Living organisms evolved sophisticated surveillance systems to monitor and adapt to changes in their environment. Our group uses multi-disciplinary approaches in genetics, biochemistry, and live-cell super-resolution microscopy to decipher fundamental aspects of the regulation of cell surface signaling in plants. Lipids and proteins are dynamically organized into diverse membrane nano-environments giving rise to fluid molecular patchworks. In plants, these structures are named nanodomain. We address how plasma membrane nano-environments are formed, how they orchestrate signaling and how regulatory mechanisms and associated functions evolved.
