30.07.2021

Co-organization of the 6th annual SysMod meeting of the ISMB/ECCB.

Tübingen‘s systems biology team contributes to shaping the international systems modeling gathering.

The annual ISMB conference (“Intelligent Machines for Molecular Biology”) retook place in 2021 under corona conditions as a virtual event in combination with the European Bioinformatics Conference (ECCB). Since the foundation of the associated Symposium on Systems Modeling (SysMod) in 2016, the Tübingen working group on systems biology has contributed significantly to the organization and design of this event.

Members of the working group gave two talks:

• Dr. Reihaneh Mostolizadeh: “Workflow for modeling microbial community interactions applied to Dolosigranulum pigrum and Staphylococcus aureus within the human nose.”
• Nantia Leonidou: “Tissue-specific reconstruction of constraint-based metabolic models based on ReconX.”

Moreover, the working group was involved in the preparation of two others:

• Dawson D. Payne: “An updated genome-scale metabolic network reconstruction of Pseudomonas aeruginosa PA14 to characterize mucin-driven shifts in bacterial metabolism.”
• Sanjeev Dahal: “Genome-scale modeling of Pseudomonas aeruginosa PA14 unveils its broad metabolic capabilities and role of metabolism in virulence and drug potentiation.”

Jun.-Prof. Dr. Andreas Dräger chaired the session on “Infectious disease modeling.”

In addition, the Tübingen working group presented further results in the form of three scientific posters:

• Martina Feierabend: “High-quality genome-scale reconstruction of Corynebacterium glutamicum ATCC 13032.”
• Alina Renz: “Curating and Comparing 114 Strain-Specific Genome-Scale Metabolic Models of Staphylococcus aureus.”
• Jun.-Prof. Dr. Andreas Dräger: “The Systems Biology Simulation Core Library.”

The next event on SysMod is planned to take place in 2022 again as a conference with face-to-face lectures if conditions allow.