Natural Product Projects in Tübingen

Diverse projects on natural products or natural-product-derived congeners are pursued in Tübingen, often with antibacterial focus. While for some of the compounds in-depth evaluation of antibacterial potency and target elucidation is still in progress, others have already proven substantial efficacy in rodent infection models and target interactions are well understood. The following list shows selected progressed examples:

 ADEP antibiotics: Unprecedented target and potent anti-persister activity

 Lugdunin: An antibiotic from the human nose shapes the microbiome

Glycopeptides: Bioengineering for novel derivatives and improved production yields

• Home
• Strain collection
• Strain cultivation and fermentation
• Compound purification
• Structure elucidation
• Biological characterization
• Projects
• Research groups​​​​​​​