Sweet and Blind Spots in E3 Ligase Ligand Space Revealed by a Thermophoresis-Based Assay
Maiwald S*, Heim C*, Hernandez Alvarez B, Hartmann MD. ACS Med Chem Lett (2021)
Architecture and functional dynamics of the pentafunctional AROM complex
Arora Verasztó, H, Logotheti, M, Albrecht, R, Leitner, A, Zhu, H, Hartmann MD. Nat Chem Biol (2020)
De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives
Heim C, Pliatsika D, Mousavizadeh F, Bär K, Hernandez Alvarez B, Giannis A, Hartmann MD. J Med Chem (2019)
On the Origins of Symmetry and Modularity in the Proteasome Family
Fuchs ACD, Hartmann MD. Bioessays (2019)
Chemical Ligand Space of Cereblon
Boichenko I, Bär K, Deiss S, Heim C, Albrecht R, Lupas AN, Hernandez Alvarez B, Hartmann MD. ACS Omega (2018)
The Architecture of the Anbu Complex Reflects an Evolutionary Intermediate at the Origin of the Proteasome System
Fuchs ACD, Alva V, Maldoner L, Albrecht R, Hartmann MD, Martin J. Structure (2017)
A widespread glutamine-sensing mechanism in the plant kingdom
Chellamuthu VR, Ermilova E, Lapina T, Lüddecke J, Minaeva E, Herrmann C, Hartmann MD, Forchhammer K. Cell (2014)