07.01.2014

Monday (January, 13) at 13:00, N11 (Auf der Morgenstelle 3)

Vytas Bankaitis, Dept. Molecular and Cellular Medicine, Texas A&M, “New Chemical Strategies for Dissecting Phosphoinositide Signaling Circuits in Eukaryotic Cells”

Guests are cordially welcome!
Gabriel

Selected Publications:
• Mousley, C., Yuan, P., Gaur, N.A., Trettin, K.D., Nile, A.H., Deminoff, S., Dewar, B.J.,Wolpert, M., Macdonald, J.M., Herman, P.K.,
Hinnebusch, A.G., and Bankaitis, V.A. 2012. A sterol binding
protein integrates endosomal lipid metabolism with TOR signaling and nitrogen sensing. Cell 148: 702-715. PMID: 22341443 • Schaaf, G., Ortlund, E.A., Tyeryar, K.R., Mousley, C.J., Ile, K.E., Woolls, M.J., Garrett, T.A., Raetz, C.R.H., Redinbo, M.R., and Bankaitis, V.A. 2008. The functional anatomy of phospholipid binding and regulation of phosphoinositide homeostasis by proteins of the Sec14-superfamily. Molecular Cell 29: 191-206. PMID: 18243114 • Liu, Y., Boukhelifa, M., Tribble, E., Morin-Kensicki, E., Uetrecht, A., Bear, J.E., and Bankaitis, V.A. 2008. The Sac1 phosphoinositide phosphatase regulates Golgi membrane morphology and mitotic spindle organization in mammals. Mol. Biol. Cell 19: 3080-3096. PMID: 18480408 • Alb, J.G. Jr., Phillips, S.E., Wilfley, L.R., Philpot, B.D., and Bankaitis, V.A. 2007. The pathologies associated with functional
titration of phosphatidylinositol transfer protein activity in mice.
J. Lipid Res. 48: 1857-1872.
• Slessareva, J.E., Routt. S.M., Temple, B., Bankaitis, V.A., and Dohlman, H.G. 2006. G protein activation of a PtdIns 3-kinase at the endosome. Cell 126: 191-203. PMID: 16839886 • Vincent, P., Chua, M., Nogue, F., Fairbrother, A., Mekheel, H., Xu,
Y., Allen, N., Bibikova, T.N., Gilroy, S., and Bankaitis, V.A. 2005.
A Sec14p-nodulin domain phosphatidylinositol transfer protein polarizes membrane growth of Arabidopsis root hairs. Journal of Cell Biology 168: 801-812. PMID: 15728190 • Li, X., Rivas, M.P., Fang, M., Marchena, J., Mehrotra, B., Chaudhary, A., Feng, L., Prestwich, G.D., and Bankaitis, V.A. 2002.
Analysis of oxysterol binding protein homolog Kes1p function in regulation of Sec14p-dependent protein transport from the yeast Golgi complex. Journal of Cell Biology 157: 63-77. PMID: 11916983 • Sha, B., Phillips, S.E., Bankaitis, V.A.* and Luo, M.* 1998. Crystal structure of the Saccharomyces cerevisiae phosphatidylinositol transfer protein Sec14p. Nature 391: 506-510. PMID: 9461221 • Kearns, B.G., McGee T.P., Mayinger, P., Gedvilaite, A., Phillips, S.E., Kagiwada, S., and Bankaitis, V.A. 1997. Essential role for
diacylglycerol in protein transport from the yeast Golgi complex.
Nature 387: 101-105. PMID: 9139830
• Cleves, A. E., T. P. McGee, E. A. Whitters, K. Champion, J. R.
Aitken, W. Dowhan, M. Goebl, and V. A. Bankaitis. 1991. Mutations in the CDP-choline pathway for phospholipid biosynthesis bypass the requirement for an essential phospholipid transfer protein. Cell 64:
789-800. PMID: 1997207
• Bankaitis, V. A., J. F. Aitken, A. E. Cleves, and W. Dowhan. 1990.
An essential role for a phospholipid transfer protein in yeast Golgi function. Nature 347: 561-562. PMID: 2215682