Excellence Strategy

University of Tübingen - Aesculap AG

Neuro-implants, such as brain pacemakers, are used for the treatment of Parkinson's disease. They still have the time-consuming disadvantage of finding the optimal parameters, although being adjusted by a physician, and they do not function on measured physiological parameters. Efforts are made to move towards closed loop systems in order to simplify the adjustment of the system, to save battery, to increase the lifetime and to control the stimulation for each patient individually. One approach is the recording of local field potentials, which in Parkinson's disease show anomalies in the beta-band that are associated with tremor. In addition to the efficiency of the stimulation and thus, the success rate, neuro-implants have a low but existing complication rate. Infections of the implants are to be mentioned here, but also failures of the electronics due to cable breaks of the extension laid under the skin occur regularly.

Based on the evaluations made, the existing infrastructure and the scientific relevance, the group has focused on 2 main areas that are gaining importance in the field of intelligent neuro-implants:

 

Members

Dr. Boris Hofmann, representatives of Aesculap AG
research focus: Intelligent Neuroimplants

Prof. Dr. Tilman Schäffer, representatives of the University of Tübingen
Institut für Angewandte Physik
research focus: NanoBioPhysics