Center for Plant Molecular Biology

Job Opportunities


Stellenangebote der Universität Tübingen

Assistant Professors / Research Group Leaders (Forschungsgruppenleiter)

The Faculty of Science at the University of Tübingen, Department of Biology, Center for Plant Molecular Biology (ZMBP), announces the opening of a new position:

Tenure-Track Professor of Molecular Plant Biology

The position is due to commence on January 1, 2021.

The holder of this professorship is expected to develop a competitive research program in one or more of the Center for Plant Molecular Biology’s central research areas with a focus on molecular plant physiology. Further information at: www.zmbp.uni-tuebingen.de

The holder of this professorship will be expected to interact with the research units at the Center for Plant Molecular Biology (ZMBP), to be actively involved in the further development of the center, and to take on long-term responsibilities in teaching lower-level plant physiology. The position has a teaching load of four hours per week prior to an interim evaluation, and six hours thereafter. Interaction with other groups within the University of Tübingen’s Faculty of Science are also welcome.

The working group will benefit from the ZMBP’s outstanding centralized service units (administration, plant transformation, cytometry / FACS, greenhouses, analytics, spectromicroscopy, IT support).

Required qualifications include an outstanding doctorate in a pertinent field, recognizable potential for internationally acclaimed publications in leading international peer-reviewed journals and third-party funding, as well as teaching experience.
Applicants for a tenure-track professorship with a PhD from Tübingen must have changed universities after completing their doctorates or have worked in academia for at least two years somewhere other than the University of Tübingen.

If the final evaluation after six years is positive, this professorship will be upgraded to a full (W3) professorship with no re-advertising of the position. Detailed information on this employment category and the criteria underlying the interim evaluation and promotion to the tenured position may be found in our guidelines for tenure review under the following link: https://uni-tuebingen.de/en/faculties/faculty-of-science/faculty/service-downloads/#c608746

There you can also find information on this employment category. Applicants must be in an early stage of their career; those who have completed a habilitation will therefore be excluded.

The University of Tübingen is particularly interested in increasing the number of women in research and teaching and therefore strongly encourages women candidates to apply. In line with its internationalization agenda, the university welcomes applications from researchers outside Germany. In the case of equally qualified candidates, applicants with disabilities will be given preference.

Applications with supporting documents (cover letter, Curriculum Vitae, list of publications and teaching experience, certificates/diplomas) as well as a teaching statement and a research statement including collaboration plans, along with the completed application form (https://uni-tuebingen.de/en/faculties/faculty-of-science/faculty/service-downloads/#c608746) should be sent by e-mail as a single PDF file (max. 10 MB) to the Dean of the Faculty of Science, University of Tübingen, Germany (careerspam prevention@mnf.uni-tuebingen.de) by October 30, 2020. Enquiries may also be directed to this address.

 

 


--Sorry, no open positions available


Postdoctoral scientists (Postdoktoranden)

PhD and Postdoc Positions in the ERC Funded
Project: DIVERSIPHAGY

erc - European Research Council

16.11.20

ERC Postdoc and PhD 2020.pdf

Research: Our group at the ZMBP Tübingen is interested in the role of protein homeostasis networks in plant-microbe interactions. In our interdisciplinary group, using cell biological, biochemical and genetic approaches, we are studying the intimate interplay between protein synthesis, trafficking and degradation and how these pathways co-ordinate their functions to regulate plant immunity.

In the ERC funded project DIVERSIPHAGY we want to obtain a holistic picture of the role of autophagy in plant-microbe interactions by utilizing bacterial, genetic and cellular diversity. Our central questions are:

  • How does the bacteriome impact autophagy in shoots and roots?
  • Can we use the bacteriome to identify the autophagy degradome and autophagy factors?
  • Does cell-type specific modulation of autophagy influence plant-bacteria interactions?

Within our project, we plan to use a mixture of state-of-the-art approaches including cell biology, proteomics, metabolomics, single-cell transcriptomics and cell-type specific reverse genetic screens.

Requirements:

We are looking for Postdocs and PhD students (f,m,d) with proven expertise in molecular biology. For the postdoc position prior experiences with methods to study plant/root-microbe interactions (pathogenic or beneficial), microbial reconstitution assays (SynComs) or microbiome analysis are advantageous. Excellent English communication skills as well as teamwork abilities are expected. A master’s degree in molecular biology, biochemistry or corresponding is required for PhD candidates. The work will include microbial, cell biological (confocal microscopy), biochemical (proteomics), genetic (cell-type specific CRISPR-Cas) and single-cell transcriptomic approaches using Arabidopsis and pathogenic/beneficial bacteria as model organisms.

