Uni-Tübingen

B6: Proteasome inhibitors from Nocardia ssp. and their role in pathogen survival

Group Leader

Jun.-Prof. Leonard Kaysser
German Centre for Infection Research (DZIF)
Department of Pharmaceutical Biology
Eberhard-Karls-Universität Tübingen
Auf der Morgenstelle 8
72076 Tübingen
Phone: +49-7071 29-77671
Fax: +49-7071 29-5250
Email: leonard.kaysser(at)uni-tuebingen.de

PhD Student

Alicia Engelbrecht
Phone: +49-7071 29-77 671
email: alicia.engelbrecht(at)student.uni-tuebingen.de

Summary

• Identification of proteasome inhibitors from pathogenic Nocardia spp. and structural characterization
• Evaluation of bioactive properties of newly identified proteasome inhibitors
• Investigation of the role of proteasome inhibitors in immune evasion and virulence of the Nocardia producer strains