Publications 2010

Albert M, Jehle AK, Mueller K, Eisele C, Lipschis M, Felix G. 2010. Arabidopsis thaliana pattern recognition receptors for bacterial elongation factor Tu and flagellin can be combined to form functional chimeric receptors. J. Biol. Chem. 285:19035-19042.

Alt S, Burkard N, Kulik A, Grond S, Heide L. 2010. An artificial pathway to 3,4-dihydroxybenzoic acid allows generation of a new aminocoumarin antibiotic recognized by catechol transporters of E. coli. Chem. Biol. 18(3):304-13. Highlighted in Nature Biotechnology May 2011

Alvarez BH, Gruber M, Ursinus A, Dunin-Horkawicz S, Lupas AN, Zeth K. 2010. A transition from strong right-handed to canonical left-handed supercoiling in a conserved coiled-coil segment of trimeric autotransporter adhesins. J. Struct. Biol. 170:236-245.

Autenrieth SE, Linzer TR, Hiller C, Keller B, Warnke P, Koberle M, Bohn E, Biedermann T, Buhring HJ, Hammerling GJ, Rammensee HG, Autenrieth IB. 2010. Immune Evasion by Yersinia enterocolitica: Differential Targeting of Dendritic Cell Subpopulations In Vivo. PLoS Pathog 6:e1001212.

Brock AK, Willmann R, Kolb D., Grefen L, Lajunen HM, Bethke G, Lee J, Nürnberger T, Gust AA. 2010. The Arabidopsis mitogen-activated protein kinase phosphatase PP2C5 affects seed germination, stomatal aperture, and abscisic acid-inducible gene expression. Plant Physiol. 153:1098-1111.

Burian M, Rautenberg M, Kohler T , Fritz M, Krismer B, Unger C, Hoffmann WH, Peschel A, Wolz C, Goerke C. 2010. Temporal expression of adhesion factors and activity of global regulators during establishment of Staphylococcus aureus nasal colonization. J. Infect. Dis. 201: 1414-21.

Burian M, Wolz C, Goerke C. 2010. Regulatory adaptation of Staphylococcus aureus during nasal colonization of humans. PLoS One 5:e10040.

Dunin-Horkawicz S, Lupas AN. 2010. Measuring the conformational space of square four-helical bundles with the program samCC. J. Struct. Biol. 170:226-235.

Espinosa J, Brunner T, Fiedler N, Forchhammer K, Muro-Pastor AM, Maldener I. 2010. DevT (Alr4674), resembling a Ser/Thr protein phosphatase, is essential for heterocyst function in the cyanobacterium Anabaena sp. PCC 7120. Microbiology. 156(12):3544-55. PMID: 20798164.

Flinspach K, Westrich L, Kaysser L, Siebenberg S, Gomez-Escribano J, Bibb M, Gust B, Heide L. 2010. Heterologous expression of the biosynthetic gene clusters of coumermycin A1, clorobiocin and caprazamycins in genetically modified Streptomyces coelicolor strains. Biopolymers 93:823-832.

Gallo G, Renzone G, Alduina R, Stegmann E, Weber T, Lantz AE, Thykaer J, Sangiorgi F, Scaloni A, Puglia AM. 2010. Differential proteomic analysis reveals novel links between primary metabolism and antibiotic production in Amycolatopsis balhimycina. Proteomics. 10:1336-58.

Goerke C, Wolz C. 2010. Adaptation of Staphylococcus aureus to the cystic fibrosis lung. International journal of medical microbiology 300:520-525.

Gökay O, Kühner D, Los M, Götz F, Bertsche U, Albert K. 2010. An Efficient Approach for the Isolation, Identification and Evaluation of Antimicrobial Plant Components on an Analytical Scale Demonstrated on the Example Radix Imperatoriae. Anal. Bioanal. Chem. 398: 2039-47.

Gust AA, Brunner F, Nürnberger T. 2010. Biotechnological concepts for improving plant innate immunity. Curr. Opin. Biotechnol. 21: 204-210.

Hirschhausen N, Schlesier T, Schmidt MA, Götz F, Peters G, Heilmann C. 2010. A novel staphylococcal internalization mechanism involves the major autolysin Atl and heat shock cognate protein Hsc70 as host cell receptor. Cell Microbiol. 12(12):1746-64. doi: 10.1111/j.1462-5822.2010.01506.x.

Kanchan K, Linder JU, Winkler K, Hantke K, Schultz A, Schultz JE. 2010. Transmembrane signaling in chimeras of the Escherichia coli aspartate and serine chemotaxis receptors and bacterial class III adenylyl cyclases J. Biol. Chem. 285, 2090-99.

Lehr U, Schütz M, Oberhettinger P, Ruiz-Perez F, Donald JW, Palmer T, Linke D, Henderson IR, Autenrieth IB. 2010. C-terminal amino acid residues of the trimeric autotransporter adhesin YadA of Yersinia enterocolitica are decisive for its recognition and assembly by BamA. Mol Microbiol 78:932-46.

Mainiero M, Goerke C, Geiger T, Gonser C, Herbert S, Wolz C. 2010. Differential target gene activation by the Staphylococcus aureus two-component system saeRS. J. Bacteriol. 192: 613-23.

Müller P, Müller-Anstett, Wagener J, Gao Q, Kaesler S, Schaller M, Biedermann T, Götz F. 2010. The Staphylococcus aureus lipoprotein SitC colocalizes with Toll-like receptor 2 (TLR2) in murine keratinocytes and elicits intracellular TLR2 accumulation. Infect. Immun. 78: 4243-4250.