More information can be found on our lab homepage: http://theustunlab.com/

The positions are available from 03/2021. Reviewing of applications will begin immediately and the position will remain open until a suitable candidate is found. Please send your application by email no later than January 8th, 2021 as a composite pdf-file in English. Please include a letter of motivation with your research interests, small research proposal/idea (max ½-1 page), CV, name and addresses of at least two referees via email: suayib.uestuenspam prevention@zmbp.uni-tuebingen.de

The ZMBP is a worldclass center for Plant Biology research and is situated in a brand-new and well-equipped building in the University of Tübingen science campus. The University of Tübingen is an equal opportunity employer and particularly welcomes applications from qualified women. Equally qualified applicants with disabilities will be given preference. The employment will be carried out by the central administration of the University of Tübingen.

 

 

 

 

 

 

 

 

24.3.20

Bioinformatics Position

Understanding Cell Differentiation at the Single Cell level

Center for Plant Molecular Biology, University of Tübingen, Germany

Position
Postdoc or PhD Student

Starting date
flexible, but as early as July 1, 2020

Duration
3 years, including an initial six-months probationary period

Salary 
At the E13 level in accordance to the guidelines of the University of Tübingen and will dependent on previous experience and qualifications.

Project Description
The project seeks to understand the process of differentiation. Through the use of high throughput single cell RNAseq and ATACseq approaches, it will dissect the progressive changes that cells in the root and shoot of Arabidopsis undergo during their transition from stem cell through differentiation.

The candidate will be working in a team and in an international environment.

Requirements
Experience in analyses of next-generation sequencing and/or transcriptomic data, R (R studio), python and statistical analyses is required. Familiarity with wet-bench approaches such as library preparation and basic molecular techniques will be beneficial.

Application
A single PDF that includes curriculum vitae, motivation letter and contact details of three referees.

Deadline 
Applications will be accepted until the position is filled.

Inquiries and address of application
Marja Timmermans, PhD
Alexander von Humboldt Professor
University of Tübingen
ZMBP - Developmental Genetics and Cell Biology
Auf der Morgenstelle 32, 72076 Tübingen, Germany
  marja.timmermansspam prevention@zmbp.uni-tuebingen.de

Links
https://doi.org/10.1016/j.devcel.2019.02.022

https://www.zmbp-resources.uni-tuebingen.de/timmermans/plant-single-cell-browser

http://www.zmbp.uni-tuebingen.de/dev-genetics/timmermans.html

The ZMBP is a world-class center for Plant Biology research and is situated in a brand-new and well-equipped building in the University of Tübingen science campus. The University of Tübingen is an equal opportunity employer and particularly welcomes applications from qualified women and individuals with disabilities.

 

11.12.19

2 Postdoctoral Positions on the ERC Funded Project: “Knowledge Based Design of Complex Synthetic Microbial Communities”

 

Located at the Tübingen Research Campus, we are an interdisciplinary group that bridges between microbiology, plant sciences and ecology, with a strong focus on computational biology. Therefore, we are part of the Center for Plant Molecular Biology (ZMBP) and the Interfaculty Institute of Microbiology and Infection Medicine Tübingen (IMIT). Our main focus is to understand fundamental mechanisms that shape microbial communities from a stochastic input to a well-defined host-associated microbial community that protects its host from harmful intruders. Our main expertise’s are in microbiology, molecular biology and bioinformatics.

Background / Objectives

Complex microbial communities (“microbiota”) that populate surfaces of higher organisms critically impact health of their hosts: They contribute to host fitness through nutrient acquisition, stress tolerance or pathogen resistance but at the same time, can promote pathogenesis and can be reservoirs for pathogens. Mechanisms for how communities shift from a beneficial to a detrimental state are largely unknown.  
In order to cure detrimental microbiota, that were damaged through stress factors including previous diseases, decoding the complex processes governing microbiota dynamics is a key challenge. To develop durable probiotics, communal stability or the ability of a community to return to a steady state following perturbation is a key factor.
Our lab has broad expertise in studying microbial communities through lab experiments and analysing factors that shape the microbiota of Arabidopsis thaliana plants under natural conditions and common garden experiments. We have discovered a hierarchical order in microbial community networks with hub microbes as key elements. A breakthrough was the discovery of microbial taxa that persist throughout the life of A. thaliana plants and their importance in network stability. In this project we use this expertise to identify key stability factors and drivers of communal dynamics to reconstitute synthetic communities. How to seed microbial communities that develop into functional probiotics is a key challenge. We will use knowledge based assembly of complex communities to seed protective microbiota. We will challenge those through pathogens and abiotic factors to refine and test the predictive power of our analyses.

