ZMBP Project Group Ulrike Zentgraf
Leaf senescence of annual plants

 Research | Group members | Publications | Resources

• Andrade Galan, A.G., Doll. J., Saile, S.C., Wünsch, M., Roepenack-Lahaye, E.V., Pauwels, L., Goossens, A., Bresson, J., Zentgraf U.: The Non-JAZ TIFY Protein TIFY8 of Arabidopsis thaliana Interacts with the HD-ZIP III Transcription Factor REVOLUTA and Regulates Leaf Senescence. Int. J. Mol. Sci. 24(4):3079 (2023). doi: 10.3390/ijms24043079.
• Vatov, E., Zentgraf, U., Ludewig, U.: Moderate DNA methylation changes associated with nitrogen remobilization and leaf senescence in Arabidopsis. J. Exp. Bot. 73(11): 4733–4752 (2022), doi.org/10.1093/jxb/erac167
• Bresson, J., Doll, J., Vasseur, F., Stahl, M., von Roepenack-Lahaye, E., Kilian, J., Stadelhofer, B., Kremer, J.M., Kolb, D., Wenkel, S., Zentgraf, U.: The genetic interaction of REVOLUTA and WRKY53 links plant development, senescence, and immune responses. PLoS One 17(3):e0254741 (2022) doi: 10.1371/journal.pone.0254741
• Zentgraf, U., Andrade-Galan, A.G., Bieker S.: Specificity of H2O2 signaling in leaf senescence: is the ratio of H2O2 contents in different cellular compartments sensed in Arabidopsis plants? Cell. Mol. Biol. Lett. 27:4 (2022) doi.org/10.1186/s11658-021-00300-w
• Zentgraf, U.; Andrade, A.G.; Doll, J.: Editorial for Special Issue “Leaf Senescence” in Plants. Plants 10, 1490 (2021) doi.org/10.3390/plants10081490
• Vatov, E.; Ludewig, U.; Zentgraf, U.: Disparate Dynamics of Gene Body and cis-Regulatory Element Evolution Illustrated for the Senescence-Associated Cysteine Protease Gene SAG12 of Plants. Plants 10, 1380 (2021). doi.org/10.3390/plants10071380
• Hong, S., Botterweg-Paredes, E., Doll, J., Eguen, T., Blaakmeer, A., Matton, S., Xie, Y., Lunding, B.S., Zentgraf, U., Guan, C., Jiao, Y., Wenkel, Stephan: Multi-level analysis of the interactions between REVOLUTA and MORE AXILLARY BRANCHES 2 in controlling plant development reveals parallel, independent and antagonistic functions. Development 147, 183681 (2020) doi: 10.1242/dev.183681
• Doll, J., Muth, M., Riester, L., Nebel, S., Bresson, J., Lee, H-C., Zentgraf, U.: Arabidopsis thaliana WRKY25 Transcription Factor Mediates Oxidative Stress Tolerance and Regulates Senescence in a Redox-Dependent Manner. Front. Plant Sci. 10, 1734 (2020) doi: 10.3389/fpls.2019.01734
• Zentgraf, U., Doll, J.: Arabidopsis WRKY53, a Node of Multi-Layer Regulation in the Network of Senescence. Plants 8(12), 578 (2019) doi.org/10.3390/plants8120578
• Riester, L., Köster-Hofmann, S., Doll, J., Berendzen, K.W., Zentgraf, U.: Impact of Alternatively Polyadenylated Isoforms of ETHYLENE RESPONSE FACTOR4 with Activator and Repressor Function on Senescence in Arabidopsis thaliana L. Genes 10(2), 91 (2019) doi: 10.3390/genes10020091
• Zentgraf, U.: Tug-of-war during senescence. Nat. Plants 5, 129-130 (2019) doi: 10.1038/s41477-019-0369-0.