Müller-Anstett MA, Müller P, Albrecht T, Nega M, Wagener J, Gao Q, Kaesler S, Schaller M, Biedermann T, Götz F. 2010. Staphylococcal peptidoglycan co-localizes with Nod2 and TLR2 and activates innate immune response via both receptors in primary murine keratinocytes. PLoS One 5: e13153.

Oberhettinger P, Schütz M, Raddatz G, Keller H, Autenrieth IB, Linke D. 2010. The sequence of the pYV virulence plasmid from Yersinia enterocolitica strain WA-314 biogroup 1B serotype O:8. Plasmid. 65(1):20-4.

Pasztor L, Ziebandt AK, Nega M, Schlag M, Haase S, Franz-Wachtel M, Madlung J, Nordheim A, Heinrichs DE, Götz F. 2010. Staphylococcal major autolysin (atl) is involved in excretion of cytoplasmic proteins. J. Biol. Chem. 285(47): 36794-36803.

Postel S, Küfner I, Beuter C, Mazzotta S, Schwedt A, Borlotti A, Halter T, Kemmerling B, Nürnberger T. 2010. The multifunctional leucine-rich repeat receptor kinase BAK1 is implicated in Arabidopsis development and immunity. Eur. J. Cell Biol. 89:169-174.

Pramanik A, Zhang F, Schwarz H, Schreiber F, Braun V. 2010. ExbB protein in the cytoplasmic membrane of Escherichia coli forms a stable oligomer. Biochemistry 49:8721-8728.

Remmert M, Biegert A, Linke D, Lupas AN, Söding J. 2010. Evolution of outer membrane beta-barrels from an ancestral beta beta hairpin. Mol. Biol. Evol. 27: 1348-1358.

Schlag M, Biswas R, Krismer B, Köhler T, Zoll S, Yu W, Schwarz H, Peschel A, Götz F. 2010. Role of staphylococcal wall teichoic acid in targeting the major autolysin Atl. Mol Microbiol 75:864-873.

Schütz M, Weiss EM, Schindler M, Hallström T, Zipfel PF, Linke D, Autenrieth IB. 2010. Trimer stability of YadA is critical for virulence of Yersinia enterocolitica. Infect Immun 78:2677-90.

Senyürek I, Klein G, Kalbacher H, Deeg M, Schittek B. 2010. Peptides derived from the human laminin alpha4 and alpha5 chains exhibit antimicrobial activity. Peptides, 31:1468-1472.

Shimada T, Park BG, Wolf AJ, Brikos C, Goodridge HS, Becker CA, Reyes CN, Miao EA, Aderem A, Götz F, Liu GY, Underhill DM. 2010. Staphylococcus aureus evades lysozyme-based peptidoglycan digestion that links phagocytosis, inflammasome activation, and IL-1beta secretion. Cell Host Microbe 7:38-49.

Siebenberg S, Kaysser L, Wemakor E, Heide L, Gust B, Kammerer B. 2010. Identification and structural elucidation of new caprazamycins from Streptomyces sp. MK730-62F2 by liquid chromatography/electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS). Rapid Commun Mass Spectrom. 2011 Feb 28;25(4):495-502. doi: 10.1002/rcm.4889.

Sievers S, Ernst CM, Geiger T, Hecker M, Wolz C, Becher D, Peschel A. 2010. Changing the phospholipid composition of Staphylococcus aureus causes distinct changes in membrane proteome and membrane-sensory regulators. Proteomics 10: 1685-1693.

Thykaer J, J Nielsen J, Wohlleben W, Weber T, Gutknecht M, Lantz AE, Stegmann E. 2010. Increased glycopeptide production after overexpression of shikimate pathway genes being part of the balhimycin biosynthetic gene cluster. Metab Eng. 12:455-461.

Volz T, Nega M, Buschmann J, Kaesler S, Guenova E, Peschel A, Röcken M, Götz F, Biedermann T. 2010. Natural Staphylococcus aureus-derived peptidoglycan fragments activate NOD2 and act as potent costimulators of the innate immune system exclusively in the presence of TLR signals. FASEB J. 2010 Oct;24(10):4089-102.

Weidenmaier C, McLoughlin RM, Lee JC. 2010. The zwitterionic cell wall teichoic acid of Staphylococcus aureus provokes skin abscesses in mice by a novel CD4+ T-cell-dependent mechanism. PLoS One. 5(10):e13227.

Zanger P, Holzer J, Schleucher R, Scherbaum H, Schittek B, Gabrysch S. 2010. Severity of Staphylococcus aureus Infection of the Skin is Associated with Inducibility of Human β-Defensin 3, but not Human β-Defensin 2. Infect Immun 78: 3112-3117.

Zoll S, Pätzold B, Schlag M, Götz F, Kalbacher H, Stehle T. 2010. Structural basis of cell wall cleavage by staphylococcal autolysin. PLoS Pathog. 6: e1000807.


Stegmann E, Frasch HJ, Wohlleben W.2010.Glycopeptide biosynthesis in the context of basic cellular functions. Curr Opin Microbiol. 2010 Oct;13(5):595-602. doi: 10.1016/j.mib.2010.08.011. Epub 2010 Oct 1. Review.


Braun V. 2010. Outer membrane signaling in gram-negative bacteria. In: Bacterial Signaling, (R. Krämer and K. Jung, Eds.), Wiley-VCH Publ. Comp. Weinheim.

Linder JU, Schultz JE. 2010. Transmembrane Receptor Chimeras to Probe HAMP Domain Function. in: Methods in Enzymology 471: Two-Component Signaling Systems, (M.I. Simon, B.R. Crane, and A. Crane eds.) pp. 115-123.