Publications


Year of Publication: 2024

FROG Analysis Ensures the Reproducibility of Genome Scale Metabolic Models

Karthik Raman, Miroslav Kratochvíl, Brett G. Olivier, Matthias König, Pratyay Sengupta, Dinesh Kumar Kuppa Baskaran, Tung V. N. Nguyen, Daniel Lobo, St Elmo Wilken, Krishna Kumar Tiwari, Aswathy K. Raghu, Indumathi Palanikumar, Lavanya Raajaraam, Maziya Ibrahim, Sanjaay Balakrishnan, Shreyanash Umale, Frank T. Bergmann, Tanisha Malpani, Venkata P. Satagopam, Reinhard Schneider, Moritz E. Beber, Sarah M. Keating, Mihail Anton, Alina Renz, Meiyappan Lakshmanan, Dong-Yup Lee, Lokanand Koduru, Reihaneh Mostolizadeh, Oscar Dias, Emanuel Cunha, Alexandre Oliveira, Yi Qing Lee, Karsten Zengler, Rodrigo Santibáñez-Palominos, Manish Kumar, Matteo Barberis, Bhanwar Lal Puniya, Tomáš Helikar, Hoang V. Dinh, Patrick F. Suthers, Costas D. Maranas, Isabella Casini, Seyed Babak Loghmani, Nadine Veith, Nantia Leonidou, Feiran Li, Yu Chen, Jens Nielsen, GaRyoung Lee, Sang Mi Lee, Gi Bae Kim, Pedro T. Monteiro, Miguel C. Teixeira, Hyun Uk Kim, Sang Yup Lee, Ulf W. Liebal, Lars M. Blank, Christian Lieven, Chaimaa Tarzi, Claudio Angione, Manga Enuh Blaise, Çelık Pinar Aytar, Mikhail Kulyashov, llya Akberdin, Dohyeon Kim, Sung Ho Yoon, Zhaohui Xu, Jyotshana Gautam, William T. Scott, Peter J. Schaap, Jasper J. Koehorst, Cristal Zuñiga, Gabriel Canto-Encalada, Sara Benito-Vaquerizo, Ivette Parera Olm, Maria Suarez-Diez, Qianquian Yuan, Hongwu Ma, Mohammad Mazharul Islam, Jason A. Papin, Francisco Zorrilla, Kiran Raosaheb Patil, Arianna Basile, Juan Nogales, Granado San León, Freddy Castillo-Alfonso, Roberto Olivares-Hernández, Gabriel Vigueras-Ramírez, Henning Hermjakob, Andreas Dräger, and Rahuman S. Malik-Sheriff
BioRxiv, September, 26th, 2024
[ Details | DOI | PDF | PubMed | BibTeX ]

Bioinformatics Advances

Perspectives on computational modeling of biological systems and the significance of the SysMod community

Bhanwar Lal Puniya, Meghna Verma, Chiara Damiani, Shaimaa Bakr, and Andreas Dräger
Bioinformatics Advances, 26th 2024
[ Details | DOI | PDF | PubMed |  BibTeX ]

Microbiology Spectrum


Year of Publication: 2023

Genome-scale metabolic model of Staphylococcus epidermidis ATCC 12228 matches in vitro conditions

Nantia Leonidou, Alina Renz, Benjamin Winnerling, Anastasiia Grekova, Fabian Grein, and Andreas Dräger
BioRxiv, December, 20th, 2023.
[ Details | DOI | PreprintPDF | PubMed | BibTeX ]

Metabolic Modeling Elucidates Phenformin and Atpenin A5 as Broad-Spectrum Antiviral Drugs

Alina Renz, Mirjam Hohner, Maximilian Breitenbach, Jonathan Josephs-Spaulding, Johanna Dürrwald, Lena Best, Raphaël Jami, Georgios Marinos, Nantia Leonidou, Filipe Cabreiro, Andreas Dräger, Michael Schindler, and Christoph Kaleta
Preprints 2023, November, 30th 2023.
[ Details | DOI | PDF | PubMed | BibTeX ]

Genome-scale metabolic models consistently predict in vitro characteristics of Corynebacterium striatum

Famke BäuerleGwendolyn O. Döbel, Laura Camus, Simon Heilbronner, and Andreas Dräger
Frontiers in Bioinformatics, Section Network Bioinformatics, October, 23rd 2023.
[ Details | DOIPreprint | PDF | PubMedBibTeX ]

An integrated systems-biology approach reveals differences in formate metabolism in the genus Methanothermobacter

