The Interfaculty Institute of Biochemistry (IFIB) is a vertically integrated research center covering all dimensions of modern biochemical research from atoms via molecules and cells to organisms. The Stehle- Hartmann labs make proteins visible at the atomic level. Stafforst and Schwarzer with co-workers modify molecules directly to investigate nucleic acids and histones. The groups of Dodt, Jansen and Rapaport investigate the workings of the cell, looking at peroxisomes, RNA, and mitochondria, respectively. Beyond the level of cells, the lozano-Duran- and Nürnberger labs shed light on how whole organisms like plants defend themselves. The Feil lab listens in on how mouse cells communicate with each other, and Schulze-Osthoff and his team investigate what happens when the organism's own cells go berserk and turn into tumors.