Job Opportunities


Stellenangebote der Universität Tübingen

Assistant Professors / Research Group Leaders (Forschungsgruppenleiter)

20.6.18

The Center for Plant Molecular Biology (ZMBP) at the University of Tübingen invites applications for an

Independent Junior Group Leader

position. The successful candidate will be expected to establish a competitive research program in the area of

Plant Molecular Biology

Particularly outstanding scientists with strong interest and experience in the following areas are encouraged to apply:
cell and developmental biology, mechanics and computational modeling of signaling processes.

The position will be vacant from January 1, 2019 and is initially limited to 6 years.
Salary and social benefits are according to scale A13/E13 of the German Civil Service Regulations. The Center provides fully equipped lab space, funding for staff, start-up money, an independent annual budget and shared equipment funds. The research group will benefit from the ZMBP central service units (greenhouse facilities, plant transformation, cytometry/FACS, microscopy, analytics, IT and administrative support).

For more information see www.zmbp.uni-tuebingen.de

The University of Tübingen is committed to increase the proportion of women in Science and qualified women are particularly encouraged to apply. Equally qualified applicants with disabilities will be given preference.

Applications including CV, publication list and research statement should be sent before August 1, 2018 to:

Prof. Dr. M. Timmermans
Universität Tübingen - ZMBP
Auf der Morgenstelle 32
72076 Tübingen
Germany

marja.timmermansspam prevention@zmbp.uni-tuebingen.de


--Sorry, no open positions available


Postdoctoral scientists (Postdoktoranden)

 

 

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Sorry, no open positions available


Graduate students (Doktoranden)

7.1.19

PhD Position in plant cell biology

Project title: Anionic lipids and mechano-transduction in plant morphogenesis

Research: Most biological processes involve changes in molecular and cell shapes, and such deformations, in essence, involve a mechanical component. Our group at the ZMBP Tübingen investigates the role of membrane lipids at the nexus between plant morphogenesis and mechanics. I discovered that phosphatidylinositol phosphates (PIPs), a class of lipids with important regulatory functions, adopt a stereotypical pattern in the shoot apical meristem, with a specific accumulation at organ boundaries where tensile stress is highly anisotropic (Stanislas et al., 2018). These results question the role of PIPs at the meristem and open the field of biophysics and development to the role of lipids in mechanotransduction.

Using Arabidopsis as a model system, we will alter the PIPs pattern and explore the molecular mechanisms behind the role of PIPs in mechanotransduction. As PIPs are likely involved in many signalling pathways, this approach may shed a new light on meristem biology and morphogenesis in general. The work will include cell biology (with high resolution confocal microscopy), biochemistry, genetics as well as novel micromechanics approaches (microfluidics with protoplasts).

References:

A phosphoinositide map at the shoot apical meristem in Arabidopsis thaliana, Stanislas T, Platre M, Liu M, Rambaud L, Jaillais Y, Hamant H, BMC Biology, 16:20 (2018)

In-vivo analysis of morphogenesis in plants Stanislas T, Hamant O, Traas J, Methods in Cell Biology, 139:203-223 (2017)

A PtdIns(4)P-driven electrostatic field controls cell membrane identity and signalling in plants. Simon ML, Platre MP, Marques Bueno MM, Armengot L, Stanislas T, Bayle V, Caillaud MC, Jaillais Y, Nature Plant, 20, 2, 16089 (2016)

Requirements/Qualifications:

We are looking for a highly motivated Ph.D. student with proven expertise in cell and molecular biology, and Arabidopsis. Prior experiences with confocal microscopy are highly advantageous but not required. Excellent English communication skills as well as teamwork abilities are expected. A master’s degree in molecular biology, biochemistry or corresponding is required.

The position is available from April 01, 2019. Please send your application as a composite pdf-file (letter of motivation stating your research interests, CV, name and addresses of at least two referees) to thomas.stanislas@zmbp.uni-tuebingen.de

The ZMBP is a worldclass center for Plant Biology research and is situated in a brandnew and well-equipped building in the University of Tübingen science campus. The University of Tübingen is an equal opportunity employer and particularly welcomes applications from qualified women and individuals with disabilities. Formal employment procedures will be carried out by the central administration of the University of Tübingen.

 

 

 

13.12.18

PhD position available in plant three-dimensional genomics

A PhD position is available from 1st April 2019 in the laboratory of Dr. Chang Liu
at Zentrum für Molekularbiologie der Pflanzen (ZMBP) in University of Tübingen. This
position remains open until it is filled; the contract is for 3 years (including an initial 6-
month probation period) with a possibility to extend. The salary and benefits are based
on the German public service TV-L pay scale and are commensurate with training and
experience.

Our team works on investigating 3D-chromatin structures in plants, and we aim to
understand the interplay between 3D-chromatin organization and transcriptional
regulation in response to developmental cues and environmental changes. From a
structural point of view, by combining high throughput sequencing, computing, and
modern molecular biology approaches, much of our work has been focused on
integrative genome-wide analysis on chromatin folding, transcriptome, and epigenetic
marks.