Isabella Casini, Tim McCubbin, Sofia Esquivel-Elizondo, Guillermo G. Luque, Daria Evseeva, Christian Fink, Sebastian Beblawy, Nicholas D. Youngblut, Ludmilla Aristilde, Daniel H. Huson, Andreas Dräger, Ruth E. Ley, Esteban Marcellin, Largus T. Angenent, and Bastian Molitor
iScience, September 22nd, 2023
[ Details | DOI | Preprint | PDF | PubMed | BibTeX ]

Can Genome Sequencing Coupled to Flux Balance Analyses Offer Precision Guidance for Industrial Strain Development? The Lessons from Carbon Trafficking in Corynebacterium glutamicum ATCC 21573

Eldin Kurpejović, Daniel Wibberg, Gülsüm Merve Bastem, Arthur Burgardt, Tobias Busche, Fatma Ece Altınışık KayaAndreas Dräger, Volker F. Wendisch, and Berna Sarıyar Akbulut
OMICS: A Journal of Integrative Biology, 27:9, September 14th, 2023.
[ DetailsDOI | PDF | PubMed | BibTeX ]

Advancements in Computational Modelling of Biological Systems: seventh annual SysMod meeting

Bhanwar Lal Puniya and Andreas Dräger
Bioinformatics, 14. September 2023.
[ DetailsDOI | PDF | PubMed | BibTeX ]

Standard-GEM: Standardization of open-source genome-scale metabolic models

Mihail Anton,  Eivind Almaas, Rui Benfeitas, Sara Benito-Vaquerizo, Lars M. Blank, Andreas Dräger, John M. Hancock, Cheewin Kittikunapong, Matthias König, Feiran Li, Ulf W. Liebal, Hongzhong Lu, Hongwu Ma, Radhakrishnan Mahadevan, Adil Mardinoglu, Jens Nielsen, Juan Nogales, Marco Pagni, Jason A. Papin, Kiran Raosaheb Patil, Nathan D. Price, Jonathan L. Robinson, Benjamín J. Sánchez, Maria Suarez Diez, Snorre Sulheim, L. Thomas Svensson, Bas Teusnik, Wanwipa Vongsangnak, Hao Wang, Ahmad A. Zeidan, and Eduard J. Kerkhoven.
BioRxiv, March 23rd, 2023
[ Details | DOI | PDF | BibTeX ]

Genome-scale model of Pseudomonas aeruginosa metabolism unveils virulence and drug potentiation

Sanjeev Dahal, Alina Renz, Andreas Dräger, and Laurence Yang
Communications Biology, 6, 165, February 10th, 2023.
Details | DOIPreprint | PDF | PubMedBibTeX ]


Year of Publication: 2022

Towards the human nasal microbiome: simulating D. pigrum and S. aureus

Reihaneh MostolizadehManuel Glöckler, and Andreas Dräger
Frontiers in Cellular and Infection Microbiology 2022, October 11th, 2022
[ DetailsDOI | PDF | PubMedBibTeX ]

Computational modelling in health and disease. Highlights of the 6th annual SysMod meeting

Anna Niarakis, Juilee Thakar, Matteo Barberis, María Rodríguez Martínez, Tomáš Helikar, Marc Birtwistle, Claudine Chaouiya, Laurence Calzone, and Andreas Dräger
Bioinformatics, September 22nd, 2022.
Details | DOI | PDF | PubMed | BibTeX ]

FluxomicsExplorer: Differential visual analysis of flux sampling based on metabolomics

Constantin Holzapfel, Miriam Hoene, Xinjie Zhao, Chunxiu Hu, Cora Weigert, Andreas Nieß, Guowang Xu, Rainer Lehmann, Andreas Dräger, and Michael Krone
Computers & Graphics, August 29th, 2022
[ DetailsDOI | PDF | PubMed | BibTeX ]

A Computational Model of Bacterial Population Dynamics in Gastrointestinal Yersinia enterocolitica Infections in Mice

Janina K. Geißert, Erwin Bohn, Reihaneh Mostolizadeh, Andreas Dräger, Ingo B. Autenrieth, Sina Beier, Oliver Deusch, Alina Renz, Martin Eichner, and Monika S. Schütz.
Biology, 11(2), 297; February 12th, 2022.
Details | DOIPreprintPDF | PubMed | BibTeX ]

The Systems Biology Simulation Core Library

Hemil Panchiwala, Shalin Shah, Hannes Planatscher, Mykola Zakharchuk, Matthias König, and Andreas Dräger.
Bioinformatics, Volume 38, Issue 3, Pages 864-865, February 1st, 2022.
Details | DOI | Preprint | PubMed | PDF | BibTeX ]