• Bieker, S., Riester, L., Doll, J., Franzaring, J., Fangmeier, A., Zentgraf, U.: Nitrogen Supply Drives Senescence-Related Seed Storage Protein Expression in Rapeseed Leaves. Genes 10(2), 72 (2019) doi: 10.3390/genes10020072
• Zentgraf, U., Doll, J., Riester, L.: Live and Let Die: The Core Circadian Oscillator Coordinates Plant Life History and Pilots Leaf Senescence. Mol. Plant 11, 351-353 (2018) doi: 10.1016/j.molp.2018.02.001
• Bieker, S., Potschin, M., Zentgraf, U.: Study of Hydrogen Peroxide as a Senescence-Inducing Signal. Methods Mol. Biol. 1744, 173-193 (2018) doi: 10.1007/978-1-4939-7672-0_16
• Bresson, J., Bieker, S., Riester, L., Doll, J., Zentgraf, U.: A guideline for leaf senescence analyses: from quantification to physiological and molecular investigations. J. Ex. Bot. 69, 769-786. (2018) doi:10.1093/jxb/erx246
• Llorca, C.M., Berendzen, K.W., Malik, W.A., Mahn, S., Piepho, H.P., Zentgraf, U.: The Elucidation of the Interactome of 16 Arabidopsis bZIP Factors Reveals Three Independent Functional Networks. PLoS One 10(10): e0139884 (2015) doi: 10.1371/journal.pone.0139884
• Smykowski, A., Fischer, S. M., Zentgraf, U.: Phosphorylation Affects DNA-Binding of the Senescence-Regulating bZIP Transcription Factor GBF1. Plants 4(3), 691-709 (2015) doi:10.3390/plants4030691
• Xie, Y., Huhn, K., Brandt, R., Potschin, M., Bieker, S., Straub, D., Doll, J., Drechsler, T., Zentgraf, U., Wenkel, S.: REVOLUTA and WRKY53 connect early and late leaf development in Arabidopsis. Development 141, 4772-4783 (2014) doi:10.1242/dev.117689
• Marco Llorca, C., Potschin, M., Zentgraf, U.: bZIPs and WRKYs: two large transcription factor families executing two different functional strategies. Front. Plant Sci. 5, Article 169 (2014) doi: 10.3389/fpls.2014.00169
• Potschin, M., Schlienger, S. Bieker, S., Zentgraf, U.: Senescence Networking: WRKY18 is an upstream regulator, a downstream target gene, and a protein interaction partner of WRKY53. J. Plant Growth Regul. 33, 106-118 (2014), Special issue: Plant Senescence, doi: 10.1007/s00344-013-9380-2
• Bieker, S., Zentgraf, U.: Plant Senescence and Nitrogen Mobilization and Signaling, In-tech open access publishing, In: "Senescence and Senescence-Related Disorders", Wang, Z., Inuzuka, H.  (Eds.) ISBN 978-953-51-0997-6; DOI: 10.5772/54392 (2013)
• Bieker, S., Riester, L. Stahl, M. Franzaring, J., Zentgraf, U.: Senescence-specific alteration of hydrogen peroxide levels in Arabidopsis thaliana and oilseed rape spring variety Brassica napus L. cv. Mozart. J. Integr. Plant Biol. 54(8), 540-554, Special issue: Senescence (2012)
• Zentgraf, U., Zimmermann, P., Smykowski, A.: Role of intracellular hydrogen peroxide as signaling molecule for plant senescence, In-tech open access publishing, In: Senescence, Tetsuji Nagata (Ed.), ISBN: 978-953-51-0144-4, DOI: 10.5772/34576 (2012)
• Wierer, S., Peter, S., Elgass, K., Mack, H.G., Bieker, S., Meixner, A.J., Zentgraf, U., Schleifenbaum, F.: Determination of the in vivo redox potential by one-wavelength spectro-microscopy of roGFP. Anal. Bioanal. Chem. 403 (3), 737-744 (2012)
• Wierer, S., Elgass, K., Bieker, S., Zentgraf, U., Meixner, A. J., Schleifenbaum, F.: Determination of the in vivo redox potential using roGFP and fluorescence spectra obtained from one-wavelength excitation. Proc. SPIE 7902, 790211, doi:10.1117/12.873753 (2011)
• Smykowski, A., Zimmermann, P., Zentgraf, U.: G-Box Binding Factor1 reduces CATALASE2 expression and regulates the onset of leaf senescence in Arabidopsis. Plant Physiol. 153, 1321-1331 (2010)
• Miao, Y., Zentgraf, U.: A HECT E3 ubiquitin ligase negatively regulates Arabidopsis leaf senescence through degradation of the transcription factor WRKY53. The Plant Journal 63, 179–188 (2010)
