Uni-Tübingen

Subproject A09: Räumliche und zeitliche Regulation spezifischer membranassoziierter Prozesse.

Teilprojektleiter:

Dr. Julien Gronnier
Universität Tübingen
ZMBP, Allgemeine Genetik
Auf der Morgenstelle 32
72076 Tübingen
+49 7071 29 74608

 

Zusammenfassung:

REMORIN-Proteine haben sich als Regulatoren der Nanodomänen-Organisation erwiesen. Sie finden sich in unterschiedlichen Membran-Nanodomänen (NDs), von denen man annimmt, dass sie verschiedene Signalkomplexe beherbergen. Mittels Verbindung von Genetik, Biochemie und Superresolutions- Mikroskopie möchten wir REMORIN-NDs beschreiben und funktionell charakteri-sieren. Des Weiteren soll der molekulare Mechanismus, der den Gruppe 1-REMORINs im Kontext von Salzstress zugrunde liegt, entschlüsselt werden. Dieses Projekt wird den Weg zu einem mechanis-tischen Verständnis der Bildung und der Funktion spezifischer Membran-Nanoumgebungen ebnen.

 

 

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