Year of Publication: 2021

High-Quality Genome-Scale Reconstruction of Corynebacterium glutamicum ATCC 13032

Martina Feierabend, Alina Renz, Elisabeth Zelle, Katharina Nöh, Wolfgang Wiechert, and Andreas Dräger
Frontiers in Microbiology, November 15th 2021.
[ DetailsDOI | PDF | PubMed | BibTeX ]

COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms

Marek Ostaszewski, Anna Niarakis, Alexander Mazein, Inna Kuperstein, Robert Phair, Aurelio Orta-Resendiz, Vidisha Singh, Sara Sadat Aghamiri, Marcio Luis Acencio, Enrico Glaab, Andreas Ruepp, Gisela Fobo, Corinna Montrone, Barbara Brauner, Goar Frishman, Luis Cristóbal Monraz Gómez, Julia Somers, Matti Hoch, Shailendra Kumar Gupta, Julia Scheel, Hanna Borlinghaus, Tobias Czauderna, Falk Schreiber, Arnau Montagud, Miguel Ponce de Leon, Akira Funahashi, Yusuke Hiki, Noriko Hiroi, Takahiro G. Yamada, Andreas Dräger, Alina Renz, Muhammad Naveez, Zsolt Bocskei, Francesco Messina, Daniela Börnigen, Liam Fergusson, Marta Conti, Marius Rameil, Vanessa Nakonecnij, Jakob Vanhoefer, Leonard Schmiester, Muying Wang, Emily E. Ackerman, Jason E. Shoemaker, Jeremy Zucker, Kristie L. Oxford, Jeremy Teuton, Ebru Kocakaya, Gökçe Yağmur Summak, Kristina Hanspers, Martina Kutmon, Susan Coort, Lars Eijssen, Friederike Ehrhart, Rex D. A. B., Denise Slenter, Marvin Martens, Robin Haw, Bijay Jassal, Lisa Matthews, Marija Orlic-Milacic, Andrea Senff-Ribeiro, Karen Rothfels, Veronica Shamovsky, Ralf Stephan, Cristoffer Sevilla, Thawfeek Mohamed Varusai, Jean-Marie Ravel, Rupsha Fraser, Vera Ortseifen, Silvia Marchesi, Piotr Gawron, Ewa Smula, Laurent Heirendt, Venkata Satagopam, Guanming Wu, Anders Riutta, Martin Golebiewski, Stuart Owen, Carole Goble, Xiaoming Hu, Rupert Overall, Dieter Maier, Angela Bauch, John A. Bachman, Benjamin M Gyori, Carlos Vega, Valentin Grouès, Miguel Vazquez, Pablo Porras, Luana Licata, Marta Iannuccelli, Francesca Sacco, Denes Turei, Augustin Luna, Ozgun Babur, Sylvain Soliman, Alberto Valdeolivas, Marina Esteban-Medina, Maria Peña-Chilet, Tomáš Helikar, Bhanwar Lal Puniya, Anastasia Nesterova, Anton Yuryev, Anita de Waard, Dezso Modos, Agatha Treveil, Marton Laszlo Olbei, Bertrand De Meulder, Aurélien Naldi, Aurélien Dugourd, Vincent Noël, Laurence Calzone, Chris Sander, Emek Demir, Tamas Korcsmaros, Tom C. Freeman, Franck Augé, Jacques S. Beckmann, Jan Hasenauer, Olaf Wolkenhauer, Egon Willighagen, Alexander R. Pico, Chris Evelo, Marc Gillespie, Lincoln D. Stein, Henning Hermjakob, Peter DʼEustachio, Julio Saez-Rodriguez, Joaquin Dopazo, Alfonso Valencia, Hiroaki Kitano, Emmanuel Barillot, Charles Auffray, Rudi Balling, Reinhard Schneider, and the COVID-19 Disease Map Community
Molecular Systems Biology 17: e10387, October 19th 2021.
Details | DOI | Preprint | PubMedPDF | BibTeX ]

An updated genome-scale metabolic network reconstruction of Pseudomonas aeruginosa PA14 to characterize mucin-driven shifts in bacterial metabolism

Dawson D. Payne, Alina Renz, Laura J. Dunphy, Taylor Lewis, Andreas Dräger, and Jason A. Papin
npj Systems Biology and Applications 7, 37, October 8th 2021.
Details | DOIPreprint | PubMedPDF | BibTeX ]

SysMod: the ISCB community for data-driven computational modelling and multi-scale analysis of biological systems