You will be working on a project about perinuclear chromatin anchoring in plants. This
project is closely related to our recent findings showing preferential perinuclear
localization of repressed chromatin in Arabidopsis thaliana (PMID: 28385710). You will
be using various molecular and bioinformatic tools to unveil the mechanisms by which
specific chromatin regions are tethered to the nuclear periphery.

To apply, you should have a Master or equivalent degree in Biology or Bioinformatics
(or related areas). Please send your application materials as a single pdf file containing
a detailed curriculum vitae, a motivation letter, and contact details of at least two
referees to: chang.liuspam prevention@zmbp.uni-tuebingen.de

The University of Tübingen is an equal opportunity employer. Disabled candidates will
be given preference over other equally qualified applicants. The University seeks to
raise the number of women in research and teaching and therefore urges qualified
women to apply. The appointment is facilitated by the central administration.
The working language in ZMBP is English, for more details about ZMBP and its
graduate program, please visit:
http://www.zmbp.uni-tuebingen.de/zmbp.html

 

 

15.11.18

PhD Position in Plant-microbe interaction
Project title: Specificity of proteasome regulation during plant immunity

Research: Our group at the ZMBP Tübingen is interested in the role of proteolytic degradation pathways such as the proteasome and autophagy during plant immunity. Recently, we have identified that Pseudomonas syringae pv. tomato DC3000 (Pst) activates autophagy for proteasome degradation and enhanced pathogenicity (Üstün et al., 2018). We aim to study the specificity of proteasome regulation during plant-bacteria interactions by using a combination of cell biological, transcriptomics and biochemical methods. The work will include biochemical, cell biological, RNAseq, ChIP-Seq and genetic approaches using Arabidopsis and Pseudomonas syringae as the primary model organisms.

More information can be found on our lab homepage: http://theustunlab.com/

References:
Üstün S., Hafrén A., Liu Q., Marshall R., Minina E.A., Bozhkov P., Vierstra R., Hofius D. (2018) Bacteria exploit autophagy for proteasome degradation and enhanced virulence in plants. The Plant Cell Mar 2018, 30 (3) 668-685; DOI: 10.1105/tpc.17.00815
Üstün S., Sheikh A., Gimenez-Ibanez S., Jones A., Ntoukakis V., Börnke F. (2016) The proteasome acts as a hub for plant immunity and is targeted by Pseudomonas type-III effectors. Plant Physiology 172: 1941-1958

Requirements/Qualifications:
We are looking for a talented PhD student with proven expertise in cell and molecular biology, and Arabidopsis. Prior experiences with methods to study plant-microbe interactions are highly advantageous but not required. Excellent English communication skills as well as teamwork abilities are expected. A master’s degree in molecular biology, biochemistry or corresponding is required.

The position is available from January 01, 2019. Reviewing of applications will begin immediately and the position will remain open until a suitable candidate is found. Please send your application as a composite pdf-file in English (letter of motivation stating your research interests, CV, name and addresses of at least two referees) via email not later than 04.12.2018: suayib.uestuenspam prevention@zmbp.uni-tuebingen.de

The ZMBP is a world‐class center for Plant Biology research and is situated in a brand-new and well-equipped building in the University of Tübingen science campus. The University of Tübingen is an equal opportunity employer and particularly welcomes applications from qualified women and individuals with disabilities. Formal employment procedures will be carried out by the central administration of the University of Tübingen.

 

 

 

Permanent advertisement

Am Zentrum für Molekularbiologie der Pflanzen (ZMBP), Abt. Entwicklungsgenetik, werden hochmotivierte

Doktorand(inn)en

Bachelor

für DFG-finanzierte Projekte zu den Themen Zellpolarität, Zellkommunikation, Cytokinese gesucht.

Weitere Information in: Weijers et al., 2006, Dev. Cell 10, 265; Geldner et al., 2003, Cell 112, 219; Richter et al., 2007, Nature 448, 488; Reichardt et al., 2007, Curr. Biol. (in press).

Erfahrungen in Genetik, Molekularbiologie, Proteinbiochemie oder Zellbiologie sowie gute Englisch-Kenntnisse sind erwünscht. Bitte senden Sie Ihre Bewerbung mit der Angabe von 3 möglichen Referenzen per email an:

Prof. Dr. Gerd Jürgens, ZMBP-Entwicklungsgenetik, Universität Tübingen,

Auf der Morgenstelle 32, 72076 Tübingen, Tel. 07071/29 78887,

e-mail: gerd.juergens(at)zmbp.uni-tuebingen.de

Permanent advertisement

The Center for Molecular Biology of Plants, Developmental Genetics, is seeking highly qualified

PhD students

Bachelor or MSc students

in the areas of cell polarity, cell-cell communication, cytokinesis (DFG-funded projects). For more information, see Weijers et al., 2006, Dev. Cell 10, 265; Geldner et al., 2003, Cell 112, 219; Richter et al., 2007, Nature 448, 488; Reichardt et al., 2007, Curr. Biol. (in press).

