News

17.03.2023

Watching atherosclerosis as it develops

PET/MRI scan image with indicated orientation of scan — PET/MRI image of a mouse with atherosclerosis. The cross-sectional image shows the aortic arch as a bright structure in the center. The yellow glowing region represents an accumulation of potentially dangerous vascular muscle cells. The drawing on the left illustrates the sectional plane of the PET/MRI image.

A team led by IFIB researcher Susanne Feil has developed a new method that can visualize diseased blood vessels. It may help to better understand heart attacks and strokes ‒ while reducing the use of laboratory animals.

The study was published in Circulation Research.

Publication:

Feil S, Stowbur D, Schörg B, Ehrlichmann W, Reischl G, Kneilling M, Pichler B, Feil R. 2023. Non-invasive detection of smooth muscle cell-derived hot spots to study atherosclerosis by PET/MRI in mice. Circ Res 132:747-750. DOI: 10.1161/CIRCRESAHA.122.322296

For further information, please see the press release.

Contact:

Dr. Susanne Feil
University of Tübingen
Interfaculty Institute of Biochemistry (IFIB)
Phone +49 7071 29-72458
susanne.feilspam prevention@uni-tuebingen.de

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