Professorship for Quantum Many-Body Theory
The research activities of our group focus on the emergent physical behavior of strongly correlated electron systems. Prominent examples of fascinating phenomena arising from electronic correlations are high-temperature superconductivity or quantum criticality. The impressive technological advancements in the device fabrication strongly stimulated the exploration of new phases of matter. At the same time, the development of new many-body techniques for their theoretical description became a central aspect of the forefront research. In recent years, various renormalization-group approaches lead to significant progress in the understanding of correlated electron systems in and out of equilibrium. In particular, by means of these approaches and of their most recent developments, we investigate the fundamental mechanisms underlying the physical behavior of model systems for materials, cold atomic gases and nanostructures. Homepage
Professorship for Mikrobial Bioactive Compounds
Bacterial resistance to antibiotics spreads at an alarming rate worldwide. New antibiotics devoid of cross-resistance to established antibiotic classes are urgently needed to maintain our standard of treating bacterial infections and to further enable medical interventions dependend on antibiotic co-medication (e.g. complex surgery, transplantation, aggressive chemotherapy).
Two-thirds of all antibiotic classes in therapeutic application today originate from natural products produced by microorganisms. Researchers of the Brötz-Oesterhelt group search among natural and synthetic compounds from diverse sources for new antibacterial agents still active against multi-resistant bacterial isolates.
A special focus is on the elucidation of the molecular mechanisms of action of these new agents by an array of microbiological, biochemical and genetic techniques. Such resistance-breaking compounds usually interfere with new bacterial “targets” or new binding sites at validated targets, thereby demonstrating novel bacterial Achilles heels for antibiotic intervention. Promising agents are further evaluated for their potential to serve as lead structures for antibiotic drug discovery and with respect to their resistance mechanisms. Homepage
Professorship for Romance Philology
My research interests lie in different aspects of synchronic and diachronic linguistics of French, Italian, Spanish and Catalan: verbal morphology, semantics and syntax (in particular aspect and Aktionsart, mode, tense and aspect interfaces, ‘modal uses’ of imperfect, verbal periphrases); philosophy of language, language theory and semiotics; internal and external language history; variational linguistics (especially theories of standardization). My next projects will focus on participles in verbal periphrases of Romance languages as well as on the relevance and the effectiveness of purist strategies and methods in the process of the consolidation of Romance languages. Homepage
Professorship for Nuclear Medicine
Molecular imaging techniques using radiolabeled pharmaceuticals and positron-emission-tomography (PET) for the assessment of pathobiochemical and pathophysiological changes in oncology, neurooncology and neurology.
We aim to use those multi-parametric imaging techniques in order to provide an insight in physiological (adaptive) as well as pathophysiological changes in the brain, which may lead to an individualized treatment stratification. Homepage
Professorship for Islamic Studies
Professorship for Theoretical High Energy Physics
The Theoretical High Energy Physics group investigates the phenomenology of elementary particles via precision calculations for collider experiments at high energies, such as the CERN Large Hadron Collider (LHC). Our aim is an improved understanding of the strong and electroweak interactions that govern the dynamics of elementary particles.
A particular focus of our research is on the physics of the recently discovered Higgs boson. By means of advanced numerical simulations we provide predictions that help to pin down the nature of this particle. Moreover, we try to identify possible signatures of new physics that cannot be accounted for within the Standard Model of elementary particles. Homepage
Professorship for Sinology
My research interests are in Japanese history of religion, with a particular focus on modern and contemporary times. Presently, my research focuses on the fields of gender and religion, as well as medicine and religion in Japan. With regard to the first topic, I investigate the role of gender concepts in the self-understandings of contemporary ordained Buddhist women, thus reconstructing changed interpretations of religious roles. Besides, I examine diverse ways in which religion and medicine are entangled in contemporary Japan, asking for strategies of legitimation and self-positioning among religious actors offering therapeutic practices. Here, Buddhism and new religious movements serve as examples. I am professor for Japanese Studies at the Institute of Asian and Oriental Studies of the University of Tübingen since 2014.
Professorship for Translational Oncology
Main focus of our laboratory is to understand the mechanisms of hematopoietic differentiation and leukemogenic transformation. Topics are: Understanding the pathophysiology of pre-leukemia bone marrow failure syndromes, particularly severe congenital neutropenia (CN, Kostmann syndrome), Identification of new gene mutations in patients with inherited neutropenia and leukemia using NGS and the understanding the mechanisms of G-CSF-triggered myeloid differentiation. In addition we work on Hematopoietic differentiation of iPS cells, Post-translational modification of proteins by de-/acetylation and its role in hematopoietic differentiation and leukemogenic transformation and In vivo modeling of leukemia and neutropenia in humanized NGS mice. We apply multidisciplinary approaches covering different research fields. Homepage
Professorship for Clinical Psychology und Psychotherapy
My research themes focus on mechanisms that cause and maintain pathological eating behavior and body image disturbances in at-risk populations, overweight individuals and individuals with eating disorders. To this end, a variety of designs and methods are used, ranging from fundamental studies (eye tracking, EEG, reaction-time tasks) to laboratory-based behavioral studies, ecological momentary assessment (EMA) studies and applied clinical studies (treatment processes and treatment effects).
Professorship for Neuro-Oncology
The field of Neuro-Oncology is dedicated to patients with tumors in the central and peripheral nervous system. Our work requires an interdisciplinary network of experts. Unfortunately, most neurooncological tumors are incurable. Thus, our laboratroy research focuses on gaining more insight into the biology of these tumors as a prerequisite of finding new therapeutic approaches that can then be translated into clinical application. Homepage
Professorship for Developemental Genetics
The research in our group follows two major directions. In one, we are studying the role of small non-coding RNAs as mobile instructive signals in development. In the other, we are dissecting mechanisms underlying shoot stem cell homeostasis and organogenesis. In our research we use maize, Arabidopsis thaliana, and the moss Physcomitrella patens as model organisms, as each offers unique experimental advantages and because comparative studies can provide an evolutionary perspective on key genetic pathways. Homepage
Professorship for Theoretical Informatics
Ulrike von Luxburg's research area is the theory of machine learning algorithms. Her current focus is on unsupervised learning, such as the statistical analysis of algorithms on random networks and the statistical foundations of comparison-based data analysis. Homepage