunity.
The project will include the following methods:
•    Molecular analysis (cloning, bacterial transformation, etc.)
•    In planta Protein-protein interaction studies (co-immunoprecipitation, BiFC and FRET interaction assays)
•    Genetic studies (crosses, genotyping, etc.)
•    Plant infection assays
We offer an innovative and scientifically stimulating environment, a well-equipped lab as well as an international and cooperative research team.
For applying, please send an email with a short motivation statement to Dr. Farid El Kasmi at farid.el-kasmispam prevention@zmbp.uni-tuebingen.de
For more details about the ZMBP and our research, please visit:
http://uni-tuebingen.de/fakultaeten/mathematisch-naturwissenschaftliche-fakultaet/fachbereiche/zentren/zmbp/res/plant-physiology/research-groups/elkasmi/

 

Permanent advertisement

Master and/or Bachelor Thesis in Plant Biochemistry

Our research group in the Department for Plant Biochemistry at the Center for Plant Molecular Biology (ZMBP), University of Tübingen, is seeking highly motivated Master and Bachelor students.

Our department is working on the characterization of plant immunity receptors and their regulators, as well as downstream signaling pathways.

Projects generally include the following methods:

  • Generation of plant mutants and their characterization
  • Recombinant protein expression and purification
  • In vitro and in vivo phosphorylation experiments
  • Protein-protein interaction studies (co-immunoprecipitation, yeast two-hybrid and FRET-FLIM interaction assays)
  • Molecular and physiological studies (cloning, real time-PCR, etc.)
  • Plant infection assays

We offer an innovative and scientifically stimulating environment, a well-equipped lab as well as an international and cooperative research team. You should apply if you are a biology or biochemistry student who is enthusiastic about science and keen on learning new techniques.

For applying, please send an email with a short motivation statement (attachments as pdf-files only) to andrea.gustspam prevention@zmbp.uni-tuebingen.de

For more details about the ZMBP, please visit:

http://www.zmbp.uni-tuebingen.de/zmbp.html

 



Sorry, no open positions available


Technical staff (Technische Angestellte)

 

 

 

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Student lab assistants (Wissenschaftliche Hilfskräfte)

 

 

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Administration staff (Verwaltungskräfte)

 

 

 

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Gardeners and Technical Support staff (Gärtnerei- und Werkstattpersonal, Hausmeisterei)

 

 

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Sorry, no open positions available