The four-lane Bundesstraße B27 leads directly from the motorway 8 (Autobahn 8) to Tübingen.
→ take the 2nd exit in the direction to Böblingen/Lustnau
→ at the 3rd crossroads turn left into Wilhelmstraße
→ follow this road which will later be called Mohlstraße, then Haußer- and finally Hölderlinstraße
→ turn left at the crossroads Gmelinstraße and reaching Wilhelmstraße turn left again. The Hegel-building is at number 36 (next to the university library).
For more options see the main university website.