If it bites, the spider can secrete venom. This venom can cause severe skin damage. However, this species of spider is not considered to be aggressive, is nocturnal, and shy of humans. The consulting expert therefore assesses the risk as very low.
In the unlikely event of a bite, the risk is very low according to a study, compared to the dangers we expose ourselves to every day, such as in traffic. The study, which documented spider bites in Brazil over a period of seven years, concludes that two percent of documented bites lead to more serious cutaneous problems, i.e., damage to the skin. 0.03 percent of bites (1 in 3,000 bites) were fatal.
Source: E. Marques da Silva et al. Loxosceles Spider Bites in the State of Paraná, Brazil: 1993-2000. J. Venom. Anim. Toxins incl. Trop. Dis., 2006, 12, 1, p.111.