The selected candidates  will use a combination of molecular biology, microbiology, genetics and computational biology. The candidates will be involved in high throughput sequencing and computational data analyses, as well as microbial reconstitution assays. Methods will be adapted and developed according to needs for rigorously testing inferred hypotheses.

Requirements

The ideal applicant will have a doctoral degree, background in bioinformatics, molecular biology / microbiology and microbial ecology. A background in plant-microbial interactions is welcomed but not required. We seek highly motivated applicants that have extensive experience in at least one of these fields and basic knowledge in the others. Candidates with knowledge of a scripting language, experience in R and statistics background are preferred. A lab technician will be supporting these roles.

Payment / Position

All positions will be immediately available (for 36 months, renewable after evaluation). Salary and benefits are commensurate with public service organisation rules (E 13 TV-L). The University of Tübingen is an equal opportunity employer. The University seeks to raise the number of women in research and teaching and therefore urges qualified women academics to apply for these positions. Equally qualified applicants with disabilities will be given preference. The employment will be carried out by the central administration of the University of Tübingen.

Application

For questions concerning the projects please contact Prof. Eric Kemen (eric.kemenspam prevention@uni-tuebingen.de)

Please provide an application letter clearly stating which position you are applying for, including curriculum vitae, list of publications, a statement of research interests, and arrange for minimum two academic letters of recommendation to be sent by email no later than January 10th, 2020 to:
Angela Gürtel
Universität Tübingen
ZMBP / Microbial Interactions
Auf der Morgenstelle 32
D-72076 Tübingen / Germany
Phone: +49-(0)7071/29-76605
angela.guertelspam prevention@zmbp.uni-tuebingen.de

 

 

Postdoctoral Researcher (f/m) in Plant Cell Biology

We have an opening for a post-doctoral researcher in our group at the Center for Plant Molecular Biology at the University of Tübingen, Germany. If you are interested in plant cytoskeleton and its role in division plane establishment and maintenance in plants, come and join our team. Information on our research and publications is available at the ZMBP website – Developmental Genetics/Research group Müller.

We are looking for a motivated individual with expertise in cell and molecular biology. Experience with advanced confocal imaging and image analysis is an advantage. The ZMBP is a multi-national Institution and therefore English communication skills are a requirement. You will contribute to ongoing projects pertaining to division zone maintenance and phragmoplast guidance by kinesin-12 motor proteins and thus teamwork abilities are expected.

The University of Tübingen is an equal opportunity employer and particularly welcomes applications from qualified women and individuals with disabilities. Formal employment procedures will be carried out by the central administration of the University of Tübingen. Salary and benefits are according to TV-L E13 in agreement with guidelines of the University of Tübingen. Funding is secured until December 2020 and the position may be extended pending on available funding.

Please send your application, including a letter of motivation, curriculum vitae and contact information for two referees directly to
Dr. Sabine Müller: sabine.muellerspam prevention@zmbp.uni-tuebingen.de.

Screening of applications will start 30.04.2019 and will continue until the position is filled.

 

 

--

Sorry, no open positions available


Graduate students (Doktoranden)

PhD and Postdoc Positions in the ERC Funded
Project: DIVERSIPHAGY

erc - European Research Council

16.11.20

ERC Postdoc and PhD 2020.pdf

Research: Our group at the ZMBP Tübingen is interested in the role of protein homeostasis networks in plant-microbe interactions. In our interdisciplinary group, using cell biological, biochemical and genetic approaches, we are studying the intimate interplay between protein synthesis, trafficking and degradation and how these pathways co-ordinate their functions to regulate plant immunity.

In the ERC funded project DIVERSIPHAGY we want to obtain a holistic picture of the role of autophagy in plant-microbe interactions by utilizing bacterial, genetic and cellular diversity. Our central questions are:

  • How does the bacteriome impact autophagy in shoots and roots?
  • Can we use the bacteriome to identify the autophagy degradome and autophagy factors?
  • Does cell-type specific modulation of autophagy influence plant-bacteria interactions?

Within our project, we plan to use a mixture of state-of-the-art approaches including cell biology, proteomics, metabolomics, single-cell transcriptomics and cell-type specific reverse genetic screens.

