Interfakultäres Institut für Mikrobiologie und Infektionsmedizin

Compound Purification

Bacterial extracts are prepared from biomass or culture filtrates. Versatile chromatography systems are available to separate compounds by hydrophobic, hydrophilic or ionic interactions, also by special affinity chromatography or size exclusion.

Fractionation in microtiter plates is established, to provide sample plates ready for testing.

Proprietary databases are employed for sample deconvolution and identification of novel chemical entities. Custom made data dereplication software and integrated data management are established and allow for effective compound determination.