IFIB – Interfakultäres Institut für Biochemie



Watching atherosclerosis as it develops

PET/MRI image of a mouse with atherosclerosis. The cross-sectional image shows the aortic arch as a bright structure in the center. The yellow glowing region represents an accumulation of potentially dangerous vascular muscle cells. The drawing on the left illustrates the sectional plane of the PET/MRI image.

A team led by IFIB researcher Susanne Feil has developed a new method that can visualize diseased blood vessels. It may help to better understand heart attacks and strokes ‒ while reducing the use of laboratory animals.

The study was published in Circulation Research.


Feil S, Stowbur D, Schörg B, Ehrlichmann W, Reischl G, Kneilling M, Pichler B, Feil R. 2023. Non-invasive detection of smooth muscle cell-derived hot spots to study atherosclerosis by PET/MRI in mice. Circ Res 132:747-750. DOI: 10.1161/CIRCRESAHA.122.322296

For further information, please see the press release.


Dr. Susanne Feil
University of Tübingen
Interfaculty Institute of Biochemistry (IFIB)
Phone +49 7071 29-72458
susanne.feilspam prevention@uni-tuebingen.de