Requirements:

We are looking for Postdocs and PhD students (f,m,d) with proven expertise in molecular biology. For the postdoc position prior experiences with methods to study plant/root-microbe interactions (pathogenic or beneficial), microbial reconstitution assays (SynComs) or microbiome analysis are advantageous. Excellent English communication skills as well as teamwork abilities are expected. A master’s degree in molecular biology, biochemistry or corresponding is required for PhD candidates. The work will include microbial, cell biological (confocal microscopy), biochemical (proteomics), genetic (cell-type specific CRISPR-Cas) and single-cell transcriptomic approaches using Arabidopsis and pathogenic/beneficial bacteria as model organisms.

More information can be found on our lab homepage: http://theustunlab.com/

The positions are available from 03/2021. Reviewing of applications will begin immediately and the position will remain open until a suitable candidate is found. Please send your application by email no later than January 8th, 2021 as a composite pdf-file in English. Please include a letter of motivation with your research interests, small research proposal/idea (max ½-1 page), CV, name and addresses of at least two referees via email: suayib.uestuenspam prevention@zmbp.uni-tuebingen.de

The ZMBP is a worldclass center for Plant Biology research and is situated in a brand-new and well-equipped building in the University of Tübingen science campus. The University of Tübingen is an equal opportunity employer and particularly welcomes applications from qualified women. Equally qualified applicants with disabilities will be given preference. The employment will be carried out by the central administration of the University of Tübingen.

 

 

24.3.20

Bioinformatics Position

Understanding Cell Differentiation at the Single Cell level

Center for Plant Molecular Biology, University of Tübingen, Germany

Position
Postdoc or PhD Student

Starting date
flexible, but as early as July 1, 2020

Duration
3 years, including an initial six-months probationary period

Salary 
At the E13 level in accordance to the guidelines of the University of Tübingen and will dependent on previous experience and qualifications.

Project Description
The project seeks to understand the process of differentiation. Through the use of high throughput single cell RNAseq and ATACseq approaches, it will dissect the progressive changes that cells in the root and shoot of Arabidopsis undergo during their transition from stem cell through differentiation.

The candidate will be working in a team and in an international environment.

Requirements
Experience in analyses of next-generation sequencing and/or transcriptomic data, R (R studio), python and statistical analyses is required. Familiarity with wet-bench approaches such as library preparation and basic molecular techniques will be beneficial.

Application
A single PDF that includes curriculum vitae, motivation letter and contact details of three referees.

Deadline 
Applications will be accepted until the position is filled.

Inquiries and address of application
Marja Timmermans, PhD
Alexander von Humboldt Professor
University of Tübingen
ZMBP - Developmental Genetics and Cell Biology
Auf der Morgenstelle 32, 72076 Tübingen, Germany
  marja.timmermansspam prevention@zmbp.uni-tuebingen.de

Links
https://doi.org/10.1016/j.devcel.2019.02.022

https://www.zmbp-resources.uni-tuebingen.de/timmermans/plant-single-cell-browser

http://www.zmbp.uni-tuebingen.de/dev-genetics/timmermans.html

The ZMBP is a world-class center for Plant Biology research and is situated in a brand-new and well-equipped building in the University of Tübingen science campus. The University of Tübingen is an equal opportunity employer and particularly welcomes applications from qualified women and individuals with disabilities.

 

26.11.19

PhD Position in Plant-microbe interaction and cell biology

Research: Our group at the ZMBP Tübingen is interested in the role of the proteasome and autophagy during plant immunity. Recently, we have identified that Pseudomonas activates autophagy for proteasome degradation and enhanced pathogenicity (Üstün et al., 2018). On the contrary, another bacterial pathogen, Xanthomonas campestris pv. vesicatoria, which infects tomato plants, is using a bacterial effector protein to perturb autophagy.

In this project we aim to investigate:

  • Bacterial effectors from Xanthomonas and their impact on autophagy
  • the autophagy pathway in tomato using CRISPR/Cas9 technology
  • Bacterial effectors and their effect on endocytic degradation and vacuolar trafficking

Requirements/Qualifications:

We are looking for a talented PhD student (f,m,d) with proven expertise in cell and molecular biology. Prior experiences with methods to study plant-microbe interactions and advanced confocal microscopy are highly advantageous but not required. Excellent English communication skills as well as teamwork abilities are expected. A master’s degree in molecular biology, biochemistry or corresponding is required. We offer an innovative and scientifically stimulating environment and use a combination of state-of-the-art techniques. The work will include cell biological (confocal microscopy), biochemical (Co-IP, protein purification, protein-protein interactions), genetic and transcriptomic approaches using tomato, tobacco, Arabidopsis and Xanthomonas as model organisms.