• Zentgraf, U., Laun, T., Miao, Y.: The complex regulation of WRKY53 during leaf senescence of Arabidopsis thaliana. Eur. J. Cell Biol. 89, 133-137 (2010)
• Zentgraf, U.: Catalase regulation during leaf senescence of Arabidopsis. In: Redox Metabolism and longevity relationships in animals and plants. Eds: Foyer C, Faraghar R, Thornalley P J, Garland Science, London (2009)
• Zentgraf, U.: Mit Netz und doppeltem Boden: ein molekulares Regulationsnetzwerk der pflanzlichen Senesezenz im Modellsystem Arabidopsis. Biospektrum 14, 465-468 (2008)
• Miao, Y., Smykowski, A., Zentgraf, U.:  A novel upstream regulator of the WRKY53 transcription during leaf senescence of Arabidopsis thaliana. Plant Biol. 10 (Suppl.1) 110-120 (2008)
• Zentgraf, U, Hemleben V: Molecular cell biology: Are reactive oxygen species regulators of leaf senescence? In: Progress in Botany, Vol. 69, Springer Verlag, Berlin, Heidelberg, New York, pp 117-137 (2008)
• Miao, Y., Laun, T., Smykowski, A., Zentgraf, U.: Arabidopsis MEKK1 can take a short cut: it can directly interact with senescence-related WRKY53 transcription factor on the protein level and can bind to its promoter. Plant Mol. Biol. 65: 63-76.  (2007)
• Miao, Y., Zentgraf U.: The antagonist function of Arabidopsis WRKY53 and ESR/ESP in leaf senescence is modulated by the jasmonic and salicylic acid equilibrium. The Plant Cell 19: 819-830 (2007)
• Zentgraf, U.: Oxidative stress and leaf senescence. In: Senescence processes in plants. Ed: Gan, S. Annual Plant Reviews Vol. 26, Blackwell Publishing, ISBN: 9781405139847, pp 69-86 (2007)
• Dost, C.K., Saraiva, J., Zentgraf, U., Monesi, N., Engels, W., Albuquerque, S.:  Is nitric oxide involved in the tolerance of Calomys callosus as a reservoir host towards Trypanosoma cruzi infection? 52: 49-55 (2006)
• Zimmermann, P., Heinlein, C., Orendi, G., Zentgraf, U.: Senescence specific regulation of catalases in Arabidopsis thaliana (L.) Heynh. Plant Cell Environ. 29: 1049-1060 (2006)
• Volkov, R.A., Komarova, N.Y., Zentgraf, U., Hemleben, V.: Molecular cell biology: epigenetic gene silencing in plants. In: Progr. Botany (Esser, K., Lüttge, U., Beyschlag, W. & Murata, J., Eds.) Progress in Botany Vol. 67, Springer Verlag, Berlin, Heidelberg, New York, pp. 101-133 (2006)
• Zimmerman, P., Zentgraf, U.: The Correlation between oxidative stress and leaf senescence during plant development. Cell. Mol. Biol. Lett. 10: 515-534 (2005)
• Panchuk, I.I., Zentgraf U., Volkov R.A.: Expression of the APX gene family during leaf senescence of Arabidopsis thaliana. Planta 222: 926-32 (2005)
• Zimmermann, P., Zentgraf, U.: Pflanzliche Seneszenz – geordnetes Chaos? Bioforum 28 (6): 30-31 (2005)
• Miao, Y., Laun, T., Zimmermann P., Zentgraf, U.:Targets of the WRKY53 transcription factor and its role during leaf senescence in Arabidopsis thaliana. Plant Mol. Biol. 55 (6): 853-867 (2004)
• Zimmermann, P., Zentgraf, U.: Der Zusammenhang zwischen oxidativem Stress und Blattseneszenz während der Entwicklung von Pflanzen. Gesunde Pflanzen 56: 208-217 (2004)
• Dost, C.K., Saraiva, J., Monesi, N., Zentgraf, U., Engels, W., Albuquerque, S.: Six Trypanosoma cruzi strains characterized by specific gene expression patterns. Parasitol. Res. 94: 134-140 (2004)
• Zentgraf, U., Jobst, J., Kolb, D., Rentsch, D.: Senescence related gene expression profiles of rosette leaves of Arabidopsis thaliana: leaf age versus plant age. Plant Biol. 6, 178-183 (2004)
• Volkov, R.A., Medina, F.J., Zentgraf, U., Hemleben, V.: Molecular Cell Biology: Organization and Molecular Evolution of rDNA, Nucleolar Dominanz, and Nucleolus structure. In: Progress in Botany Vol.65, 106-146, Springer Verlag, Berlin, Heidelberg, 2004
• Fajkus, J., Zentgraf, U.: Structure and maintenance of chromosome ends. In: Telomeres and Telomerases: Cancer and Biology (Eds. Krupp, G., Parwaresch, R.), www.eurekah.com, Bioscience, Gen-Expression, 2002
