Uni-Tübingen

Sub-project B05: H2O2 perception and signaling: the role of AHK5

Principle Investigator

Prof. Dr. Klaus Harter

Universität Tübingen

ZMBP, Pflanzenphysiologie

Auf der Morgenstelle 1,

72076 Tübingen

Tel 07071 - 29 72605

Fax 07071 - 29 3287

klaus.harterspam prevention@zmbp.uni-tuebingen.de


Prof. Dr. Thilo Stehle

Universität Tübingen

IFIB, Strukturbiologie

Hoppe-Seyler-Str. 4, 72076 Tübingen

Tel 07071 - 29 73043

FAX 07071 - 29 5565

thilo.stehlespam prevention@uni-tuebingen.de

Summary

Histidine kinases (AHKs) play an important role in the integration of multiple endogenous and environmental signals in Arabidopsis. In project B05 we would like to analyze the atomic structure of the histidine kinase 5 (AHK5) and the function of AHK5 in the perception and signaling of H2O2 in the context of environmentally modified root growth and development. In addition we would like to study, how H2O2-dependent signals are integrated by AHK5-dependent processes with other signaling cascades and how this can result in specific cellular and physiological outputs.