Computational Systems Biology

Fatma Ece Altınışık Kaya

M.Sc. in Bioingenieurwesen

Fatma Ece Altınışık Kaya
Büro

Fachbereich Informatik
Institut für Biomedizinische Informatik
Sand 14 ･ Erdgeschoss ･ Raum C106
  +49-7071-29-70488
 +49-7071-29-5152
fatma-ece.altinisik-kayaspam prevention@student.uni-tuebingen.de

Bibliographie

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Soziale Medien

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Akademische Qualifikationen

  • Seit Oktober 2022: Gastdoktorandin
    Institut für Biomedizinische Informatik (IBMI) in Tübingen

  • Seit 2018: Doktorandin
    Marmara-Universität, Institut für weiterführende Studien der Naturwissenschaften und deren Anwendung, Fachbereich Bioingenieurwesen, Türkei

  • 2014-2017: Masterstudium
    Marmara-Universität, Institut für weiterführende Studien der Naturwissenschaften und deren Anwendung, Fachbereich Bioingenieurwesen, Türkei

  • 2010-2014: Bachelorstudium
    Marmara-Universität, Fakultät für Ingenieurwesen, Bioingenieurwesen, Türkei

Forschungsinteressen

  • Reonstruktion von Stoffwechselmodellen im Genom-Maßstab

  • Systembiologie

  • Biotechnologie

  • Bioprozesse

  • Rekombinante Enzymproduktion und -aufreinigung

Publikationen

  1. Can Genome Sequencing Coupled to Flux Balance Analyses Offer Precision Guidance for Industrial Strain Development? The Lessons from Carbon Trafficking in Corynebacterium glutamicum ATCC 21573
    Eldin Kurpejović, Daniel Wibberg, Gülsüm Merve Bastem, Arthur Burgardt, Tobias Busche, Fatma Ece Altınışık Kaya, Andreas Dräger, Volker F. Wendisch und Berna Sarıyar Akbulut
    OMICS: A Journal of Integrative Biology, 27:9, 14. September 2023.
    [ Details | DOI | PDF | PubMed | BibTeX ]
  2. Identification of novel inhibitors of the ABC transporter BmrA
    Serçinoğlu O., Senturk D., Altinisik K.,Avci F., Frlan R., Tomašič T., Uzbek P., Orelle C., Jault J., Sariyar Akbulut B.
    BIOORGANICCHEMISTRY, vol. 105, 2020
    [ DOI | PubMed ]
  3. What Are the Multi-Omics Mechanisms for Adaptation by Microorganisms to High Alkalinity? A Transcriptomic and Proteomic Study of a Bacillus Strain with Industrial Potential
    Altinisik Kaya F.E., Avci F.G., Sayar N.A., Kazan D., Sayar A.A., Sariyar Akbulut B.
    OMICS:A JOURNAL OF INTEGRATIVE BIOLOGY, vol. 22 , no.11, pp. 717-732, 2018
    [ DOI | PubMed ]
  4. Targeting a hidden site on class A beta-lactamases
    Avci F. G., Altinisik Kaya F. E., Karacan I., Karagoz D. S., Ersahin S., Eren A., Sayar N. A., Ulu D. V., Özkirimli Ölmez E., Sariyar Akbulut B.
    JOURNAL OF MOLECULAR GRAPHICS & MODELLING, vol. 84, pp.125-133, 2018
    [ DOI | PubMed ]
  5. Transcriptomic analysis displays the effect of (-)-roemerine on the motility and nutrient uptake in Escherichia coli
    Ayyildiz D., Arga K. Y., Avci F. G., Altinisik Kaya F. E., Gurer C., Toplan G. G., Kazan D., Wozny K., Bruegger B., Mertoglu B., et al.
    CURRENT GENETICS, vol. 63, no.4, pp. 709-722, 2017
    [ DOI | PubMed ]
  6. An evolutionarily conserved allosteric site modulates beta-lactamase activity
    Avci F. G., Altinisik Kaya F. E., Vardar Ulu D., Özkirimli Ölmez E., Sariyar Akbulut B.
    JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 31, pp. 33-40, 2016
    [ DOI | PubMed ]
  7. Evaluation of silibinin as an efflux pump inhibitor in Bacillus subtilis
    Altinisik Kaya F. E., Atas B., Avci F. G.
    International Journal of Secondary Metabolite, vol. 8, no.2, pp.104-112, 2021
    [ DOI | PubMed ]

Vorträge

  1. Understanding the metabolic reprogramming behind alkaliphilic adaptation in Bacillus marmarensis through a multi-omics data integration strategy
    Altınışık Kaya F .E., Arğa K.Y., Kazan D., Sarıyar Akbulut B.
    44th FEBSCongress: From molecules to living systems, Krakow, Poland, 6-11Juli 2019

Poster-Präsentationen

  1. Can DapC be the missing aminotransferease in the arogenate route of L-tyrosine biosynthesis in Corynebacterium glutamicum?
    Altinisik Kaya F.E., Kurpejovic E., Burgardt A., Wendisch V.F., Sariyar Akbulut B.
    FEBS OPEN BIO, vol.12, pp.180-181, 2022

  2. New inhibitors of the BmrA pump identified through virtual screening
    Senturk D., Sercinoglu O., Altinisik Kaya F.E., Frlan R., Tomasi T., Avci F.G., Özbek Sarica P., Orelle C., Jault J.M., Sariyar Akbulut B.
    MuTaLig COST ACTION CA15135 4th WG meeting, 5. März 2020

  3. Understanding alkaliphilic adaptation of Bacillus marmarensis sp nov
    Altinisik Kaya F.E., Avci F.G., Denizci A.A.,Kazan D., Sariyar Akbulut B.
    FEBS 2016, 3.-8. September 2016, vol. 283, pp.127-427

  4. Investigation of proteome profile of alkaliphilic B. marmarensis sp nov under different pH conditions
    Altinisik Kaya F.E., Avci F.G., Denizci A.A.,Kazan D., Sariyar Akbulut B
    FEBS BIOINTERACTOMICS, 17.-20. Mai 2016

  5. Mutations of a conserved tryptophan residue of the TEM-1 beta-lactamase
    Altinisik Kaya F.E., Avci F.G., Sariyar Akbulut B., Özkirimli Ölmez E., Ulu D.V., Karacan I., Senturk D.
    29th Annual Symposium of the Protein Society, Barcelona, Spanien, 22.-25. Juli 2015, vol. 24, pp. 175