Andreas Dräger, Tomáš Helikar, Matteo Barberis, Marc Birtwistle, Laurence Calzone, Claudine Chaouiya, Jan Hasenauer, Jonathan R. Karr, Anna Niarakis, María Rodríguez Martínez, Julio Saez-Rodriguez, and Juilee Thakar.
Bioinformatics, btab229, 24th 2021.
Details | DOI | Preprint | PubMed | PDF | BibTeX ]


Year of Publication: 2020

FBA reveals guanylate kinase as a potential target for antiviral therapies against SARS-CoV-2

Alina RenzLina Widerspick, and Andreas Dräger.
Bioinformatics, Volume 36, Issue Supplement_2, December 29th 2020, Pages i813-i821.
Details | DOIZenodo | PubMed | YouTube | PDF | BibTeX ]

Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells and plasmablasts as hallmarks of severe COVID-19 trajectories

Joana P. Bernardes, Neha Mishra, Florian Tran, Thomas Bahmer, Lena Best, Johanna I. Blase, Dora Bordoni, Jeanette Franzenburg, Ulf Geisen, Jonathan Josephs-Spaulding, Philipp Köhler, Axel Künstner, Elisa Rosati, Anna C. Aschenbrenner, Petra Bacher, Nathan Baran, Teide Boysen, Burkhard Brandt, Niklas Bruse, Jonathan Dörr, Andreas Dräger, Gunnar Elke, David Ellinghaus, Julia Fischer, Michael Forster, Andre Franke, Sören Franzenburg, Norbert Frey, Anette Friedrichs, Janina Fuß, Andreas Glück, Jacob Hamm, Finn Hinrichsen, Marc P. Höppner, Simon Imm, Ralf Juenker, Sina Kaiser, Ying H. Kan, Rainer Knoll, Christoph Lange, Georg Laue, Clemes Lier, Matthias Lindner, Georgios Marinos, Robert Markewitz, Jacob Nattermann, Rainer Noth, Peter Pickkers, Klaus F. Rabe, Alina Renz, Christoph Röcken, Jan Rupp, Annika Schaffarzyk, Alexander Scheffold, Jonas Schulte-Schrepping, Domagoj Schunck, Dirk Skowasch, Thomas Ulas, Klaus-Peter Wandinger, Michael Wittig, Johannes Zimmermann, Hauke Busch, Bimba F. Hoyer, Christoph Kaleta, Jan Heyckendorf, Matthijs Kox, Jan Rybniker, Stefan Schreiber, Joachim Schultze, and Philip Rosenstiel.
Immunity, November 26th 2020.
Details | DOIMedRxiv | PDF | PubMed | BibTeX  ]

Genome-Scale Metabolic Modeling of Escherichia coli and Its Chassis Design for Synthetic Biology Applications

Bashir Sajo Mienda and Andreas Dräger.
Computational Methods in Synthetic Biology. Mario Andrea Marchisio (editor), part of the series Methods in Molecular Biology (MIMB, volume 2189), pp. 217-229, November 13th 2020.
Details | DOI | PubMed | PDF | BibTeX ]

Overview: Standards for Modeling in Systems Medicine

Andreas Dräger and Dagmar Waltemath
Systems Medicine. Integrative, Qualitative and Computational Approaches. Olaf Wolkenhauer (Editor), Volume 3, 2021, Pages 245–353, August 28th 2020.
[ Details | DOI | PDF | PubMed | BibTeX ]

Clinical Applications of Metabolic Models in SBML Format

Alina Renz, Reihaneh Mostolizadeh, and Andreas Dräger
Reference Module in Biomedical Sciences, Elsevier, Januar 30th 2020
[ Details | DOI | PDF | PubMed | BibTeX ]

The Systems Biology Graphical Notation: Current Status and Applications in Systems Medicine

Vasundra Touré, Andreas Dräger, Augustin Luna, Ugur Dogrusoz, and Adrien Rougny
Reference Module in Biomedical Sciences, Elsevier, Januar 25th 2020
[ Details | DOI | PDF | PubMed | BibTeX ]


Year of Publication: 2019

BiGG Models 2020: multi-strain genome-scale models and expansion across the phylogenetic tree

Charles J. Norsigian, Neha Pusarla, John Luke McConn, James T. Yurkovich, Andreas Dräger, Bernhard O. Palsson, and Zachary King
Nucleic Acids Research, gkz1054, November 7th 2019
[ Details | DOI | PDF | PubMed | BibTeX ]


Year of Publication: 2018


Year of Publication: 2017


Year of Publication: 2016


Year of Publication: 2015


Year of Publication: 2014


Year of Publication: 2013


Year of Publication: 2012


Year of Publication: 2011


Year of Publication: 2010


Year of Publication: 2009


Year of Publication: 2008


Year of Publication: 2007