AG Microbial Cell Wall & Glycobiology

We have currently an open PhD position: https://uni-tuebingen.de/de/108817

Research in our group is located in the intercept between chemistry & biology.
Our major goal is to understand the structure and function of the bacterial cell envelope at the molecular level and our research currently focuses on the physiology and biochemistry of the bacterial cell wall recycling and amino sugar metabolism: 

• Elucidation of cell wall recycling and amino sugar catabolic pathways
• Identification of novel enzymes acting on peptidoglycan and teichoic acids
• Structure and mechanism of enzymes involved in the bacterial cell wall turnover & recycling
• Protein and metabolic engineering
  
  Some of our current projects are:
• Cellular responses to the antibiotic fosfomycin
• Cell wall recycling metabolism in Gram-negative (Escherichia coli, Pseudomonas sp.) and Gram-positive bacteria (Bacillus subtilis, Staphylococcus aureus)
• Cell lysis and consumption during cannibalistic growth of Bacillus subtilis
• Cell wall metabolism of the oral pathogen Tannerella forsythia
• Structure and mechanism of MurNAc-6P etherase and MurNAc-1P uridylyl transferase
• WTA catabolism