Uni-Tübingen

Subproject B12: Molekulare Spezifität von BSK Proteinen in MAP Kinase Signalwegen

Hauptuntersuchungsleiter:

Dr. Martin Bayer
Universität Tübingen
ZMBP, Entwicklungsgenetik
Auf der Morgenstelle 32
72076 Tübingen
 +49 7071 29 78888
martin.bayerspam prevention@zmbp.uni-tuebingen.de

Zusammenfassung:

Proteine der BRASSINOSTEROID SIGNALING KINASE (BSK) Familie arbeiten als phosphorylierungsabhängige Adaptermoleküle in SERK-abhängigen Signalwegen der Pflanzenentwicklung und Immunantwort. In diesem Projekt werden wir im Kontext des ERECTA Signalwegs untersuchen, welche Rolle BSK Proteine bei der selektiven Aktivierung von MAP3K Proteinen spielen. Des Weiteren werden wir anhand des ERECTA-, des FLS2- und des HAESA-LIKE1 Signalwegs untersuchen, wie sich die Signalantwort dieser Prototyp-Signalwege der Pflanzenentwicklung und Immunantwort unterscheiden und wie Spezifität erzeugt wird.

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