The successful candidates are highly motivated, proficient in English and experienced in genetics, molecular biology, cell biology or biochemistry. Please send your application including names of 3 potential referees by e-mail to:

Prof. Dr. Gerd Jürgens, ZMBP-Entwicklungsgenetik, Universität Tübingen,

Auf der Morgenstelle 32, 72076 Tübingen, Tel. 07071/29 78887,

e-mail: gerd.juergens(at)zmbp.uni-tuebingen.de


Undergraduate students (Bachelor, Master)

6.11.18
 

Master Thesis Project

“Design and Characterization of a Nanosensor for In Vivo Turgor Measurements in Plant Cells”

The turgor of plant cells is crucial for plant stability and survival. Environmental cues such as drought or altered osmotic pressure lead to the change in turgor pressure having many functional consequences for the plant cell.

Therefore, the monitoring of the turgor pressure in the living plant cell is of great interest However, there is presently no technique to follow turgor changes in real time in living plant cells at cellular resolution.

Based on molecular, biochemical and biophysical considerations we, the research groups of Erik Schäffer and Klaus Harter, developed a concept and strategy for the making of a Förster Resonance Energy Transfer (FRET)-based, genetically encoded nanosensor that should facilitate the measurement of dynamic changes in the plant cell´s turgor.

The thesis work is mainly about

  • Cloning of the nanosensor gene on the basis of already available DNA fragments using the Golden Gate technology
  • Transformation of the nanosensor construct into plant cells and analysis of its expression and intracellular localization by (confocal) light microscopy
  • Determination of the nanosensor´s FRET efficiency under dynamic osmotic stress conditions using spectro-microscopical approaches (e.g. Fluorescence Lifetime Imaging: FLIM)

In addition to biology students with molecular background, the work might also be of interest for master students in Nano-Science and Biochemistry.

We offer an innovative and scientifically stimulating environment, and cutting-edge techniques. The position is available immediately.

For further information, please contact:

Prof. Dr. Klaus Harter
ZMBP/Plant Physiology

3. Etage, room 3R19

Auf der Morgenstelle 32

72076 Tübingen, Germany

+49 (0)7071 2972605

klaus.harterspam prevention@zmbp.uni-tuebingen.de

 

 

 

14.8.18

Master and or Bachelor Thesis in Plant Pathogen Interactions (RG El Kasmi)

Our research group in the Department for Plant Physiology at the Center for Plant Molecular Biology (ZMBP), University of Tübingen, is offering the possibility for a highly motivated Master and or Bachelor (of Biology, Biochemistry or Cellular Nanoscience) student to do her/his thesis project in our lab.

We are currently working on the characterization of interactors of a plant immune receptor of the NLR family. We would like to validate the preliminary results (interactions observed in yeast-2-hybrid screen) and to further cell biologically, genetically and biochemically characterize the function of the identified proteins during (NLR-mediated) immunity.
The project will include the following methods:
•    Molecular analysis (cloning, bacterial transformation, etc.)
•    In planta Protein-protein interaction studies (co-immunoprecipitation, BiFC and FRET interaction assays)
•    Genetic studies (crosses, genotyping, etc.)
•    Plant infection assays
We offer an innovative and scientifically stimulating environment, a well-equipped lab as well as an international and cooperative research team.
For applying, please send an email with a short motivation statement to Dr. Farid El Kasmi at farid.el-kasmispam prevention@zmbp.uni-tuebingen.de
For more details about the ZMBP and our research, please visit:
http://uni-tuebingen.de/fakultaeten/mathematisch-naturwissenschaftliche-fakultaet/fachbereiche/zentren/zmbp/res/plant-physiology/research-groups/elkasmi/

 

15.5.18

Master Thesis in Plant Biochemistry

Our research group in the Department for Plant Biochemistry at the Center for Plant Molecular Biology (ZMBP), University of Tübingen, is offering a position for a highly motivated Master student.

We are currently working on the characterization of a plant immunity regulator. We would like to understand the role of phospholipases during plant immune responses. Recent results show a negative regulatory function of a certain PLD and interaction with important key-players of plant innate immunity. The aim of the work will be to validate the preliminary results and to further biochemically characterize the protein.

· The project will include the following methods:

 

We offer an innovative and scientifically stimulating environment, a well-equipped lab as well as an international and cooperative research team. You should apply if you are a biology or biochemistry student who is enthusiastic about science and keen on learning new techniques.

For further information and for applying please contact andrea.gustspam prevention@zmbp.uni-tuebingen.de.

For more details about the ZMBP, please visit:

http://www.zmbp.uni-tuebingen.de/zmbp.html

 



Sorry, no open positions available


Technical staff (Technische Angestellte)

 

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Student lab assistants (Wissenschaftliche Hilfskräfte)

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Administration staff (Verwaltungskräfte)

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Gardeners and Technical Support staff (Gärtnerei- und Werkstattpersonal, Hausmeisterei)

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