More information can be found on our lab homepage: http://theustunlab.com/

References:

Üstün S., et al. (2018) Bacteria exploit autophagy for proteasome degradation and enhanced virulence in plants. The Plant Cell

Üstün S. et al. (2017). Autophagy as a mediator of life and death in plants. Curr Opin Plant Biol

Üstün S. and Börnke F (2014) Interactions of Xanthomonas type-III effector proteins with the plant ubiquitin and ubiquitin-like pathways. Frontiers Plant Science

The position is available immediately. Reviewing of applications will begin immediately and the position will remain open until a suitable candidate is found. Please send your application as a composite pdf-file in English (letter of motivation stating your research interests, CV, name and addresses of at least two referees) via email: suayib.uestuenspam prevention@zmbp.uni-tuebingen.de

The ZMBP is a worldclass center for Plant Biology research and is situated in a brand-new and well-equipped building in the University of Tübingen science campus. The University of Tübingen is an equal opportunity employer and particularly welcomes applications from qualified women and individuals with disabilities. Formal employment procedures will be carried out by the central administration of the University of Tübingen.

 

 

13.8.19

PhD position in Molecular Biology and Biophysic

General interest: Most biological processes involve changes in molecular and cell shapes, and such deformations, in essence, involve a mechanical component. But how a mechanical stress is perceived and how this signal is transduced into the cell to exert these effects is still poorly understood, and remains challenging questions in both the plant and animal community.
Among the structural components of plant cells (cell wall, cytoskeleton…), the plasma membrane has received very little attention. Our group at the ZMBP Tübingen investigates the role of membrane lipids at the nexus between plant morphogenesis and mechanics using Arabidopsis as a model. For more information, visit our website "Stanislas Lab ZMBP“.

PhD project: In order to understand at the molecular level, the role of the lipid composition of the PM for mechano-sensing, it is needed to simplify the system. This will allow to test a wide range of hypothesis and to clearly make a link between a mechanical stimulus and a molecular response.
The selected PhD candidate will have to develop a microfluidic device to induce and quantify of mechanical signals at the cell level.

References:
A phosphoinositide map at the shoot apical meristem in Arabidopsis thaliana, Stanislas T, Platre M, Liu M, Rambaud L, Jaillais Y, Hamant H, BMC Biology, 16:20 (2018)
In-vivo analysis of morphogenesis in plants Stanislas T, Hamant O, Traas J, Methods in Cell Biology, 139:203-223 (2017)
A PtdIns(4)P-driven electrostatic field controls cell membrane identity and signalling in plants. Simon ML, Platre MP, Marques Bueno MM, Armengot L, Stanislas T, Bayle V, Caillaud MC, Jaillais Y, Nature Plant, 20, 2, 16089 (2016)


Requirements/Qualifications: We are looking for highly motivated candidates with a master degree in biology, engineering sciences, nanotechnology, biophysics or equivalent. Specific skills in microfluidics is highly advantageous. Prior experience with confocal microscopy is a plus but not required. Good English communication skills as well as excellent teamwork abilities are expected.
The position is available immediately. Application will be accepted until the position is filled. Please send your application in English as a composite pdf-file (letter of motivation stating your research interests, CV, name and addresses of at least two referees) to thomas.stanislasspam prevention@zmbp.uni-tuebingen.de

The ZMBP is a world‐class center for Plant Biology research and is situated in a brand-new and well-equipped building in the University of Tübingen science campus. The University of Tübingen is an equal opportunity employer and particularly welcomes applications from qualified women and individuals with disabilities. Formal employment procedures will be carried out by the central administration of the University of Tübingen.

 

 

Permanent advertisement

Am Zentrum für Molekularbiologie der Pflanzen (ZMBP), Abt. Entwicklungsgenetik, werden hochmotivierte

Doktorand(inn)en

Bachelor

für DFG-finanzierte Projekte zu den Themen Zellpolarität, Zellkommunikation, Cytokinese gesucht.

Weitere Information in: Weijers et al., 2006, Dev. Cell 10, 265; Geldner et al., 2003, Cell 112, 219; Richter et al., 2007, Nature 448, 488; Reichardt et al., 2007, Curr. Biol. (in press).