• Hemleben, V., Hinderhofer, H., Zentgraf, U.: Molecular Cell Biology: Mechanisms and regulation of protein import into the plant cell nucleus. In: Progress in Botany Vol.63, 132-162, Springer Verlag, Berlin, Heidelberg, New York, (2002)
• Orendi, G., Zimmermann, P., Baar, C., Zentgraf, U.: Loss of stress-induced expression of catalase3 during leaf senescence of Arabidopsis thaliana is restricted to oxidative stress. Plant Sci. 161, 301-314 (2001)
• Hinderhofer, K., Zentgraf, U.: Identification of a transcription factor specially expressed at the onset of leaf senescence. Planta 213, 469-473 (2001)
• Hemleben, V., Torres-Ruiz, RA, Schmidt, T., Zentgraf, U.: Molecular Cell Biology: Role of repetitive DNA in nuclear architecture and chromosome structure. In: Progress in Botany Vol.61, 91-117, Springer Verlag, Berlin, Heidelberg, New York, 2000
• Zentgraf, U., Hinderhofer, K., Kolb, D.: Specific association of a small protein with the telomeric DNA-protein complex during the onset of leaf senescence in Arabidopsis thaliana. Plant Mol. Biol. 42, 429-438 (2000)
• Zentgraf, U., Velasco, R., Hemleben, V.: Molecular Cell Biology: Different Transcriptional Activities in the Nucleus. In: Progress in Botany (Behnke et al., eds.) pp. 131-168, Vol. 59, Springer Verlag, Berlin, Heidelberg, New York, 1998
• Zentgraf, U., Hemleben, V.: Molecular Cell Biology: Signal Transduction in Plants. In: Progress in Botany, Vol. 57, 218-234, Springer-Verlag Berlin Heidelberg 1996
• Zentgraf, U., Zinkernagel, I.: A gene encoding a catalase isoform from Arabidopsis thaliana (PGR 96-005). Plant Physiol. 110, 1047 (1996)
• Zentgraf, U.: Telomere-binding proteins of Arabidopsis thaliana. Plant Mol. Biol. 27: 467-475 (1995)
• Hemleben, V., Zentgraf, U.: Structural organization and regulation of transcription by RNA polymerase I of plant nuclear ribosomal RNA genes. In: Plant Promoters and Transcription Factors. Nover, L. (Ed), Results and Problems in Cell Differentiation. pp. 3 - 24, Vol. 20, Springer, Berlin Heidelberg 1994
• Fischer, T.C., Groner, S., Zentgraf, U., Hemleben, V.: Evidence for nucleosomal phasing and a novel protein specifically binding to cucumber satellite DNA. J. Biosciences 49c, 79-86 (1994)
• Zentgraf, U., Hemleben, V.: Nuclear proteins interact with RNA polymerase I promoter and repeated elements of the 5'external transcribed spacer of the rDNA of cucumber in a single-stranded stage. Plant Mol. Biol. 22, 1153-1156 (1993)
• King, K., Torres, R.A., Zentgraf, U., Hemleben, V.: Molecular evolution of the intergenic spacer in the nuclear ribosomal RNA genes of Cucurbitaceae. J. Mol. Evol. 36, 144-152 (1993)
• Hemleben, V., Zentgraf, U., King, K., Borisjuk, N., Schweizer, G.: Middle repetitive and highly repetitive sequences detect polymorphisms in plants. In: DNA-polymorphisms in Eukaryotic Genomes. Kahl, G., Appelhans, H., Kömpf, J., Driesel, A.J. (Eds.). BioTechForum (BTF), Advances in Molecular Genetics, Vol. 5, pp. 157 - 170, Huethig Verlag, Heidelberg, 1992
• Zentgraf, U., Hemleben, V.: Complex formation of nuclear proteins with the RNA polymerase I promoter and repeated elements in the external transcribed spacer of Cucumis sativus ribosomal DNA. Nucl. Acids Res. 20, 3685-3691 (1992)
• Zentgraf, U., King, K., Hemleben, V.: Repetitive sequences are valuable as molecular markers in studies of phylogenetic relationships within the genus Cucumis. Acta Bot. Neerl. 41, 397-406 (1992)
• Zentgraf, U, Ganal, M., Hemleben, V.: Length heterogeneity of the rRNA precursor in cucumber (Cucumis sativus). Plant Mol. Biol. 15, 465-474 (1990)
• Torres, R.A., Zentgraf, U., Hemleben, V.: Species and genus specificity of the intergenic spacer (IGS) in the ribosomal RNA genes of Cucurbitaceae. J. Biosciences 44c, 1029-1034 (1989)