Negative feedback is a crucial component of neuronal networks that stabilizes activity, dramatically extends dynamical repertoire, and helps to implement various computations. One of the most common types of negative feedback in brain circuits is neural inhibition.
In this project we are looking at how various excitatory-inhibitory network compositions affect neuronal dynamics. More specifically, we are modelling spontaneous activity of cultured hippocampal networks with precisely controlled excitatory-inhibitory composition.