Erfahrungen in Genetik, Molekularbiologie, Proteinbiochemie oder Zellbiologie sowie gute Englisch-Kenntnisse sind erwünscht. Bitte senden Sie Ihre Bewerbung mit der Angabe von 3 möglichen Referenzen per email an:

Prof. Dr. Gerd Jürgens, ZMBP-Entwicklungsgenetik, Universität Tübingen,

Auf der Morgenstelle 32, 72076 Tübingen, Tel. 07071/29 78887,

e-mail: gerd.juergens(at)zmbp.uni-tuebingen.de

Permanent advertisement

The Center for Molecular Biology of Plants, Developmental Genetics, is seeking highly qualified

PhD students

Bachelor or MSc students

in the areas of cell polarity, cell-cell communication, cytokinesis (DFG-funded projects). For more information, see Weijers et al., 2006, Dev. Cell 10, 265; Geldner et al., 2003, Cell 112, 219; Richter et al., 2007, Nature 448, 488; Reichardt et al., 2007, Curr. Biol. (in press).

The successful candidates are highly motivated, proficient in English and experienced in genetics, molecular biology, cell biology or biochemistry. Please send your application including names of 3 potential referees by e-mail to:

Prof. Dr. Gerd Jürgens, ZMBP-Entwicklungsgenetik, Universität Tübingen,

Auf der Morgenstelle 32, 72076 Tübingen, Tel. 07071/29 78887,

e-mail: gerd.juergens(at)zmbp.uni-tuebingen.de


Undergraduate students (Bachelor, Master)

9.12.19

The Timmermans research group has an opening for a Masters Thesis project:

High-throughput CRISPR-CAS screening for small RNA mobility factors

During this project, you will learn how to:

  • set up and manage a reverse genetic screen.
  • use gateway cloning, and create genetically stable plant lines.
  • use genome editing by the CRISPR-CAS system.
  • take advantage of high-throughput amplicon sequencing for mutant identification.
  • use proximity labeling of proteins using TurboID.
  • write a master thesis in the style of a research journal article and to present your results to the scientific community.

MicroRNAs (miRNAs) are a class of non-coding small RNAs involved in a wide range of biological processes. Plants use miRNAs as signaling molecules to control developmental processes similar to morphogens in animals. Despite their central importance, it is still unknown how miRNAs move from one cell to another. We recently showed that miRNA mobility is regulated at individual cell-cell interfaces1. However, the molecular mechanism of this regulation is not understood. Solving this question will be the focus of the master project.
We are an international research group located in the ZMBP. During your stay, you will interact with experienced researchers who will provide supervision and ensure a productive training period. You will gain experience with cutting-edge technologies and, after an initial training period, will be able to work independently. Of course, help is always at hand. The project is set up and a preferable starting period is the beginning of 2020. If you are interested, please send your CV and brief introduction outlining your goals and interests to Simon Klesen.
1Skopelitis, Damianos S., et al. "Gating of miRNA movement at defined cell-cell interfaces governs their impact as positional signals." Nature communications 9.1 (2018): 3107.
Timmermans research group: https://uni-tuebingen.de/de/63353
Contact person: simon.klesenspam prevention@uni-tuebingen.de

 

6.11.18
 

Master Thesis Project

“Design and Characterization of a Nanosensor for In Vivo Turgor Measurements in Plant Cells”

The turgor of plant cells is crucial for plant stability and survival. Environmental cues such as drought or altered osmotic pressure lead to the change in turgor pressure having many functional consequences for the plant cell.

Therefore, the monitoring of the turgor pressure in the living plant cell is of great interest However, there is presently no technique to follow turgor changes in real time in living plant cells at cellular resolution.

Based on molecular, biochemical and biophysical considerations we, the research groups of Erik Schäffer and Klaus Harter, developed a concept and strategy for the making of a Förster Resonance Energy Transfer (FRET)-based, genetically encoded nanosensor that should facilitate the measurement of dynamic changes in the plant cell´s turgor.

The thesis work is mainly about

  • Cloning of the nanosensor gene on the basis of already available DNA fragments using the Golden Gate technology
  • Transformation of the nanosensor construct into plant cells and analysis of its expression and intracellular localization by (confocal) light microscopy
  • Determination of the nanosensor´s FRET efficiency under dynamic osmotic stress conditions using spectro-microscopical approaches (e.g. Fluorescence Lifetime Imaging: FLIM)

In addition to biology students with molecular background, the work might also be of interest for master students in Nano-Science and Biochemistry.

We offer an innovative and scientifically stimulating environment, and cutting-edge techniques. The position is available immediately.

For further information, please contact:

Prof. Dr. Klaus Harter
ZMBP/Plant Physiology

3. Etage, room 3R19

Auf der Morgenstelle 32

72076 Tübingen, Germany

+49 (0)7071 2972605

klaus.harterspam prevention@zmbp.uni-tuebingen.de

 

 

 

14.8.18

Master and or Bachelor Thesis in Plant Pathogen Interactions (RG El Kasmi)

Our research group in the Department for Plant Physiology at the Center for Plant Molecular Biology (ZMBP), University of Tübingen, is offering the possibility for a highly motivated Master and or Bachelor (of Biology, Biochemistry or Cellular Nanoscience) student to do her/his thesis project in our lab.

We are currently working on the characterization of interactors of a plant immune receptor of the NLR family. We would like to validate the preliminary results (interactions observed in yeast-2-hybrid screen) and to further cell biologically, genetically and biochemically characterize the function of the identified proteins during (NLR-mediated) immunity.
The project will include the following methods:
•    Molecular analysis (cloning, bacterial transformation, etc.)
•    In planta Protein-protein interaction studies (co-immunoprecipitation, BiFC and FRET interaction assays)
•    Genetic studies (crosses, genotyping, etc.)
•    Plant infection assays
We offer an innovative and scientifically stimulating environment, a well-equipped lab as well as an international and cooperative research team.
For applying, please send an email with a short motivation statement to Dr. Farid El Kasmi at farid.el-kasmispam prevention@zmbp.uni-tuebingen.de
For more details about the ZMBP and our research, please visit:
http://uni-tuebingen.de/fakultaeten/mathematisch-naturwissenschaftliche-fakultaet/fachbereiche/zentren/zmbp/res/plant-physiology/research-groups/elkasmi/

 

Permanent advertisement

Master and/or Bachelor Thesis in Plant Biochemistry

Our research group in the Department for Plant Biochemistry at the Center for Plant Molecular Biology (ZMBP), University of Tübingen, is seeking highly motivated Master and Bachelor students.

Our department is working on the characterization of plant immunity receptors and their regulators, as well as downstream signaling pathways.

Projects generally include the following methods:

  • Generation of plant mutants and their characterization
  • Recombinant protein expression and purification
  • In vitro and in vivo phosphorylation experiments
  • Protein-protein interaction studies (co-immunoprecipitation, yeast two-hybrid and FRET-FLIM interaction assays)
  • Molecular and physiological studies (cloning, real time-PCR, etc.)
  • Plant infection assays

We offer an innovative and scientifically stimulating environment, a well-equipped lab as well as an international and cooperative research team. You should apply if you are a biology or biochemistry student who is enthusiastic about science and keen on learning new techniques.

For applying, please send an email with a short motivation statement (attachments as pdf-files only) to andrea.gustspam prevention@zmbp.uni-tuebingen.de

For more details about the ZMBP, please visit:

http://www.zmbp.uni-tuebingen.de/zmbp.html

 



Sorry, no open positions available


Technical staff (Technische Angestellte)

 

19.12.19

ERC Projekt:

“Knowledge Based Design of Complex Synthetic Microbial Communities”

Wir sind eine internationale, interdisziplinäre Gruppe mit Sitz auf dem Tübinger Forschungscampus und verknüpfen die Mikrobiologie mit den Pflanzenwissenschaften und der Ökologie. Wir sind sowohl Teil des Zentrums für Molekularbiologie der Pflanzen (ZMBP) als auch des Interfakultären Instituts für Mikrobiologie und Infektionsmedizin Tübingen (IMIT).

Vom nächstmöglichen Zeitpunkt bis 28.02.2024 ist eine Vollzeitstelle (100%) für eine/n

Technische/n Assistentin/en (w/m/d) befristet zu besetzen.

Hintergrund / Ziele des Projekt
In diesem Projekt nutzen wir unsere Expertise im Umgang mit synthetischen mikrobiellen Gemeinschaften, um wichtige Stabilitätsfaktoren und Treiber der Dynamik dieser Gemeinschaften zu identifizieren. Zu klären wie man mikrobielle Gemeinschaften zusammensetzt um sie als Präbiotika zum Schutz des Wirtsorganismus einsetzt, ist eine zentrale Herausforderung. Wir werden komplexer mikrobielle Gemeinschaften wissensbasierte Zusammenstellen und als Probiotika gegen verschieden Pathogene auf Pflanzen testen. Neben biotischen Faktoren werden wir auch abiotische testen um die Vorhersagekraft unserer Analysen zu verfeinern und zu testen.

Wünschenswert wären:

  • Fähigkeit zur eigenverantwortlichen und selbstständigen Arbeit
  • Kenntnis mikrobiologischer, molekularbiologischer und biochemischer Methoden
  • Erfahrung beim Umgang mit Pflanzen
  • Sehr gute Kommunikation in englischer Sprache

Zur Ihren Aufgaben gehören:

  • Kultivierung und Isolierung von Mikroorganismen
  • Steriles Arbeiten mit Pflanzen
  • Hoch Durchsatz Sequenzierung (next generation sequenzing)
  • Allgemeine und sonstige projektspezifische Laboraufgaben

Wenn wir Ihr Interesse geweckt haben, dann richten Sie bitte bis zum 10.01.2020 Ihre vollständige Bewerbung als eine zusammengefasste pdf-Datei per E-Mail an unser Sekretariat: angela.guertel@zmbp.uni-tuebingen.de

Die Vergütung erfolgt je nach den persönlichen Voraussetzungen bis E9 TV-L. Schwerbehinderte werden bei gleicher Eignung bevorzugt berücksichtigt. Die Stelle ist grundsätzlich teilbar. Die Einstellung erfolgt über die Zentrale Verwaltung.

Für Auskünfte stehen wir Ihnen jederzeit gerne zur Verfügung: Prof. Eric Kemen eric.kemen@uni-tuebingen.de

Angela Gürtel
Universität Tübingen
ZMBP / Microbial Interactions
Auf der Morgenstelle 32
D-72076 Tübingen / Germany
+49-(0)7071/29-76605
angela.guertelspam prevention@zmbp.uni-tuebingen.de

 

 

 

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Sorry, no open positions available


Student lab assistants (Wissenschaftliche Hilfskräfte)

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Administration staff (Verwaltungskräfte)

 

 

 

- Sorry, no open positions available
 

 

 


Gardeners and Technical Support staff (Gärtnerei- und Werkstattpersonal, Hausmeisterei)

 



8.6.2020
Das Zentrum für Molekularbiologie der Pflanzen an der Universität Tübingen sucht zum
1. Oktober 2020 für die stellvertretende Leitung seiner Pflanzenanzucht eine/n

Gärtnermeister/in oder Agrarwissenschaftler/in

(je nach den persönlichen Voraussetzungen bis E 9 TV-L). Die Stelle ist zunächst auf
50 % des regulären Tätigkeitsumfangs angelegt. Langfristig ist eine Erhöhung auf bis zu
100 % und eine Übernahme der Leitung geplant.

Das Aufgabengebiet umfasst (in Zusammenarbeit mit der Leitung der Pflanzenanzucht)
die selbstständige und eigenverantwortliche Organisation der Abteilung einschließlich der
arbeitssicherheitsrelevanten Belange, Führung der Mitarbeiter/innen sowie den
technischen Betrieb der Klimakammern, der Gewächshäuser und des Versuchsfelds mit
seinen zugehörigen landwirtschaftlichen Maschinen. Die verantwortliche Betreuung
unserer Pflanzenkulturen (wie Arabidopsis, Zitrus, Paprika, Lotus, Cuscuta, Tomate,
Tabak, Mais) und Pflanzenschutzmaßnahmen stehen dabei im Mittelpunkt der Tätigkeit.

Für diese herausfordernden Aufgaben wird eine hohe psychische und physische
Belastbarkeit erwartet, eine abgeschlossene gärtnerische (Meister) oder agrarwissenschaftliche
Ausbildung sowie Erfahrung im Umgang mit den am ZMBP verwendeten
Kulturen. Ein technisches Grundverständnis für den Betrieb der Klimakammern und
Gewächshäuser wird ebenso benötigt wie die Fähigkeit zur Personalführung. Darüber
hinaus sind die Bereitschaft zur turnusmäßigen Durchführung von Wochenenddiensten,
Erfahrungen im Umgang mit landwirtschaftlichen Maschinen sowie IT-Kenntnisse
unverzichtbar. Aufgrund des internationalen Arbeitsumfelds am ZMBP sind grundlegende
englische Sprachkenntnisse unerlässlich.

Schwerbehinderte werden bei gleicher Eignung bevorzugt berücksichtigt.

Bitte richten Sie Ihre Bewerbung mit den üblichen Unterlagen bis 11. Juli 2020 an:
Universität Tübingen, ZMBP-Pflanzenanzucht, Auf der Morgenstelle 32, 72076 Tübingen,
per E-Mail (bitte in einer pdf-Datei) an: johanna.schroeterspam prevention@zmbp.uni-tuebingen.de

Die Einstellung erfolgt durch die Zentrale Verwaltung der Universität.

 

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Sorry, no open positions available